• The Journal of Advanced Prosthodontics
• /
• v.11 no.5
• /
• pp.253-261
• /
• 2019

PURPOSE. To evaluate the influence of cyclic loading on phase transformation of zirconia abutments and to compare the effectiveness of three different quantitative ageing assessment techniques. MATERIALS AND METHODS. Thirty two Y-TZP prostheses fabricated from two brands, InCoris ZI and Ceramill ZI, were cemented to titanium bases and equally divided into two subgroups (n=8): control group without any treatment and aged group with cyclic loading between 20 N and 98 N for 100,000 cycles at 4 Hz in distilled water at $37^{\circ}C$. The tetragonal-to-monoclinic phase transformation was assessed by (i) conventional x-ray diffraction (XRD), (ii) micro x-ray diffraction (${\mu}XRD$), and (iii) micro-Raman spectroscopy. The monoclinic-phase fractions (M%) were compared by two-way ANOVA. RESULTS. InCoris Zi presented significantly higher M% than Ceramill Zi in both control and aged groups (P<.001). Both materials exhibited significant phase transformation with monoclinicphase of 1 to 3% more in aged groups than controls for all three assessment techniques. The comparable M% was quantified by both ${\mu}XRD$ and XRD. The highest M% was assessed with micro-Raman. CONCLUSION. Cyclic loading produced significant phase transformation in tested Y-TZP prostheses. The micro-Raman spectroscopy could be used as an alternative to XRD and ${\mu}XRD$.

• Elastomers and Composites
• /
• v.56 no.2
• /
• pp.72-78
• /
• 2021

A phase-change material (PCM) is a material that has the ability to delay heat transfer by absorbing heat from its environment or releasing heat to its environment while its phase changes from solid to liquid or liquid to solid at a specific temperature. As it is applied, it can contribute to environmental conservation such as energy savings and carbon dioxide emission reduction. In order for a PCM to store and release heat, the volume change during its phase transition should be large, and thus a phase transition space is required. When a PCM is used as a polymer additive, it is confined within the polymer, and there is no phase transition space; thus, its ability to absorb and release heat is significantly reduced. Therefore, in this study, porous silica was used to provide EVA/PCM compounds with sufficient space for their phase transition, and to improve the compatibility between the EVA and PCM, modified silica is used: surface-modified 5 wt% silica with 3-methacryloxypropyltrimethoxysilane. The compound was prepared and compared with the silica compound. The presence or absence of the modified silica surface modification was confirmed using Fourier-transform infrared spectroscopy and thermogravimetric analysis, the heat capacity of the compound was evaluated based on a differential scanning calorimetry analysis, and its mechanical strength and morphology were determined using scanning electron microscopy.

• Journal of Internet Computing and Services
• /
• v.19 no.6
• /
• pp.133-145
• /
• 2018

Medical systems incurred accidents may result in significant damage for human being. Therefore, performing hazard analysis is important for medical system which is to identify hazard for preventing the accidents and minimizing the potential harm. Hazard analysis that is applied medical systems are difficult to apposite selected, because difference of analysis methods and applied development lifecycle is caused by objective of hazard analysis. It is required to select appropriate hazard analysis at concept phase during development lifecycle, owing to basic requirement elicitation to mitigate or prevent hazard based on identified hazard at concept phase. In this paper, hazard analysis methods, PHA and STPA, are compared at concept phase in which both methods have been applied on the medical system. As a result of compared methods, hazard analyst can be selected optimized hazard analysis methods for concept phase of the medical systems.

• Journal of Advanced Marine Engineering and Technology
• /
• v.41 no.1
• /
• pp.83-90
• /
• 2017

In this paper, a sound reception system using a phase difference of whistle signals is proposed and analyzed based on spectral analysis. The proposed system receives whistle signals from four microphones installed in four different directions with 90-degree intervals between them. The proposed algorithm detects the phase of each received signal based on spectral analysis and estimates the direction of the whistle signal by obtaining the phase difference between the received signals from two adjacent microphones. Furthermore, we theoretically analyze the phase difference between two adjacent received signals according to their arrival angles and implement the proposed system using a DSP chip. In addition, the operation of the proposed algorithm are verified using the implemented system in a laboratory environment. Experimental results show that the proposed scheme can well estimate the direction of the whistle signal.

• Nuclear Engineering and Technology
• /
• v.44 no.7
• /
• pp.807-816
• /
• 2012

The Three Mile Island Unit 2 (TMI-2) accident has been studied extensively, as part of both post-accident technical assessment and follow-up computer code calculations. The models used in computer codes for severe accidents have improved significantly over the years due to better understanding. It was decided to reanalyze the severe accident scenario using current state of the art codes and methodologies. This reanalysis was adopted as a part of the joint standard problem exercise for the Atomic Energy Regulatory Board (AERB) - United States Regulatory Commission (USNRC) bilateral safety meet. The accident scenario was divided into four phases for analysis viz., Phase 1 covers from the accident initiation to the shutdown of the last Reactor Coolant Pumps (RCPs) (0 to 100 min), Phase 2 covers initial fuel heat up and core degradation (100 to 174 min), Phase 3 is the period of recovery of the core water level by operating the reactor coolant pump, and the core reheat that followed (174 to 200 min) and Phase 4 covers refilling of the core by high pressure injection (200 to 300 min). The base case analysis was carried out for all four phases. The majority of the predicted parameters are in good agreement with the observed data. However, some parameters have significant deviations compared to the observed data. These discrepancies have arisen from uncertainties in boundary conditions, such as makeup flow, flow during the RCP 2B transient (Phase 3), models used in the code, the adopted nodalisation schemes, etc. In view of this, uncertainty and sensitivity analyses are carried out using simulation based techniques. The paper deals with uncertainty and sensitivity analyses carried out for the first three phases of the accident scenario.

• FOCUS: LIFE SCIENCE
• /
• no.1
• /
• pp.3.1-3.7
• /
• 2024

The article discusses the critical role of chromatography in the analysis and purification of proteins in biopharmaceuticals, emphasizing the importance of comprehensive characterization for ensuring their safety and efficacy. It highlights the use of Avantor® ACE® HPLC columns for the separation and purification of proteins, focusing on the analysis of intact proteins using reversed-phase liquid chromatography (RPLC) with fully porous particles. This article also details the application of different mobile phase additives, such as TFA and formic acid, and emphasizes the advantages of using type B ultra-pure silica-based columns for efficiency and peak shape in biomolecule analysis. Additionally, it addresses the challenges of analyzing intact proteins due to slow molecular diffusion and introduces the concept of solid-core (or superficially porous) particles, emphasizing their benefits over traditional porous particles for the analysis of therapeutic proteins. Furthermore, it discusses the development of Avantor® ACE® UltraCore BIO columns, specifically designed for the high-efficiency separation of large biomolecules, such as proteins, and demonstrates their effectiveness in achieving high-resolution separations, even for higher molecular weight proteins like monoclonal antibodies (mAbs). In addition, it underscores the complexity of analyzing and characterizing intact protein biopharmaceuticals, requiring a range of analytical techniques and the use of wide-pore stationary phases, operated at elevated temperatures and with relatively shallow gradients. It highlights the comprehensive range of options offered by Avantor® ACE® wide pore columns, including both fully porous and solid-core particles, bonded with a variety of complementary stationary phase chemistries to optimize selectivity during method development. The use of ultrapure and highly inert base silica is emphasized for enabling the use of lower concentrations of mobile phase modifiers without compromising analyte peak shape, particularly beneficial for LC-MS applications. Then the article concludes by emphasizing the significance of reversed-phase liquid chromatography and its compatibility with mass spectrometry as a valuable tool for the separation and analysis of intact proteins and their closely related variants in biopharmaceuticals.

• Nuclear Engineering and Technology
• /
• v.40 no.5
• /
• pp.397-408
• /
• 2008

This paper describes the application of a software fault tree analysis (FTA) as one of the analysis techniques for a software safety analysis (SSA) at the design phase and its analysis results for the safety-critical software of a digital reactor protection system, which is called the KNICS RPS, being developed in the KNICS (Korea Nuclear Instrumentation & Control Systems) project. The software modules in the design description were represented by function blocks (FBs), and the software FTA was performed based on the well-defined fault tree templates for the FBs. The SSA, which is part of the verification and validation (V&V) activities, was activated at each phase of the software lifecycle for the KNICS RPS. At the design phase, the software HAZOP (Hazard and Operability) and the software FTA were employed in the SSA in such a way that the software HAZOP was performed first and then the software FTA was applied. The software FTA was applied to some critical modules selected from the software HAZOP analysis.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
• /
• v.18 no.7
• /
• pp.757-765
• /
• 2007

OFDM system is an excellent high speed transmission method but it is seriously sensitive to the phase noise and IQ imbalance. Therefore, in this paper, we analyze the communication performance of the OFDM communication system with IQ imbalance and phase noise. Phase noise's variance can be calculated by integral calculus of phase noise power spectrum. From simulation results, it can be shown that the BER performances show different change according to the phase noise variance and IQ imbalance amount. When amplitude imbalance is ${\varepsilon}$=0.2; 0.3; 0.4 and phase imbalance is ${\phi}=10^0$, and distribution of phase noise is ${\sigma}^2=0.012$, BER is degraded by 2.88 dB, 3.61 dB, 4.09 dB in $10^{-5}$ in the respect of the SNR penalty.

• Journal of computational fluids engineering
• /
• v.20 no.4
• /
• pp.14-20
• /
• 2015

Without electirc power to cool down the hot reactor core, passive systems utilizing natural circulation are becoming a big specialty of recent neculear systems after the severe accident in Fukusima. When we consider the natural circulation in a pool, thermal mixing phenomena may start from single phase circulation and can continue to two phase condition. Since the CUPID code, which has been developed for two-phase flow analysis, can deal with the phase transition phenomena, the CUPID would be pertinent to natural convection problems in single- and two-phase conditions. Thus, the CUPID should be validated against single- and two-phase natural circulation phenomena. For the first step of the validation process, this study is focused on the validation of single-phase natural circulation. Moreover, the CUPID code solves the fluid properties by the relationship to pressure and temperature from the steam table considering non-condensable gas effects, so that the effects from variable properties are included. Simple square thermal cavity problems are tested for laminar and turbulent conditions against numerical and experimental data. Throughout the investigation, it is found that the variable properties can affect the flow field in laminar condition, but the effect becomes weak in turbulence condition, and the CUPID code implementing steam table is capable of analyzing single phase natural circualtion phenomena.

• Progress in Medical Physics
• /
• v.3 no.2
• /
• pp.43-57
• /
• 1992

Phase detector techique provides a unique probe to membrane recycling phenomenon by enabling dynamic monitoring of cell membrane capacitance. However, it has inherent errors due to constant changes in measurement environments. The present study analyzed several error sources to develope application criteria of this technique. and the following was found based on a theoretical analysis. The initial phase angle has to be appropriately selected to minimize the error due to perturbation of access and membrane conductances. Excitation frequency is also important to determine the initial phase angle. However. deviation of the phase angle from a predetermined initial value during the measurement period does not affect capacitance estimation to a significant degree. Despite an appropriate initial phase selection an error in scaling factor is expected for a large increase in capacitance during exocytosis. which may be overcome by iteratively correcting the scaling factor over the measurement period. These results will provide a useful guideline in practical application of this technique.