• Asian Journal of Atmospheric Environment
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• 제9권1호
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• pp.86-90
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• 2015

Temperature was considered to estimate the minimum detectable absorption coefficient of aerosol particles from photothermal spectroscopy. Light energy absorbed by subsequent emission from the aerosol results in the heating of the aerosol sample and consequently causes a temperature change as well as changes in thermodynamic parameters of the sample. This thermal effect is the basis of photothermal spectroscopy. Photothermal spectroscopy has several types of techniques depending on how the photothermal effects are detected. Photothermal interferometry traces the photothermal effect, refractive index, using an interferometer. Photoacoustic spectroscopy detects the photothermal effect, sound wave, using a microphone. In this study, it is suggested that the detection limit for photothermal spectroscopy can be influenced by the introduction of a slip correction factor when the light absorption is determined in a high temperature environment. The minimum detectable absorption coefficient depends on the density, the specific heat and the temperature, which are thermodynamic properties. Without considering the slip correction, when the temperature of the environment is 400 K, the minimum detectable absorption coefficient for photothermal interferometry increases approximately 0.3% compared to the case of 300 K. The minimum detectable absorption coefficient for photoacoustic spectroscopy decreases only 0.2% compared to the case of 300 K. Photothermal interferometry differs only 0.5% point from photoacoustic spectroscopy. Thus, it is believed that photothermal interferometry is reliably comparable to photoacoustic spectroscopy under 400 K.

• Current Optics and Photonics
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• 제5권5호
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• pp.554-561
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• 2021

Indocyanine green (ICG) is a cyanine dye that has been used in medical diagnostics based on fluorescence imaging, and in medical therapy based on the photothermal effect. It is important to systematically understand the photothermal effect and fluorescence characteristics of ICG simultaneously. By varying a number of conditions such as laser power density, laser irradiation wavelength, concentration of ICG solution, and exposure time of laser irradiation, the intensity properties of fluorescence and the temperature change induced by the photothermal effect are measured simultaneously using a charge-coupled-device camera and a thermal-imaging camera. The optimal conditions for maximizing the photothermal effect are determined, while maintaining a relatively long lifetime and high efficiency of the fluorescence for fluorescence imaging. When the concentration of ICG is approximately 50 ㎍/ml and the laser power density exceeds 1.5 W/cm², the fluorescence lifetime is the longest and the temperature induced by the photothermal effect rapidly increases, exceeding the critical temperature sufficient to damage human cells and tissues. The findings provide useful insight into the realization of effective photothermal therapy, while also specifying the site to be treated and enabling real-time treatment monitoring.

• 공업화학
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• 제32권3호
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• pp.312-319
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• 2021

광열 치료(photothermal therapy)란 빛을 조사하여 열을 발생시킴으로써 정상세포보다 열에 약한 비정상 세포, 특히 암세포를 선택적으로 괴사시키는 치료법이다. 본 연구에서는 광열 치료를 위한 카르복실화된 환원 그래핀옥사이드(reduced graphene oxide with carboxyl groups, CRGO)-골드나노막대(gold nanorod, AuNR) 나노복합체를 합성하고자 하였다. 이를 위해 그래핀옥사이드(graphene oxide, GO)를 고온에서 선택적으로 환원, 박리하여 CRGO를 합성하였고, AgNO₃의 양에 따라 AuNR의 길이를 조절하여 880 nm에서 강한 흡광 특성을 나타내는 AuNR를 합성하여 광열 인자로 사용하였다. 일반적인 방법으로 환원된 RGO에 비해 CRGO에 상대적으로 많은 카르복실기가 결합되어 있음을 FT-IR, 열 중량 분석 및 형광 분석을 통해 확인하였다. 또한, RGO에 비해 많은 carboxyl group이 결합된 CRGO는 수용액상에서 우수한 안정성을 나타내었다. 정전기적 상호작용을 통해 합성된 CRGO-AuNR 나노복합체는 약 317 nm의 균일한 크기와 좁은 크기 분포를 보였다. CRGO-AuNR 나노복합체는 두 가지 광열 인자인 CRGO와 AuNR의 synergistic effect로 인하여 조직 투과도가 우수한 근적외선 880 nm 레이저의 조사에 의한 광열 효과가 AuNR보다 2배 이상 향상 되는 것을 확인하였다. 또한, 광열 효과에 의한 암세포 독성 분석 결과, CRGO-AuNR 나노복합체가 가장 우수한 세포 독성 특성을 나타내었다. 따라서 CRGO-AuNR 나노복합체는 안정된 분산성과 향상된 광열 효과를 기반으로 항암 광열 요법 분야에 응용될 수 있을 것으로 기대된다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2005년도 창립60주년 기념 추계 학술대회
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• pp.25.2-25.2
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• 2005

• 한국정밀공학회지
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• 제24권4호
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• pp.147-152
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• 2007

UV laser ablation of polyimide is a combination of photochemical and photothermal mechanism. Photochemical mechanism is that molecular bonds are broken by photon energy and photothermal is evaporation and melt expulsion. When the laser processing, the etching depth needs to be calculated for prediction of processing result. In this paper, in order to predict the laser etching depth of polyimide by UV laser with the wavelength of 355nm, the theoretical model which includes both the photothermal and the photochemical effect was introduced. The model parameters were obtained by comparing with experimental results. The 3rd harmonic $Nd:YVO_4$ laser system was used in the experiment. From these experimental and theoretical results, the laser ablation of a polyimide was verified to achieve the highest quality microstructure.

• Journal of Industrial and Engineering Chemistry
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• 제67권
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• pp.429-436
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• 2018

Targeted intracellular delivery of therapeutic agents is one of the great challenges for cancer treatment. Aptamers that bind to a variety of biological targets have emerged as new targeting moieties with high specificity for targeted cancer therapy. In this study, near-infrared (NIR) light-absorbing hollow gold nanocages (AuNCs) were synthesized and conjugated with AS1411 aptamer to achieve cancer-targeted photothermal therapy. AuNC functionalized with PEG and AS1411 (AS1411-PEG-AuNC) exhibited selective cellular uptake in breast cancer cells due to selective binding of AS1411 to nucleolin, a protein that is over-expressed in cancer cells over normal cells. As a result, AS1411-PEG-AuNC showed cancer-targeted photothermal activity. This study demonstrates that aptamer-conjugated AuNCs are effective tumor-targeting photothermal agents.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2023년도 가을학술발표대회논문집
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• pp.223-224
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• 2023

This study compared the curing temperature of the bubble sheet and the photothermal insulation sheet incorporating carbon-based photothermal materials to reduce concrete curing time as a part of shortening construction period. As a result of the experiment, bubble sheet with photothermal material B is judged to be effective in shortening the curing time under hot environment.

• Bulletin of the Korean Chemical Society
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• 제34권9호
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• pp.2795-2799
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• 2013

Irradiation of gold nanorods (GNRs) with laser light corresponding to the longitudinal surface plasmon oscillation results in rapid conversion of electromagnetic energy into heat, a phenomenon commonly known as the photothermal effect of GNRs. Herein, we propose a facile strategy for increasing the photothermal conversion efficiency of GNRs by integration to form graphene oxide (GO) nanocomposites. Moreover, conjugation of iron oxide (IO) with the GO-GNR nanohybrid allowed magnetic enrichment at a specific target site and the separated GO-IO-GNR assembly was rapidly heated by laser irradiation. The present GO-IO-GNR nanocomposites hold great promise for application in various biomedical fields, including surface enhanced Raman spectroscopy imaging, photoacoustic tomography imaging, magnetic resonance imaging, and photothermal cancer therapy.

• Bulletin of the Korean Chemical Society
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• 제17권8호
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• pp.682-685
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• 1996

Photothermal properties depend on the characteristics of energy transfer processes in solution. In this study, a time-resolved single beam thermal lens experiment in various solvents is employed to investigate the energy coupling effects which govern the energy transfer processes. Interestingly, it is observed that the behaviour of the photothermal propagation in solution depends on the property of solution and the concentration of solute in a single beam thermal lens configuration. These characteristics lead us to consider the solute-solvent coupling effects as well as the solvent-solvent interactions.

• 한국정밀공학회지
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• 제24권2호
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• pp.134-139
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• 2007

Usually nanosecond pulsed laser processing of metal is mainly affected by the thermal ablation. Many studies of the theoretical analysis and modeling to predict the laser ablation of metal are suggested on the basis of the photothermal mechanism at higher laser fluence. In this paper, we investigate the etching depth and laser fluence of laser ablation of copper foils and propose the simplified SSB Model(Srinivasan-Smrtic-Babu model) to study the photothermal effect of nanosecond pulsed laser ablation. The experimental results show that the photothermal ablation of the 355nm DPSS $NdYVO_{4}$ laser is useful to process the copper thin foils.