• Journal of Korean Neurosurgical Society
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• v.30 no.9
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• pp.1108-1114
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• 2001

Objective : Prognostic factors of metastatic brain tumors have been widely reported and their operative indications also have been extended gradually even to the poor grade patients. Authors intended to analyze the causative factors for the clinical outcome of metastatic brain tumors, especially with relevant to the poor prognosis by one year follow-up evaluation. Patients and Methods : The authors retrospectively studied the clinical characteristics of 46 cases(35 patients) with metastatic brain tumors among 466 cases(437 patients) which were operated on due to the brain tumor, during the period between January 1994 to June 1999. Statistical analysis was performed by using SPSS 8.0$^{(R)}$. A p-value of less than 0.05 was considered clinically significant. Result : Among the variable clinical factors in patients with metastatic brain tumors, Karnofsky Performance Scale (KPS) score of less than 70(16 patients), uncontrolled primary tumor(8 patients), and surgical resection without further adjuvant therapy(9 patients) showed statistically significant poor prognosis ; p value of 0.002, 0.032, and 0.001, respectively. Other tested variables, such as old age(greater than 65 years ; 10 patients), gender(male ; 20 patients), type of primary cancer(primary undefined ; 6 patients, lung cancer ; 15 patients), location(infratentorial ; 9 patients, sellar ; 5 patients), number of lesion(multiple ; 12 patients), and number of operation(multiple craniotomy ; 7 patients) were not related to the poor prognosis. Conclusions : The most common primary site of distant metastasis was lung. The poorer prognosis was highly correlated with various factors including low KPS score(<70), no postoperative adjuvant therapy, and uncontrolled primary tumors.

• Journal of Korean Neurosurgical Society
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• v.59 no.4
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• pp.392-399
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• 2016

Objective : Brain metastases in gynecologic cancer (ovarian, endometrial, and cervical cancer) patients are rare, and the efficacy of Gamma Knife Radiosurgery (GKRS) to treat these had not been evaluated. We assessed the efficacy of GKRS and prognostic factors for tumor control and survival in brain metastasis from gynecologic cancers. Methods : This retrospective study was approved by the institutional review board. From May 1995 to October 2012, 26 women (mean age 51.3 years, range 27-70 years) with metastatic brain tumors from gynecologic cancer were treated with GKRS. We reviewed their outcomes, radiological responses, and clinical status. Results : In total 24 patients (59 lesions) were available for follow-up imaging. The median follow-up time was 9 months. The mean treated tumor volume at the time of GKRS was $8185mm^3$ (range $10-19500mm^3$), and the median dose delivered to the tumor margin was 25 Gy (range, 10-30 Gy). A local tumor control rate was 89.8% (53 of 59 tumors). The median overall survival was 9.5 months after GKRS (range, 1-102 months). Age-associated multivariate analysis indicated that the Karnofsky performance status (KPS), the recursive partitioning analysis (RPA) classification, and the number of treated lesions were significant prognostic factors for overall survival (HR=0.162, p=0.008, HR=0.107, p=0.038, and HR=2.897, p=0.045, respectively). Conclusion : GKRS is safe and effective for the management of brain metastasis from gynecologic cancers. The clinical status of the patient is important in determining the overall survival time.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.19 no.10
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• pp.2457-2464
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• 2015

Distributed Networked Control Systems (NCSs) through wireless networks have a tremendous potential to improve the efficiency of various control systems. In this paper, we define the State Update Interval (SUI) as the elapsed time between successful state vector reports derived from the NCSs. A simple expression of the SUI is derived to characterize the key interactions between the control and communication layers. This performance measure is used to formulate a novel optimization problem where the objective function is the probability to meet the SUI constraint and the decision parameter is the channel access probability. We prove the existence and uniqueness of the optimal channel access probability of the optimization problem. Furthermore, the optimal channel access probability for NCSs is lower than the channel access probability to maximize the throughput. Numerical results indicate that the improvement of the success probability to meet the SUI constraint using the optimal channel access probability increases as the number of nodes increases with respect to that using the channel access probability to maximize the throughput.

• Journal of Navigation and Port Research
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• v.33 no.10
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• pp.735-742
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• 2009

Information security is an essential factor that enables terminal to be operated. However, despite of this importance of information security, there has hardly been any research related to this topic. And moreover, current level of information security performance in container terminals has not been analyzed so far. The objective of this study is to evaluate current level of information security in container terminals. Through survey from the four leading container terminal operators in Korea, The results firstly showed that average of information security level of major container terminals was 71.7%. And from the results of data analysis, it revealed that the weak point of information security in Korean container terminals was security management, and in detail, lack of expertise of support group.

• Journal of Broadcast Engineering
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• v.18 no.2
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• pp.167-177
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• 2013

In this paper, a motion adaptive deinterlacing algorithm is proposed. It consists of three parts: (1) modified edge-based line average, (2) pixel-based consequent five-field motion detection, and (3) block-based local characteristic for detecting true motion and calculating the motion intensity by using an improved method which is able to detect the inner part of moving objects precisely as well as to reduce the risk of false detection caused by intrinsic noises in the image. Depending on the detected motion activity level, it combines spatial and temporal methods with weighting factor. Simulations conducted on several video sequences indicate that the performance of the proposed method is superior to the conventional methods in terms of both subjective and objective video quality.

• Korean Journal of Biological Psychiatry
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• v.8 no.2
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• pp.266-270
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• 2001

Objective : The purpose of this study was to compare the plasma amitriptyline and nortriptyline level between before and after fluoxetine addition with patients who were currently taking amitriptyline. Method : From the inpatient and outpatient unit of Soon Chun Hyang University Hospital, Chunan, fourteen subjects who were taking amitriptyline 25mg more than 1 week at least were given fluoxetine 20mg. Before and 2 weeks after fluoxetine addition, the plasma level of amitriptyline and nortriptyline are analyzed simultaneously by High Performance Liquid Chromatography(HPLC). At the same times, HAM-D(Hamilton Rating Scale for Depression) score and the UKU(Uldvalg for Klinske Unders${\Phi}$ gelser) side effect scale were checked. Results : After fluoxetine addition to the patients who were taking amitriptyline, the plasma level of amitriptyline, nortriptyline and sum of amitriptyline and nortriptyline had risen. The mean plasma amitriptyline level increased from $168.9{\pm}89.4ng/ml$ to $183.0{\pm}102.0ng/ml$ after fluoxetine addition(p=0.011), but the change was not statistically significant. The mean plasma nortriptyline level increased significantly from $114.3{\pm}70.2ng/ml$ to $168.0{\pm}86.2ng/ml$ after fluoxetine addition(p=0.011). In addition, the mean plasma level of total amitriptyline and nortriptyline increased significantly from $283.1{\pm}125.3ng/ml$ to $350.9{\pm}78.4ng/ml$ after fluoxetine addition(p=0.016). After fluoxetine addition, no significant change was noted in the UKU side effect scale score. Conclusion : As consequence of comparison of plasma amitriptyline and nortriptyline level before and after fluoxetine addition, mean amitriptyline, nortriptyline and total plasma level was increased after fluoxetine addition. This suggests that coadministration of amitriptyline and fluoxetine may induce improvement of depressive symptom in depressive patients by way of increased plasma level of amitriptyline.

• Journal of Advanced Marine Engineering and Technology
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• v.39 no.8
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• pp.843-848
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• 2015

The objective of this study is to observe and optimize a typical ocean environment and reduce wave reflections in the wave flume. In order to generate ocean waves in the wave flume, a combination of a horizontal piston type wave generator and wave absorbers was installed in the channel. Two probes for measuring the wave heights, i.e., wave level gauges, were used to record the continuous variation of the wave surface, the phase difference, and the maximum (crest) and minimum (trough) points of the propagating waves. In order to optimize the shape and size of the propagating waves, several absorption methods were proposed. Apart from an active wave absorption method, we used methods that involved vertical porous plates, horizontal punching plates, and sloping-wall-type wave absorbers. To obtain the best propagating waves, a sloping-wall-type wave absorber was chosen and tested in terms of the constitutive filling materials and the location and shape of the plate. This study also focused on the theoretical prediction of the wave surface, separating them into the incident and reflective components. From the results, it is evident that the wave absorber comprising a hard filling material exhibits a better performance than the absorber comprising a soft material, i.e., the wave absorber can be a strong sink to control the energy of the incoming wave. In addition, larger wave absorbers correspond to lower reflectance because a larger volume can reduce the incoming wave energy. Therefore, at constant absorber conditions, the reflectance of the wave increases as the wave period increases. Finally, the reflectance of the wave was controlled to be less than 0.1 in this study so that the wave flume can be used to simulate an offshore environment.

• Korean Journal of Oriental Medicine
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• v.13 no.3
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• pp.79-85
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• 2007

Objective : To investigate documented surveys about adverse events of acupuncture therapy. Methods: We searched Medline with the terms of 'acupuncture/adverse event(s)', 'acupuncture/side effect(s)' and 'CAM/adverse event(s)' using Pubmed and set the limits to human study. Results: There were 5 prospective studies, 3 reviews and 3 surveys in our searching. There were 3 reports about acupuncture related adverse events in UK ranging from 10.7% to 15% of which the rate of significant events were from 0.13% to 0.14%. In Germany, there were 11% of acupuncture related adverse events in one report and 7.5%(significant events were 45 in 190,924 patients) in another report. In Australia, one study reported that every adverse event associated with acupuncture occurred in 8-9 month per one practitioner. In Japan, 0.14% of acupuncture related adverse events in 48 practitioners were reported in one systemic review. A cumulative review about significant adverse events associated with acupuncture reported 715 adverse events of which most frequent accidents were pneumothorax and central nervous system injury. Conclusion : The risk of adverse event associated with acupuncture is far lower than that associated with other general medical interventions. However, some safety guidelines about the acupuncture performance are needed.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2006.11a
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• pp.548-553
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• 2006

Activity-based productivity data can be used as an significant reference in many areas of project management such as performance evaluation and project planning. However, the existence of various factors influencing construction productivity makes it difficult to collect and analyze the productivity data. In the most of the domestic construction sites, there is no systematic method to collect and analyze the productivity data along with information on influencing factors; it is common to heavily rely on experience and intuition of field managers when dealing with construction productivity data. Therefore it is necessary to develop a management system for collecting and utilizing the productivity data as well as the factors influencing construction productivity. The main objective of this research is to define the construction productivity and its influencing factors at the activity level. In addition, methodologies on how to analyze the productivity data and to estimate productivity of future projects are proposed.

• Proceedings of the Korean Institute Of Construction Engineering and Management
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• 2006.11a
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• pp.692-697
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• 2006

The importance about the maintenance consideration of the building has a great impact and regarding the life continuation of the building the many interest is becoming intensively. The housing lot of the heart of urban at the capital region has insufficient recently and the construction of the ground complex building in solution for the insufficiency is increasing at the rapid pace. The ground complex building is brings the maximization of land use from inside the site, but maintenance consideration phase is caused by administration cost share and administration bound limit where person is concerned for a many problem point it contains. The objective of the present paper is that the building is maintain an efficiency initially and is improve in order to develop guide line for a maintenance consideration improvement from design phase. According as literature research and question research is enforce, the paper is escape problem point the maintenance consideration and is bring up guide line for the architectural plan field and the maintenance consideration improvement of the building. Result of the study is expected a help in maintenance consideration improvement during life cycle of the building