• 제목/요약/키워드: pharmacology

검색결과 9,474건 처리시간 0.032초

The Influence of Bisphenol A on the Thyroid Hormone System in vivo

  • Cho, Mi-Young;Jung, Ki-Kyung;Nam, Kyung-Tak;Kang, Ju-Hye;Kang, Seog-Youn;Chung, Hye-Joo;Kim, Ju-Il;Lee, Young-Don;Na, Han-Kwang
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.185.3-186
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    • 2003
  • It is well-known that bisphenol A(BPA), an industrial raw material for polycarbonate and epoxy resins, shows estrogenic activity. Recent research from our laboratory has shown that SPA disrupts interaction between thyroid hormone and its receptor in a non-competitive manner, and alters the thyroid-hormone dependent expression of growth hormone(GH) and prolactin(PRL). (omitted)

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METHAMPHETAMINE-INDUCED CYTOTOXICITY IN HUMAN SEROTONERGIC CELLS

  • Kim, Kyu-Bong;Suh, Soo-Kyung;Lee, Bo-Kyung;Park, Chang-Won;Seo, Kyung-Won;Kim, Jong-Won;Kim, Kwang-Jin;Kim, Jae-Hee;Park, Chan-Woong
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2002년도 Molecular and Cellular Response to Toxic Substances
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    • pp.190-190
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    • 2002
  • Methamphetamine (META) is a psychostimulant and has become popular recreational drug of abuse in many countries. The neurotoxic damage caused by METH is characterized by degeneration of the dopaminergic and serotonergic systems in striatum and hippocampus.(omitted)

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Adenosine inhibits the death in immunostimulated murine astrocytes deprived of glucose

  • Choi, Min-Sik;Chang, Eun-Sook;Park, Ji-Woong;Yoo, Byung-Kwon;Park, Gyu-Hwan;Lee, Woo-Jong;Yoon, Suh-Young;Ko, Kwang-Ho
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.302.1-302.1
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    • 2002
  • Adenosine has been associated with protection of neurons from noxious stimuli both by receplor- and non receptor-mediated mechanisms. Previously we have reported that immunostimulated astrocytes were highly vulnerable to glucose deprivation. In the present study we investigated the effect of adenosine and related nucleotides on the susceptibility of immunostimulated astrocytes to glucose deprivation. (omitted)

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