• Korean Journal of Ichthyology
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• v.23 no.1
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• pp.37-45
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• 2011

Seasonal variation in species composition and abundance of fish larvae assemblages in the south-western Jinhae Bay were investigated monthly in 2009. During the study period, 49 larvae species belonging to 24 families were collected. The dominant species were Clupea pallasii, Hexagrammos otakii, Konosirus punctatus, Engraulis japonicus, Parablennius yatabei, and Omobranchus elegansei. These six species accounted for 92.7% of the total number of individuals collected. The number of species, number of individuals, and species diversity indices fluctuated with the seasons. The peak number of species and individuals occurred in July and January, respectively. Principal component analysis(PCA) and correlation analysis showed that variation in monthly water temperature could act as an indicator of seasonal variation in community structure and abundance of the dominant species; in particular, those of C. pallasii, H. otakii, E. japonicus and P. yatabei corresponded with the water temperature.

• Journal of Oriental Neuropsychiatry
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• v.21 no.2
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• pp.45-60
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• 2010

Objectives : The aim of this study was to investigate the correlation between the effectiveness of Brief Qigong-based Stress Reduction Program(BQSRP) and personality. Methods : Twenty nine women and nine men from the community with symptoms of distress(mean age 39.4 years, SD=11.4) were randomized into a group receiving a 4-week intervention of BQSRP(n=19) or a waiting-list control group. All subjects completed the temperament and character inventory (TCI) before the intervention. Before and after the intervention period, questionnaires were completed on perceived stress scale(PSS), anxiety, and quality of life. Results : 1. Those who have higher temperament of harm avoidance or lower character of self-directedness showed higher PSS, Hwa-Byung character, Hwa-Byung symptom, STAI and lower WHOQOL-BREF scores. 2. In the BQSRP training group, a correlation analysis demonstrated an association between higher temperament of harm avoidance and greater improvement of perceived stress and an association between lower character of self-directedness and greater improvement of perceived stress. 3. Those who have high Hwa-Byung symptom scores prefer the breathing meditation and there were no differences in effects of BQSRP group by the preference Brief Qigong-based Meditation(BQM) component. Conclusions : These results suggest that a BQSRP training may be effective for those with higher harm avoidance trait and low self-directedness.

• Korean Journal of Clinical Pharmacy
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• v.24 no.3
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• pp.193-198
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• 2014

Objective: This study was conducted to compare the adherence, clinical and economical utility of fixed-dose combination tablets of sitagliptin/metformin with concomitant administration of sitagliptin and metformin in patients with type 2 diabetes mellitus. Methods: Adherence was measured as the medication possession ratio (MPR) of ${\geq}80%$, and MPR was calculated as the number of total prescription days divided by the total treatment period. Hemoglobin $A_{1C}$ ($HbA_{1c}$) differences between baseline and predetermined periods were analyzed. Proportions of patients who achieved $HbA_{1c}$ less than 6.5% for three or more consecutive times were compared. To evaluate cost-effectiveness, prices of sitagliptin, metformin and sitagliptin/metformin tablets were investigated. Results: More than 90% of patients showed adherence in both groups (92.0% in fixed-dose combination group vs 95.9% in concomitant administration group), and there was no statistically significant difference (P = 0.113). Proportion of patients with HbA1c less than 6.5% for three or more consecutive times tended to be somewhat higher in fixed dose combination group than in concomitant administration group without a statistically significant difference (32.6% vs. 28.0%, P = 0.344). Total price of metformin and sitagliptin was cheaper up to 222 KRW in the case of fixed-dose combination tablets compared to the case of concomitant administration. Conclusion: The sitagliptin/metformin fixed-dose combination tablet had a similar patient adherence and was not significantly different in efficacy to the concomitant administration of each component. In terms of drug prices, fixed-dose combination tablets were cheaper than concomitant administration of each tablet.

• IMMUNE NETWORK
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• v.6 no.3
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• pp.117-122
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• 2006

Background: Caveolin, a family of integral membrane proteins are a principal component of caveolae membranes. In this study, we investigated the effect of p38 kinase on differentiation and on inflammatory responses in sodium nitroprusside (SNP)-treated chondrocytes. Methods: Rabbit articular chondrocytes were prepared from cartilage slices of 2-week-old New Zealand white rabbits by enzymatic digestion. SNP was used as a nitric oxide (NO) donor. In this experiments measuring SNP dose response, primary chondrocytes were treated with various concentrations of SNP for 24h. The time course of the SNP response was determined by incubating cells with 1mM SNP for the indicated time period $(0{\sim}24h)$. The cyclooxygenase-2 (COX-2) and type II collagen expression levels were determined by immunoblot analysis, and prostaglandin $E_2\;(PGE_2)$ assay was used to measure the COX-2 activity. The tyrosine phosphorylation of caveolin-1 was determined by immunoblot analysis and immunostaining. Results: SNP treatment stimulated tyrosine phosphorylation of caveolin-1 and activation of p38 kinase. SNP additionally caused dedifferentiation and inflammatory response. We showed previously that SNP treatment stimulated activation of p38 kinase and ERK-1/-2. Inhibition of p38 kinase with SB203580 reduced caveolin-1 tyrosine phosphorylation and COX-2 expression but enhanced dedifferentiation, whereas inhibition of ERK with PD98059 did not affect caveolin-1 tyrosine phosphorylation levels, suggesting that ERK at least is not related to dedifferentiation and COX-2 expression through caveolin-1 tyrosine phosphorylation. Conclusion: Our results indicate that SNP in articular chondrocytes stimulates dedifferentiation and inflammatory response via p38 kinase signaling in association with caveolin-1 phosphorylation.

• Proceedings of the Korean Institute of Navigation and Port Research Conference
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• 2002.11a
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• pp.155-159
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• 2002

Wire ropes are used in a myriad of various industrial applications such as elevator, mine hoist, construction machinery, lift, and suspension bridge. Especially, wire rope of crane is important component to container transfer. If it happens wire rope failures in operating, it may lead to safety accident, economic power loss by productivity decline, competitive power decline of container terminal and so on. To solve this problem, we developed wire rope fault detecting system as a portable instrument, and this system is consisted of 3 parts that fault detecting part using hall sensor, permanent magnets and analog unit, and digital signal processing part using data acquisition card, monitoring part using wavelet transform, denoising method. In this paper, a wire rope is scanned by this system after makes several broken parts on the surface of wire rope artificially. All detected signal has external noise or disturbance according to circumstances. So, we applied to discrete wavelet transform to extract a signal from noisy data that was used filter. In practical applications of denoising, it is shown that wavelet pursue it with little information loss and smooth signal display. It is verified that the detecting system by denoising has good efficiency for inspecting faults of wire ropes in service. As a result, by developing this system, container terminal could reduce expense because of extension of wire ropes exchange period and could competitive power. Also, this system is possible to apply in several fields like that elevator, lift and so on.

• The Korean Journal of Pesticide Science
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• v.11 no.1
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• pp.46-51
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• 2007

In this study, two commercial mating disruptors were compared in terms of disruption of Oriental fruit moth, Grapholita molesta, male orientation, in which a new dispenser type, $SPLAT^{(R)}$, was compared with a current dispenser type, $Isomate^{(R)}$-M ROSSO. For this assessment, the last three year field monitoring data were analyzed for the efficacy of Isomate type dispenser. Then two commercial dispensers were compared in different localities with sub-locality replications during identical monitoring period from mid February to late August. There appeared to be four adult population peaks, in which the overwintering population size was positively correlated with the following reproductive population sizes. Isomate type dispenser effectively suppressed G. molesta populations during all growing seasons with some annual variation in its efficacy. Between two dispensers, SPLAT type was much effective. The difference in their efficacy may be caused by the difference in composition of major pheromone component.

• Korean Journal of Pharmacognosy
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• v.31 no.3
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• pp.310-319
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• 2000

WooHwangChungSimWon is a traditional prescription formula for treating with hypertension, arteriosclerosis, coma, and stroke in China, Korea, and Japan. In the new prescription of WooHwangChungSimWon, the civet is substituted for the musk, the major component of WooHwangChungSimwon, because of the prohibition law (CITES) on the commercial use of musk. We have made a comparative study of the effects on the hypertension and contractile force of heart between the musk-containing and civet-containing WooHwangChungSimWon. The SHR rats were used for investigating the effects on the hypertension and the rabbits were used for investigating effects on the contractile force of isolated heart. The blood pressure which was recorded during the adminstration period showed that all the samples except the low dose of musk-containing WooHwangChungSimWon decreased the blood pressure, and the effects on the heart works of all the samples were higher than control group, which resulted from the examination of isolated heart. These results suggest that all the musk-containing and civet-containing WooHwangChungSimWon formula have similar protective effects on hypertension and palpitation.

• The Korea Journal of Herbology
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• v.26 no.3
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• pp.31-36
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• 2011

Objectives : This study was performed to investigate the effect of water extracts from Phyllostachys Folium(PF) on hyperlipiderma and liver damage induced by alcohol. Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And extract was administrated for the same period. We measured the serum component in rat's blood, body weight and weight of liver. Results : At first, we observed effects of PF on hyperlipidemia induced by alcohol. PF group didn't show significant change of total cholesterol in comparison with those of the control group. PF group showed significant increase of HDL(High-Density lipoprotein) cholesterol in comparison with those of the control group. PF group showed significant decrease of triglyceride in comparison with those of the control group. PF group showed significant increase of body weight in comparison with those of the control group at 4weeks and 8weeks. At second, I observed effects of PF group on liver damage induced by alcohol. PF group showed significant decrease of GOT, GPT, ALP and LDH in comparison with those of the control group. PF group showed significant increase of liver weight in comparison with those of the control group. Conclusions : Reviewing these experimental results, it appears that water extracts from Phyllostachys Folium(PF) have pharmaceutical efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

• Animal cells and systems
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• v.16 no.2
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• pp.162-171
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• 2012

We investigated food webs of a $Salix$ $subfragilis$-dominated wetland in the Janghang wetland in the Hangang estuary, which is very close to the Demilitarized Zone, along the west coast of Korea. Our study focused on understanding sesarmine crab ($Sesarma$ $dehaani$)-related food webs in a $S.$ $subfragilis$ forest. For our study, we used carbon and nitrogen stable isotopes and fatty acid biomarkers. We collected samples of plants, animals, and detrital sediment from four quadrats ($5{\times}5m^2$) set in the $S.$ $subfragilis$ community. Samples were collected from September 2006 to June 2009, except during the winter hibernation period of $S.$ $dehaani$. In the wet season, the sediment showed relatively high ${\delta}^{13}C$ and low ${\delta}^{15}N$ signatures compared with relatively low ${\delta}13C$ and high ${\delta}15N$ signatures in the dry season. Mature $S.$ $dehaani$ appeared to feed on fresh leaves and other carbon sources, such as immature individuals or fish, in addition to detrital sediment, which appeared to be the main carbon source for immature crabs. Principal component analysis of fatty acid biomarkers of $S.$ $dehaani$ showed a clear difference between immature individuals (10-30 mm) and mature ones (larger than 30 mm), indicating that the main food source for immature crabs was detrital sediment, whereas mature crabs foraged plants in addition to consuming detrital sediment. On the basis of our results from stable isotope and fatty acid analyses, mature $S.$ $dehaani$ appeared to feed on detrital sediment and fresh leaves of $S.$ $subfragilis$ in summer in addition to engaging in cannibalism of immature individuals.

• Atmosphere
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• v.24 no.2
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• pp.131-140
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• 2014

The "Barents Oscillation (BO)", first designated by Paul Skeie (2000), is an anomalous recurring atmospheric circulation pattern of high relevance for the climate of the Nordic Seas and Siberia, which is defined as the second Emperical Orthogonal Function (EOF) of monthly winter sea level pressure (SLP) anomalies, where the leading EOF is the Arctic Oscillation (AO). BO, however, did not attracted much interest. In recent two decades, variability of BO tends to increase. In this study, we analyzed the spatio-temporal structures of Atmospheric internal modes such as Arctic Oscillation (AO) and Barents Oscillation (BO) and examined how these are related with Arctic warming in recent decade. We identified various aspects of BO, not dealt in Skeie (2000), such as upper-level circulation and surface characteristics for extended period including recent decade and examined link with other surface variables such as sea-ice and sea surface temperature. From the results, it was shown that the BO showed more regionally confined spatial pattern compared to AO and has intensified during recent decade. The regional dipolelar structure centered at Barents sea and Siberia was revealed in both sea-level pressure and 500 hPa geopotential height. Also, BO showed a stronger link (correlation) with sea-ice and sea surface temperature especially over Barents-Kara seas suggesting it is playing an important role for recent Arctic amplification. BO also showed high correlation with Ural Blocking Index (UBI), which measures seasonal activity of Ural blocking. Since Ural blocking is known as a major component of Eurasian winter monsoon and can be linked to extreme weathers, we suggest deeper understanding of BO can provide a missing link between recent Arctic amplification and increase in extreme weathers in midlatitude in recent decades.