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Preventive effects of Injinho-tang and Haninjinho-tang on hyperlipidemia and liver damage induced by alcohol (인진호탕(茵蔯蒿湯)과 한인진호탕(韓茵蔯蒿湯)이 알코올 투여(投與)로 유발(誘發)된 흰쥐의 고지혈증(高脂血症)과 간(肝) 손상(損傷)의 예방(豫防)에 미치는 영향(影響))

  • Kim, You-Chang;Kim, Seong-Mo;Park, Ji-Ha;Seo, Bu-Il;Choi, Hong-Sik
    • The Korea Journal of Herbology
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    • v.21 no.3
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    • pp.47-54
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    • 2006
  • Objectives : This study was performed to compare the preventive effect of water extracts from Injinho-tang and Haninjinho-tang on hyperlipidemia and liver damage induced by alcohol. Methods : Except for the normal group, we fed rat on 25% alcohol for 55 days. And each extract was administrated for the same period. We measured the serum component in rat's blood, body weight and weight of liver. Results : 1. At first, we observed effects of Injinho-tang and Haninjinho-tang on hyperlipidemia induced by alcohol. Injinho-tang group showed significant decrease of triglyceride, body weight in comparison with those of the control group. Haninjinho-tang group showed significant decrease of total cholesterol, triglyceride in comparison with those of the control group. I 2. At second, we observed effects of Injinho-tang and Haninjinho-tang on liver damage induced by alcohol. lnjinho-tang group showed significant decrease of AST (aspartate aminotransferase), ALT (alanine aminotransferase), ALP (alkaline phosphatase), liver weight in comparison with those of the control group. Haninjinho-tang group showed significant decrease of AST (aspartate aminotransferase), ALT (alanine aminotransferase) in comparison with those of the control group. Conclusion : Reviewing these experimental results, it appears that water extracts from Injinho-tang and Haninjinho-tang have pharmaceutical preventive efficacy on hyperlipidemia and liver damage induced by alcohol. Therefore further additional study should be conducted to elucidate in depth the pharmaceutical efficacy of these.

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Effect of the characteristics of buoy on the holding power of trapnet (부이의 특성이 통발어구의 고정력에 미치는 영향)

  • LEE, Gun-Ho;CHO, Sam-Kwang;KIM, In-Ok;CHA, Bong-Jin;JUNG, Seong-Jae
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.53 no.4
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    • pp.309-316
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    • 2017
  • In this paper, numerical modeling is conducted to analyze the tension of an anchor line by varying the size and drag coefficient of a buoy when the trapnet is influenced by the wave and the current simultaneously. A mass-spring model was used to analyze the behavior of trapnet underwater under the influence of waves and current. In the simulation of numerical model, wave height of 3, 4, 5 and 6 m, a period of 4.4 s, and the flow speed of 0.7 m/s were used for the wave and current condition. The drag coefficients of buoy were 0.8, 0.4 and 0.2, respectively. The size of buoy was 100, 50 and 25% based on the cylindrical buoy ($0.0311m^3$) used for swimming crab trap. The drag coefficient of the trapnet, the main model for numerical analysis, was obtained by a circular water channel experiment using a 6-component load cell. As a result of the simulation, the tension of the anchor line decreased proportional to buoy's drag coefficient and size; the higher the wave height, the greater the decrease rate of the tension. When the buoy drag coefficient and size decreased to one fourth, the tension of the anchor line decreased to a half and the tension of the anchor line was lower than the holding power of the anchor even at 6 m of wave height. Therefore, reducing the buoy drag coefficient and size appropriately reduces the trapnet load from the wave, which also reduces the possibility of trapnet loss.

Spatial Characterization of Water Pollution in the Urban Stream Watershed (Gap Stream), Korea (도시하천(갑천) 유역에서 수질오염의 공간적 특성)

  • Lee, Heung-Soo;Hur, Jin;Jeong, Seon-A;Hwang, Soon-Jin;Shin, Jae-Ki
    • Journal of Korean Society on Water Environment
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    • v.22 no.5
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    • pp.943-951
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    • 2006
  • Spatial distribution of water pollution in the Gap Stream was investigated from October to November, 2005. Sampling was conducted three times including effluents discharged from a wastewater treatment plant (WWTP) and a dam reservoir during the low-flow period. As a typical urban stream, total nitrogen and inorganic nitrogen concentrations increased toward downstream. Ammonia concentration was the highest in the treated water of the wastewater treatment plant and the lowest nitrate concentration was found in the effluent of the dam reservoir. A part of soluble reactive phosphorous (SRP) in total phosphorous was 22~54% in the upstream reach of WWTP in the Gap Stream whereas 68~73% in the downstream reach. Mean chlorophyll-a concentration ranged from 1.6 to $11.0{\mu}g/L$ and it tends to increase toward downstream except for WWTP effluent. As expected, untreated wastewater and WWTP effluent were suggested as the major sources of water pollution in the Gap Stream. In this study, the water pollution of the Gap Stream is a significant undergoing typical eutrophication, caused by excessive phosphorus and nitrogen nutrients from WWTP located in the watershed. As a result, the critical factor for the water pollution was evaluated to dissolved inorganic nitrogen and phosphorus nutrients. Particularly, SRP is a most important for the eutrophication. It suggest that may occur in the most urban streams of Korean peninsula. Therefore, because the necessity of water pollution management in the urban stream, inorganic N and P nutrients should be included as an essential component of water quality criteria in the advanced water quality project of Korean Government by enforcing of water quality assessment and total maximum daily loads (TMDLs).

Taste Components of Traditional Kochujang Prepared with Various Raw Materials (담금원료에 따른 전통식 고추장의 숙성 중 맛성분의 변화)

  • Shin, Dong-Hwa;Kim, Dong-Han;Choi, Ung;Lim, Mi-Sun;An, Eun-Young
    • Korean Journal of Food Science and Technology
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    • v.29 no.5
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    • pp.913-918
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    • 1997
  • Taste components of traditional kochujang prepared with various raw materials, were investigated during 90 days of fermentation. The major free sugars, maltose and glucose, were higher in malt added kochujang than others. The major organic acids of kochujang were succinic and citric acids, followed by formic acid. The contents of succinic acid in the kochujang decreased during fermentation, whereas that of citric acid increased. Purple sweet potato kochujang was highest in total free amino acids. The major free amino acids were glutamic acid, serine and aspartic acid. They remarkably increased during fermentation. Among the nucleotides and their related components in kochujang, cytidine-5-monophosphate was the most abundant component at the beginning of aging period, while hypoxanthine increased remarkably during fermentation. Kochujang prepared with purple sweet potato Chinese matrimony vine contained higher amounts of organic acids and nucleotides than the others.

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Effects of Planting Density and Cutting Height on Production of Leaves for Processing Raw Materials in Goji Berry (구기자나무의 재식밀도 및 예취높이가 가공용 잎 생산에 미치는 영향)

  • Paik, Seung Woo;Lee, Jeong;Yun, Tug Sang;Park, Young Chun;Lee, Bo Hee;Son, Seung Wan;Ju, Jung Il
    • Korean Journal of Medicinal Crop Science
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    • v.28 no.2
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    • pp.136-141
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    • 2020
  • Background: The leaves of the goji berry (Lycium chinense Mill.) are used as raw materials in processing and by replace fruits to some extent. The reason is that the leaves are cheaper, however, betaine content is higher than in the fruits. These experiments were conducted to determine the planting density and cutting height for producing a large number of leaves. Methods and Results: The cultivar 'Myeongan' with many branches was used. When the shoot height reached 50 cm - 70 cm, harvesting was possible four times a year. The time to next harvest was approximately 38 days after regeneration of new shoots. Leaf quantity was in the order of 1st > 2nd > 4th > 3rd harvest. Insect damage occurred during the third harvest in late July and early August, therefore, eco-friendly control was necessary. The total yield was higher at the planting density 60 cm × 30 cm than that of 60 cm × 20 cm or 60 cm × 40 cm. The yield at cutting for shoot height of 60 cm was increased by 6.3 percent compared to that of 50 cm, At the cutting height of 70 cm, harvest was difficult owing to hardening of stems and thorns. Betaine content, an indicator component of goji berry, was not significantly different according to planting densities and cutting height. Conclusions: The ideal cutting period to produce leaves of goji berry for processing is when the shoots grow to approximately 60 cm, and the leaves can be harvested 4 times a year. The dried-leaf yield was highest at the planting density of 60 cm × 30 cm.

A Study on the Korean Interest Rate Spread Prediction Model Using the US Interest Rate Spread : SVR-Ensemble (RNN, LSTM, GRU) Model based (미국 금리 스프레드를 이용한 한국 금리 스프레드 예측 모델에 관한 연구 : SVR-앙상블(RNN, LSTM, GRU) 모델 기반)

  • Jeong, Sun-Ho;Kim, Young-Hoo;Song, Myung-Jin;Chung, Yun-Jae;Ko, Sung-Seok
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.43 no.3
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    • pp.1-9
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    • 2020
  • Interest rate spreads indicate the conditions of the economy and serve as an indicator of the recession. The purpose of this study is to predict Korea's interest rate spreads using US data with long-term continuity. To this end, 27 US economic data were used, and the entire data was reduced to 5 dimensions through principal component analysis to build a dataset necessary for prediction. In the prediction model of this study, three RNN models (BasicRNN, LSTM, and GRU) predict the US interest rate spread and use the predicted results in the SVR ensemble model to predict the Korean interest rate spread. The SVR ensemble model predicted Korea's interest rate spread as RMSE 0.0658, which showed more accurate predictive power than the general ensemble model predicted as RMSE 0.0905, and showed excellent performance in terms of tendency to respond to fluctuations. In addition, improved prediction performance was confirmed through period division according to policy changes. This study presented a new way to predict interest rates and yielded better results. We predict that if you use refined data that represents the global economic situation through follow-up studies, you will be able to show higher interest rate predictions and predict economic conditions in Korea as well as other countries.

An Analysis of the Spatial Distribution of Multipath Fading using Miniaturized Experimental Setup (축소 실험 모형을 이용한 다중경로 페이딩의 공간분포 특성 분석)

  • Hur, Jung;Shin, Seong-Hyeon;Han, Myoung-Woo;Lee, Chang-Eun;Choi, Hong-Ju
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.9 no.4
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    • pp.450-461
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    • 1998
  • The spatial distribution of multipath fading using miniaturized experimental setup was analyzed. The spatial Fourier transform was carried out for the analysis of the period of fading and we could find out spatial frequency component of fading. Thus the analysis using this method shows the validity of miniaturized experimental setup. The miniaturized experimental setup was made by 5 times reducing of the real size. The simulation was performed at 2 GHz and the measurement was carried out at 10 GHz. Automatic antenna moving system was made for exact measurement of the multipath fading. Both simulated and measured results in miniaturized experimental setup were shown by electric field distribution and spatial frequency density distribution curves.

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The Effect of Tailored Health Care Program Based on Sasang Constitution for Vietnamese (사상체질에 기반한 베트남 맞춤형 건강관리 프로그램 효과)

  • Kwon, Ji-Hye;Kim, Yun-Young;Park, Ki-Hyun;Lee, Si-Woo;Yoo, Jong-Hyang
    • Journal of Sasang Constitutional Medicine
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    • v.25 no.2
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    • pp.98-107
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    • 2013
  • Objectives This study aimed to develop the tailored health care program based on Sasang constitution for Vietnamese and evaluate the effect of them. Methods This research was executed from Sep. $1^{st}$ 2012 to Nov. $30^{th}$ 2012 in Vietnam Hanoi National Hospital of Traditional Medicine. All of 50 vietnamese subjects participated in the tailored health care program for 8 weeks after constitutional diagnosis. During the applicable period of the 8 weeks program, follow-up visits was conducted after 1 week, 4 week, and 8 week from the first visit, and Quality of life, Anxiety, Fatigue and Sleep Quality were measured. Results The tailored Health Care Program was applied to the subjects for eight weeks. The quality of life scores of Physical Functioning (p=0.006), Pain (p=0.003) and Physical Component Score (p=0.009) were significantly increased, and the sleep quality of subjects was improved after the tailored health care program is applied. Conclusions The tailored health care program based on Sasang constitution affected to some items about the quality of life and sleep quality of the subjects. however, this result can not be generalized to all Vietnamese, and various follow-up studies are needed.

Association of dietary patterns with overweight risk and all-cause mortality in children with cancer

  • So, Eunjin;Kim, Jeeyeon;Joo, Sehwa;Lee, Jisun;Joung, Hyojee
    • Nutrition Research and Practice
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    • v.11 no.6
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    • pp.492-499
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    • 2017
  • BACKGROUND/OBJECTIVES: This study aimed to investigate the association of dietary patterns with overweight risk and all-cause mortality in pediatric cancer patients. SUBJECTS/METHODS: Prospective cohort study was undertaken; 83 cancer patients admitted to the pediatric cancer ward at a university hospital in Seoul were included and followed for obesity and death over 24 months. Food consumption data were collected from patients using validated meal order sheets for breakfast, lunch, and dinner at the pediatric cancer ward over 3 days. Using principal component analysis, three dietary patterns were derived from 29 food groups. RESULTS: Eighteen deaths occurred among the patient cohort during the follow-up period. The "spicy & fried meat and fish" dietary pattern was positively associated with overweight risk at both baseline [odds ratio (OR) = 4.396, 95% confidence interval (CI) = 1.111-17.385, P for trend = 0.023] and after 6 months (OR = 4.088, 95% CI = 1.122-14.896, P for trend = 0.025) as well as all-cause mortality (hazard ratios = 5.124, 95% CI = 1.080-24.320, P for trend = 0.042), when comparing the highest and lowest tertiles after adjusting for covariates. The "fish, egg, meat, and fruits & vegetables" dietary pattern was associated with lower overweight risk after 24 months (OR = 0.157, 95% CI = 0.046-0.982, P for trend = 0.084). CONCLUSION: The results imply that dietary patterns might be associated with weight gain and premature death among pediatric cancer patients.

Mineral Leaching from Air-Dried Forages (마른 목초(牧草) 잎으로 부터의 무기물(無機物) 용출(溶出))

  • Kim, S.D.;YOSHIDA, Shigekata
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.19 no.3
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    • pp.265-272
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    • 1999
  • In this study in order to know the behavior of mineral nutrients from forage plant to soil in a grassland ecosystem, the leaching of minerals (K, Mg, Ca, N and P) from air-dried (dead) plant body was investigated by putting orchardgrass (Dactylis glomerata L.) hay on meadow during a month with seasonal changes. The results obtained were as follows; 1) The K content of the forage, not stable during the experimental seasons, tended to decrease in the summer of 1986, while the Mg and Ca contents increased in the summer. The reason might be a different response (solubility or leaching liability) of the monovalent mineral (K) and divalent ones (Mg and Ca) in the forage to rainfall. 2) The percentage of P to the initial amount in the forage showed larger decrease in a rainy period (Feb.~Mar., 1986) and during the rainy summer (May to July). The P component of the forage might be easily leached with water. 3) The percentage of the four minerals (Ca, N, Mg, K) remained the least in the period of (Jun.~Jul., 1986), 4) Though the percentage of remained Mg and N of the forage varied very similarly, the percentage of remained N was higher than that of Mg during periods before summer (January to May), while after the period the ratio of the Mg seemed to be higher than that of the N (June to December), 5) During the periods until (May~Jun., 1986) the percentage of remained K and P of the forage varied in very similar pattern, and the order of remained mineral was as follows; $Ca>N{\geq}Mg>P=K$. But from the period of (Jun-Jul) the ratio of P remained in the forage increased nearly up to the ratio of N, and the order was as follows; $Ca>Mg{\geq}N{\geq}P>K$.

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