• The Journal of Engineering Geology
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• v.9 no.3
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• pp.187-206
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• 1999

A computer program to numerically predict the permeability tensor of fractured rocks is developed using information on discontinuities which Borehole Televiewer and Borehole Image Processing System (BIPS) provide. It uses orientation and thickness of a large number of discontinuities as input data, and calculates relative values of the 9 elements consisting of the permeability tensor by the formulation based on the EPM model, which regards a fractured rock as a homogeneous, anisotropic porous medium. In order to assess feasibility of the program on field sites, the numerically calculated tensor was obtained using BIPS logs and compared to the results of pumping test conducted in the boreholes of the study area. The degree of horizontal anisotropy and the direction of maximum horizontal permeability are 2.8 and $N77^{\circ}CE$, respectively, determined from the pumping test data, while 3.0 and $N63^{\circ}CE$ from the numerical analysis by the developed program. Disagreement between two analyses, especially for the principal direction of anisotropy, seems to be caused by problems in analyzing the pumping test data, in applicability of the EPM model and the cubic law, and in simplified relationship between the crack size and aperture. Aside from these problems, consideration of hydraulic parameters characterizing roughness of cracks and infilling materials seems to be required to improve feasibility of the proposed program. Three-dimensional assessment of its feasibility on field sites can be accomplished by conducting a series of cross-hole packer tests consisting of an injecting well and a monitoring well at close distance.

• Korean Journal of Radiology
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• v.22 no.1
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• pp.118-130
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• 2021

Objective: This study aimed to investigate the blood-brain barrier (BBB) disruption in mild traumatic brain injury (mTBI) patients with post-concussion syndrome (PCS) using dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging and automatic whole brain segmentation. Materials and Methods: Forty-two consecutive mTBI patients with PCS who had undergone post-traumatic MR imaging, including DCE MR imaging, between October 2016 and April 2018, and 29 controls with DCE MR imaging were included in this retrospective study. After performing three-dimensional T1-based brain segmentation with FreeSurfer software (Laboratory for Computational Neuroimaging), the mean K^trans and v_p from DCE MR imaging (derived using the Patlak model and extended Tofts and Kermode model) were analyzed in the bilateral cerebral/cerebellar cortex, bilateral cerebral/cerebellar white matter (WM), and brainstem. K^trans values of the mTBI patients and controls were calculated using both models to identify the model that better reflected the increased permeability owing to mTBI (tendency toward higher K^trans values in mTBI patients than in controls). The Mann-Whitney U test and Spearman rank correlation test were performed to compare the mean K^trans and v_p between the two groups and correlate K^trans and v_p with neuropsychological tests for mTBI patients. Results: Increased permeability owing to mTBI was observed in the Patlak model but not in the extended Tofts and Kermode model. In the Patlak model, the mean K^trans in the bilateral cerebral cortex was significantly higher in mTBI patients than in controls (p = 0.042). The mean v_p values in the bilateral cerebellar WM and brainstem were significantly lower in mTBI patients than in controls (p = 0.009 and p = 0.011, respectively). The mean K^trans of the bilateral cerebral cortex was significantly higher in patients with atypical performance in the auditory continuous performance test (commission errors) than in average or good performers (p = 0.041). Conclusion: BBB disruption, as reflected by the increased K^trans and decreased v_p values from the Patlak model, was observed throughout the bilateral cerebral cortex, bilateral cerebellar WM, and brainstem in mTBI patients with PCS.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.23 no.3
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• pp.108-114
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• 1997

The skin permeation study has two meanings in cosmetics. One is how to promote the skin permeation of active meterials for improving their bioavailabilities and the other is how to decrease it of irritants for reducing their skin side effects. In this study, we selected methyl paraben, one of the preservatives, as a model irritant and tried to reduce the skin irritation by the decrease of skin permeation. Furthermore, the relationship between skin permeation and skin primary irritation was discussed. For in vitro skin permeation experiments, Franz type diffusion cells and the excised skin of female hairless mouse from 8 weeks old were used. The donor compartment was charged with oil only or O/W emulsion containing 0.3% MP. We selected 19 oils, including esters, triglycerides, plant oils, hydrocarbons, and alchols, which are broadly used in cosmetics. We evaluated with female guinea pig. The skin permeahility of MP from the oils showed following order: ester oils > triglycerides > plant oils > hydrocarbons > alcohols. We considered that this result was based on the different effect of each oil on the barrier function of stratum corneum. In O/W emulsion containing each oil, the skin permeability of MP decreased as the oil/water partition coefficient of MP increased. The skin primary irritation increased as the skin permeability of MP increased. In conclusion, we suggest that the skin irritation could be reduced by the decrease of skin permeability of MP, which may be obtained by the good selection of oils in cosmetic preparations.

• Computers and Concrete
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• v.13 no.1
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• pp.17-30
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• 2014

This research presents the effect of various ground pozzolanic materials in blended cement concrete on the strength and chloride penetration resistance. An experimental investigation dealing with concrete incorporating ground fly ash (GFA), ground bottom ash (GBA) and ground rice husk ash (GRHA). The concretes were mixed by replacing each pozzolan to Ordinary Portland cement at levels of 0%, 10%, 20% and 40% by weight of binder. Three different water to cement ratios (0.35, 0.48 and 0.62) were used and type F superplasticizer was added to keep the required slump. Compressive strength and chloride permeability were determined at the ages of 28, 60, and 90 days. Furthermore, using this experimental database, linear and nonlinear multiple regression techniques were developed to construct a mathematical model of chloride permeability in concretes. Experimental results indicated that the incorporation of GFA, GBA and GRHA as a partial cement replacement significantly improved compressive strength and chloride penetration resistance. The chloride penetration of blended concrete continuously decreases with an increase in pozzolan content up to 40% of cement replacement and yields the highest reduction in the chloride permeability. Compressive strength of concretes incorporating with these pozzolans was obviously higher than those of the control concretes at all ages. In addition, the nonlinear technique gives a higher degree of accuracy than the linear regression based on statistical parameters and provides fairly reasonable absolute fraction of variance ($R^2$) of 0.974 and 0.960 for the charge passed and chloride penetration depth, respectively.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.03a
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• pp.338-350
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• 2010

As existing materials for ground reinforcement, chemical grout material using cementitous materials and waterglass was used. But many problems in terms of ground reinforcement effects were implicated. In this study, for development and applicability verification of new materials, viscosity, fluidity, permeability, Self-Leveling, keeping of drilled hole, antiwashout underwater, resistance of water (groundwater dilution and minimize material eluting) and the early strength and long-term strength characteristics of developed materials was confirmed, and material standards, and establishing construction standards for the various model tests were conducted. As a result, high viscosity, flowability, permeability and keeping of drilled hole characteristics are excellent, in addition to the early strength properties, dilution does nat occur to groundwater, including groundwater is available for dealing with environmental issues. Application of basic and reinforcement method by Filler function in addition to structure can also or development of a new concept can be expected. In addition, middle and large-diameter drilled shaft, micropile, ground anchors, soil-nailing, steel pipes multi-grouting reinforcement for cement injection process could be used enough to even be considered.

• Proceedings of the KIEE Conference
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• 1994.07a
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• pp.147-149
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• 1994

In designing high efficiency electrical machines, calculation of iron loss is very important. And it is reported that in the induction motor and in the T-joint of 3 phase transformer, there occurred rotational magnetic field and much iron loss is generated owing to this field. In this paper, rotational power loss in the electrical machine under rotational magnetic field is discussed. Until now, loss analysis is based on the magnetic properties under alternating field. And with this one dimensional magnetic propertis, it is difficult to express iron loss under rotational field. In this paper, we used two dimensional magnetic property data for the numerical calculation of rotational power loss. We used finite element method for calculation and the analysis model is two dimensional magnetic property measurement system. We used permeability tensor instead of scalar permeability to present two dimensional magnetic properties. And in this case, we cannot uniquely define energy functional because of the asymmetry of the permeability tensor, so Galerkin method is used for finite element analysis.

• Geomechanics and Engineering
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• v.7 no.1
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• pp.105-131
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• 2014

In this paper, the effects of variability of smear zone characteristics induced by installation of prefabricated vertical drains on the preloading design are investigated employing analytical and numerical approaches. Conventional radial consolidation theory has been adopted to conduct analytical parametric studies considering variations of smear zone permeability and extent. FLAC 2D finite difference software has been employed to conduct the numerical simulations. The finite difference analyses have been verified using three case studies including two embankments and a large-scale laboratory consolidometer with a central geosynthetic vertical drain. A comprehensive numerical parametric study is conducted to investigate the influence of smear zone permeability and extent on the model predictions. Furthermore, the construction of the trial embankment is recommended as a reliable solution to estimate accurate smear zone properties and minimise the post construction settlement. A back-calculation procedure is employed to determine the minimum required waiting time after construction of the trial embankment to predict the smear zone characteristics precisely. Results of this study indicate that the accurate smear zone permeability and extent can be back-calculated when 30% degree of consolidation is obtained after construction of the trial embankment.

• YAKHAK HOEJI
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• v.51 no.1
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• pp.1-6
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• 2007

The aim of this study was to examine whether administration of glutamine are able to prevent the methotrexate induced gut barrier damage, bacterial translocation, and weight changes. The animals with glutamine were fed with L-glutamine (1.2 and 2.4 mg/kg/day) for 7 days before methotrexate administration (20 mg/kg orally). 48 hour after methotrexate administration, intestinal permeability were measured for an assessment of the gut barrier dysfunction. Also, enteric aerobic bacterial counts, number of gram-negatives in mesenteric lymph node (MLN), liver spleen, kidney and heart were measured for an assessment of the enteric bacterial number and bacterial translocation. Amounts of food intake, body weight changes and organ weight changes of liver spleen, kidney and heart were measured. Methotrexate administration caused body and liver weight loss regardless amounts of food intakes. Methotrexate induced increasing intestinal permeability, enteric bacterial undergrowth and bacterial translocation to MLN, liver and spleen, but not kidney and heart. The supplements with glutamine reduced the intestinal permeability bacterial translocation, and not influences enteric bacterial number, and body and liver weight changes. This study suggested that glutamine might effectively reduce methotrexate induced intestinal damage and bacterial translocation, but not influence body and organ weight loss.

• Journal of the Korean GEO-environmental Society
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• v.2 no.1
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• pp.81-89
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• 2001

Soil-bentonite mixture is often used for barrier wall to prevent seawater intrusion. In this study, the effect of seawater on the permeability of soil-bentonite mixture is examined, and the effect of permeability change on the seawater intrusion is investigated. Seawater intrusion in coastal areas was modeled using a finite element method. Seawater intrusion in the seawater-contaminated zone was determined by considering the hydraulic conductivity changes using the residual flow procedure (RFP) in the simulation model. Steady state and unsteady state conditions with variations in ground water levels in an inland area were investigated. The interface between fresh water and seawater, found by the proposed method, was located lower at the seawater side and the level at the fresh water side is higher than those by conventional methods.

• Journal of the Korean Society for Precision Engineering
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• v.18 no.12
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• pp.73-81
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• 2001

The MIAB welding uses a rotating arc as its heat source and is known as an efficient method fur pipe butt welding. The arc is rotated around the weld line by the electro-magnetic force resulting from the interaction of arc current and magnetic field. The electro-magnetic force is affected by magnetic flux density, arc current, and arc length. Especially, the magnetic flux density is an important factor on arc rotation and weld quality. This paper presents a 2D finite element model for the analysis of magnetic flux density in the actual welding conditions. The magnetic flux density is mainly dependent on gap between two pipes, the position of coil from gap center, exciting current, and relative permeability. Thus, the relations between magnetic flux density and main factors were investigated through experiment and analysis. Experiments were performed for the steel pipes(48.1mm O.D and 2.0mm thickness). The analysis results of magnetic flux density reveal that it increases with increasing exciting current, increasing relative permeability, decreasing distance from gap center to coil, and decreasing gap size. It is considered that the results of this study can be used as important data on the design of coil system and MIAB welding system.