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Research trends and clinical applications of neural mobilization in Korea: A scoping review (신경가동술의 국내 연구 동향과 임상적 활용: 주제범위 문헌고찰)

  • Lee, Eun-Kyung;Kim, Jin-Hyun;Lee, Jung-Han;Cho, Eun-Byul
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.16 no.1
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    • pp.53-66
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    • 2021
  • Objectives The purpose of this scoping review is to investigate the trends and gaps in existing research on neural mobilization in Korea and to suggest further directions for study. Methods A scoping review was sequentially conducted according to the five steps outlined by Arksey and O'Malley, and the PRISMA-ScR checklist. We searched five domestic databases (RISS, DBpia, KISS, ScienceON, and KMBASE) and identified relevant literature reported until April 15, 2021. The key search terms used were "Neural mobilization" and "Neurodynamic". Results Of the 1383 studies identified in the search, 50 were finally selected. Of these, 45 studies were in the field of medicine and pharmacy and physical therapy as the most common sub-field. Thirty-eight of the 50 studies (76%) were randomized controlled trials. Neural mobilization was most frequently used in the treatment of stroke (n = 13) and of various neuromusculoskeletal diseases such as cervical radiculopathy (n = 8) and low back pain (n = 5). The main targets of neural mobilization were the median nerve (n = 20) and sciatic nerve (n = 14). The most commonly used technique for neural mobilization was that developed by Butler and Jones in 1991 (n = 10). Conclusions This is the first scoping review of neural mobilization in Korea. We believe that further research on neural mobilization with other types of research design is necessary to investigate the utility of neural mobilization and to establish standard protocols. Our findings indicate that neural mobilization can be considered as an intervention for neuromusculoskeletal diseases in Korean medicine.

Research on User Experience Under the New Retailing Mode: Using the interactive marketing mode of the Estee Lauder POP-UP store as an example (새 소매 모델 방식에서의 사용자 경험 연구: 에스티로더 팝업스토어에서 인터랙티브 마케팅을 예로 들어보자)

  • Liang, Lan;Pan, Young-Hwan
    • Journal of Digital Convergence
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    • v.19 no.6
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    • pp.343-353
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    • 2021
  • The beauty industry of China POP-UP store service, has entered the peak development period. This paper takes China Estee Lauder POP-UP store as an example, based on the user experience of interactive marketing mode in Beauty POP-UP store under the new retailing model. The paper aims to establish a system interaction design process integrating online and offline to help enterprises complete the sustainable development of marketing services. To achieve this goal, this study uses questionnaires to investigate the key elements of user experience, customer journey map to determine the user pain points, and completes the design of the new system process. This process can provide designers with a new perspective through experimental verification, with high timeliness and practicability. It also promotes the collaborative optimisation and upgrading of physical retail and online retail and provides theoretical support and practical basis for other enterprises.

Analysis of HPV Prevalence in Pairs of Cervical and Urine Samples from the Same Woman

  • Kim, Dong Hyeok;Jin, Hyunwoo;Lee, Kyung Eun
    • Biomedical Science Letters
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    • v.27 no.1
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    • pp.28-34
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    • 2021
  • The main cause of cervical cancer is a persistent infection with high-risk human papillomavirus (HR-HPV). Cervical cancer is reported as a preventable cancer in more than 80% of cases with early diagnosis and appropriate treatment. Papanicolaou test (Pap test) has been a global strategy to prevent cervical cancer, and recently, HPV test has been reported to be effective against cervical cancer and precancerous lesions. However, pelvic examinations give patients anxiety, discomfort, pain, distress, and psychological stress. HPV test via a urine sample caused less physical and psychological stress and more advantage than the Pap test. Therefore, it is necessary to study the usefulness of the HPV test for easy-to-collect urine samples. A total of 220 samples were collected from a pair of cervical and urine samples from 110 women and only 108 pairs of samples out of 110 were used because 2 cases were not amplified by β-globin. Among 108 pairs of cervical and urine samples, the prevalence of HPV was 37.0% (40/108) in cervical samples, 34.3% (37/108) in urine samples and HR-HPV was 22.2% (24/108) in cervical samples, 18.5% (20/108) in urine samples. In this study, urine samples showed a lower positive rate of HPV than cervical samples. There were many variables that could affect the condition of the urine sample. However, the HR-HPV agreement rate of the cervix and urine samples was 94.44% and the Kappa value was 0.823, which was "almost perfect". Through these results showed the significance of cervical cancer screening using a urine sample. Cervical screening is crucial, as cervical cancer can be prevented in more than 90% of cases. Urine samples collected by non-invasive methods may have the potential advantage of increasing acceptance of cervical cancer screening. Therefore, it is necessary to develop a new cervical cancer screening strategy using urine samples through further study based on the results of this study.

Seizure after Subdural Hematoma Treated with Combination Western-Korean Medicine

  • Jeong, Jae Eun;Lee, You Jung;Choi, Yeon Ah;Park, Jang Mi;Lee, Seung Min;Jo, Na Young;Lee, Eun Yong;Lee, Cham Kyul;Roh, Jeong Du
    • Journal of Acupuncture Research
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    • v.38 no.1
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    • pp.72-78
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    • 2021
  • Combined Western-Korean medicine treatments were given to a 67-year-old woman with late onset seizures who underwent surgical drainage of a subdural hematoma. Clonazepam and herbal medicine was prescribed. Acupuncture, moxibustion, cupping, chuna, and physical therapy were also performed. The frequency and intensity of seizures was assessed using the Chalfont Seizure Severity Scale. The seizure index score improved from 25 at admission to 0 at discharge. Pain in the right upper extremity reduced from 10 to 0 on the visual analogue scale and muscle strength increased from Grade 3 to 5 in Medical Research Council Scale for the Manual Muscle Test. At the time of hospitalization, the manual muscle strength tests for the affected shoulder, elbow, wrist, and grip strength were 30%, 60%, 10%, 5%, respectively, which improved almost 100% by discharge. Further studies using combined Western-Korean medicine for seizures after strokes are necessary to determine the most effective treatment.

A Case Study of Korean Medical Treatment for Indigestion and Abdominal Pain after Gastrectomy (위절제술 후 발생한 소화불량 및 복통에 대한 한방 치료 증례 보고)

  • Han, Aram;Lee, Hyun-Jin;Cho, Yun-jae;Keum, Chang-Yul;Yoon, Chae-rim;Choi, Su-hyun;Ha, Na-yeon;Kim, Jinsung
    • The Journal of Internal Korean Medicine
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    • v.43 no.2
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    • pp.201-211
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    • 2022
  • Objective: This case study reports the effects of treating a gastric cancer patient who had undergone gastrectomy with Korean medicine. Methods: After gastrectomy, a 77-year-old female patient received acupuncture, electroacupuncture, herbal medicine (Banhabaekchulchunma-tang, Banhahubak-tang), and moxibustion for one month. Results: After treatment, changes were observed in the patient's numeric rating scale (from 7 to 2); visual analog scale (from 8.7 to 2.6); Short Form-36 Health Survey scores (physical from 20 to 48 and mental from 14 to 53); Functional Dyspepsia-Related Quality of Life results (from 84 to 41); and Korean Nepean Dyspepsia Index (from 63 to 32). Conclusion: Korean medical treatment for dyspepsia following gastrectomy is worthy of further research.

Changes of Cognitive Function and Health-related Quality of Life among the Elderly Living alone through the Participation in Cognitive Program (인지프로그램 참여에 따른 독거노인들의 인지기능과 건강관련 삶의 질의 변화)

  • Son, Sung-Min;Bak, Ah-Ream
    • Journal of Korea Entertainment Industry Association
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    • v.15 no.3
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    • pp.279-287
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    • 2021
  • The purpose of this study is to analyze the changes of the cognitive function and health-related quality of life. Study subjects were 35 elderly living alone and they participated in the cognitive program for 8 weeks regularly. The assessment of cognitive function was used by the Loewenstein occupational therapy cognitive assessment battery and the orientation, visual attention, spatial perception, motor praxis, visuomotor organization, thinking operation, and attention. The assessment of health-related quality of life was used by the Short form-8 health survey and the gerneral health condition, physical function and role, pain, vitality, social function, mental health, and emotional role. As the results, all the results of variables showed the statistically significant increase after the participation in the cognitive program. To improve the cognitive function and health quality of life of the elderly living alone, the participation in the cognitive program should be considered.

Efficiency of PDNR (Polydeoxyribonucleotide) extraction from various plant species and its in vitro wound healing activity (다양한 식물에서의 PDRN(Polydeoxyribonucleotide) 추출 수율 비교 및 상처치유 효능 분석)

  • Song, Mi-Hee;Choi, Moon-Hyeok;Jeong, Jin-Hyoung;Lee, Sang-Sik;Jeong, Woo-Young
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.15 no.5
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    • pp.387-395
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    • 2022
  • PDRN (Polydeoxyribonucleotide) is a DNA-derived polymer that promotes self-renewal of damaged cells and tissues as a tissue regeneration active material. PDRN is a DNA fragment cut into small sizes by various physical or chemical methods. When administered to the body, PDRN binds and stimulates the adenosine A2A receptor on the surface of tissue cells to promote cell regeneration, accelerate wound healing, and reduce pain. Although PDRN is prepared from testis or semen of fish in most cass, PDRN extraction from various plants species was performed in the present study. Among 7 tested plant species, the highest DNA yield and purity was obtained form mugwort (Chrysanthemum coronarium, C.c), followed by broccoli (Brassica oleracea, B.o). Then, we evaluated the in vitro wound healing capacity of PDRNs prepared from these two selected plants. PDRN from C.c and B.o. significantly stimulated the wound healing process at ㎍/ml range. The present study suggests that PDRN from plant species can be an effective alternative to PDRN from marine organism.

Mineralized Undifferentiated Duodenal Carcinoma in a Shih-Tzu Dog

  • Lee, Jiyeong;An, Soyon;Hwang, Gunha;Go, Woohyun;Lee, Jong-Bong;Noh, Seul Ah;Lee, Dongbin;Song, Joong-Hyun;Hwang, Tae Sung;Lee, Hee Chun
    • Journal of Veterinary Clinics
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    • v.39 no.5
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    • pp.258-263
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    • 2022
  • An eight-year-old, intact female, Shih-Tzu, weighing 4.5 kg presented with complaints of anorexia, pale mucous membrane, and vomiting for the past 5 days. On physical examination, nausea, abdominal pain, and melena were noted. On hematologic examination, severe anemia and thrombocytosis were identified. On radiographs examination, soft tissue opacity with small faint mineral opacity mass in the mid-abdomen and two mineral opacity regions in the cranial aspect of mass were identified. Ultrasonographic findings showed thickening of descending duodenal wall with loss of layering and mineralization within the duodenal wall and mesentery adjacent to the duodenal lesion. Computerized tomography showed circumferential wall thickening of descending duodenum with mineralization. Mineralization of the mesentery and mesenteric lymph nodes was identified. Based on the diagnostic imaging, the tentative diagnosis was descending duodenal tumor with dystrophic mineralization. Endoscopy revealed mucosal hemorrhage and erythema within the descending duodenum and stomach. Surgery was performed, and mineralization in the pancreatic tail to duodenum and mesentery was found. Resection of the duodenum, regional lymph node, and mineralized pancreatic region and the duodenal anastomosis were performed. The histologic examination revealed a high-grade undifferentiated duodenal carcinoma with metastases to the regional lymph node and mesentery. The patient was managed with supportive therapy for 8 days and discharged. The patient was followed up for 5 months and there were no complications.

Spinal Epidural Lipomatosis Secondary to Hypothyroidism in a Siberian Husky Dog

  • Jeong, Ju-Young;Hwang, Tae-Sung;Song, Kun-Ho;Song, Joong-Hyun
    • Journal of Veterinary Clinics
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    • v.39 no.5
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    • pp.235-239
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    • 2022
  • A 10-year-old neutered male Siberian Husky presented with paraparesis and severe lethargy. On physical examination, the patient was unable to weight-bear and walk and exhibited significant muscle mass loss in both hindlimbs and generalized truncal alopecia with a dull coat of hair. On neurological examination, cranial lumbar vertebral pain, hind limb cross-extensor reflex, delayed hindlimb postural reaction, upper motor neuron bladder dysfunction, and total absence of cutaneous trunci reflex were identified. Computed tomography revealed diffuse idiopathic skeletal hyperostosis and spondylosis deformans of the cervical and thoracolumbar vertebrae. In addition, a generalized decrease in bone mineral density of the vertebrae was identified. Magnetic resonance imaging showed hyperplasia of the epidural fat compressing the spinal cord in the thoracolumbar region and concurrent mild multiple intervertebral disc herniations. No specific findings were observed in cerebrospinal fluid analysis. Blood analysis of thyroid function revealed decreased total T4 and free T4 levels, and increased TSH levels. The patient was tentatively diagnosed with spinal epidural lipomatosis (SEL) secondary to hypothyroidism. The patient was treated with levothyroxine, firocoxib, and gabapentin. Clinical signs gradually improved, and the patient showed normal ambulation 40 days after treatment initiation. SEL is extremely rare in dogs. To the best of our knowledge, this is the first case report of SEL secondary to hypothyroidism that was treated conservatively. Secondary SEL can be sufficiently managed by treating the underlying cause, if possible.

Evaluation of Efficacy for Menopausal Syndrome with Natural Dyed Apparel (천연염색의류의 갱년기 증후군에 대한 효능 평가)

  • Seo, Tae Soon;Jang, Eun Jin;Kim, Jeong Ja;Kim, Hee Sook;Koo, Jin Suk
    • The Korea Journal of Herbology
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    • v.32 no.6
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    • pp.31-39
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    • 2017
  • Objectives : Menopausal symptoms are characteristic symptoms which are occur in women before and after menopause. In Western medicine, hormone therapies are mainly used but patients show reluctance because they exhibit serious side effects. In Oriental medicine, there are also limits to the treatment. So I tried to find a new easily accessible treatment. I performed the experiments to verify the effect of natural dyed apparel with Indigo and Schisandra fruit. Methods : This experiment was performed on 30 women who were experiencing menopausal symptoms. We checked the participant's general condition through questionnaire and physical condition with inbody test and made natural-dyed living suit style dresses. We asked the women to wear the apparel for four weeks. They checked for changes in symptoms weekly with kupperman's index. Results : The main symptoms of participants are sweating, hot flushes, joint pain. After wearing of the apparel, there were decreased hot flushes, sleep improvement, psychological stability etc. According to the kupperman's index, patients with mild symptoms were 13.3% at first week to start the experiment but four weeks later, patients with mild symptoms were increased to 50%. On the other hand, patients with severe symptoms were decreased 33.3% to 6.7%. In the test results, there was a significant decrease in 1, 2 and 3 weeks, there was a decrease in 4 weeks but no significance in the figure Conclusion : Natural dyed apprel with Indigo and Schisandra fruit was effective on treating women who were experiencing menopausal symptoms.