• Proceedings of the KSMRM Conference
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• 1997.10a
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• pp.30-30
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• 1997

• Review of Korea Contents Association
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• v.6 no.4
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• pp.15-23
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• 2008

• Korean Journal of Biological Psychiatry
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• v.10 no.2
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• pp.126-132
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• 2003

Objectives:The purpose of this study is to examine the effects of venlafaxine, one of novel antidepressant drugs, on neurite growth in PC12 cells. Methods:PC12 cells were cultured with NGF for eight days. Then different concentrations($0{\mu}M$, $1{\mu}M$, $5{\mu}M$) of venlafaxine were mixed with cultured PC12 cells. After 24 hours and 48 hours of culture, we compared the effects of venlafaxine on the total length of neurites of cultured PC12 cells between no venlafaxine treated group($0{\mu}M$) and venlafaxine treated groups($1{\mu}M$ and $5{\mu}M$). Additionally, we studied the concentration-dependent effect of venlafaxine on differentiation in PC12 cells. Results:Experimental results showed that 1) the mean length of neurites in $1{\mu}M$ and $5{\mu}M$ venlafaxine treated group was more increased than no venlafaxine treated group(p=0.002). 2) the length of neurite in $5{\mu}M$ venlafaxine treated group was more elongated than $1{\mu}M$ venlafaxine treated group(p=0.046). 3) the length of neurite in $6{\mu}M$ venlafaxine treated group was more elongated than all the other concentrations in our experiment. Above $6{\mu}M$, the length of neurite was shortened in inverse proportion to the concentration of venlafaxine. Conclusions:This results suggest that venlafaxine, one of novel antidepressant drugs, promotes the differentiation of neuron. This study is believed to be a first step toward understanding the molecular and cellular mechanisms of antidepressant treatment.

• Journal of Korean Neurosurgical Society
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• v.29 no.9
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• pp.1188-1194
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• 2000

Objective : Internal carotid-posterior communicating artery(IC-PC) aneurysms can be clipped easily without any special preparations. Occasionally, however, it is difficult to clip the low-lying IC-PC aneurysms without some kinds of additional procedures. Clinical Material and Methods : We experienced four cases of low-lying IC-PC aneurysms, which the intradural anterior clinoidectomy and/or anterior petroclinoid fold(APF) resection was essential to expose the proximal side of the aneurysmal neck and/or proximal control. One patient harbored two low-lying IC-PC aneurysms bilaterally. The patients were divided into two groups according to the necessity of anterior clinoidectomy : Group I(n=4) that needed an intradural clinoidectomy and/or APF resection and Group II(n=29) that had IC-PC aneurysms, easily clipped without any special preparation. Also, various radiometric parameters were measured through the preoperative angiograms. Results : The incidence of such aneurysms was 12% among a total of thirty-three surgically treated IC-PC aneurysms during lasr 3 years. Among four cases, three cases presented with subarachnoid hemorrhage and all aneurysmal sac projected to postero-inferior direction. In our study, We initially considered the necessity of intraoperative anterior clinoid process(ACP) removal and/or resection of APF in cases of shorter distance less than 5.6mm between the proximal aneurysmal sac and tip of the ACP(p<0.001), and the proximal portion of aneurysmal neck has located below the interclinoid line(p=0.001). Conclusion : Through a careful preoperative evaluation, some radiometric parameters can be used to determine whether the ACP should be removed in clipping of the low-lying IC-PC aneurysms. Unlike to total removal of the ACP, the intradural partial anterior clinolidectomy and/or APF resection, which are more familiar to surgeons, reduce the risks of the premature rupture, operative time, and also contribute a more precise clip placement with proximal control than the extradural clinoidectomy.

• Journal of the Korea institute for structural maintenance and inspection
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• v.26 no.6
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• pp.14-22
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• 2022

In this study, a fire test was conducted to evaluate the fire performance of precast concrete (PC) slabs in an outdoor environment in response to the increase in fire incidents caused by the growth of warehouses. Prior to the field fire test, the tensile yield strength of the tendon at elevated temperatures was tested to analyze the mechanical properties. Also, by referring to previous studies, the thermal properties of tendon and the mechanical and thermal properties of concrete were investigated. A field fire test was conducted to analyze the structural and fire performance of two identical slabs with 50 and 150 mm bearing length. As the bearing length increased, deflection and horizontal displacement decreased. The fire test lasted for 200 minutes without the collapse of slabs, validating current codes. Based on the structural performance which maintained even with concrete spalling and rupture of some tendons, the bonded method is assumed to be practical in pre-tensioned PC slabs. The results of fire test are expected to be utilized in evaluating the fire performance of PC slabs in warehouses.

• Polymer(Korea)
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• v.29 no.6
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• pp.588-592
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• 2005

For the purpose of obtaining polycarbonate film which blocks ultra-violet ion beam was irradiated onto the surface of PC film. This method has gotten several advantages compared with the techniques, such as the protection of changes in film thickness and UV blocking material deposited onto a base film. In order to investigate UV blocking PC film, the optical and chemical characteristics, surface morphology and lightfastness were confirmed by UV/Vis, FTIR(ATR) spectroscopy, AFM, and Q-UV fasoess analyses. As a result, it was shown that the modified PC film was able to block almost all of UV region and easily control the degree of UV block. The optical changes in the film were attributed to chemical changes in PC surface by ion beam irradiation. Moreover, we expect that the modified PC film can durably block UV due to no changes in colour and UV transmittance after UV fastness test.

• 한국HCI학회:학술대회논문집
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• 2008.02a
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• pp.553-558
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• 2008

In this paper, we develop a vibration system which can generate diverse vibration effects in realtime by analyzing signals from the sound output of PC. This system is able to detect the occurrences of particular sounds in order to generate corresponding pre-programmed vibration patterns. It contributes to the improvement of the reality and the immersiveness of games and virtual reality applications. In addition, its advantage is to easily add vibration features to applications which were originally developed without consideration for vibration. Our system consists of an external DSP board for signal processing and a vibration pad which can be put on wrists. It is superior to other sound-driven vibration devices because its DSP board can detect more diverse sounds, has higher performance and does not interfere with PC. Also the wrist-wearable vibration pad is able to generate more realistic vibration than other mouse or joystick type devices.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.54 no.8
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• pp.375-387
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• 2005

This paper presents an application of parallel Genetic Algorithm-Tabu Search (GA-TS) algorithm to search an optimal solution of a service restoration in distribution systems. The main objective of service restoration of distribution systems is, when a fault or overload occurs, to restore as much load as possible by transferring the do-energized load in the out of service area via network reconfiguration to the appropriate adjacent feeders at minimum operational cost without violating operating constraints, which is a combinatorial optimization problem. This problem has many constraints with many local minima to solve the optimal switch position. This paper develops parallel GA-TS algorithm for service restoration of distribution systems. In parallel GA-TS, GA operators are executed for each processor. To prevent solutions of low fitness from appearing in the next generation, strings below the average fitness are saved in the tabu list. If best fitness of the GA is not changed for several generations, TS operators are executed for the upper $10\%$ of the population to enhance the local searching capabilities. With migration operation, best string of each node is transferred to the neighboring node after predetermined iterations are executed. For parallel computing, we developed a PC cluster system consists of 8 PCs. Each PC employs the 2 GHz Pentium IV CPU and is connected with others through ethernet switch based fast ethernet. To show the validity of the proposed method, proposed algorithm has been tested with a practical distribution system in Korea. From the simulation results, we can find that the proposed algorithm is efficient for the distribution system service restoration in terms of the solution quality, speedup, efficiency and computation time.

• Journal of Soil and Groundwater Environment
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• v.21 no.6
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• pp.135-145
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• 2016

MgO recently has been regarded as the alternative material for replacement of cement. The aim of this study is to investigate the effects of accelerated carbonation on the strength development of MgO-based binder which is binary mixtures of magnesium oxide (MgO) with portland cement (PC) or ground granulated blast furnace slag (GGBS) or fly ash (FA). The compressive strengths of all binders were higher in the 20% $CO_2$ condition and for longer curing time. The strength were generally higher as the following order: MgO/PC > MgO/GGBS > MgO/FA system. The binder composed of 20% MgO and 80% PC showed highest compressive strength (38.0MPa) which was higher than PC. The correlation analysis of the porosity and compressive strength showed that compressive strength was higher when porosity was lower. The hydration and carbonation products of MgO including brucite ($Ca(OH)_2$), magnesite ($MgCO_3$) and nesquehonite ($MgCO_3{\cdot}3H_2O$) presumably filled the pores and contributed to strength development. Thermogravimetric analyses elucidated that 0.34 kg of $CO_2$ could be stored the 50% MgO/50% PC binder which performed the maximum $CO_2$ uptake at 20% $CO_2$ condition.

• Journal of Microbiology and Biotechnology
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• v.15 no.4
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• pp.873-879
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• 2005

Red sea bream iridovirus (RSIV) obtained from infected rock bream was propagated by Bluegill fry-2 (BF-2) cell culture. The virus titer was determined as $10^{5.5}\;TCID_{50}/ml$ on confluent BF-2 cell monolayers. The integrin binding site of ORF 055L of infectious spleen and kidney necrosis virus (ISKNV) was selected for the construction of a primer to obtain the RSIV ORF 055L gene. The genes were amplified using RSIV gene lyzate by PCR. The homologies of the ORF 055L sequence of RSIV with ISKNV and rock bream iridovirus (RBIV) were approximately $96\%$ and $100\%$, respectively. DNA vaccine was constructed by cloning the ORF 055L of RSN into pcDNA 3.1 (+), containing a cytomegalovirus (CMV) promoter. For antibody production, pcDNA-055 DNA vaccine was injected to BALB/c mice. The production of antibodies against pcDNA-055 DNA vaccine was confirmed by the Western blot analysis. The antibodies produced by the pcDNA-055 DNA vaccine showed efficacy to neutralize the RSIV in the neutralization test in BF-2 cell culture.