• Title/Summary/Keyword: pdm

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Hepatoprotective activity of terpenoids and terpenoid fractions of Scoparia dulcis L

  • Krishnamurthy, Praveen Thaggikuppe;Bajaj, Jitendra;Sharma, Abhishek;Manimaran, Sellappan;Ravanappa, Prashantha Kumar Bommenahalli;Pottekad, Vijayan
    • Advances in Traditional Medicine
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    • v.10 no.4
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    • pp.263-270
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    • 2010
  • Scoparia dulcis L. is widely used in the traditional system of medicine for treating liver ailments. In the present study the terpenoids and terpenoid fractions isolated from 1:1:1 petroleum ether, diethyl ether and methanol (PDM) extract of Scoparia dulcis L. were tested for their in vitro 1, 1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity. Selected samples from the assay were further tested for their in vitro hepatoprotective activity against $CCl_4$ induced hepatotoxicity in freshly isolated rat hepatocytes. In the in vitro antioxidant study, fractions 7, 11, 13, 14, and 15 and PDM extract show the DPPH radical scavenging activity. The phytochemical screening of all these fractions show the presence of terpenoids. In the in vitro hepatoprotective study all these fractions and the PDM extract significantly prevent the $CCl_4$ induced changes in the aspartate aspartate amino transferase, alanine amino transferase and alkaline phosphatase levels (p < 0.05). The above results are comparable with the standard, silymarin. The results of the study indicate that, the PDM extract of Scoparia dulcis L. possesses potential hepatoprotective activity and this may be attributed to its free radical scavenging potential, which in turn may be attributed to the presence of terpenoids.

Hydrophobic and Hydrophilic PDMS Sponges Prepared Through Physicochemical Treatments (물리화학적 처리에 따른 PDMS 특성 조절)

  • Nam, Kyungmok;Park, Sungmin;Kim, Jonghun;Yoon, Sang-Hee
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.40 no.8
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    • pp.737-742
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    • 2016
  • An elastomer (especially PDMS) sponge is considered to be a promising selective absorber in cleaning up oil spills. The performance of a PDMS sponge in capturing and separating oil from (sea) water depends on several parameters such as surface roughness, physicochemical treatments, and hydrostatic stability. Here, we first present a method of fabricating the PDMS sponges having numerous micro-sized pores that act as absorption and storage spaces for the target material, and then we report an experimental effort undertaken to control the surface physicochemistry (i.e., hydrophobicity or hydrophilicity) of the PDMS sponges by adjusting the size of the pores and the concentration of the surfactant (i.e., silwet L-77). From the experimental results, we develop an in-depth understanding of the mechanism for controlling the surface physicochemistry of PDMS using water-soluble micro-sized particles and a surfactant. The surface energy and absorbing behavior of the PDMS sponges are also extensively discussed.

Utilization-Focused Reduction of Radiation Exposure with XCP-DS FIT Sensor Holder by Measuring Dose of Dental X-ray Generator (구내 방사선발생기의 선량 분포측정을 통한 필름유지기구(XCP-DS FIT)의 피폭선량감소에 대한 유용성)

  • Lee, Kyung Hee
    • Journal of the Korean Society of Radiology
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    • v.6 no.6
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    • pp.465-471
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    • 2012
  • In this study, three dimensional X-ray dose distribution from dental X-ray generator system was measured by ALOKA PDM-117 dosimeter. The X-ray dose distribution will be change with XCP-DS FIT in oral shot, because the distance between X-ray generator and the dosimeter. The X-ray dose change affects on patient exposure and radiograph image quality. Therefore, it is important to obtain relation between the X-ray dose and the distance. The X-ray dose at the central position was decreased with increasing the distance. Furthermore, the dose at the edge of the X-ray flux was increased with increasing the distance. The increased dose affects on the patient radiation exposure. The present results will provide for good dental radiograph image and reducing radiation over-exposure on patient.

Comparative Assessment of the Conceptual Rainfall Runoff model and HEC-HMS in the Jeungpyeong catchment (증평유역의 개념적 강우-유출모형과 HEC-HMS모형 비교 평가)

  • Park, Ki-Soon;Lee, Hyo-Sang;Lee, Moo-Kyeong
    • Proceedings of the Korea Water Resources Association Conference
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    • 2012.05a
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    • pp.977-977
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    • 2012
  • 하천의 유량 측정은 대부분 홍수 예보지역, 댐 상류지역, 대하천 및 유역내 주요지점을 위주로 수행되고 있으나, 중소하천과 소유역에 대한 관측자료는 전무한 실정이다. 그로 인해 중소하천과 소유역 등 미계측 유역에 대한 유량 산정에 어려움이 있다. 본 연구에서는 미계측 유역에 대한 적합한 유량 산정방법의 검토를 위해 미호천의 소유역인 증평유역을 대상으로 9개의 개념적 강우-유출모형(3개의 토양저류모형과 3개의 유역유출모형의 조합)을 적용하였으며, 이에 대한 적용성 검토를 위해 국내 홍수량산정에 많이 활용되고 있는 HEC-HMS 모형으로 비교평가를 실시하였다. 이를 위하여 총 6개의 단기 홍수사상을 Monte Carlo 분석(Nash Sutcliffe Efficiency, NSE*)의 목적함수를 통하여 모형 매개변수의 검정 및 검증을 수행하였다. 두 모형의 단기 유출 모의 결과 검정에서 HEC-HMS는 목적함수값 0.06~1.44(NE S*)의 모형성능을 보여주었으며, 개념적 강우-유출 모형은 0.00~0.66(NES*)의 모형성능을 나타내었다. 개념적 강우-유출 모형과 HEC-HMS모형의 매개변수 최적화를 통한 검증 결과 HEC-HMS는 0.25(NES*)의 목적함수 값을 나타내었고, 9개의 개념적 강우-유출모형은 0.14~0.83(NES*)의 목적함수 값을 나타내었다. 이 중 CWI-3PAR, CWI-2PMP, PDM-3PAR와 PDM-2PMP 모형이 0.16~0.26(NES*)으로 우수한 성능을 보이며, HEC-HMS 모형의 첨두유량 과소평가에 대한 문제점을 해결하였다. 이를 통하여 CWI-3PAR, CWI-2PMP, PDM-3PAR와 PDM-2PMP 모형이 증평유역의 지역화를 위한 단기사상 강우유출모형으로 적합하다고 판단된다. 향후 연구유역을 확장하여 추가적인 연구를 통해 일반화된 결론을 얻을 필요가 있다.

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A Study on regionalization of PDM model parameters (확률분포모형(PDM)의 매개변수 지역화에 관한 연구)

  • Chang, Hyung Joon;Lee, Hyo Sang;Kim, Seong Goo;Park, Ki Soon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2017.05a
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    • pp.224-224
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    • 2017
  • 지구온난화로 인한 기후변화 등으로 안전한 하천구조물을 설계하기 위해서는 신뢰할 수 있는 홍수량 산정이 필요하다. 신뢰할 수 있는 홍수량 산정을 위해서는 정도 높은 과거 수문자료가 필요하나 국내의 많은 중소 규모유역이 미계측 유역 또는 과거 수문자료 부족으로 신뢰 할 수 있는 홍수량 산정이 어려운 실정이다. 본 연구에서는 미계측 유역의 홍수량 산정을 위하여 확률분포모형(PDM)의 매개변수 지역화를 수행하였다. 매개변수 지역화 연구를 수행하기 위하여, 금강 25개 유역을 대상으로 유역별 9~18개의 단기홍수수문사상을 선정하였다. 선정된 단기홍수수문사상을 확률분포모형에 적용하기위하여, MCAT (Monte Carlo Analysis Toolbox)을 활용하여 검정 및 검증을 수행하였으며, 목적함수는 수문곡선 모든 구간을 반영하는 NSE (Nash Sutcliffe Efficiency)와 고유량 부분을 반영하는 RMSE (Root Mean Squared Error) - FH를 적용하였다. 각각의 목적함수에 대하여 검정 모형 매개변수와 유역 특성인자의 다중 선형회귀식을 강우유출모형 매개변수 지역화 모형으로 제시하였다. 매개변수 지역화 결과의 평가를 위하여 청주 유역을 미계측 유역으로 가정하였다. 청주 유역에 대하여 지역화 매개변수를 적용한 결과, 17개의 사상 중 11개의 사상에서 NSE 목적함수 값이 0.5이상으로 전체적인 수문곡선의 경향성을 보였으며, 첨두 홍수량은 17개 사상 중 11개 사상에서 관측 첨두 홍수량 값의 20%이내를 제시하여 적합한 결과를 제시하였다. 또한 금강 25개 유역에 Jackknife 방법으로 검정 결과 관측 첨두 홍수량 값 20%이내의 성능을 보이는 사상이 56%를 포함하고 있어 의미있는 지역화 모형을 제시하였다고 판단된다. 본 연구에서 제시한 매개변수 지역화 방법은 미계측 유역의 유출모의에 활용될 수 있음을 확인하였다.

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The Driving Situation Judgment System(DSJS) using road roughness and vehicle passenger conditions (도로 거칠기와 차량의 승객 상태를 활용한 DSJS(Driving Situation Judgment System) 설계)

  • Son, Su-Rak;Jeong, Yi-Na;Ahn, Heui-Hak
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.14 no.3
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    • pp.223-230
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    • 2021
  • Currently, self-driving vehicles are on the verge of commercialization after testing. However, even though autonomous vehicles have not been fully commercialized, 81 accidents have occurred, and the driving method of vehicles to avoid accidents relies heavily on LiDAR. In order for the currently commercialized 3-level autonomous vehicle to develop into a 4-level autonomous vehicle, more information must be collected than previously collected information. Therefore, this paper proposes a Driving Situation Judgment System (DSJS) that accurately calculates the crisis situation the vehicle is in by useing the roughness of the road and the state of the passengers of surrounding vehicles including road information and weather information collected from existing autonomous vehicles. As a result of DSJS's PDM experiment, PDM was able to classify passengers 15.52% more accurately on average than the existing vehicle's passenger recognition system. This study can be a basic research to achieve the 4th level autonomous vehicle by collecting more various types than the data collected by the existing 3rd level autonomous vehicle.

산화아연 나노막대/PDMS 제작기술과 광학적 특성 연구

  • Go, Yeong-Hwan;Lee, Su-Hyeon;Yu, Jae-Su
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.474-474
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    • 2013
  • PDMS는 미세패턴을 위해 소프트 리소그래피 널리 활용되어질 뿐만 아니라, 재질이 투명하고 탄성과 강한 내구성을 갖고 있어 유연한 광학 및 전자소자에 이용될 수 있다. 최근에는, 이러한 PDMS를 서브파장구조(subwavelength grating structure)를 형성하거나 텍스쳐(texture)표면구조를 이용한 효과적인 반사방지막(antireflection coating)기판을 제작하여 태양전지 및 디스플레이 소자의 성능을 발전시키는 연구가 활발히 진행되고 있다. 한편, 수열합성법(hydrothermal method)이나 전기화학증착법(electrodeposition method)으로 비교적 간단한 공정을 통해서 다양한 기판위에 산화아연(ZnO) 나노막대(nanorod)를 수직정렬로 성장시킬 수 있는데, 이러한 구조는 반사방지특성의 유효 굴절률 분포(effective refractive index profile)를 갖고 있기 때문에 LED나 태양전지에 성능을 개선할 수 있다. 이에 본 연구에서는 수열합성법을 통해 성장된 수직 정렬된 산화아연 나노막대를 이용한 PDMS 표면의 미세패턴 형성하여 광학적 특성을 분석하였다. 실험을 위해, 스퍼터링을 통해서 산화아연 시드층을 형성한 후, 질산아연헥사수화물과 헥사메틸렌테트라민을 수용액에 담가두어 산화아연 나노막대를 성장시켰으며, PDMS의 베이스와 경화제의 질량비를 10:1으로 용액을 준비하여 수직 정렬된 산화아연 나노막대 표면을 casting method으로 코팅하여 열경화 처리하였다. 제작된 샘플의 형태, 구조 광특성을 관찰하기 위해서 전계방출형전자현미경, X선 회절 분석기, 분광 광도계를 이용하였다.

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Synthesis and Properties of Amphiphilic Polymers Containing Silicone (실리콘을 함유한 양친성 중합체의 합성 및 성질)

  • Yoon, Koo Sik;Sung, Yong Kiel;Kim, Sung Wan
    • Journal of the Korean Chemical Society
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    • v.39 no.1
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    • pp.76-80
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    • 1995
  • Polydimethylsiloxane(PDMS)-co-poly(2-hydroxyethyl methacrylate)(PHEMA) was prepared and the degree of swelling of solvents into the polymers was examined. It was confirmed that the solubility parameter of PHEMA homopolymer is 26 (J/cm3)1/2. Ethanol was significantly absorbed into copolymers containing large amount of PHEMA, while tetrahydrofuran was effectively absorbed into copolymers containing large amount of PDMS. Absorption of polar solvents into the copolymers were increased with the increase of PDMS content. The model drug, crystal violet (CV), was more absorbable into PDMS-HPEMA copolymers than PHEMA homopolymer. Absorption of CV was decreased with the increase of PDMS content of the copolymers.

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Advanced Induction Heating Equipment using Dual Mode PWM-PDM Controlled Series Load Resonant Tank High Frequency Inverters

  • Fathy, Khairy;Kwon, Soon-Kurl;Nakaoka, Mutsuo
    • Journal of Power Electronics
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    • v.7 no.3
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    • pp.246-256
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    • 2007
  • In this paper, a novel type auxiliary active edge resonant snubber assisted zero current soft switching pulse modulation Single-Ended Push Pull (SEPP) series load resonant inverter using IGBT power modules is proposed for cost effective consumer high-frequency induction heating (IH) appliances. Its operating principle in steady state is described by using each switching mode's equivalent operating circuits. The new multi resonant high-frequency inverter with series load resonance and edge resonance can regulate its high frequency output power under a condition of a constant frequency zero current soft switching (ZCS) commutation principle on the basis of the asymmetrical pulse width modulation (PWM) control scheme. Brand-new consumer IH products using the proposed ZCS-PWM series load resonant SEPP high-frequency inverter using IGBTs is evaluated and discussed as compared with conventional high-frequency inverters on the basis of experimental results. In order to extend ZCS operation ranges under a low power setting PWM as well as to improve efficiency, the high frequency pulse density modulation (PDM) strategy is demonstrated for high frequency multi-resonant inverters. Its practical effectiveness is substantially proved from an application point of view.

Phase Locked Loop based Pulse Density Modulation Scheme for the Power Control of Induction Heating Applications

  • Nagarajan, Booma;Sathi, Rama Reddy
    • Journal of Power Electronics
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    • v.15 no.1
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    • pp.65-77
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    • 2015
  • Resonant converters are well suited for induction heating (IH) applications due to their advantages such as efficiency and power density. The control systems of these appliances should provide smooth and wide power control with fewer losses. In this paper, a simple phase locked loop (PLL) based variable duty cycle (VDC) pulse density modulation (PDM) power control scheme for use in class-D inverters for IH loads is proposed. This VDC PDM control method provides a wide power control range. This control scheme also achieves stable and efficient Zero-Voltage-Switching (ZVS) operation over a wide load range. Analysis and modeling of an IH load is done to perform a time domain simulation. The design and output power analysis of a class-D inverter are done for both the conventional pulse width modulation (PWM) and the proposed PLL based VDC PDM methods. The control principles of the proposed method are described in detail. The validity of the proposed control scheme is verified through MATLAB simulations. The PLL loop maintains operation closer to the resonant frequency irrespective of variations in the load parameters. The proposed control scheme provides a linear output power variation to simplify the control logic. A prototype of the class-D inverter system is implemented to validate the simulation results.