• Korean Journal of Biological Psychiatry
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• v.22 no.2
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• pp.29-33
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• 2015

The brain maintains homeostasis and normal microenvironment through dynamic interactions of neurons and neuroglial cells to perform the proper information processing and normal cognitive functions. Recent post-mortem investigations and animal model studies demonstrated that the various brain areas such as cerebral cortex, hippocampus and amygdala have abnormalities in neuroglial numbers and functions in subjects with mental illnesses including schizophrenia, dementia and mood disorders like major depression and bipolar disorder. These findings highlight the putative role and involvement of neuroglial cells in mental disorders. Herein I discuss the physiological roles of neuroglial cells such as astrocytes, oligodendrocytes, and microglia in maintaining normal brain functions and their abnormalities in relation to mental disorders. Finally, all these findings could serve as a useful starting point for potential therapeutic concept and drug development to cure unnatural behaviors and abnormal cognitive functions observed in mental disorders.

• Korean Journal of Agricultural Science
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• v.40 no.3
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• pp.191-196
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• 2013

This study was conducted to investigate the effect of temperature during transportation and continuing shelf-life on fruit quality and the occurrence of physiological disorder to set up the appropriate exportation temperature condition in Asian pear (Pyrus pyrifolia Nakai) 'Hanareum'. In the experiment of simulated exportation headed for USA, the fruits transported at $1^{\circ}C$ showed less weight loss than those of $5^{\circ}C$. Market temperature appeared as a key factor for keeping freshness of exported pear fruits rather than transportation temperature. Quality factors such as high flesh firmness and low incidence of fruit rot and physiological disorders including core breakdown and pithiness were attained at the fruits maintained at $18^{\circ}C$. Approximately two times higher incidence of physiological disorders and of fruit decay rates were observed in the fruits distributed at $25^{\circ}C$ than the those of $18^{\circ}C$. Therefore, temperature management during marketing resulted as an important factor for maintaining fruits quality in the process of pear fruit exportation.

• Clinical and Experimental Pediatrics
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• v.49 no.1
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• pp.1-5
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• 2006

Several physiological skin changes such as vernix caseosa, cutis marmorata, physiologic desquamation, and sebaceous hyperplasia have been described in the neonatal period. There are also clinical characteristics of skin peculiar to neonate and infancy. Skin disorders observed during neonatal and infancy period can be divided into transient skin lesions, birth marks, and other diseases. Transient skin lesions include milia, sebaceous gland hyperplasia, erythema neonatorum, transient neonatal pustular melanosis, and acne neonatorum. Nevocellular nevus, mongolian spot, vascular malformation, hemangioma, epidermal nevus, and sebaceous nevus belong to birth marks. There are several common skin diseases such as miliaria, diaper dermatitis, atopic dermatitis, seborrheic dermatitis, and cutaneous candidiasis.

• The Korean Journal of Pain
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• v.27 no.1
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• pp.16-22
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• 2014

Psychosomatic disorders are defined as disorders characterized by physiological changes that originate partially from emotional factors. This article aims to discuss the psychosomatic disorders of the oral cavity with a revised working type classification. The author has added one more subset to the existing classification, i.e., disorders caused by altered perception of dentofacial form and function, which include body dysmorphic disorder. The author has also inserted delusional halitosis under the miscellaneous disorders classification of psychosomatic disorders and revised the already existing classification proposed for the psychosomatic disorders pertaining to dental practice. After the inclusion of the subset (disorders caused by altered perception of dentofacial form and function), the terminology "psychosomatic disorders of the oral cavity" is modified to "psychosomatic disorders pertaining to dental practice".

• Horticultural Science & Technology
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• v.17 no.6
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• pp.737-741
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• 1999

We surveyed the physiological disorders of fruit vegetables grown in the greenhouse in Kyungbuk province in 1998. Greenhouses used for cultivation were mostly single or multi-span iron pipe houses covered with polyethylene film. Single span greenhouses were used for strawberry, oriental melon and watermelon. Fifty six percent of the surveyed farms was a mono-cropping system for oriental melon and tomato. There were greenhouses used for successive cultivation for 10 years or more for strawberry and oriental melon in Koryeong and Seongju. Varieties of fruit vegetables cultivated were diverse, especially in cucumber and watermelon. In strawberry, malformed fruits were observed most frequently in March and the small fruits at late harvest period. Leaf chlorosis, stunt plants and runner outbreak were also found during the growing season. In tomato, occurrence of malformed fruits was severe from March to May, and occurrence of cracked fruits and blossom- end rot was also severe in October and November. The self topping and abnormal stem in tomato were problem in hydroponic cultures in August and November, respectively. Malformed cucumber fruits, such as curved, club shaped, irregular shaped and narrow necked, occurred at late season. Umbrella-shaped leaf in cucumber in summer were caused by calcium deficiency. Most serious disorders were fermented and malformed fruits occurring from March to May in oriental melon, and cracked fruits occurring from April to May in watermelon. At late growing stage of melons the leaf chlorosis occurred with complex symptoms of leaf disease. Growers had little knowledge on physiological disorders, and also on diagnose and measures to cure the disorders. Most growers pointed out that poor soil environment and temperature management in the greenhouse as the main causes of physiological disorders.

• Molecules and Cells
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• v.45 no.11
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• pp.781-788
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• 2022

Proline plays a multifaceted role in protein synthesis, redox balance, cell fate regulation, brain development, and other cellular and physiological processes. Here, we focus our review on proline metabolism in neurons, highlighting the role of dysregulated proline metabolism in neuronal dysfunction and consequently neurological and psychiatric disorders. We will discuss the association between genetic and protein function of enzymes in the proline pathway and the development of neurological and psychiatric disorders. We will conclude with a potential mechanism of proline metabolism in neuronal function and mental health.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.28 no.3
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• pp.328-333
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• 1983

Due to fast industrialization and reduced agricultural population, there has been increased farm mechanization to reduce the labor requirement. In rice production, mechanical transplanting has been increasingly popular due to the heavy labor requirement in hand transplanting and development of convenient transplanters. For mechanical transplanting, rice seedlings is grown in boxes with limited soils under super dense population, thus short period of exposure to unfavorable temperature and poor water management would cause severe damage to rice seedlings such as seedling damping off and the similar physiological disorders. Several chemicals were evaluated for their effectiveness to control the disease and disorders, and other effects as plant growth stimulants. 3-hydroxy-5-methylisoxazole-a soil fungicide, Metalozyl-a fungicide which controls mildew, SF 8002-the composite of above two chemicals, and Isoprothiolane-a fungicide which controls rice blast were found to be effective controling seedling damping off and similar physiological disorders, and improvement of physiological characteristics of the seedlings such as the amount of bleeding sap, rooting ability, negative geotrophism, and regrowth after cutting. The results indicated that the chemicals will be very effective raising healthy seedlings even under unfavorable environments by the improvement of physiological activities of seedlings and preventing seedling damping off and the similar physiological disorders.

• Proceedings of the Korean Society for Agricultural Machinery Conference
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• 1996.06c
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• pp.632-637
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• 1996

An expert system for cucumber disease and nutritional disorders(ESCD) was developed using HCLIPS in which several interface programs were added to CLIPS developed in NASA. The knowledges for constructing knowledge base was obtained from interviews with farmers, agrochemical vendors and employees of agrochemical company. The ESCD is able to diagnose eleven diseases and twelve nutritional disorders which farmers, agrochemical vendors and employees of agrochemical company. The ESCD is able to diagnose eleven diseases and twelve nutritional disorders which could frequently found in fields and greenhouses. Validation of ESCD by twenty -four experts proved a possibility of its practical use for diagnosing cucumber diseases and nutritional disorders in the future.

• Proceedings of the Korean Society of Crop Science Conference
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• 1991.10a
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• pp.22-22
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• 1991

• Korean Journal of Agricultural Science
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• v.44 no.3
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• pp.332-338
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• 2017

This study was conducted to investigate the effect of 1-methylcyclopropene (1-MCP), a known ethylene action inhibitor, on fruit quality and incidence of physiological disorders during a simulated marketing period in new mid-season Asian pear (Pyrus pyrifolia Nakai) 'Changjo'. Flesh firmness of untreated control fruits was maintained with a hardness of 20.2 N until day 14 of simulated marketing but decreased rapidly to 6.2 N at day 21 of simulated marketing; losing its commercial quality. However, the firmness of 1-MCP treated fruits remained high (> 20.7 N) during the same period. Quality indices such as soluble solids content and titratable acidity in 'Changjo' pear did not show any significant differences during simulated marketing period regardless of 1-MCP treatment. For the difference in skin color, redness ($a^*$) tended to increase as simulated marketing period became longer, and 1-MCP treatment delayed this change by 7 days compared to the untreated fruits. No decrease occurred in ethylene production level with 1-MCP treatment in 'Changjo' pear. Meanwhile, 1-MCP treated pears showed a significantly lower respiration rate compared to the untreated fruits. Also, 1-MCP treatment effectively reduced the incidence of physiological disorders including internal flesh browning and mealiness symptoms during simulated marketing periods of 21 and 14 days, respectively. Therefore, we conclude that the use of 1-MCP is recommended for quality maintenance and for prevention of physiological disorders during simulated marketing periods of ${\geq}7days$ for mid-season Asian pear 'Changjo'.