• Archives of Pharmacal Research
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• 제11권4호
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• pp.285-291
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• 1988

2-mercaptoethanol, thioglycolic acid, glutathione, 3-mercapto-1, 2-propanediol and 3-mercapto-2-butanol showed catalytic activities on the hydrolysis of $\alpha$-amino-phenylacetonitrile to phenylglycineamide at the rate of 12.19 $\times$ $10^{-2}$, 8.03 $\times$ $10^[-2}$, 6.83 $\times$ $10^{-2}$, 8.60 $\times$ $10^{-2}$ and 6.04 $\times$ $10^{-2}$ mM $min^{-1}$, respectively. hte hydrolysis rate was faster in buffer than in water. The hydrolysis of the nitrile compound to phenylglycine was limited.