• Computers and Concrete
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• v.13 no.3
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• pp.361-375
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• 2014

The moisture transport in underground concrete was experimentally investigated and the nonlinear model of moisture transport considering the effects of water diffusion, hydration of cementicious materials and water permeability was proposed. The consumed moisture content by self-desiccation could be firstly calculated according to evolved hydration degree of cement and mineral admixtures. Furthermore, the finite differential method was adopted to solve the moisture transport model by linearizing the nonlinear moisture diffusion coefficient. The comparison between experimental and calculated results showed a good agreement, which indicated that the proposed moisture model could be used to predict moisture content evolution in underground concrete members with drying-wetting boundaries.

• Journal of Ocean Engineering and Technology
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• v.20 no.6 s.73
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• pp.35-40
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• 2006

In recent years, there's been strong demand for seawalls that havea gentle slope and permeability that serveswater affinity and disaster prevention from wave attack. The aim of this study is to examine wave transformation, including wave run-up that propagates on the coastal structures. A numerical model based on the weak nonlinear dispersive Boussinesq equation, together with the unsteady nonlinear Darcy law for fluid motion in permeable layer, is developed. The applicability of this numerical model is examined through Deguchi and Moriwaki's hydraulic model test on the permeable slopes. From this study, it is found that the proposed numerical model can predict wave transformation and run-up on the gentle slope with a permeable layer, but can't show accurate results for slopes steeper than about 1:10.

• KIEE International Transactions on Electrophysics and Applications
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• v.3C no.4
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• pp.146-154
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• 2003

This paper describes various characteristics of the new compounds for cable jackets and model cables advanced in waterproof performance in order to essentially solve the problems of underground (URD) distribution class power cable failures. Several compounds were manufactured by the inclusion of additives to base resins available in Korea and tested for basic property, mechanical and electrical characteristics. Two model cables were created by using the compounds determined in the test as being the most appropriate for new structured model cable jacket material. The waterproof performance and mechanical strength of the new cable jackets were verified by applicable tests. As a result, MDPE and LLDPE compounds were superior as cable jackets in both mechanical and electrical characteristic aspects when compared with conventional PVC. In addition, the model cables composed of the new compounds based on MDPE showed good quality results in the water permeability test.

• Electrical & Electronic Materials
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• v.9 no.9
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• pp.891-899
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• 1996

A model for predicting the characteristics of elastic ferromagnetic materials having a moving gap was presented. Based on the model parameters concerning behavior of material, such as the instantaneous field intensity, attractive force between the poles, length of gap, and the induced current/ emf in the circuit can be determined from the numerical integrations of the governing equations derived. From the results of the model it is found that when dc emf is imposed on the circuit the current sharply rise and fall for very short duration then stabilize at extremely low level which depends mainly on elasticity, permeabilities and ratio of resistivity. Subsequently output emf is shown stabilized at constant value which depends on the previous parameters as well as the resistivity ratio of primary to secondary circuit after sufficient progress of time.

• Journal of Soil and Groundwater Environment
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• v.9 no.1
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• pp.1-11
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• 2004

Foam reduces the mobility of gas phase in porous media to overcome gravity override and to divert acid into desired layers in the petroleum industry and to enhance the efficiency of environmental remediation. Recent experimental studies on foam show that foam exhibits a remarkably different flow rheology depending on the flow regime. This study, for the first time, focuses on the issues of foam diversion process under the conditions relevant to groundwater remediation, combining results from laboratory linear-flow experiments and a simple numerical model with permeability contrasts. Linear flow tests performed at two different permeabilities (k = 9.1 and 30.4 darcy) confirmed that two flow regimes of steady-state strong foams were also observed within the permeability range of shallow geological formations. Foam exhibited a shear-thinning behavior in a low-quality regime and near Newtonian rheology in a high-quality regime. Data taken from linear flow tests were incorporated into a simple numerical model to evaluate the efficiency of foam diversion process in the presence of permeability contrasts. The simple model illustrated that foam in the high-quality regime exhibited a successful diversion but foam in the low-quality regime resulted in anti-diversion, implying that only foam in the high-quality regime would be applicable to the diversion process. Sensitivity study proved that the success of diversion process using foam in the high-quality regime was primarily controlled by the limiting capillary pressures (${P_c}{^*}$) of the two layers of interest. Limitations and implications are also discussed and included.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.40 no.11
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• pp.689-695
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• 2016

The performance of proton exchange membrane fuel cells (PEMFC) is strongly related to the water flow and accumulation in the gas diffusion layer (GDL) and catalyst layer. Understanding the behavior of fluid from the characteristics of the media is crucial for the improvement of the performance and design of the GDL. In this paper, a numerical method is proposed to calculate the design parameters of the GDL, i.e., permeability, tortuosity, and effective diffusivity. The fluid flow in a channel filled with randomly packed hard spheres is simulated to validate the method. The flow simulation was performed by lattice Boltzmann method with bounce back condition for the solid volume fraction in the porous media, with different values of porosities. Permeability, which affects the flow, was calculated from the average pressure drop and the velocity in the porous media. Tortuosity, calculated by the ratio the average path length of the randomly injected massless particles to the thickness of the porous media, and the resultant effective diffusivity were in good agreement with the theoretical model. The suggested method can be used to calculate the parameters of real GDL accurately without any modification.

• Tunnel and Underground Space
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• v.10 no.1
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• pp.45-58
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• 2000

Cyclic shear test system, which is capable of measuring flow rate inside rock joint, was established to investigate the hydraulic behavior of rough rock joints under various loading conditions. Laboratory hydraulic tests during compression and shear were conducted for artificial rough rock joints. Prior to tests, aperture characteristics of specimens were examined by measuring surface topography. Permeability changes under compression were well approximated with several hydraulic model. Hydraulic behavior conformed to dilation characteristics in the first stage, and permeability increased with increase of dilation. As the shear displacement progressed, flow rate became somewhat constant due to gouge production and offset of apertures. Hydraulic behavior under cyclic shear loading was also influenced by the degradation of asperities and gouge production. In addition. the relation between hydraulic aperture and mechanical aperture under compression and shear loading was investigated and compared.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1997.04a
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• pp.119-119
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• 1997

Valacyclovir is a L-valyl ester prodrug of acyclovir which is a highly effective and selective antiviral agent in the treatment of herpes virus diseases. Valacyclovir is rapidly and almost completely converted to acyclovir and increases the oral bioavailability of acyclovir three to five fold. However, the intestinal absorption mechanism of valacyclovir is not clear. If the improved absorption mechanism of valacyclovir is fully understood, it will provide a rationale of designing the amino acid ester prodrugs of polar drugs containing hydroxyl group. The main objective of our present study is to characterize the membrane transport mechanism of valacyclovir. Methods : Intestinal absorption of valacyclovir was investigated by using in-situ rat perfusion study and its wall permeability was estimated by modified boundary layer model. The membrane transport mechanism was also investigated through the uptake study in Caco-2 cells and in CHO-hPepTl cells. Results : In the rat perfusion study, the wall permeability of valacyclovir was ten times higher than acyclovir and showed concentration dependency, Valacyclovir also demonstrated a D,L stereo-selectivity with L-isomer having an approximately five-fold higher permeability than D-isomer. Mixed dipeptides and cephalexin, which are transported by dipeptide carriers, strongly competed with valacyclovir for the intestinal absorption, while L-valine did not show any competition with valacyclovir. This indicated that the intestinal absorption of valacyclovir could be dipeptide carrier-mediated. In addition, the competitive uptake study in Caco-2 cells presented that dipeptides reduced the valacyclovir uptake but valine did not. Also, in IC$\sub$50/ study, valacyclovir showed strong inhibition on the $^3$H-gly-sar uptake in CHO-hPepTl cells over-expressing a human intestinal peptide transporter. Taken together, the result from our present study indicated that valacyclovir utilized the peptide transporter for the intestinal absorption.

• Journal of Ginseng Research
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• v.37 no.1
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• pp.108-116
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• 2013

For the improvement of ginsenoside bioavailability, the ginsenosides of fermented red ginseng by Phellinus linteus (FRG) were examined with respect to bioavailability and physiological activity. The polyphenol content of FRG ($19.14{\pm}0.50$ mg/g) was significantly higher (p<0.05) compared with that of non-fermented red ginseng (NFRG, $11.31{\pm}1.15$ mg/g). The antioxidant activities in FRG, such as 2,2'-diphenyl-1-picrylhydrazyl, 2,2-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid, and ferric reducing antioxidant power, were significantly higher (p<0.05) than those in NFRG. The HPLC analysis results showed that the FRG had a high level of ginsenoside metabolites. The total ginsenoside contents in NFRG and FRG were $41.65{\pm}1.53$ mg/g and $50.12{\pm}1.43$ mg/g, respectively. However, FRG had a significantly higher content ($33.90{\pm}0.97$ mg/g) of ginsenoside metabolites (Rg3, Rg5, Rk1, compound K, Rh1, F2, and Rg2) compared with NFRG ($14.75{\pm}0.46$ mg/g). The skin permeability of FRG was higher than that of NFRG using Franz diffusion cell models. In particular, after 3 h, the skin permeability of FRG was significantly higher (p<0.05) than that of NFRG. Using a rat everted intestinal sac model, FRG showed a high transport level compared with NFRG after 1 h. FRG had dramatically improved bioavailability compared with NFRG as indicated by skin permeation and intestinal permeability. The significantly greater bioavailability of FRG may have been due to the transformation of its ginsenosides by fermentation to more easily absorbable forms (ginsenoside metabolites).

• Journal of Korean Society on Water Environment
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• v.28 no.2
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• pp.292-299
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• 2012

The objective of this study is to develop a novel method for evaluating forward osmosis (FO) membrane performances using a non-pressurized FO system. Basic membrane performance parameters including water (A) and solute (B) permeability coefficients and unique parameter for FO membrane such as the support layer structural parameter (S) were determined in two FO modes (i.e., active layer faces feed solution (AL-FS) and active layer faces draw solution (AL-DS)). Futhermore, these parameters were compared with those determined in a pressurized reverse osmosis (RO) system. Theoretical water flux was calculated by employing these parameters to a model that accounts for the effects of both internal and external concentration polarization. Water flux from FO experiment was compared to theoretical water fluxes for assessing the reliability of those parameters determined in three different operation modes (i.e., AL-FS FO, AL-DS FO, and RO modes). It is demonstrated that FO membrane performance parameters can be accurately measured in non-pressurized FO mode. Specifically, membrane performance parameters determined in AL-DS FO mode most accurately predict FO water flux. This implies that the evaluation of FO membrane performances should be performed in non-pressurized FO mode, which can prevent membrane compaction and/or defect and more precisely reflect FO operation conditions.