• 제목/요약/키워드: peak effect

검색결과 3,466건 처리시간 0.031초

DNA와 Benzo(a)pyrene 대사물질 결합형성에 미치는 인삼 추출물의 영향 (Effect of Ginseng Extracts on the Binding to DNA of Benzo(a)pyrene Metabolites in uitro in Rats)

  • 박진규;고지훈
    • Journal of Ginseng Research
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    • 제13권1호
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    • pp.37-41
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    • 1989
  • Benzo(a)pyrene(BP)의 monooxygenase(AHH)에 의해서 생성된 반응성 대사물질들의 in vitro DNA와의 결합 및 BP 대사에 관여하는 효소들의 활성도에 미치는 인삼 물추출물의 영향을 조사하였으며, DNA-BP metabolite adduct들은 Sephadex LH-20 column으로 chromatography하여 5개의 major peak 들을 얻었다. 이 peak 들을 극성이 큰 순서대로 A부터 E까지 임의로 정하고 5개의 peak들을 7,8-diol-9,10-oxide(A), 7,8-oxide(B). 4,5-oxide(C), 9-HO-BP(D & E) adduct들로 잠정적으로 확인하였다. Peak A, C, D 그리고 E는 각각 대조군의 30, 15, 20 그리고 30%로 감소되었으며 peak B는 의미있는 변화를 보이지 않았다. DNA-BP 결합 억제와 관련하여 in vitro와 in vivo 투여시의 경향이 유사하여 EH의 활성도만 BP투여 대조군보다 38%정도 의미있게 유도되었다.

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Errors in light-emitting diodes positioning when curing bulk fill and incremental composites: impact on properties after aging

  • Abdulrahman A. Balhaddad;Isadora M. Garcia;Haifa Maktabi;Maria Salem Ibrahim;Qoot Alkhubaizi;Howard Strassler;Fabricio M. Collares;Mary Anne S. Melo
    • Restorative Dentistry and Endodontics
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    • 제46권4호
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    • pp.51.1-51.13
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    • 2021
  • Objectives: This study aimed to evaluate the effect of improper positioning single-peak and multi-peak lights on color change, microhardness of bottom and top, and surface topography of bulk fill and incremental composites after artificial aging for 1 year. Materials and Methods: Bulk fill and incremental composites were cured using multi-peak and single-peak light-emitting diode (LED) following 4 clinical conditions: (1) optimal condition (no angulation or tip displacement), (2) tip-displacement (2 mm), (3) slight tip angulation (α = 20°) and (4) moderate tip angulation (α = 35°). After 1-year of water aging, the specimens were analyzed for color changes (ΔE), Vickers hardness, surface topography (Ra, Rt, and Rv), and scanning electron microscopy. Results: For samples cured by single-peak LED, the improper positioning significantly increases the color change compared to the optimal position regardless of the type of composite (p < 0.001). For multi-peak LED, the type of resin composite and the curing condition displayed a significant effect on ΔE (p < 0.001). For both LEDs, the Vickers hardness and bottom/top ratio of Vickers hardness were affected by the type of composite and the curing condition (p < 0.01). Conclusions: The bulk fill composite presented greater resistance to wear, higher color stability, and better microhardness than the incremental composite when subjected to improper curing. The multi-peak LED improves curing under improper conditions compared to single-peak LED. Prevention of errors when curing composites requires the attention of all personnel involved in the patient's care once the clinical relevance of the appropriate polymerization reflects on reliable long-term outcomes.

An Acoustic Study of Korean and English Voiceless Sibilant Fricatives

  • Sung, Eun-Kyung;Cho, Yun-Jeong
    • 말소리와 음성과학
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    • 제2권3호
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    • pp.37-46
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    • 2010
  • This study investigates acoustic characteristics of English and Korean voiceless sibilant fricatives as they appear before the three vowels, /i/, /$\alpha$/ and /u/. Three measurements - duration, center of gravity and major spectral peak - are employed to compare acoustic properties and vowel effect for each fricative sound. This study also investigates the question of whether Korean sibilant fricatives are acoustically similar to the English voiceless alveolar fricative /s/ or to the palato-alveolar /$\int$/. The results show that in the duration of frication noise, English /$\int$/ is the longest and Korean lax /s/ the shortest of the four sounds. It is also observed that English alveolar /s/ has the highest value, whereas Korean /s/ shows the lowest value in the frequency of center of gravity. In terms of major spectral peak, while English /s/ reveals the highest frequency, English /$\int$/ shows the lowest value. In addition, evidence indicates that there is a strong vowel effect in the fricative sounds of both languages, although the vowel effect patterns of the two languages are inconsistent. For instance, in the major spectral peak, both Korean lax /s/ and tense /$s^*$/ show significantly higher frequencies before the vowel /$\alpha$/ than before the other vowels, whereas both English /s/ and /$\int$/ exhibit significantly higher frequencies before the vowel /i/ than before the other vowels. These results indicate that Korean sibilant fricatives are acoustically distinct from both English /s/ and /$\int$/.

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Rb D1 전이선에서 원자결맞음에 의한 비선형 광자기 효과 (Nonlinear magneto-optic effect based on atomic coherence in Rb D1-line)

  • 문한섭;이원규;안문희;김중복
    • 한국광학회지
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    • 제16권1호
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    • pp.7-12
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    • 2005
  • 우리는 버퍼 가스가 포함된 Rb 원자 증기셀을 이용하여 $^{87}$ Rb원자 D$_1$전이선에서 원자결맞음에 의한 비선형 광자기 신호를 관측했다. 측정된 가장 좁은 비선형 광자기 신호의 선폭은 2$\pi$${\times}$464 Hz이고, 이 때 비선형 광자기 효과에 의한 미분형 신호의 peak-to-peak 변화에 해당하는 자기장의 변화는 약 1 mGauss로 측정되었다. 이러한 결과는 고감도 자기장 측정을 위한 광자계 연구에 응용될 수 있다.

Mg-13.5wt%Ni 합금 수소화합물의 수소방출에 대한 부피법에 의한 열분석 (Volumetric Thermal Analysis of Hydrogen Desorption from Mg-13.5wt%Ni Hydride)

  • 한정섭;박경덕
    • 한국수소및신에너지학회논문집
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    • 제26권4호
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    • pp.308-317
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    • 2015
  • To investigate the effect of microstructure on the formation of the desorption peak, the volumetric thermal analysis technique (VTA) was applied to the Mg-13.5 wt% Ni hydride system. The sample made by the HCS (hydriding combustion synthesis) process had two kinds of Mg microstructures. Linear heating was started with various constant heating rates. Only one peak was appeared in the case of the small initial hydrogen wt% (0.83 wt%). Yet, two peaks were appeared with increasing initial hydrogen wt% (1.85 and 3.73 wt%) when only Mg was hydrogenated. The first peak was formed through the evolution of hydrogen from $MgH_2$, made by eutectic Mg. The second peak was formed through the evolution of hydrogen from $MgH_2$, made by primary Mg. Therefore, this result shows that the microstructure also has a considerable effect on forming the desorption peak. We have also derived the hydrogen desorption equations by VTA to get apparent activation energy when the rate-controlling step for the desorption of the hydrided system is the diffusion of hydrogen through the ${\alpha}$ phase and the chemical reaction ${\beta}{\rightarrow}{\alpha}$.

가다랑어 훈연조미제품 유래 저분자물질의 생리활성 (Biological Activities of Low Molecular Weight Substances Fractionated from the Seasoned and Smoked Products of Skipjack Tuna (Euthynus pelamis))

  • 이정민;최근표;원무호;김상무
    • 한국수산과학회지
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    • 제38권4호
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    • pp.219-225
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    • 2005
  • We studied the anticancer, antioxidative, ACE inhibitory, antithrombic, and cerebral ischemia inhibitory activities, of low molecular weight substances fractionated from the seasoned and smoked products of skipjack tuna (Euthynus pelamis). Low molecular weight substances fractionated from the liquid extract of seasoned and smoked skipjack tuna powder showed 7 peaks on gel permeation chromatography. Anticancer activity was the highest at Peak 3 $(54.23%)$ followed by Peak 4 $(41.58\%)$. The potency order of antioxidative activity was the highest at Peak 3 $(94.14\%)$ followed by Peak 2 $(82.07\%)$ and Peak 5 $(81.24\%)$. ACE inhibitory activity was the highest at Peak 3 $(67.27\%)$ followed by Peak 5 $(45.62\%)$. But there was weak anti thrombotic effect (PT and APTT) in the low molecular weight substances of the seasoned and smoked products of skipjack tuna. Cerebral ischemia inhibitory activity was the highest at Peak 3 $(80.0\%)$ followed by Peak 5 $(40.0\%)$.

권총의 최대반동력 측정 시스템 구축 (Establishment of The System for Checking Peak Recoil Force in a Pistol)

  • 박문선;엄혁;구태완;강범수
    • 한국정밀공학회지
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    • 제16권1호통권94호
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    • pp.87-94
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    • 1999
  • The peak recoil force in a pistol have an effect on the reliability of the frame and target shooting. The experimental system has been established for measurement of the peak recoil force, which consists of force and velocity sensors, high speed camera. For effective operation of the system, a software has also developed, and combined with the hardwares. Several pistols have been tested and compared quantitatively on the peak recoil force and impact energy. It is concluded that the established system can be utilzed for checking peak force, and data accumulation for new pistol design.

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댐 파괴형상에 따른 수문곡선 해석 (Analysis of Hydrograph by Dam Breach Shapes)

  • 박기범
    • 한국환경과학회지
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    • 제16권4호
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    • pp.487-493
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    • 2007
  • In this study is analysis which dams breach shapes are effect on peak discharge of dam-failure. The dam breach shapes and failure time are important peak discharge when dam failure. When dam failure times are 1hr, 2hr and 3hr condition for the ECRD and 0.1hr and 0.2hr for the CG and CFRD that breach shapes changed base length $B_b=1Hd,\;B_b=2Hd\;and\;B_b=3Hd$. As the results from DAMBRK(Dam Break model) peak discharge are increase base widths lengthen. As failure time is longer then peak discharge is decrease. So peak discharge is increase more short of dam failure time. Also peak discharge is increase become larger dam breach shapes.

정상인에서 보행 속도가 발바닥의 최대압력분포에 미치는 영향 (Effects of walking speed on peak plantar pressure in healthy subjects)

  • 하미숙;남건우
    • 대한물리치료과학회지
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    • 제22권2호
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    • pp.43-47
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    • 2015
  • Background : Many factors affect foot and ankle biomechanics during walking, including gait speed and anthropometric characteristics. This study examined the effect of walking speed on peak plantar pressure during the walking. Method : Thirty two normal healthy subjects (16 men, 16 women) were recruited. Peak plantar pressure was investigated using pressure distribution platforms (Pedoscan system) under the hallux heads of the first, second, and third metatarsal bones, and heel. Result : The results also suggest that slow walking speeds may decrease forefoot peak plantar pressure in patients with peripheral neuropathy who have a high risk of skin breakdown under the forefoot(p<0.05). Conclusion : The results also suggest that slow walking speeds may decrease forefoot peak plantar pressure in patients with restricted low extremity range of motion who have a high risk of skin breakdown under the forefoot.

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An experimental study of scale effect on the shear behavior of rock joints

  • Lee Tae-Jin;Lee Sang-Geun;Lee Chung-In;Hwang Dae-Jin
    • 한국지구물리탐사학회:학술대회논문집
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    • 한국지구물리탐사학회 2003년도 Proceedings of the international symposium on the fusion technology
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    • pp.156-161
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    • 2003
  • Mechanical behavior of rock joints usually can be characterized by small-scale laboratory shear tests due to economical and technical limitations, but their applicability to the behaviour of rock mass has been always questioned by a number of researchers because of scale effect. Though there have been several researches regarding the scale effect, it has been a controversial problem how to apply the result of small-scale laboratory shear test directly to field design from different conclusions among researchers. In order to grasp the trend of scale effect of shear behavior, a series of direct shear tests on replicas of natural rock joint surfaces made of gypsum cement with different size and roughness were conducted and analyzed. Result showed that as the size of the specimen increased, average peak shear displacement increased, but average shear stiffness and average peak dilation angle decreased. As for the dependency of scale on shear strength, the degree of scale effect was dependent on normal stress and roughness of rock joint. For the condition of low normal stress and high roughness, decrease of average peak shear strength with increasing size of joint was evident.

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