• 대한한의학방제학회지
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• 제27권1호
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• pp.65-71
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• 2019

Objective : This study aims to diversify interpretation of formulas from "Onbyungjobyun" by analyzing various formulas from "Onbyungjobyun" as basic formulas. Method : This study found herbal communities of combination by analyzing herbal combinations based on network analysis of formulas from "Onbyungjobyun", and has analyzed each community of combination as basic formulas. Result : The results of network analysis showed a total of 3 herbal communities of combination; first was medicinal herbs from Eungyo-san(銀翹散), Jeungaek-tang(增液湯), Bokmaek-tang(復脈湯), Gyeji-tang(桂枝湯), Sogeonjung-tang (小建中湯) series; second was medicinal herbs from Angungwoohwang-hwan(安宮牛黃丸); third was medicinal herbs from Baekho-tang(白虎湯), Jaseol-dan(紫雪丹), Sayeok-tang(四逆湯) series. Conclusion : The formulas from "Onbyungjobyun" are consisted of herbal communities of combination; that treat warm-heat pathogen and supplies yin essence or yang qi; treat reverse transmission to the pericardium(逆傳心包); and treat heat in the qi phase in Onbyeong and cold-dampness in the middle energizer.

• 대한한의학원전학회지
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• 제36권1호
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• pp.17-32
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• 2023

Objectives : This paper investigates the background, meaning and origin of the descriptions of the Heart such as 'seven orifices', 'sanmao', 'saw-toothed four layered lines' that are unique to the diagram in the Donguibogam. Methods : First the Heart diagram of the Donguibogam was compared with other Zhangfu diagrams of the past. Materials related to unique features in the descriptions of the Heart in the Donguibogam were collected, against which descriptive features were analyzed. Results : Of the many unique features, the descriptive basis of the 'seven orifices' could be found in the Qixingban[七星板] as a physical entity reflecting basic anatomical knowledge. The 'sanmao', which is compared to the Santaixing[三台星], could be understood as a non-physical entity whose descriptive basis could be found in the Xinxuetu of the Xinching. It could be assumed that the 'saw-toothed four layered lines' are likened to the multi-layered petals or calyx of a lotus flower bud to describe the Pericardium, or to the multiple walls of a mountain fortress surrounding a palace to describe the Danzhong, which is the chest cavity. These features could be understood as results of spiritualism influence. Conclusions : It could be concluded that Heo Jun, in his attempt to describe the Heart in more detail than previous diagrams of the Zangfu, referenced popular texts and images based on anatomical knowledge of previous texts, added varied descriptions resulting in a new diagram with a completely different origin.

• Asian Pacific Journal of Cancer Prevention
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• 제13권11호
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• pp.5735-5739
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• 2012

Background: Malignant mesothelioma (MM) is an insidious tumor with poor prognosis, arising from mesothelial surfaces such as pleura, peritoneum and pericardium. We here aimed to evaluate the demographic, clinical, and radiological features of patients with MM followed in our center as well as their survival. Methods: The study included 228 patients (131 male, 97 female) who were followed up in our institution between 1993 and 2010 with the diagnosis of MM. Results: The mean age was 59.1 years in men and 58.7 years in women and the sex ratio was 1.4:1 in favor of males. Environmental asbestos exposure was present in 86% of the patients for a mean duration of $40{\pm}20$ years (range: 3-70). Pleural effusion and thoracic/abdominal pain were the most common presenting signs and symptoms (70.2% and 57.8%, respectively). One hundred-thirteen (66%) patients were treated with platinum-based combination chemotherapy (PBCT) plus supportive care (SC) and 67 (34%) patients received SC alone. The median follow-up time was 10.0 months. The median overall survival was significantly improved with PBCT plus SC compared to SC alone (11.4 vs. 5.1 months; p=0.005). The 6, 12, 18, and 24-month survival rates were significantly improved with PBCT plus SC compared to SC alone (72%, 43%, 19%, and 2% vs. 49%, 31%, 11%, and 1%). Conclusion: The survival of patients with MM improved in patients treated with PBCT. The survival advantage continued 12- and 24-month after the initial time of combination chemotherapy.

• Tuberculosis and Respiratory Diseases
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• 제61권4호
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• pp.398-402
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• 2006

저자들은 하지 부종과 통증을 주소로 내원한 환자에서 심부 정맥혈전증과 폐암이 있는 환자를 경험하였기에 혈전의 유발 원인이 없는 환자에서 발생하는 특발성 혈전증 환자에서 잠재적 종양에 대한 주의 관찰이 필요할 것으로 보여 문헌 고찰과 함께 더불어 보고하는 바이다.

• 동의신경정신과학회지
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• 제12권2호
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• pp.37-51
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• 2001

The clinical study was carried out the 43 patients with Depression who were treated in Department of Neuropsychiatry, College of Oriental Medicine, Dae Jeon University from 22 February 2000 to 14 November 2001. The results were summarized as follows. 1. The ratio of male and female was 10:33, 60's(32.6%) was frequent, no inducing factor(38.3%) was seen in a lot of cases and many patients came to our hospital by way of west-neuropsychiatry(56.8%). 2. The period of clinical history was frequent from 3 to 10 years(23.2%), the most frequent preceding disease was cardiovascular systemic disease(18.4%). 3. The main clinical symptoms were apprehension alpitation(13.4%), anorexia(9.8%), headache nuchal region stiffness(9.8%), general body weakness(6.5%), chest discomfort(6.5%), dizziness(5.7%), febris(5.3%) and constipation(5.3%). 4. The patient's tongue aspect had pink tongue and empty fur(32.6%) and pulse type had thin and deficient pulse(39.5%). The prescription drugs were Chunggansoyo-san(30.0%), purging liver and alleviating depression to regulate qi, and Guibiondam-tang(15.8%) eliminating phlegm, cooling pericardium and warming gallbladder. 5. The curve was within normal range at Psychoneural system(81.4%), and Visceral system(90.1%). 6. The regulation was Normal(48.1%), RL(27.9%), RR(20.2%) at Psychoneural system and Normal(45.9%), RL(28.5%), RR(20.3%) at Visceral system. 7. Activity and Reactivity had much lower response at 1th, 2th, 3th, 4th, 7th SANGHAN, Polalization had much higher response at 1th, 4th, SANGHAN and much lower response at 2th, 3th, 7th SANGHAN.

• Journal of Chest Surgery
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• 제10권2호
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• pp.315-326
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• 1977

From 1958 to October 1977, 294 cases of acquired heart disease were operated. There were 68 cases of pericardium, 3 trauma, 2 foreign body, one cardiac thrombus, 3 atrial myxoma, 2 left atrial and 1 right atrial, 2 Budd-Chiari syndrome, and 214 valvular heart disease. Out of 214 cases of valve operation 73 valves were replaced in 64 patients. Male to female ratio was 1.46: 1. The youngest age was 14 years in male and 18 in female. The oldest was 54 years in male and 52 in female. Fifty-five cases of single valve were replaced, consisting of 47 mitral and 8 aortic valves. There were 9 double valve replacement cases which consist of 7 mitral and aortic and 2 mitral .and tricuspid valves. Six varieties of prosthetic valves, 3 ball and 3 disc types and 3 kinds of xenograft tissue valves were utilized. Beall, BjSrk-Shiley and Starr-Edwards prosthetic valves and Hancock valves were used mainly. For single valve 34. 5% and for double valve replacement 44% mortality were noted. There were 23 operative deaths out of 64 patients, over all mortality rate of 36.9%. Mortality for mitral valve replacement was 29.5%. But in recent 12 consecutive cases one death occurred, showing 8.3% mortality. In earlier days thrombocyte anti-adhesive drug dipyramidole-persantin-aspirin and/or SP 54 were adminstered. But in recent cases after heparinization, coumadin and Persantin were prescribed routinely.

• Journal of Chest Surgery
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• 제32권7호
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• pp.665-667
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• 1999

좌관상 동맥동에서 발생하여 좌심실로 파열된 발살바동 동맥류에 기인한 울혈성 심부전을 주소로 내원한 48세 남자 환자의 수술적 체험 1례를 보고 하고자 한다. 술 전 심 초 싣캥\ulcorner좌 관상동맥동에서 시작하여 좌 심실에 이르는 머리핀 모양의 낭(sac)이 관찰 되는 발살바동 동맥류의 파열이 관찰되었고, 대동맥 좌심실 터 널(aorto-left ventricle tunnel)을 감별 진단에 범주에 두었다. 수술 소견상 좌 관상동맥동에서 시작하여 좌심실 내의 승모판 전엽 하방에 여러개의 누공을 보이는 직경 7mm, 길이 20mm의 동맥류가 관찰되었다. 수술은 파 열동맥류의 대동맥측 근위부는 우심낭으로 첨포봉합 하였고, 좌심실내의 원위부는 spaghetti를 이용해 직접 봉합하였다. 환자는 술 후 14일째 퇴원하였고, 술 후 8개월 동안 별다른 문제없이 외래 추적 관찰 중이다. 이에 저자들은 본 질환의 희귀성과 함께 수술적 방법을 알리고자 증례 보고 하는 바이다.

• Journal of Chest Surgery
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• 제32권7호
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• pp.675-680
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• 1999

소아의 흉부기관협착증 2례에 대해 자가심막을 이용해 전방 기관성형술을 실시\ulcorner였다. 증례 1은 9세된 여 아에서 발견된 선천성 기관협착증의 경우로 인공폐의 보조 아래 기관성형과 동반된 좌폐동맥 기시이상을 동 시에 근치하였다. 환아는 이식된 심막편이 종격조직에 고정될 때까지 수술 후 10일 간 기계호흡을 실시하였 다. 증례 2는 8세된 남아에서 기관절개술 후 하부기관협착이 발생한 경우로, 심막편 바깥을 늑연골편으로 보 강함으로써 수술 직후 기도삽관을 제거할 수 있었다. 2례 모두 수술 후 1년 이상의 관찰기간 동안 기관내경 이 잘 유지되고 있으며, 기관재건부위가 성장하는 소견을 보인다.

• Journal of Chest Surgery
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• 제36권12호
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• pp.979-984
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• 2003

원발성 폐동맥 육종은 매우 드문 질환이다. 임상증상과 방사선학적 소견이 폐동맥 색전증과 유사하기 때문에 진단 시 폐동맥 색전증으로 오진되는 예가 빈번하고, 본 질환의 빠른 진행속도로 인하여, 사망 후 부검을 통해 확인되는 예도 있다. 따라서 폐동맥 색전증으로 진단된 환자가 혈전의 원발병소가 불분명하면서 항응고제에 반응하지 않는다면, 원발성 폐동맥 육종을 의심해 보아야 한다. 폐동맥 색전증으로 진단받은 57세 남자 환자가 5개월간의 항응고제 치료 후에도 우측폐의 종괴모양 병변이 증가하고 주폐동맥 색전증의 크기가 증가되어 수술적인 치료과정에서 폐동맥 내막육종(Pulmonary artery intimal sarcoma)으로 확인되었다. 수술전 혈전으로 의심되었던 저음영의 종괴는 동결조직검사 상 폐동맥 육종으로 의심되었으며, 심낭에 침윤이 있었다. 그 병변과 독립적으로 우폐동맥과 폐실질에서도 혈관육종이 발견되었으며, 인공심폐기하에서 주폐동맥의 완전 절제술 시행 후 Gore-tex graft 치환술과 우측 전폐절제술을 시행하였다. 수술 후 2차례의 항암치료를 시행한 후에 퇴원하였다.

• Journal of Chest Surgery
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• 제30권2호
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• pp.200-204
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• 1997

본 증례는 고유 대동맥 판막, 승모판막, 삼첨판막과 심실중격을 침 범한 심내막염환자의 성공적 치료에 대한 보고이다. 환자는 11세때 심실중격결손폐쇄와 대동맥판막성형술을 받은 16세 남아로서 심내막염으로 항생제치료에도 불구하고 난치성 심부전을 보였다. 수술소견상 이전 수술시 폐쇄한 심실중격폐쇄를 따라 커다란 결손을 보였으며 다발성 천공과 우종을 동반한 대동맥 판막역류, 우종을 동반한 승모판 역류, 대동맥 판륜주위농양, 심실중격의 심근농양, 천공과 우종을 동반한 삼첨 판역류 소견을 보였다. 수술은 모든 감염조직과 괴사조직을 근치적절제후 심실중격결손을 Dacron patch로 폐쇄하면서 대동맥판막륜부위까지 확장보강하였으며, 대동맥판막치환시 확장보강한 Patch에 인공판막을 거치시켜 안전하게 치환할 수 있었다. 승모판막은 치환하였고, 삼첨 판은 자가심낭편으로 재건하였다. 환자는 수술후 6주간 항생제치료후 다른 합병증 없이 건강한 상태로 퇴원하였다.