• Maxillofacial Plastic and Reconstructive Surgery
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• v.41
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• pp.23.1-23.10
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• 2019

The choice of surgical technique in orthognathic surgery is based primarily on the surgical treatment objectives (STO), which is a fundamental component of the orthognathic treatment process. In the conventional orthodontics-first approach, presurgical planning can be performed twice, during the preorthodontic (initial STO) and presurgical phases (final STO). Recently, a surgery-first orthognathic approach (SFA) without presurgical orthodontic treatment has been introduced and combined initial and final STO at the same time. In contrast to the conventional surgical-orthodontic treatment protocol that includes preoperative orthodontics for dental decompensations to maximize stable postoperative occlusion, the SFA potentially shortens the treatment period and minimizes esthetic concerns during the decompensation period because skeletal problems are corrected from the beginning. The indications for the SFA have been proposed in the literature, but no consensus exists. Moreover, because dental occlusion of the pre-orthodontic arches cannot be used as a guide for establishing the surgical treatment plan, there are fundamental limitations in accurate prediction of postsurgical results in the SFA. Recently, the concepts of postsurgical orthodontic treatment are continuously changing and evolving to overcome this inherent limitation of the SFA. The elimination of presurgical orthodontics can change the paradigm of orthognathic surgery but still requires cautious case selection and thorough discussion and collaboration between orthodontists and surgeons regarding the goals and postoperative management of the orthognathic procedure.

• CELLMED
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• v.7 no.3
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• pp.12.1-12.6
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• 2017

The purpose of this study was to analyze the effect wool in patients with chronic obstructive pulmonary disease. The study was conducted experimentally on 53 patients with chronic obstructive pulmonary disease attending the chest diseases polyclinic of a hospital located in Erzurum. A randomized selection method was used to categorize patients into two groups; a treatment (n = 27), and a control group (n = 26). Patients in the treatment group (pre-test measurements were taken) wore wool vests for a period of three months, while patients in the control group wore cotton vests (placebo) for the same duration; post-test measurements were taken for both groups at the end of the three-month period. The Medical Outcomes Study Short Form 36, the St. George's Respiratory Questionnaire, and pulmonary function tests were used to collect data. Results concluded that there was a significant decrease (p < 0.05) in the overall score of the St. George's Respiratory Questionnaire, and the symptom, effect, and activity mean scores, while there was a significant increase (p < 0.05) in the SF-36 physical functioning, general health, bodily pain, role physical, vitality, role emotional, social functioning, mental health, physical and mental component summary mean scores of patients in the treatment group. Results of the study concluded that the symptoms, activity, disease effectiveness, and quality of life improved in patients that wore wool vests.

• Biomolecules & Therapeutics
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• v.8 no.3
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• pp.269-275
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• 2000

Silibinin(silybin) is the active component of silymarin from Silybum marianum and has hepato-protective effect. It is water-insoluble and has low bioavailability. To improve its bioavailability, self-micro-emulsifying drug delivery system (SMEDDS) has been developed by Hanmi Pharmaceutical Company (Silyma $n^{R}$ 140 soft capsule). In this study, the pharmacokinetic profiles of Silyma $n^{R}$ were examined and compared it with a reference preparation, L Caps140 of B Pharmaceutical Company. This study was approved by Yonsei University Severance Hospital IRB(approval No. CR0004) and followed the bioequivalence test guideline of Korean FDA. Eighteen healthy adult volunteers were allocated based on 2$\times$2 Latin square cross-over design. They were given 2 capsules (each contains silymarin 140 mg (60 mg as silibinin)) of either drug at each period and crossed over after a week of drug-free washout period. Blood concentration of silibinin was measured by HPLC. The $C_{max}$ and AUC of the Silyma $n^{R}$ were 1542.0 $\pm$ 402.7 ng/ml and 3323.3 $\pm$ 824.7 ng.h/ml, respectively, and were significantly higher than those of reference preparation. The Tmax was 0.8 $\pm$ 0.3 h and significantly shorter than reference preparation. The $K_{e}$ and $T_{1}$2/ of both drugs were comparable. Percent differences in means against reference preparation were +88.3% for AUC, +222.6% for $C_{max}$, and -61.1% for $T_{max}$./.>././.>./.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.10
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• pp.319-330
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• 2016

Recently, 3D printing technology has been applied to make a concept model and working mockup of an industrial application. On the other hand, this technology has limited applications in industrial products due to the materials and reliability of the 3D printed product. In this study, the components of a full cord switch module are proposed as a case of a 3D printed component that can be used as a substitute for a short period. These are hub-driven and lever lockup components that have the structural characteristics of breaking down frequently in the emergency operating status. To ensure the structural strength for a substitute period, research of structure optimization was performed because 3D printing technology has a limitation in the materials used. After optimizing the structure variables of the hub-driven component, reasonable results can be drawn in that the safety factors of the left and right switching mode are 1.243 (${\Delta}153.67%$) and 3.156 (${\Delta}404.96%$). The lever lockup component has a structural weak point that can break down easily on the lockup-part because of a cantilever shape and bending moment. The rib structure was applied to decrease the deflection. In addition, optimization of the structural variables was performed, showing a safety factor of 7.52(${\Delta}26%$).

• Journal of the Korean Society for Railway
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• v.20 no.5
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• pp.569-576
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• 2017

The electromagnetic valve of pneumatic doors of EMUs has a high failure rate due to air leakage because it supplies air on and off to operate the doors repeatedly. The electromagnetic valve is a very important safety component for which a very high reliability is required because failure makes it impossible to operate the passenger cars. However, domestic urban railway operators maintain electronic valves of the EMU door under a fixed cycle with a spare period according to the full overhaul cycle of the EMU. An improvement of the current maintenance cycle was suggested based on the reliability function and mission reliability. Using the statistical program MINITAB for the operational data of EMU line 6, we analyzed the characteristics of the fault distribution and derived the shape and scale parameters of the reliability function. If we limit the specific reliability probability to under a certain failure rate and calculate its statistical parameters, we can calculate the allowable inspection period with mission reliability. Through this study, we suggested a maintenance period based on RCM (reliability centered-maintenance) to improve the reliability of electromagnetic valves from 68% to 95%.

• Journal of Astronomy and Space Sciences
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• v.33 no.3
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• pp.185-196
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• 2016

New multiband BVRI light curves of NSVS 1461538 were obtained as a byproduct during the photometric observations of our program star PV Cas for three years from 2011 to 2013. The light curves indicate characteristics of a typical W-subtype W UMa eclipsing system, displaying a flat bottom at primary eclipse and the O'Connell effect, rather than those of an Algol/b Lyrae eclipsing variable classified by the northern sky variability survey (NSVS). A total of 35 times of minimum lights were determined from our observations (20 timings) and the SuperWASP measurements (15 ones). A period study with all the timings shows that the orbital period may vary in a sinusoidal manner with a period of about 5.6 yr and a small semi-amplitude of about 0.008 day. The cyclical period variation can be interpreted as a light-time effect due to a tertiary body with a minimum mass of 0.71 M_⊙. Simultaneous analysis of the multiband light curves using the 2003 version of the Wilson-Devinney binary model shows that NSVS 1461538 is a genuine W-subtype W UMa contact binary with the hotter primary component being less massive and the system shows a low mass ratio of q(m_c/m_h)=3.51, a high orbital inclination of 88.7°, a moderate fill-out factor of 30 %, and a temperature difference of ΔT=412 K. The O'Connell effect can be similarly explained by cool spots on either the hotter primary star or the cool secondary star. A small third-light corresponding to about 5 % and 2 % of the total systemic light in the B and V bandpasses, respectively, supports the third-body hypothesis proposed by the period study. Preliminary absolute dimensions of the system were derived and used to look into its evolutionary status with other W UMa binaries in the mass-radius and mass-luminosity diagrams. A possible evolution scenario of the system was also discussed in the context of the mass vs mass ratio diagram.

• Journal of electromagnetic engineering and science
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• v.3 no.2
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• pp.91-98
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• 2003

Software Communication Architecture(SCA) has been made to reduce the development period of new waveform applications by reusing design modules. Software Defined Radio(SDR) forum adopted SCA specification and follows its design concept. However, SCA specification does not describe interfaces and deployments of resources in details, which are software components, and how to implement them as well as how to communicate each other are another missing points in specification. In this paper, we propose a resource design methodology and details of adapter implementation for Core Framework(CF) that is a core set of open interface and services providing an abstraction of the underlying software and hardware layer. We also present SDR prototype system which communicates with resources implemented in different programming languages and processors in legacy environment through our design methodology.

• East Asian Economic Review
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• v.21 no.3
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• pp.201-230
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• 2017

This paper studies the long-run behavior of relative price dispersion among cities in Korea with a special emphasis on heterogeneous transitional patterns of price level dynamics. Formal statistical tests indicate considerable evidence for rejecting the null of relative price level convergence among the majority of cities over the sample period of 1985-2015. The analysis of gravity model suggests that the effect of transportation costs on intercity price level differentials is limited, while other socioeconomic factors, such as income, input factor prices, demographic structure, and housing price growth, play key roles in accounting for persistent regional price level disparities. Individual price levels are found to be better explained by a multiple-component model, and the deviations from PPP may be attributed to distinct stochastic common trends that are characterized by income and demographic structure.

• Journal of Astronomy and Space Sciences
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• v.1 no.1
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• pp.55-65
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• 1984

A total of 618 photoelectric observations (302 in yellow and 316 in bule) is made in 1982 at the Yonsei University Observatory. Except that of the secondary eclipse the homogeneous coverage of observations successfully secured B, V, and B-V light curves. Enhanced distortions in the light curves are appeared at the phases aroung $0.^P1$, which supports the wave-like migration period of 9.7 years(Rodono 1981). One epoch time of the primary minimum was made by combining the observations in three nights. This minimum time shows that the O-C values are still decreasing and there seems to indication of increasing. B and V light curves of the primary minimum are in strong asymmetry which show less luminous in the third and fourth contacts compared to those of the first and second ones. This asymmetry may be as a result of the reflection of the wave minimum at $0.^P1$, and B-V curve also shows asymmetry, redder at the third contact than the second one by about $0.^m04$. This color difference apperature distribution on the surface of cooler, larger component(KO IV star).

• Journal of Electrical Engineering and Technology
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• v.12 no.4
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• pp.1627-1633
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• 2017

This paper proposes a voice enhancing ear-protection system which is based on feedback active noise control(FBANC). The proposed system selectively suppresses the background noise and preserves the talking voice by controlling the adaptive algorithm with the voice activity period detection module. The noise reduction performance of the proposed noise canceling algorithm is analytically derived for the two key performance affecting parameters, i.e., electro-acoustic coupling distance and noise bandwidth. The proposed system is also implemented with a floating-point DSP system and its performance is experimentally tested to compare with the analytically derived results. The achieved levels of noise reduction for the three different noise bandwidths cases, i.e., 10Hz, 50Hz, and 90Hz, are high to show 17.05dB, 10.54dB and 8.99dB, respectively. The feasibility of the proposed system is also shown by the peak noise reduction achieved more than 25dB while preserving the voice component in the frequency range between 200-800Hz.