• 대한수의학회지
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• 제54권1호
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• pp.7-12
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• 2014

Peripheral nerve sheath tumors (PNSTs) are heterogeneous tumor groups of peripheral nerves that originate from either Schwann cells or modified Schwann cells, fibroblasts, or perineural cells. In this study, signalment and clinical data such as tumor location and size were evaluated for 15 cases of PNSTs collected from local animal hospitals. The mean age of dogs with malignant PNST was higher than that of dogs with benign PNST. Additionally, the male to female ratio in dogs with PNST was 1 : 4. In dogs with PNST, the primary sites of involvement were the hindlimb, forelimb, around the mammary glands, the neck, and the abdomen. Histiopathologic examination revealed that eight PNSTs were benign and seven were malignant. The tumor cells were composed of loosely to densely arranged interlacing bundles and wavy spindle cells arranged in short bundles, palisading, and whirling. High mitotic figures, local invasion, multifocal necrosis and atypical multinucleated giant cells were observed in malignant PNST cases. All PNSTs showed immunoreactivity for vimentin and S-100. However, only 93.3% and 73.3% were immunoreactive for NSE and GFAP, respectively. Overall, these results indicated that immunohistochemical markers such as vimentin, S-100 and NSE could help confirm the diagnosis of canine PNSTs.

• Archives of Plastic Surgery
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• 제34권4호
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• pp.495-497
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• 2007

Purpose: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms, usually arising from somatic soft tissues or peripheral nerves. Primary MPNST of the scalp is extremely rare. The case is being reported for its rarity. Methods: A 53-year-old female was presented with a scalp mass on vertex area. The tumor was localized in scalp skin and did not invade underlying periosteum or skull and treated with complete surgical excision followed by adjuvant chemotherapy and radiotherapy. Results: Histologically, the tumor showed malignant spindle cells with focal S-100 positivity on immunohistochemistry and a diagnosis of MPNST was made. Conclusion: Authors experienced a rare case of primary scalp MPNST and report the case.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제34권1호
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• pp.76-80
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• 2012

Adenoid cystic carcinoma is a distinctive neoplasm of the salivary gland and is the most common malignant tumor of submandibular gland. Although adenoid cystic carcinoma grows slowly, it shows aggressive tendencies with the ability to invade peripheral nerves. This ability enables an adenoid cystic carcinoma to extend along the nerves and spread long distances, resulting in high incidence of distant metastasis and recurrence. Therefore, radical resection is the treatment of choice for this carcinoma. We performed partial mandibulectomy, neck dissection and immediate reconstruction using a radial forearm free flap on a 54 year-old man with adenoid cystic carcinoma on the right submandibular gland. And as an adjunctive therapy, chemotherapy with cisplatin and 5-fluorouracil was used. We report our case along with a literature review.

• 척추신경추나의학회지
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• 제6권1호
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• pp.89-96
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• 2011

Objective : The purpose of this study is to evaluate the korean medical treatment for compressive neuropathy of radial nerve, especially chuna treatment of cervical vertebrae. Methods : Two patients were treated with acupuncture and moxibustion, herbal medication, chuna treatment on cervical vertebrae. To evaluate the wrist drop and numbness of hand, Coding Result of arbitrary values and manual muscle test(MMT), visual analogue scale(VAS) were used. Results : After 2 weeks-treatment(in case 1) & 5 weeks-treatment(in case 2), the movement and power of wrist were restored to nearly normal range, also the numbness of hands was removed. All cases show the improvement in the movement of wrist and the numbness of hands. Conclusions : Korean medical treatment including cervical manual therapy as chuna treatment is remarkably effective for radial nerve palsy. But further studies are required to concretely prove the effectiveness of chuna treatment on central vertebrae for peripheral neuropathy.

• Annals of Clinical Neurophysiology
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• 제22권1호
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• pp.37-40
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• 2020

Neurolymphomatosis (NL) is characterized by the infiltration of malignant lymphoma cells into peripheral nerves, nerve roots, plexuses, or cranial nerves. This is a very rare complication of mantle-cell lymphoma. Diagnosing NL is made difficult by cerebrospinal fluid cytology and bone-marrow biopsy results often being negative. NL can appear as the only sign of recurrence in a patient with a previous diagnosis of lymphoma. Here we present two cases of NL in patients with mantle-cell lymphoma diagnosed by positron emission tomography with deoxy-fluoro-D-glucose integrated with computed tomography.

• 한방안이비인후피부과학회지
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• 제10권1호
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• pp.349-356
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• 1997

an acute, unilateral, self-limited inflammatory disease of cerebral ganglia and the ganglia of posterior nerve roots and peripheral nerves in a segmented distribution, caused by the chickenpox virus, and characterized by groups of small vesicles in the cutaneous areas along the course of affected nerves, and associated with neuralgic pain. three case of herpes zoster has severe post herpetic neuralgia. these patients has been treated with westernmedicine. But they could not expect to improve condition. We exprienced three cases of herpes zoster that have a result of effect with oriental treatment and lazer threaphy.

• 대한수의학회지
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• 제44권4호
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• pp.483-486
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• 2004

The expression of nestin and vimentin in the spinal nerve roots of rats with experimental autoimmune encephalomyelitis (EAE) was studied to ascertain whether Schwann cells in the peripheral nerves respond to acute central nervous system autoimmune injury. Immunohistochemistry demonstrated that nestin was constitutively expressed in the dorsal roots of spinal nerves in control rats; its expression was enhanced in the spinal nerve roots of rats with EAE. Vimentin expression was weak in control rat spinal nerve roots, and it was increased in the dorsal roots of rats with EAE. It is postulated that normal animals have multipotent progenitor cells that constitutively express nestin and vimentin in the spinal nerve roots. In response to an injury of the central nervous system, these multipotent Schwann cells are activated in the spinal nerve roots through the expression of the intermediate filament proteins vimentin and nestin.

• Journal of Chest Surgery
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• 제54권6호
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• pp.535-538
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• 2021

Schwannomas are rare benign tumors that develop in Schwann cells lining peripheral nerves. Schwannomas of the brachial plexus are especially rare, accounting for 5% of all cases. Although several treatments can be considered, the exact method of treatment is unclear owing to the scarcity and sporadic occurrence of schwannomas. Tumor resection is performed in most cases, and nerve damage is inevitable in cases of neuroinvasive schwannoma. In this case series, we present our successful use of transposition of cable-grafted nerves for the treatment of schwannomas. We performed cable-grafted nerve interposition in addition to tumor resection, leading to increased recovery of nerve damage. To relieve postoperative symptoms and minimize sequelae, precise surgical tumor resection followed by nerve interposition using a cable-grafted nerve may be recommended.

• Journal of Chest Surgery
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• 제20권3호
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• pp.439-450
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• 1987

The arterial blood pressure response elicited by stimulating the peripheral afferent fibers of different groups and origins was studied in cats. Experimental animals were anesthetized with a-chloralose [60mg/kg] and artificially ventilated with a respirator. The lumbosacral spinal cord was exposed through a laminectomy and L7 ventral root was isolated. The sural, medial gastrocnemius and common peroneal nerves were also exposed in the hindlimb. The arterial blood pressure was monitored continuously while the exposed peripheral nerves and L7 ventral root were being stimulated. Then, spinal lesions were made on the dorsolateral sulcus area, dorsolateral funiculus and other areas at the thoracolumbar junction. The arterial blood pressure responses were compared before and after making spinal lesions. The following results were obtained. 1. The mean arterial blood pressure was elevated from 103*7.3 to 129*8, 1 [mean*S.E.] mmHg [p<0.001] during stimulation of the sural nerve with C-strength [1000T], 20Hz. Stimulation with Ad-strength, 1Hz resulted in the depression of the arterial pressure by 8 mmHg [p<0.01]. 2. Stimulation of the medial gastrocnemius nerve with Ad-strength did not elicit any significant change in arterial blood pressure. Stimulation with C-strength, 20 Hz induced a pressor response from 102*6.2 to 117*6.4 mmHg [p<0.01] while that with C-strength, 1Hz induced a depressor response from 104*6.1 to 93*4.9 mmHg [p<0.001]. 3. A pressor response by 56 [from 107*7 5 to 163*9.4] mmHg [p<0.001] was induced during stimulation of the common peroneal nerve with C-strength, 20Hz stimuli. Stimulation with A4-strength, 1Hz depressed the arterial blood pressure from 111~9.3 to 94*7.8 mmHg [P<0.005]. The activation of the ventral root afferent fibers with C-strength, 20 Hz stimuli induced a pressor response by 22 mmHg [from 115*9.4 to 137*8.6 mmHg] [p<0.001]. 4. The pressor response elicited during stimulation of the sural nerve was abolished by making lesions on the dorsolateral sulcus area bilaterally. With the medial gastrocnemius nerve, the pressor response had not been abolished completely by the dorsolateral sulcus lesions. The pressor response disappeared completely with addition of the bilateral dorsolateral funiculus lesions. 5. The depressor response induced by stimulation of the sciatic nerve with Ad-strength, 1Hz was decreased by making lesions on the dorsolateral funiculus. 6. From the above results it is concluded that the difference in the blood pressure responses to the activation of the muscular afferent and the cutaneous afferent fibers is responsible for the groups of afferent fibers and the spinal ascending pathways.

• 한국응용곤충학회지
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• 제30권1호
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• pp.29-36
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• 1991

애반닷불이 (Luciola lateraιs Mot.) 성충과 유충 발광기관의 현미경 관찰결과와 발광기관과 신경계의 관계는 다음파 같다. 유충의 발광기관은 복부 8번째 마디 좌우 등쪽 측면에 한 쌍이 존재하였으며 복부 8번째 신경 절로부터 나온 한쌍의 말초신경에 지배받는다. 발광기관의 모양은 구형 혹은 구형과 유사한 형태이며 발광기관 주변에는 과립들이 있었다. 이러한 과립들은 유충령기가 높아갈수록 많아져 용화하기 위하여 지상에 상륙한 유충의 경우, 하나의 층을 형성하고 있는 것처럼 보였다. 그리고 발광기관에는 근육이 존재하며 기관과 기관소지도 발견되었다. 성층의 발광기관은 수컷의 경우 복부 5, 6째 마디에 있으며 암컷의 경우는 5째마디에만 존재했다. 성충의 발광기관은 발광세포 충(약 70$\mu m$의 두께)과 반사충(약 40$\mu m$의 두께)으로 구성되어 있었다. 그리고 유충의 발광기관 에서는 볼 수 없었던 기관지소기관(tracheal end organ)이 존재하였다. 복부 5째 마디의 발광기관 은 복합신경절 (유층의 6째, 7째,8째 복부마디의 신경절들이 융합된) 앞쪽에서 나온 두 쌍의 말 초신경에 의해 지배되며, 복부 6째 마디(수컷)의 발광기관은 복합신경절의 뒤쪽에서 나온 한쌍 의 말초신경에 지배받는다.