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Breast Cancer Trend in Iran from 2000 to 2009 and Prediction till 2020 using a Trend Analysis Method

  • Zahmatkesh, Bibihajar;Keramat, Afsaneh;Alavi, Nasrinossadat;Khosravi, Ahmad;Kousha, Ahmad;Motlagh, Ali Ghanbari;Darman, Mahboobeh;Partovipour, Elham;Chaman, Reza
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.3
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    • pp.1493-1498
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    • 2016
  • Background: Breast cancer is the most common cancer in women worldwide with a rising incidence rate in most countries. Considering the increase in life expectancy and change in lifestyle of Iranian women, this study investigated the age-adjusted trend of breast cancer incidence during 2000-2009 and predicted its incidence to 2020. Materials and Methods: The 1997 and 2006 census results were used for the projection of female population by age through the cohort-component method over the studied years. Data from the Iranian cancer registration system were used to calculate the annual incidence rate of breast cancer. The age-adjusted incidence rate was then calculated using the WHO standard population distribution. The five-year-age-specific incidence rates were also obtained for each year and future incidence was determined using the trend analysis method. Annual percentage change (APC) was calculated through the joinpoint regression method. Results: The bias adjusted incidence rate of breast cancer increased from 16.7 per 100,000 women in 2000 to 33.6 per 100,000 women in 2009. The incidence of breast cancer had a growing trend in almost all age groups above 30 years over the studied years. In this period, the age groups of 45-65 years had the highest incidence. Investigation into the joinpoint curve showed that the curve had a steep slope with an APC of 23.4% before the first joinpoint, but became milder after this. From 2005 to 2009, the APC was calculated as 2.7%, through which the incidence of breast cancer in 2020 was predicted as 63.0 per 100,000 women. Conclusions: The age-adjusted incidence rate of breast cancer continues to increas in Iranian women. It is predicted that this trend will continue until 2020. Therefore, it seems necessary to prioritize the prevention, control and care for breast cancer in Iran.

Histological Observation on the Seasonal Changes of Distribution of Muscle Components in Hibernant Fish - 2. Distributional Changes of Carbohydrate, Protein and Lipid Components in the Muscle Tissues of Mudskipper, Boleophthalmus pectinirostris (동면 어류의 시기별 근육성분 분포에 관한 조직학적 관찰 - 2. 짱뚱어(Boleophthalmus pectinirostris) 근육조직중 탄수화물, 단백질 및 지방질 분포의 변화)

  • Park, Il-Woong;Hong, Jai-Sik;Lee, Keun-Kwang;Kim, Jong-Bae;Kang, Kui-Hwan;Kim, Hyun-Ouk
    • Korean Journal of Ichthyology
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    • v.7 no.2
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    • pp.195-202
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    • 1995
  • The seasonal changes in the muscle components of hibernant fish, amphibious mudskipper (Boleopthalmus pectinirostris), caught during the period between June 1993 and April 1994 were studied. The distributional changes of its major components in each muscle tissues was also observed before and after spawning and hibernation. Moisture content was the lowest after spawnig season and the highest just after hibernation, but crude protein was the highest after spawning sea-son. Crude lipid in female was the highest before spawning season, while in male it was the highest after spawning season, but both of female and male the lowest just after hibernation. Carbohydrate content in female and male showed the highest value just before hibernation and tended to decrease thereafter. In case of mudskipper, dyeing distribution was more or less spread in almost all of the tissues after spawning season but showed nearly no difference just after hibernation with the exception of small increase in dyeing degree of muco layer and epidermis layer. Investigation of mudskipper muscle tissue through the method of sudan black B dyeing yielded the results as follows ; lipid component in mudskipper in seasons before and after spawning season was percieved as mainly distributed in muco layer, epidermis and hypodermis layer respectively and also percieved a little between hypodermis subscutoneus cells. In season just before hibernation, it prevailed in almost all of the tissues, contrary to the weakness in its distribution degree just after hibernation.

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Quality Characteristics of Press Ham Containing Conjugated Linoleic Acid-Triglyceride (Conjugated linoleic acid-triglyceride가 함유된 프레스햄 품질특성)

  • Lee, Jeong-Ill;Joo, Y.K.;Kang, G.H.;Yang, H.S.;Jeong, J.Y.;Joo, S.T.;Park, G.B.
    • Journal of Animal Science and Technology
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    • v.49 no.1
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    • pp.109-120
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    • 2007
  • CLA was chemically synthesized by alkaline isomerization method using corn oil. CLA-TG was synthesized by chemical reaction using sodium methoxide. For the control, 10% of back fat among the total component was only added without the annex of CLA-TG. For the first treatment, 5% of CLA-TG among the lard component added into the press ham was replaced. For the 2nd, 3rd and 4rd treatments, 10%, 15% and 20% of CLA-TG was respectively replaced. Manufacture press ham using CLA-TG were vacuum packaged and then stored during 1, 7, 14, 21 and 28 days at 4℃. Samples were analyzed for shear force value, sensory evaluation, TBARS, fatty acid composition and CLA content. Shear force value of control was significantly higher than that of CLA-TG treatment groups(P<0.05). All treatments were increased by the passage of storage time. No remarkable differences were found in sensory properties among control and CLA-TG treatment groups. CLA-TG treatment groups showed significantly(P<0.05) lower TBARS value than the control. TBARS value was increased significantly during storage in all treatment. In the change of fatty acid composition, the contents of C14:0~C20:4 were decreased significantly by CLA-TG additive. Whereas the increase level of CLA-TG additive resulted in the significantly higher unsaturated fatty acid and CLA content. Summing up the a forementioned results, press ham manufacturing with CLA-TG additive was not affected in sensory evaluation. Also, it may be assumed that the high quality press ham can be manufactured with the extent of storage period and CLA accumulation.

Temporal and Spatial Variations of Water Quality in the Cheonsu Bay of Yellow Sea, Korea (천수만 수질환경의 시·공간적 변동특성)

  • Park, Soung-Yun;Heo, Seung;Yu, Jun;Hwang, Un-Ki;Park, Jong-Su;Lee, Sung-Min;Kim, Chang-Mi
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.19 no.5
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    • pp.439-458
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    • 2013
  • Temporal and spatial variations of water quality were investigated in the Cheonsu Bay of Yellow Sea, Korea from 2010 to 2011. Water samples were collected at 16 stations and physicochemical parameters were analyzed including water temperature, salinity, suspended solids (SS), chemical oxygen demand (COD), dissolved oxygen (DO), Chlorophyll a and nutrients. Spatial distribution patterns of all survey items were not clear among stations but the bimonthly variations were distinct except the bottom water of the suspended solids. The trend analysis by principal component analysis (PCA) during 2 years revealed the significant variations in water quality in the study area. Spatial water qualities were discriminated into 3 clusters by PCA; station cluster in the surface water 1, 2~11, and 12~16, the bottom water 1, 2~7, and 8~16. Annual bimonthly water qualities were clearly discriminated into 3 clusters by PCA. But tend of cluster in the surface and bottom water was difference, period most of the research was low in nutrient. Ecology-based water quality criteria was a good level of grade II. Bimonthly results are shown as III grade(normal) at June and August, II grade(good) at October and December and I grade for February and April. Water quality was showed by the input of fresh water same as those of Kyoungin coastal area, Asan coastal area, Gunsan coastal and Mokpo coastal area in the Cheonsu.

Preventive effects of Saponariae Vaccariae Semen and Melandryi Firmi Herba on hyperlipidemia and liver damage induced by alcohol (왕부류행(王不留行)과 경엽여루채(硬葉女婁菜)가 알콜 투여로 유발된 흰쥐의 고지혈증과 간 손상의 예방에 미치는 영향)

  • Choi, Jae-Young;Seo, Bu-Il;Oh, Dal-Seok;Park, Ji-Ha;Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.27 no.1
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    • pp.27-34
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    • 2012
  • Objectives : This study was performed to compare the preventive effect of water extracts from Saponariae Vaccariae Semen(SVS) and Melandryi Firmi Herba(MFH) on hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, I fed rat on 25% alcohol for 55 days. And each extract was administrated for the same period. I measured the serum component in rat's blood, body weight and weight of liver. Results : At first, I observed effects of SVS and MFH on hyperlipidemia induced by alcohol. SVS and MFH group didn't show the significant decrease of total cholesterol in comparison with those of the control group. SVS and MFH group showed the significant increase of HDL-cholesterol in comparison with those of the control group. SVS group showed the significant decrease of triglyceride in comparison with those of the control group, but MFH group didn't show the significant decrease of triglyceride in comparison with those of the control group. SVS group showed the significant increase of body weight in comparison with those of the control group at 4weeks and 8weeks. But, MFH group didn't show the significant changes of body weight in comparison with those of the control group at 4weeks and 8weeks. By the way, SVS group showed the significant decrease of triglyceride in comparison with those of MFH group. SVS group showed the significant increase of body weight in comparison with those of MFH group at 8weeks. At second, I observed effects of SVS and MFH on liver damage induced by alcohol. SVS and MFH group showed the significant decrease of AST(aspartate aminotransferase), ALT(alanine aminotransferase), ALP(alkaline phosphatase) and LDH(lactate dehydrogenase) in comparison with those of the control group. SVS group showed the significant increase of liver weight in comparison with those of the control group, but MFH group didn't show the significant increase of liver weight in comparison with those of the control group. By the way, SVS group showed the significant increase of liver weight in comparison with those of MFH group. Conclusions : Reviewing these experimental results, it suggests that water extracts from SVS and MFH have pharmaceutical preventive efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate the pharmaceutical efficacy of these in depth.

Application of Dielectric Sensor for Soil Moisture Measurement (토양 수분 측정을 위한 유전율식 쎈서 연구)

  • Oh, Yong-Taeg;Oh, Dong-Shig;Song, Kwan-Cheol;Shin, Jae-Sung;Im, Jung-Nam
    • Korean Journal of Soil Science and Fertilizer
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    • v.31 no.2
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    • pp.85-94
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    • 1998
  • Due to relatively high permittivity of water in soils, we placed the soil condenser into soils to measure the soil moisture content. The soil condenser was made with two insulated iron sticks. The capacitance of the soil condenser was determined by the pulse period from RC type oscillation circuit and the highest voltage output accepting 10MHz pulse. After zero point adjustment, the measured relative capacitance percentage (RCS) to the standard condenser obtained by the oscillation circuit almost linearly correlated with the end depth of the sensor submerged in water. The RC type oscillation was disturbed by many sensor installed in a close distance in one place, presumably resulting in that the sensor sticks played as a interfering antennas generating or accepting electron waves from them. The temperature dependance of the output from the sensors could be corrected through experimentally determined revision function. Although lineal correlation was found between soil moisture and RCS, users should derive their own correlation function for every sensor to measure soil moisture, because the outputs were influenced by the installation depth and layout in the soil. The voltage type sensor responded inversely with soil moisture content and so was not suitable to the accurate measurement of soil moisture, but allows high economic benefit in various application such as simplified measurement of soil moisture and irrigation line control because of its low component count. The voltage type moisture sensor could be reinforced by relay controlling circuit to open and to close the solenoid valves respectively at optimal limits of the least and the most soil moisture according to user's adjustment.

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Psychometric Properties of the Persian Version of Satisfaction with Care EORTC-in-patsat32 Questionnaire among Iranian Cancer Patients

  • Pishkuhi, Mahin Ahmadi;Salmaniyan, Soraya;Nedjat, Saharnaz;Zendedel, Kazem;Lari, Mohsen Asadi
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10121-10128
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    • 2015
  • Background: Cancers impose an increasing burden on health of the populations and individuals, but little is known about cancer patient satisfaction with care. The aim of this study was to assess the psychometric properties of the Persian version of European Organisation for Research and Treatment of Cancer (EORTC) In-Patsat32, as a recently developed questionnaire to assess cancer patient satisfaction with care and information provided during hospital admission. Materials and Methods: Complying with EORTC protocols, the Persian version of Inpatsat32 was translated and piloted in a small group of patients, then applied to 380 cancer patients admitted to different oncology wards in Tehran. Validity (convergent, discriminant, and divergent) and reliability of the tool was assessed through using multitrait analysis, factor analysis, intraclass correlations, Chronbach's alpha and test-retest (on a sample of 70 patients). Results: Good acceptance and high sensitivity of the questionnaire with low floor and ceiling effects were recognized, indicating power of the instrument to detect differences between groups with heterogeneous levels of satisfaction. Multitrait scaling analyses supported the convergent validity of the majority of scales (correlation coefficient >0.4) and favorable discriminant validity (item own scale correlation >0.8). There was no correlation between In-patsat32 scales and the EORTC-C30, which measures different concepts, confirming divergent validity of the tool. Internal consistency for all domains was high (${\alpha}$ >0.70) except for the hospital access score and the test-retest reliability was excellent (r=0.86-0.96). There was a weak responsiveness to change except for nurses technical skills. Principle component analysis confirmed five domains with much improved internal consistency (${\alpha}$ >0.9). Conclusions: The Persian version of the EORTC-in-patsat32 module is a reliable and valid instrument to measure cancer patient satisfaction with care received during their hospitalization period and can be utilized in clinical cancer research.

Study on the Thermal Buffer Mass and Phase Change Material for Thermal Control of the Periodically Working Satellite Component (주기적으로 작동하는 위성부품 열제어용 열적완충질량과 이를 대체할 상변화물질을 이용한 열제어부품의 비교연구)

  • Kim, Taig Young;Seo, Jung Gi;Hyun, Bum-Seok;Cheon, Hyeong Yul;Lee, Jang-Joon
    • Journal of the Korean Society for Aeronautical & Space Sciences
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    • v.42 no.12
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    • pp.1013-1019
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    • 2014
  • Solid-liquid Phase Change Material(PCM) as a thermal control hardware for the electro-optical payload of low earth orbit satellite is numerically studied which can be substituted with Thermal Buffer Mass(TBM). The electro-optical module in LEO satellite is periodically work and high heat is dissipated during the imaging period, however, the design temperature range is very tight and sensitive. In order to handle this problem TBM is added and as a result the time constant of the module temperature increases. TBM is made of Al6010 and its mass directly affects the system design. To save the mass PCM is suggested in this study. The latent heat of melting or solidification is very high and small amount of PCM can play a role instead of TBM. The result shows that only 12% of TBM mass is enough to control the module temperature using PCM.

Studies on Analysis of Joseon Lacquer Layer (조선시대 칠도막 분석연구)

  • Choi, Seok-Chan;Kim, Sun-Duk;Yi, Yong-Hee;Ko, Soo-Rin;Ham, Seung-Wook
    • Journal of Conservation Science
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    • v.27 no.4
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    • pp.371-380
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    • 2011
  • For studying of the characteristics and structures of material in lacquer layer in Joseon Dynasty, 6 types and 7 pieces of sample were observed with the optical microscope and the polarizing microscope. For analyzing, SEM-EDS and FT-IR were used and TOF-SIMS was also used on trial. The former is directly varnished on the iron layer so the sample includes more iron component than the others. In the results of the trial analyzing in TOF-SIMS, it is possible to verify the minerals on the foundation layer with the infinitesimalsample. The analysis results of lacquer layer with FT-IR are compared with previous studies and all the samples have the spectrum of the lacquer. Through the result of the Joseon lacquer layer, there are not many samples, however, when it compared with unified Silla, the period of the Three States, and the previous era, the lacquer layers are simpler than the relics from previous era. It looks to have the relation with the simplification of manufacturing method because of expanding of the using of lacquer wares.

Analysis of Sports Medical Care Utilization during the 24th Seoul Olympic Games (서울올림픽대회 기간중 스포츠의료 이용에 관한 분석)

  • Yu, Seung-Hum;Sohn, Myong-Sei;Lee, Young-Doo;Park, Eun-Cheol;Kim, Chun-Bae
    • Journal of Preventive Medicine and Public Health
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    • v.22 no.1 s.25
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    • pp.136-145
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    • 1989
  • This study made a descriptive analysis of the cumulative amount and rate of sports medical care utilization during the 24th Seoul Olympic Games by the participating athletes, officials, etc. The sports medical care utilization was a component of the total medical care use and was basically caused by the prevention and treatment of sports injuries. The analytic data were derived from the Olympic Health Management Information System(OHMIS) of the SLOOC and the Korea Athlete Trainer Association(KATA). These were analyzed according to the quantity of physician visits and the utilization rate, which was the amount of utilization divided by the total number of participating persons. The results were as follows: Firstly, the sports medical care utilization by the persons participating in the Seoul Olympics amounted to 17.9% of the total medical care utilization. The venue medical services utilization accounted for 54.7% of the total physician visits, which was larger than the village medical center's utilization. The number of physician visits per hundred persons during the 2 week period in the venue clinic was 3.03 and that of the village medical center was 2.51, therefore, the total was 5.54. Secondly, athletes accounted for 82.3% and officials 12.2% in the sports medical care utilization by participants. These results were because athletes, who were directly related to the games, called extremely often on the physicians. The utilization rate of sports medical care by athletes was 34.29. Thirdly, the sports medical demand according to type of therapy could be ranked from high to low in the following order: sports massage, thermal therapy, and electrical stimulation treatment, etc. The department of physical therapy in the village medical center was used a great deal. Fourthly, the trend of daily sports medical care utilization by the athletes showed a bell shape centering around the opening day of the Seoul Olympic Games. The utilization rate of athletes was 2.3; however, that of officials was 0.6. Lastly, the sports medical demand was calculated according to the continents, and Central America, Africa and Middle-East Asia proved to have a higher rate of sports medical care utilization than the more powerful and industrialized continent or regions.

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