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The impact of COVID-19 on trauma patients and orthopedic trauma operations at a single focused training center for trauma in Korea

  • Choi, Wonseok;Kim, Hanju;Son, Whee Sung;Sakong, Seungyeob;Cho, Jun-Min;Choi, Nak-Jun;Noh, Tae-Wook;Kim, Namryeol;Cho, Jae-Woo;Oh, Jong-Keon
    • Journal of Trauma and Injury
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    • v.35 no.3
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    • pp.195-201
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    • 2022
  • Purpose: The objective of this study was to determine the effects of coronavirus disease 2019 (COVID-19) on the volume of trauma patients, the number of orthopedic trauma operations, and the severity of injuries. We also investigated the correlations between social distancing and these variables. Methods: This was a retrospective review of trauma patient cases at a single focused training center for trauma in Korea from January 2017 to April 2021. The COVID-19 group included patients treated from January 1 to April 30 in 2020 and 2021, and the control group included patients treated during the same months from 2017 to 2019. The volume of trauma patients according to the level of social distancing was evaluated among patients treated from August 2, 2020 to November 23, 2020. Results: The study included 3,032 patients who presented to the emergency department with traumatic injuries from January to April 2017 to 2021. The average number of patients was 646.7 and 546.0 in the control and COVID-19 groups, respectively. The percentage of patients injured in traffic accidents (TAs) decreased from 25.0% to 18.2% (P<0.0001). The proportions of in-car TAs and pedestrian TAs also decreased from 6.7% and 10.8% to 3.5% and 6.0%, respectively (P=0.0002 and P<0.0001). The percentage of bicycle TAs increased from 2.4% to 4.0% (P=0.0128). The proportion of patients with an Injury Severity Score above 15 and the mortality rate did not change significantly. As the level of social distancing increased, the number of trauma patients and the number of trauma injuries from TAs decreased. The number of orthopedic trauma operations also depended on the social distancing level. Conclusions: The number of trauma patients presenting to the emergency department decreased during the COVID-19 period. The volume of trauma patients and orthopedic trauma operations decreased as the social distance level increased.

Effects of Acupuncture with a Combination of GV20 and EX-HN1 Acupoints on CO2 Reactivity in the Anterior and Middle Cerebral Arteries during Hypercapnia in Normal Subjects: A Randomized Crossover Trial

  • Park, Hojung;Moon, Sang-Kwan;Lee, Han-Gyul;Kwon, Seungwon;Cho, Seung-Yeon;Park, Seong-Uk;Jung, Woo-sang;Park, Jung-Mi;Ko, Chang-Nam;Cho, Ki-Ho
    • The Journal of Internal Korean Medicine
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    • v.43 no.4
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    • pp.582-595
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    • 2022
  • Objectives: To investigate the effects of acupuncture at GV20 and EX-HN1 on cerebral blood flow (CBF) velocity and cerebrovascular reactivity (CVR) in the middle cerebral arteries (MCA) and anterior cerebral arteries (ACA) and to compare the effects to acupuncture at GV20. Methods: The study was a randomized, crossover trial that included 10 healthy men aged 20 to 29 years who underwent acupuncture treatment four times with a washout period of one week. The CBF velocity and CVR were measured by transcranial Doppler sonography (TCD) on both MCAs at the first and second visits, and both ACAs at the third and fourth visits. Participants were randomly assigned to one of two groups (A and B) before the first and third visits. Group A received two phases of acupuncture intervention at a single GV20 point and a combination of GV20 and EX-HN1 acupoints. Group B received the same interventions, but in the reverse order. Results: The increase in CO2 reactivity was significantly higher for the combination acupoints of GV20 and EX-HN1 than for the GV20 single acupoint in both MCAs (Right: 136 to 178, p=0.017; Left: 127 to 191, p=0.017) and ACAs (Right: 133 to 158, p=0.013; Left: 122 to 168, p=0.025). No significant change was noted in the corrected velocity at PETCO2 40 mmHg, blood pressure, or heart rate. Conclusions: The findings suggest that improvement of the CBF in the MCA and ACA after GV20 acupuncture increases when acupuncture is also performed at EX-HN1. These results clinically support the combined use of EX-HN1 and GV20 to treat disorders of MCA and ACA circulation.

Prediction of Change in Growth Rate of Algae in Jinhae Bay due to Cooling Water Discharge (냉배수 방류에 따른 진해만의 해조류 성장 속도 변화 예측)

  • Park, Seongsik;Yoon, Seokjin;Lee, In-Cheol;Kim, Byeong Kuk;Kim, Kyunghoi
    • Journal of the Korean Society of Marine Environment & Safety
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    • v.27 no.2
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    • pp.308-323
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    • 2021
  • In this study, we aimed to evaluate the environmental changes in Jinhae Bay caused by cooling water using numerical modeling. Cooling water discharge volume from the results of Case 1 (10 m3 sec-1) showed that the environmental changes in Jinhae Bay were extremely insignificant throughout the study period. In the simulation conditions of Case 2 (100 m3 sec-1), there was a decrease in water temperature of approximately 1 - 3℃ within a 5 km radius from the discharge outlet. In Case 3 (1000 m3 sec-1), a decrease in water temperature of up to 4 - 5℃ was observed within a radius of 8 km from the discharge outlet and cooling water discharge spread throughout the Bay. Growth rate of microalgae decreased by up to 15 % in November, whereas it increased by up to 6 % near the Hangam Bay in Case 3. From the above results, we confirmed that the environmental changes in Jinhae Bay due to cooling water discharged from Tongyeong LNG station are extremely insignificant. Moreover, it is expected that cooling water discharge could be utilized as a counter measure for 'red tide bloom' or 'macroalgae growth'.

A Study on the Supporting System for Growth Stage of Startup (창업기업의 성장단계별 지원체계에 관한 연구: 국내외 유니콘 기업의 사례 비교)

  • Lee, Jae-Seok;Lee, Ki-Ho;Lee, Sang-Myung
    • Korean small business review
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    • v.43 no.1
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    • pp.165-186
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    • 2021
  • Startups are undergoing a change throughout the growth process of startups that appear in existing studies as they move away from the existing B2B or B2C frame and expand their target customer groups to O2O, C2C. In this regard, a new type of startup known as unicorns, a unicorn which has grown rapidly in a short period of time, is being created by successfully attracting government support and external investment in recognition of the potential value of the startup. This study examined the relationship between investment attraction and growth after founding for five representative unicorns in the U.S. and Korea. As a result, it was found that private investment in Korea is passive and defensive, and is attracted after the Series A stage, compared to the U.S., where the growth potential of the startup ecosystem is positively evaluated. In addition, it found that government's support policy throughout the startup's growth process is an abstract and comprehensive policy focusing on initial funding for startups. Therefore, it was suggested that the scope of government policies should be expanded to forster startups as unicorns, and that it is necessary to establish and implement differentiated support policies for each growth of the scale-up of startups. This study is significant in that it presented the criteria for the growth stage and support of startups as well as policy support for scale-up through practical case analysis of unicorns.

The Effects of Coordinative Locomotor Training Program for Life-Care Promotion on Balance of Obese Elderly Women (라이프케어 증진을 위한 협응적 이동훈련 프로그램이 비만 여성노인의 균형에 미치는 영향)

  • Lee, Dong-Ryul
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.1
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    • pp.17-25
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    • 2020
  • The purpose of this study was to examine the effects of coordinative locomotor training (CLT) program on the balance for the promotion of life care of elderly obese women. Ten participants of elderly obese women who were able to walk independently without surgery experience of lumbar, hip or knee joint within the past year were recruited and under went the pretest, CLT (20 sessions), followed by the post-test. The test included BMI test using In-body, joint kinematics using myoVIDEO, muscle activation using surface EMG test (erector spinae (ER), external oblique abdominalis (EO), quadriceps femoris (Quad), hamstring muscle (Ham)) and balance tests including dynamic balance test using forced treadmill, Berg balance scale (BBS) and timed up go (TUG). The CLT program was conducted 60 minutes a day, 5 days a week, over 4 weeks period. As a result of this study, The the trunk and hip joints kinematics during the stance and swing phases of gait were a statistical significance levels were set at p <0.05. The ER and EO muscle activation were significantly improved after intervention (p <0.05). The length of gait line and single support line of change of center of pressure (COP) were significantly increased after intervention (p <0.05). The BBS and TUG were also significantly enhanced after intervention (p <0.05). The results of this study showed that CLT program for the improvement of life care had significant effects on improving postural instability, muscle weakness, reduced balance ability and falling risk of obese elderly women. Therefore, it is recommended to apply CLT program to improve life-care through improving balance ability and preventing fall of obese elderly women.

Improvement in Regional-Scale Seasonal Prediction of Agro-Climatic Indices Based on Surface Air Temperature over the United States Using Empirical Quantile Mapping (경험적 분위사상법을 이용한 미국 지표 기온 기반 농업기후지수의 지역 규모 계절 예측성 개선)

  • Chan-Yeong, Song;Joong-Bae, Ahn;Kyung-Do, Lee
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.24 no.4
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    • pp.201-217
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    • 2022
  • The United States is one of the largest producers of major crops such as wheat, maize, and soybeans, and is a major exporter of these crops. Therefore, it is important to estimate the crop production of the country in advance based on reliable long- term weather forecast information for stable crops supply and demand in Korea. The purpose of this study is to improve the seasonal predictability of the agro-climatic indices over the United States by using regional-scale daily temperature. For long-term numerical weather prediction, a dynamical downscaling is performed using Weather Research and Forecasting (WRF) model, a regional climate model. As the initial and lateral boundary conditions of WRF, the global hourly prediction data obtained from the Pusan National University Coupled General Circulation Model (PNU CGCM) are used. The integration of WRF is performed for 22 years (2000-2021) for period from June to December of each year. The empirical quantile mapping, one of the bias correction methods, is applied to the timeseries of downscaled daily mean, minimum, and maximum temperature to correct the model biases. The uncorrected and corrected datasets are referred WRF_UC and WRF_C, respectively in this study. The daily minimum (maximum) temperature obtained from WRF_UC presents warm (cold) biases over most of the United States, which can be attributed to the underestimated the low (high) temperature range. The results show that WRF_C simulates closer to the observed temperature than WRF_UC, which lead to improve the long- term predictability of the temperature- based agro-climatic indices.

Analysis on the Changes in Abandoned Paddy Wetlands as a Carbon Absorption Sources and Topographic Hydrological Environment (탄소흡수원으로서의 묵논습지 변화와 지형수문 환경 분석)

  • Miok, Park;Sungwon, Hong;Bonhak, Koo
    • Land and Housing Review
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    • v.14 no.1
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    • pp.83-97
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    • 2023
  • The study aims to provide an academic basis for the preservation and restoration of abandoned paddy wetland and the enhancement of its carbon accumulation function. First, the temporal change of the wetlands was analysed, and a typological classification system for wetlands was attempted with the goal of carbon reduction. The types of wetland were classified based on three variables: hydrological environment, vegetation, and carbon accumulation, with a special attention on the function of carbon accumulation. The types of abandoned paddy wetlands were classified into 12 categories based on hydrologic variables- either high or low levels of water inflow potential-, vegetation variables with either dominance of aquatic plants or terrestrial plants, and three carbon accumulation variables including organic matter production, soil organic carbon accumulation, and decomposition. It was found that the development period of abandoned paddy analyzed with aerial photographs provided by the National Geographic Information Institute happened between 2010 and 2015. In the case of the wetland in Daejeon 1 (DJMN01) farming stopped by 1990 and it appeared to be a similar structure to natural wetlands after 2010 . Over the past 40 years the abandoned paddy wetland changed to a high proportion of forests and agricultural lands. As time went by, such forests and agricultural lands tended to decrease rapidly and the lands were covered by artificial grass and other types of forests.

Distribution of mushrooms spontaneously growing in Naejangsan National Park (내장산국립공원의 자생버섯 분포상)

  • Pyung-Yeol, Ko;Hye-Sung, Park;Seung-Hak, Lee;Yong-Chull, Jeun
    • Journal of Mushroom
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    • v.20 no.4
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    • pp.208-217
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    • 2022
  • Mushrooms in Naejangsan National Park between May and September of 2021 have been surveyed. In this period, a total of 4 divisions, 9 classes, 25 orders, 72 families, 171 genera, and 381 species, including 3 climate-sensitive biological indicator species were found. The order in which the most diverse array of species was observed is Agaricales, which includes 24 families, 64 genera, and 170 species. Among these, the genus Russula was dominant, with 30 species, followed by the genus Amanita with 27 species. Among the 12 grids we investigated, species diversity was greatest in grid F5, in which 56 species of mushrooms were found. In particular, a large number of ectomycorrhizal mushrooms, including Russula spp. and Lactarius spp. were recognized. We presume that the gentle slopes and the low occurrence of Sasa borealis in this area may create a favorable environment for wild mushrooms. In corroboration, some grids (e.g. F6, F8, and F10) covering steep slopes and harboring large numbers of Sasa borealis contained only 19 species. Based on DNA sequence analysis, the NJ21064 was identified as Chlorophyllum hortense, which is newly recorded in Korea.

A Randomized, Double-blind, Placebo-controlled Study to the efficacy and Safety of NMED-01 and NMED-02 in Mild Alcoholic Liver Subjects (NMED-01과 NMED-02의 간기능 개선에 대한 인체 효능 평가)

  • Park, Sangwoug;Kwon, Yongbeom;Kim, Ki Tae;Shin, Seon Mi;Leem, Kang-Hyun;Ko, Heung;Song, MiKyung;Jung, Yoon Chul;Kim, Hocheol;Park, Juyeon
    • The Korea Journal of Herbology
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    • v.28 no.6
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    • pp.31-38
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    • 2013
  • Objectives : The purpose of this study was to determine whether NMED-01 or NMED-02 improves laboratory test results in participants with liver function disorder. Methods : This is a randomized, placebo-controlled trial in which participants, treating physicians and data management staff were blinded to treatment group. The study was conducted at Semyung university oriental medicine hospital in Jecheon where participants with high level of serum ${\gamma}$-GTP (60-350 U/L) were enrolled. The intervention consisted of three times daily ingestion of either two capsules of placebo, NMED-01 (NeuMed. co. ltd., Seoul), or NMED-02 (NeuMed. co. ltd., Seoul) for twelve weeks. To evaluate the efficacy and safety of NMED-01 and NMED-02, we primarily evaluated the degree of decrement of serum ${\gamma}$-GPT level among three groups. Secondarily the decrement of serum ALT, AST, and triglyceride level in each group were also evaluated. Adverse effects were monitored during the twelve weeks treatment. Results : The change of ${\gamma}$-GTP level of NMED-01 group was lower than that of placebo group at the end of 12-week administration ($28.1{\pm}38.7U/L$ vs. $9.3{\pm}27.0U/L$, p=0.046). Other variables including AST, ALT, and triglyceride level were not significantly reduced. The decrement of ${\gamma}$-GPT, AST, ALT, and triglyceride level of NMED-02 group was not significant. There were no significant adverse effects or toxicities during treatment period. Conclusions : Participants receiving NMED-01 had improvement in laboratory test results. Despite a modest sample size, our results suggest that NMED-01 are safe and may be potentially effective in improving liver function. However, NMED-02 have lack of a detectable effect in this study.

Comparative Evaluation of Korean Medicine Well-matched with Pork through an Inhibition of Pancreatic Lipase (저육(猪肉)과 잘 어울리는 췌장라이페이즈 억제능을 가진 한약재의 비교평가)

  • Shin, Mi-Rae;Kim, SooHyun;Lee, AhReum;Kim, KyeongJo;Kim, SuJi;Lee, Young Cheol;Roh, Seong-Soo
    • The Korea Journal of Herbology
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    • v.32 no.5
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    • pp.57-63
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    • 2017
  • Objectives : The aim of this study is to search Korean Medicine with the superior inhibitory effect of pancreatic lipase including a possibility as a well-matched sauce material with pork. Methods : We chose 5 samples which have the potent inhibitory effect of pancreatic lipase enzyme among 9 samples. 5 samples were Glycyrrhizae rhizoma, Cinnamomi cortex, Ganoderma lucidum, Syzygium aromaticum, and Schisandra chinensis. Animals were divided into eight groups (n=7). The experimental groups except for normal group were fed 60% high-fat diet. 5 samples were orally administered at a dose of 200 mg/kg body weight and orlistat were orally administrated at a dose of 60 mg/kg body weight for 7 days. Biochemical anaylses of 5 samples were executed based on lipid parameters such as triglyceride (TG) and total cholesterol (TC). Results : Korean Medicines with $IC_{50}$ of below $1mg/m{\ell}$ were Glycyrrhizae rhizoma, Cinnamomi cortex, Ganoderma lucidum, Syzygium aromaticum, and Schisandra chinensis. Body weight change of all drug-treated groups except Glycyrrhizae rhizoma reduced significantly during the experimental period. Orlistat treatment reduced significantly both TG and TC in serum. The significant emission of TG in fece showed in Cinnamomi cortex treatment, whereas Ganoderma lucidum and Syzygium aromaticum showed a tendency to increase without a significance. Besides, Ganoderma lucidum and Schisandra chinensis emitted significantly TC to fece. Conclusions : In conclusion, Cinnamomi cortex may exert anti-obesity effect by directly inhibiting pancreatic lipase, which would prevent the absorption of lipid from the small intestine. Accordingly, Cinnamomi cortex may suggest a high possibility as a well-matched sauce material with pork.