• Korean Journal of Clinical Laboratory Science
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• v.43 no.2
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• pp.57-67
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• 2011

In this study, we investigated the correlation between the administration of various antiviral agents and the alternation of specific biomarkers induced by the hepatitis B virus (HBV). Eligible subjects diagnosed with chronic hepatitis B were prescribed with antiviral drugs at the Gastroenterology Internal Medicine Department of E University Hospital in Daejeon between May 2004 and September 2009. Lamivudine was prescribed to 66 out of 100 patients. Of the 12 patients, 6 (50.0%) showed a change from being HBe-antigen-positive to being HBe-antigen-negative. Of the 39 patients, 23 (59.0%) showed higher than 40 IU/L alanine aminotransferase (ALT). Of the 65 patients, 41 (63.1%) showed HBV DNA decrease of 1 log, and were prescribed with Lamivudine. Adefovir was prescribed to 3 out of 100 patients. Of the 12 patients, 1 (8.3%) showed a change from being HBe-antigen-positive to being HBe-antigen-negative, and was prescribed with Adefovir. Entecavir was prescribed to 19 (19.0%) out of 100 patients. Of the 12 patients, 3 (25.0%) showed a change from being HBe-antigen-positive to being HBe-antigen-negative. Of the 12 patients, 3 (125.8%) showed higher than 40 IU/L ALT. Of the 65 patients, 14 (21.5%) showed HBV DNA decrease of 1 log, and were prescribed with Entecavir. Clavudine was prescribed to 7 out of 100 patients. Of the 12 patients, 1 (8.3%) showed a change from positive HBe antigen to negative HBe antigen. Of the 39 patients, 5 (12.8%) showed higher than 40 IU/L ALT. Of the 65 patients, 6 (9.2%) showed HBV decrease of 1 log, and were prescribed with Clavudine. These results do not show a statistically significant correlation between drugs and biomarkers. Data on combination therapy using Lamivudine and Adefovir show no statistically significant difference between drugs and biomarkers. Medications for periodic inspection was not correlated to HBe-antigen-negative conversion, ALT, and HBV DNA. HBV DNA was significantly reduced in patients with high levels of AST(aspartic acid aminotransferase) and ALT before treatment. In addition, the decrease of HBV DNA after 12 months of treatment was less frequently observed in patients treated with Lamivudine compared with other drugs. This result is associated with Lamivudine resistance. Although the association of drugs with diagnostic markers and the correct choice of treatment is difficult to determine, these results may be useful for further research on diagnosis and treatment of the hepatitis B virus.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.8
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• pp.183-192
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• 2018

The purpose of this study was to compare female nursing college students with respect to drinking habit, drinking motives, and drinking problems. (Ed note: confirm edited version; original is a bit unclear in intent) Subjects include nursing college students in some areas, and data were collected between April and May, 2018. A total of 181 questionnaires were analyzed. The frequency analysis was used to examine the differences between the normal and drinking-problem groups. Pearson's correlation analysis was used to examine the correlations of drinking problems, and logistic regression analysis was used to analyze the factors related to drinking problems. The findings show that the frequency of drinking, rate of drinking, drinking motives, life stress, and prior experiences with drinking problems recorded a high risk ratio for drinking problems. Specifically, the group with a drinking frequency of 2~3 times per week showed a risk ratio that was 21.53 times higher than the group with a drinking frequency of 1~4 times per year. The group of higher drinking motives recorded a risk ratio that was 5.96 times higher than the group of lower drinking motives. The group of higher experiences with drinking problems showed a risk ratio that was 8.80 times higher than the group of lower experiences with drinking problems. In conclusion, the frequency of drinking, rate of drinking, drinking motives, life stress, and experiences with drinking problems were factors highly related to the drinking problems in female college students. The results highlight that careful evaluation of drinking habit of college students are needed. Moreover, periodic temperance education and programs designed to identify and prevent drinking problems are necessary to lower the risk of developing drinking problems and promote a safe drinking culture.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.11
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• pp.332-339
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• 2016

This study aimed to investigate the awareness and performance of safety in operating room nurses. There were 161 operating room nurses from eight general hospitals included for analysis in this study. The data were analyzed with t-test, one-way ANOVA, correlation analysis, and Scheffe's test. The results show that their perception of patient safety was 3.33 out of a total of 5 points. Moreover, the score of safety management activity for patients in the operating room was 4.28 out of 5 points. As the perception of patient safety in operating room nurses was significantly correlated with their safety management activities, nurses with higher awareness of patient safety were found to have higher degree of performance of safety management activities. In conclusion, to improve safety management activities, open discussion about patient safety should be encouraged and periodic education regarding patient safety should be implemented for operating room nurses to increase the perception of patient safety.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.44 no.3 s.357
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• pp.33-40
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• 2007

In this paper, low-rate TCP attack as one of shrew attacks is considered and the scaling based dynamic time warping (S-DTW) algorithm is introduced. The low-rate TCP attack can not be detected by the detection method for the previous flooding DoS/DDoS (Denial of Service/Distirbuted Denial of Service) attacks due to its low average traffic rate. It, however, is a periodic short burst that exploits the homogeneity of the minimum retransmission timeout (RTO) of TCP flows and then some pattern matching mechanisms have been proposed to detect it among legitimate input flows. A DTW mechanism as one of detection approaches has proposed to detect attack input stream consisting of many legitimate or attack flows, and shown a depending method as well. This approach, however, has a problem that legitimate input stream may be caught as an attack one. In addition, it is difficult to decide a threshold for separation between the legitimate and the malicious. Thus, the causes of this problem are analyzed through simulation and the scaling by maximum auto-correlation value is executed before computing the DTW. We also discuss the results on applying various scaling approaches and using standard deviation of input streams monitored.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.4
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• pp.460-466
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• 2004

This study was undertaken with the aim to establish a reliable radioimmunoassay (RIA) system for urinary pregnanediol glucuronide (PdG) and to employ it for monitoring the reproductive status of dairy cows. Urine and blood samples were collected from the Holstein cows both pregnant and non-pregnant. The samples were then investigated for evaluating the relationship between progesterone ($P_{4}$) in blood and PdG in urine adjusted with or without urinary creatinine basis. Biweekly urine collection was employed for three cows in estrous and those artificially inseminated, while urine from pregnant cows was collected on a monthly basis. P_{4}$ and PdG levels were measured by enzymeimmunoassay (EIA) and RIA techniques, respectively. Our results indicated the sensitivity of PdG for RIA being 35 pg/tube and the recovery rate of 100%. Urinary creatinine concentrations also fluctuated within a day, but change at midday was not noteworthy. Regardless of the time of urination the change in concentrations of PdG was relatively smaller and did not vary significantly. The urinary PdG concentration showed periodic changes as that with serum P_{4}$ levels during the cow's estrus cycle. The correlation coefficient rose when creatinine level in urine was adjusted but the change was also not significant. The concentrations of PdG during the luteal phase were detected between 8.2 and 17.4 ng/ml, three to five times higher than that in the follicular phase. The concentration of PdG from pregnant cows (21 days after conception) was three to four times higher than in the nonpregnant cows. Our finding suggests that the determination of urinary PdG could be reliably employed for early pregnancy detection. The urinary PdG level continued to raise until 30 days pre-partum while the concentration reached its peak at 30 ng/ml, after which it started to fall 18 to 30 days before parturition and finally fell to its nadir value one week after parturition. As the correlation coefficient between the urinary PdG and serum P_{4}$ was higher than that corrected by urinary creatinine it can be suggested that the adjustment is not needed. The concentrations of urinary PdG could be maintained stably for 2 days in urine samples stored at room temperature and extended to 8 days when the samples were pretreated by boiling for 30 minutes. In conclusion urinary PdG concentration even without the need for creatinine basis adjustment can be used directly for monitoring the reproductive status of dairy cows.

• Journal of Korean Foot and Ankle Society
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• v.22 no.1
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• pp.21-25
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• 2018

Purpose: To analyze the correlation between a rupture of the hypovascular zone and early single heel raising after Achilles tendon repair. Materials and Methods: From January 2012 to August 2015, 68 patients, who underwent surgical treatment for a Achilles tendon rupture using Krackow method, were analyzed retrospectively. The patients were divided into two groups according to possibility of single heel raises within 3 months postoperatively. During the periodic outpatient observations, the visual analogue scale, Achilles tendon total rupture score (ATRS), and timing capable single heel raises were evaluated. In addition, the preoperative defect size and distance between the calcaneal osteotendinous junction and the rupture site were measured by ultrasound in all cases. Results: Twenty-three patients could perform a single heel raise within 3 months after surgery (early single heel raise group), and fortyfive patients could perform a single heel raise after 3 month postoperatively. The age, gender, body mass index, smoking, and operation delay were similar in the two groups. In addition, the defect size and distance between the calcaneal osteotendinous junction and rupture site as measured by preoperative ultrasound were similar (p=0.379 and p=0.631, respectively). On the other hand, when the rupture site was divided into the hypovascular zone (4~7 cm from calcaneal osteotendinous junction) and non-hypovascular zone, the hypovascular zone rupture rate was significantly lower in the early single heel raise group (60.9%, 14/23; 91.1%, 41/45; p=0.003). In logistic regression analysis, the odds of the hypovascular zone rupture group being capable of early single heel raise were 0.189 (p=0.017). The ATRS score at 3 months and 1 year after surgery were significantly higher in the early single heel raise group (p<0.001). Conclusion: Achilles tendon rupture at the hypovascular zone is a poor prognostic factor for early single heel raise and might affect the prognosis significantly after an Achilles tendon rupture operation.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.24 no.10
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• pp.987-993
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• 2013

Chaos communication system has characteristics of non-periodic, non-predictability, broadband signal and easy implementation. Also, chaos communication system is sensitive to the initial value, because completely another signal is generated when initial value of chaos equation is changed subtly. By these characteristics, security of chaos communication system is generally evaluated better than other digital communication systems. However, BER(Bit Error Rate) performance is worse than other digital communication systems, because transmitter and receiver of existing chaos communication system are strongly influenced by reference signal and noise. So, studies in order to improve the BER performance of chaos communication system is continuously performed. In this paper, We will propose a new CDSK (Correlation Delay Shift Keying) receiver in order to improve the BER performance. After we compare to the performance of existing receiver and proposed receiver, BER performance of proposed receiver evaluate. A novel receiver has characteristic that BER performance is better than existing receiver. However, if existing transmitter is used, existing receiver is possible to recover information bits even though BER performance is bad. Therefore, we propose a novel CDSK transmitter in order to improve the security of proposed receiver. When information bits are transmitted by using proposed transmitter, existing receiver is impossible to recover information bits, and proposed receiver is possible to recover information bits.

• Journal of the korean academy of Pediatric Dentistry
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• v.40 no.2
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• pp.106-117
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• 2013

Normal eruption of the canine is important for the transition to the permanent dentition. Etiologies, including premature loss or delayed retention of deciduous teeth, neoplasm and abnormality of lateral incisor can cause impaction of the maxillary canine. Untreated canine impaction can result in malocclusion, cyst formation and obstacles in orthodontic treatment. The aim of this study is to evaluate location of the impacted maxillary canine and to identify correlation between location and management of the impaction including complications. Using panoramic radiographs and CBCT scan, images of 89 children diagnosed with impaction of the maxillary canine, location of impacted canines was evaluated. The choice of treatment and complications were investigated to identify correlation. Results show that the most commonly impacted location of the maxillary canine was in the mid-alveolar area, followed by buccal side and palatal side. Orthodontic traction was selected more frequently than the other treatments. As complications, displacement of adjacent tooth was occurred most frequently. Buccally impacted canines showed increased tendency towards displacement. The more buccally the canine was impacted, the less orthodontic traction was chosen as the treatment. The canine impacted mesially to the central incisor showed increased tendency to occur root resorption. Therefore, early diagnosis by periodic examination, appropriate treatment and intervention is required.

• Weed & Turfgrass Science
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• v.1 no.4
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• pp.24-30
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• 2012

This study was conducted to select the cover crops in organic apple orchard by estimating the coverage of each cover crops and time-periodic weed occurrence. Seeding of Festuca myuros and Trifolium repens showed high contents of soil organic matter and phosphorus as compared with control. Seeding of Trifolium sp., Hordeum vulgare and Secale cereal reduced relatively occurrence of weed in May and S. cereal among others showed the greatest effect in June. In July, seeding F. arundinaceae and Poa pratensis showed low coverage and a lot of weeds occurred in their field. Fifty one species were occurred as weeds and it needs to removal of high and broadleaf weeds such as Chenopodium ficifolium, C. album var. centrorubru and Humulus japonicus in spring to increase the rate of ground cover. P. pratensis having the lowest cover rate showed the similar dry weight of weeds as compared with control. Trifolium sp. and Persicaria hydropiper had a high correlation with contents of soil organic matter and C. album var. centrorubru had a correlation with contents of soil phosphorus by CCA analysis.

• The Journal of the Convergence on Culture Technology
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• v.10 no.1
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• pp.585-590
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• 2024

In this study, rail surface defects are increasing due to the aging of urban railway rails, but in the detailed guidelines for track performance evaluation established by the country, rail surface damage is inspected with the naked eye of engineers and simple measuring tools. With the recent enactment of the Track Diagnosis Act, a large budget has been invested and the volume of rail diagnosis is rapidly increasing, but it is difficult to secure the reliability of diagnosis results using labor-intensive visual inspection techniques. It is very important to discover defects in the rail surface through periodic track tours and visual inspection. However, evaluating the severity of defects on the rail surface based on the subjective judgment of the inspector has significant limitations in predicting damage inside the rail. In this study, the rail internal crack characteristics due to rail surface damage were studied. In field measurements, rail surface damage locations were selected, samples of various damage types were collected, and the rail surface damage status was evaluated. In indoor testing, we intend to analyze the correlation between rail surface defects and internal defects using a electron scanning microscope (SEM). To determine the crack growth rate of urban railway rails currently in use, the Gaussian probability density function was applied and analyzed.