• Animal cells and systems
• /
• v.5 no.3
• /
• pp.231-236
• /
• 2001

SINE-R retroposons have been derived from human endogenous retrovirus HERV-K family and found to be hominoid specific. Both SINE-R retroposons and HERV-K family are potentially capable of affecting the expression of closely located genes. From cDNA library of human fetal brain, we identified seven SINE-R retroposons and compared them with sequences derived from GenBank database. The SINE-R retroposons from human feta1 brain showed 85∼97% sequence similarities with the human-specific retroposon SINE-R.C2. They also showed 88∼96% sequence similarities with the sequence of the schizo-cDNA clone that derived from postmortem frontal cortex tissue of a schizophrenic patient. Phylogenetic analysis using the neiqhbor-joining method revealed that the seven new SINE-R retroposons from cDNA library of the human feta1 brain have proliferated independently during human evolution. The data indicate that such SINE-R retroposons are expressed in human fetal brain and deserve further investigation as potential leads to understanding of neuropsychiatric diseases.

• The Journal of Korean Academic Society of Nursing Education
• /
• v.19 no.3
• /
• pp.307-319
• /
• 2013

Purpose: The purpose of this study was to review nursing studies with regard to simulation- based learning in Korea. Methods: This systematic review examines the literature on simulation in nursing education from 2003 to 2012. The electronic databases reviewed included: RISS, the National Assembly Library, the National Library of Korea, and major nursing journal databases in Korea. The MeSH search terms included nursing, simulation, simulator, and standardized patient. Results: In total, 52 studies were included in the literature review. We included 21 quasi-experimental studies and 25 studies using high-fidelity simulation. They included knowledge and problem-solving ability in the cognitive domain; self efficacy, learning satisfaction, interpersonal relationships and communication, and confidence in the affective domain; and clinical performance ability and learning performance evaluation in the psychomotor domain. This systematic literature review revealed that simulation is useful in nursing education but uncovered a gap in the literature pertaining to the transfer of knowledge to performance and how to learn from cognitive reflection. Conclusions: This result suggests that it is necessary to conduct additional research on the cognitive learning process and transition to performance.

• Journal of the Korean Society for information Management
• /
• v.36 no.4
• /
• pp.21-52
• /
• 2019

This study focused on the domestic hospital libraries, the policies and support projects for them, and the current operation status of them. To this end, a list of hospital libraries was established and the operation status was investigated by conducting telephone interviews with 73 libraries collected. As a result, it was found that hospital libraries were established through support projects of other institutions (foundations, enterprises, etc.) rather than by the parent institutions, most of which were barely maintained except for certain actively operated ones. In terms of space, hospital libraries equipped with independent space were mostly operated on a small scale, and bookshelves were deployed in space for other purposes such as lounge and hallway. In terms of operation, a dedicated department or personnel for the library operation hardly existed, and more than half of them did not purchase additional books, simply maintaining the donated books at the time of the establishment. It was also shown that for services and programs, only booklending services are provided, except for a few libraries. Therefore, national policies and support will be needed to revitalize hospital libraries in the future, and the government needs to seek ways to continuously operate them through links with local representative libraries and public libraries.

• Journal of the Korean BIBLIA Society for library and Information Science
• /
• v.30 no.3
• /
• pp.195-221
• /
• 2019

The purpose of this study is to suggest implications from the case of health information service for patients in overseas hospital libraries. A total of 89 overseas hospital libraries were selected, including general hospitals, specialized hospitals, women's hospitals, children's hospitals, and veterans' hospitals. The health information service that is provided in general and common in 89 hospital libraries was surveyed and the differentiated health information service was investigated next. As a result, first, it can be seen that the establishment of hospital libraries and the provision of health information services are common outside of Korea. Second, various human resources such as librarians, health information specialists, medical specialists, social workers, clinical librarians, health education specialists, and volunteers are utilized. Third, it provides not only print materials but also various information sources such as electronic materials, websites, pamphlets, brochures, and provides health information in various languages. Fourth, in providing health (information literacy) education and programs, services are provided through linkage with hospitals, local public libraries, and local communities. The implications for domestic hospital libraries are as follows: First, the change of awareness of the establishment of hospital libraries and the provision of health information services; second, the support of the curriculum and associations and the need for continuing education; third, it is necessary to link with related organizations for mandatory and diversification of health information services in hospital libraries.

• Asian Oncology Nursing
• /
• v.12 no.4
• /
• pp.257-266
• /
• 2012

Purpose: The purpose of this study was to evaluate the effectiveness of patient education interventions on distress, self-care knowledge and self-care behavior in cancer patients. Methods: A total of 1,102 studies were retrieved from 6 electronic databases in Korea. From these studies, 18 studies met the inclusion criteria with a total of 850 participants. Two authors independently assessed the methodological quality by Cochrane's Risk of Bias and Methodological Items for Non Randomized Studies. The data were analyzed by the RevMan 5.1 program of Cochrane library. Results: Overall effect size of education interventions on anxiety was -2.12 (95% CI:-3.90, -0.34) (p<.001). The effects on self-care knowledge and self care behavior were -1.08 (95% CI:-1.73, -0.43) (p=.001), and -1.41 (95% CI:-2.13, -0.68) (p<.001), respectively. Publication bias was detected as evaluated by funnel plot, but the fail-safe number was moderate. Conclusion: This study suggests that patient education interventions can relieve anxiety and self-care. Further randomized controlled trials studies are needed to evaluate the effects of patient education intervention on depression.

• Journal of Dental Anesthesia and Pain Medicine
• /
• v.16 no.3
• /
• pp.165-173
• /
• 2016

Dentists often sedate patients in order to reduce their dental phobia and stress during dental treatment. Sedatives are administered through various routes such as oral, inhalation, and intravenous routes. Intravenous administration has the advantage of rapid onset of action, predictable duration of action, and easy titration. Typically, midazolam, propofol or dexmedetomidine are used as intravenous sedatives. Administration of these sedatives via infusion by using a syringe pump is more effective and successful than infusing them as a bolus. However, during intravenous infusion of sedatives or opioids using a syringe pump, fatal accidents may occur due to the clinician's carelessness. To prevent such risks, smart syringe pumps have been introduced clinically. They allow clinicians to perform effective sedation by using a computer to control the dose of the drug being infused. To ensure patient safety, various alarm features along with a drug library, which provides drug information and prevents excessive infusion by limiting the dose, have been added to smart pumps. In addition, programmed infusion systems and target-controlled infusion systems have also been developed to enable effective administration of sedatives. Patient-controlled infusion, which allows a patient to control his/her level of sedation through self-infusion, has also been developed. Safer and more successful sedation may be achieved by fully utilizing these new features of the smart pump.

• Journal of Preventive Medicine and Public Health
• /
• v.50 no.2
• /
• pp.68-82
• /
• 2017

Objectives: We performed a systematic review to assess and aggregate the available evidence on the frequency, expected effects, obstacles, and facilitators of disclosure of patient safety incidents (DPSI). Methods: We used the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines for this systematic review and searched PubMed, Scopus, and the Cochrane Library for English articles published between 1990 and 2014. Two authors independently conducted the title screening and abstract review. Ninety-nine articles were selected for full-text reviews. One author extracted the data and another verified them. Results: There was considerable variation in the reported frequency of DPSI among medical professionals. The main expected effects of DPSI were decreased intention of the general public to file medical lawsuits and punish medical professionals, increased credibility of medical professionals, increased intention of patients to revisit and recommend physicians or hospitals, higher ratings of quality of care, and alleviation of feelings of guilt among medical professionals. The obstacles to DPSI were fear of medical lawsuits and punishment, fear of a damaged professional reputation among colleagues and patients, diminished patient trust, the complexity of the situation, and the absence of a patient safety culture. However, the factors facilitating DPSI included the creation of a safe environment for reporting patient safety incidents, as well as guidelines and education for DPSI. Conclusions: The reported frequency of the experience of the general public with DPSI was somewhat lower than the reported frequency of DPSI among medical professionals. Although we identified various expected effects of DPSI, more empirical evidence from real cases is required.

• Korean Journal of Clinical Pharmacy
• /
• v.28 no.1
• /
• pp.30-39
• /
• 2018

Background: Clinical Pharmacy Practice Experience (CPPE) is an important curriculum that offers students patient-centered disease prevention and treatment with evidence-based optimal pharmacotherapy for better clinical outcomes. However, few studies have evaluated the perception of pharmacy students regarding CPPE in tertiary and secondary hospitals. This study aimed to evaluate the perception of pharmacy students regarding the learning program of CPPE. Methods: The survey questionnaire consisted of 15 self-administered questions regarding pharmacy practices, barriers, and improvement of practical training. Fourteen institutional pharmacies located in seven regions responded to a survey questionnaire from March 1 to June 30, 2017. The participants were pharmacy students doing clerkship in a hospital setting. Results: The response rate was 73.6%. Thirty-five participants (22.4%) had used a hospital library, but 121 (77.6%) had never used the library for drug information resources. Eighty-one (50.0%) responded that clinical knowledge and drug information was the most beneficial practice. Thirty-seven (31.1%) respondents in the tertiary hospitals and 19 (46.3%) in the secondary hospitals answered that they were filling prescriptions during the daily break. On the other hand, 72 respondents (60.5%) in the tertiary hospitals and 17 (41.5%) in the secondary hospitals did literature research to prepare for presentation. Conclusion: More students in secondary hospitals continue to fill prescriptions during the daily break, as compared to those in tertiary hospitals. Therefore, the authors suggest self-directed learning to improve clinical performance and each institution considers offering onsite or online library service to improve evidence-based CPPE for pharmacy school students.

• International Journal of Internet, Broadcasting and Communication
• /
• v.12 no.4
• /
• pp.188-195
• /
• 2020

Purpose: This study aimed to review the recent scientific literature regarding nursing care of arteriovenous fistula (AVF) for the patients with Chronic Renal Failure (CRF) undergoing hemodialysis. Methods: An integrative review was conducted and articles were searched from Cochrane library, Medline, PubMed, Science direct and CINAHL databases by using the terms "nursing", 'Chronic Renal Failure', 'Haemodialysis', renal failure', 'or 'AV Fistula' nursing care', 'self-care'. The inclusion criteria were articles published in English in the year of 2015-2020 with availability of free full text. Reviewed data were carefully analyzed and charted regard to the nursing care of the patient with AVF. Results: 12 articles papers met the inclusion criteria. Three themes were derived from the data: (a) Intervention (b). Patient and nurse education (c) KPA Assessment of (Knowledge, Practice and Attitude) Conclusions: This review indicates the challenges that nursing care of AVF patients undergoing hemodialysis. The identified themes can be used in the development of more effective educational- programs. Future studies should focus on the development and evaluation of educational programs that include these selected themes.

• Journal of Internet of Things and Convergence
• /
• v.2 no.4
• /
• pp.15-20
• /
• 2016

This paper describes the construction of knowledge data retrieval management system based on medical image CT. The developed system is aimed to improve the efficiency of the hospital by reading the medical images using the intelligent retrieval technology and diagnosing the patient 's disease name. In this study, the medical image DICOM file of PACS is read, the image is processed, and feature values are extracted and stored in the database. We have implemented a system that retrieves similarity by comparing new CT images required for medical treatment with the feature values of other CTs stored in the database. After converting 100 CT dicom provided for academic research into JPEG files, Code Book Library was constructed using SIFT, CS-LBP and K-Mean Clustering algorithms. Through the database optimization, the similarity of the new CT image to the existing data is searched and the result is confirmed, so that it can be utilized for the diagnosis and diagnosis of the patient.