• Archives of Plastic Surgery
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• 제49권2호
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• pp.227-239
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• 2022

Complications experienced during lymphatic surgery have not been ubiquitously reported, and little has been described regarding how to prevent them. We present a review of complications reported during the surgical management of lymphedema and our experience with technical considerations to reduce morbidity from lymphatic surgery. A comprehensive search across different databases was conducted through November 2020. Based on the complications identified, we discussed the best approach for reducing the incidence of complications during lymphatic surgery based on our experience. The most common complications reported following lymphovenous anastomosis were re-exploration of the anastomosis, venous reflux, and surgical site infection. The most common complications using groin vascularized lymph node transfer (VLNT), submental VLNT, lateral thoracic VLNT, and supraclavicular VLNT included delayed wound healing, seroma and hematoma formation, lymphatic fluid leakage, iatrogenic lymphedema, soft-tissue infection, venous congestion, marginal nerve pseudoparalysis, and partial flap loss. Regarding intra-abdominal lymph node flaps, incisional hernia, hematoma, lymphatic fluid leakage, and postoperative ileus were commonly reported. Following suction-assisted lipectomy, significant blood loss and transient paresthesia were frequently reported. The reported complications of excisional procedures included soft-tissue infections, seroma and hematoma formation, skin-graft loss, significant blood loss, and minor skin flap necrosis. Evidently, lymphedema continues to represent a challenging condition; however, thorough patient selection, compliance with physiotherapy, and an experienced surgeon with adequate understanding of the lymphatic system can help maximize the safety of lymphatic surgery.

• 한국임상약학회지
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• 제32권2호
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• pp.125-132
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• 2022

Background: Fixed-dose combinations have the advantage of improving patient compliance, but may increase the risk of duplicate prescriptions. As the use of fixed-dose combination antihypertensives increases, it is necessary to investigate the current status of class duplication prescriptions (CDP) in patients taking fixed-dose combination antihypertensives in Korea and to identify factors associated with CDP. Methods: We conducted a retrospective observational study using nationally representative claim data. Hypertensive patients aged 20 years or older taking fixed-dose combination antihypertensives were extracted. Among these patients, patients with CDP were identified. A chi-square test was applied to determine the differences between patients with CDP and non-CDP. The associated factors of CDP were identified through multiple logistic regression. Results: Of the 74,165 patients who were prescribed fixed-dose combination antihypertensives, 426 patients (0.6%) with CDP were identified. The most common antihypertensive class associated with CDP was calcium channel blockers (194 patients, 45.5%), followed by angiotensin II receptor blockers (136 patients, 31.9%). Patients aged 75 years or older (odds ratio [OR] 1.83, 95% confidence interval [CI] 1.02-3.52), chronic kidney disease (OR 4.45, 95% CI 2.15-8.25), chronic heart failure (OR 2.71, 95% CI 1.93-3.72), coronary artery disease (OR 2.22, 95% CI 1.60-3.03) and Medical Aid/Patriots and Veterans Insurance (OR 1.49, 95% CI 1.04-2.07) were significantly associated with increased CDP. Conclusions: The factors associated with CDP were the elderly, comorbidities, and low socioeconomic status. Since CDP can result in negative clinical outcomes, active intervention by the pharmacist is warranted.

• Clinical Pain
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• 제16권1호
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• pp.20-25
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• 2017

Objective: To find that the patients who conducted home self-exercise in conjunction with intra-articular corticosteroid injection will have better improvement in subacromial subdeltoid (SASD) bursitis symptoms than those who received only an injection. Method: A prospective, nonrandomized, comparison study was conducted in outpatient rehabilitation clinic in a tertiary university hospital. Patients diagnosed with SASD bursitis with physical examination and ultrasound evaluation were included and received ultrasound guided injection (UGI). Patients were divided into two groups according to the compliance of self-exercise: UGI-exercise group and UGI only group. Visual analog scale (VAS) was checked before, at 3 weeks, 3 months, and 6 months after the UGI. A patient's global impression of change (PGIC) survey was made at 3 months after the UGI. Results: A total of 82 patients with SASD bursitis were included. At 3 weeks after the injection, the mean VAS for the UGI-exercise group was 2.6 ± 1.7 and for UGI only group was 1.9 ± 1.3 (p=0.030). At 3 months after the injection, the mean VAS for the UGI-exercise group was 4.0 ± 1.3 and for UGI only group was 5.4 ± 1.4 (p<0.001). Conclusion: We concluded that home-based self-exercise of the shoulder provides an additional benefit for pain alleviation possibly with prolonging the effect of injection in SASD bursitis.

• 대한의용생체공학회:의공학회지
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• 제44권6호
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• pp.428-442
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• 2023

In this study, we have a goal to develop usability evaluation guidelines for heuristic-based artificial intelligence-based Software as a Medical Device (SaMD) in the medical field. We conducted a gap analysis between medical hardware (H/W) and non-medical software (S/W) based on ten heuristic principles. Through severity assessments, we identified 69 evaluation domains and 112 evaluation criteria aligned with the ten heuristic principles. Subsequently, we categorized each evaluation domain into five types, including user safety, data integrity, regulatory compliance, patient therapeutic effectiveness, and user convenience. We proposed usability evaluation guidelines that apply the newly derived heuristic-based Software as a Medical Device (SaMD) evaluation factors to the risk management process. In the discussion, we also have proposed the potential applications of the research findings and directions for future research. We have emphasized the importance of the judicious application of AI technology in the medical field and the evaluation of usability evaluation and offered valuable guidelines for various stakeholders, including medical device manufacturers, healthcare professionals, and regulatory authorities.

• 대한불안의학회지
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• 제19권2호
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• pp.37-47
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• 2023

This review article explores the psychological characteristics, comorbid mental disorders, and psychosocial assessments throughout the solid organ transplant journey, spanning the pre-transplant, peri-transplant, and post-transplant phases for transplant recipients. The psychological burden and anxiety in the pre-transplant phase are high for organ failure patients with complex physical difficulties who are deciding to undergo transplantation and are on the waiting list. The pre-transplant psychosocial evaluation covers various aspects, including the patient's readiness, awareness of, and commitment to transplant treatment, medical compliance, psychopathological conditions such as cognitive function and personality disorders, lifestyle factors, including substance abuse, as well as various psychosocial factors like social support. During the peri-transplant phase, mental health problems such as postoperative delirium should be carefully recognized and addressed. After transplantation, it is essential to assist patients in coping with the various stressful experiences they encounter, manage psychiatric symptoms such as depression, anxiety, and insomnia, and improve treatment adherence and quality of life during long-term care for the transplanted organ. Managing psychiatric problems in post-transplant patients requires a deep understanding of immunosuppressant medications and a keen awareness of associated risks, including adverse effects and potential drug interactions. This comprehensive review emphasizes the significance of proactive mental health care and psychosocial evaluation, highlighting the necessity of a multidisciplinary approach to enhance the quality of life and overall success of transplant patients throughout all phases of transplantation.

• 정신신체의학
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• 제28권1호
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• pp.53-62
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• 2020

연구목적 최근 공황장애와 초기 외상 사건에 대한 연구결과가 축적되는데, 아직까지 공황장애의 경과나 치료와 아동기 외상 연구는 드문 실정이다. 이 연구는 공황장애 외래 환자에서 아동기 외상 병력과 약물치료 유지 기간 사이의 상관 관계를 조사하였다. 방 법 이 횡단적 연구는 한 대학병원 정신건강의학과 외래를 방문한 공황장애 환자를 대상으로 일생의 외상력, 우울, 불안 및 외상후 스트레스 증상과 약물치료 기간을 조사하였다. 2012년 3월~2016년 2월까지 총 135명의 공황장애 외래 초진 환자를 대상으로 설문지 연구를 실행하였으며 이중 53명(39%)이 거절하거나 불완전한 설문을 작성하여 나머지 82명의 자료를 분석하였다. 설문지에는 외상력 선별 검사(Trauma History Screen), 벡우울척도, 벡불안척도, 간편 외상후 스트레스 장애 체크리스트 설문지가 포함되었다. 결 과 일생 동안 경험한 외상 종류의 수와 치료기간은 음의 상관관계를 나타내었다(rho=-0.269, p=0.015). 외상의 아형을 볼 때는 아동기 신체 학대와 치료 기간 사이에 유의한 부정 상관 결과를 보였다(rho=-0.298, p=0.007). 결 론 이 연구의 결과는 심리적 외상, 특히 아동기의 대인관계적 외상이 공황장애의 치료 유지에 영향을 줄 수 있는 것을 시사한다. 향후 연구에서는 아동기 외상과 불량한 치료 유지를 중재하는 요인, 예를 들어 치료 관계나 치료에 대한 기대 부족 등에 대한 연구가 필요하다.

• 한국산학기술학회논문지
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• 제18권3호
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• pp.258-269
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• 2017

본 연구는 Pender(1996)의 건강증진모형을 중심으로 유방암 환자의 건강증진행위 예측요인을 파악하기 위해 시도한 서술적 조사연구이다. 2015년 9월 18일부터 10월 26일까지 구조화된 설문지를 이용하여 유방암 환자 121명을 대상으로 자료를 수집하였다. 수집된 자료는 SPSS 20.0 for Windows 프로그램을 이용하여 t-test, ANOVA와 Scheffe 사후검정, Pearson correlation coefficients 및 위계적 다중회귀분석 방법으로 분석하였다. 대상자의 건강증진행위 예측요인은 사회적지지, 행동계획 몰입, 이전건강 행위, 행위관련 감정, 지각된 자기효능감, 가족기능, 지각된 유익성, 상황적 영향 등 8가지 변수로 파악되었고, 총 설명력은 58%이었다. 이상으로 유방암 환자들이 재활기에 최적의 건강을 유지하고 질 높은 삶을 살 수 있도록 돕기 위해서는 대상자의 건강증진행위 수준을 상승시키도록 돕는 간호중재의 개발과 적용이 필요하다. 특히 본 연구결과 유방암 환자의 건강증진행위 예측요인으로 밝혀진 사회적 지지, 행동계획 몰입, 이전건강 행위, 행위관련 감정, 지각된 자기효능감, 가족기능, 지각된 유익성 및 상황적 영향 수준이 낮은 대상자들에게 특별히 관심을 가질 필요가 있겠다.

• 대한소아치과학회지
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• 제34권4호
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• pp.685-693
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• 2007

골격성 부조화가 없는 I급 부정교합은 치아-악궁 간의 크기 차이에 의한 총생(crowding)이나 공극(spacing)이 주된 문제점이다. 이와 같은 경미한 공간 부조화를 개선시키고자 할 때, 치열의 종류, 치아-악궁크기 부조화의 양, 환자의 협조도, 또는 환자의 요구 등에 따라 치료 방법은 다양할 수 있다. 본 증례보고에서는 I급 구치부 관계를 지니면서 전치부의 치아-악궁크기 부조화의 양이 크지 않은 영구치열에서 상하악 전치부의 경미한 총생이나 공극이 관찰되는 경우에 사용할 수 있는 clear aligner와 spring aligner 장치의 이용에 관하여 보고하고자 한다. 이와 같은 장치들의 임상 적용에는 몇 가지 제한적인 조건이 있기는 하지만, 잘 선택된 증례에서는 매우 유용하며 편리하게 이용될 수 있다. 특히 총생이 존재하는 경우에는 이를 해소시킬 공간이 치열 내에서 확보되어야 하므로, 확실한 분석과 진단으로 치아 인접면 삭제의 양을 정확히 결정하여 각 치아들의 근심면과 원심면에서의 삭제의 양이 균등히 이루어질 수 있도록 하는 것이 바람직하다. 또한 치간에 공극이 존재하는 경우에는 배열 후 치열궁 둘레의 감소와 함께 상하악 전치부 간의 overjet 문제가 생길 수 있어 대합치열과의 교합관계에 신중을 기하여야 한다.

• 한국방사선학회논문지
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• 제9권7호
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• pp.445-448
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• 2015

최근 다색 X-ray 중 저에너지 광자의 비율을 감소시키는 필터에 대한 관심이 대두되고 있으나 X선 경화현상으로 인하여 나타나는 영상 화질에 영향에 대해서는 간과되고 있는 실정이다. 이에 본 연구에서는 필터에 따른 전방산란율의 변화를 평가함으로써 의료영상 품질에 영향을 미치는 산란선량을 정량적으로 고찰하였다. 실험 결과, 필터 두께가 증가함에 따라 최대 13.9%p의 전방산란율이 증가하는 추세가 나타나는 것으로 평가되었다. 이러한 결과를 바탕으로 한국 산업규격에서 권고된 필터 두께를 준수할 경우 환자의 피폭선량을 저감하면서도 약 1%p 이내의 전방산란율 만이 의료영상에 노이즈에 추가적으로 기여할 것으로 사료된다. 그러므로 환자의 피폭선량을 저감화하면서도 의료영상의 품질을 개선하기 위해서는 적절한 필터의 활용이 중요할 것으로 사료된다.

• Journal of Nutrition and Health
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• 제33권8호
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• pp.813-823
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• 2000

The purpose of this study was to investigate the effects of the nutrition therapy and drug(simvastatin) treatment on the levels of blood lipids for the hyperlipidemic patients according to genetic polymorphism of apo CIII. Subjects of the study consisted of 43(male: 9, female: 34 )hyperlipidemic patients registered to Kyung Hee Medical Center, Intakes of nutrients for the subjects were determined by 24-hr recall method through a personal interviews. The subjects were instructed to take the hypolipidemic and hypocholesterolemic diets. Compliance was monitored through food records, personal interview, and body-weight measurements. The patients changed their basal diet containing 40. 1g fat(182.7mg cholesterol./day) to a diet containing 30.7g fat(139.2mg cholesterol/day) after 12 weeks of nutrition therapy. The distribution of genotypes for apo CIII by Msp I was 32.5% of TT, 50.0% of TC, and 17.5% of CC. aT the beginning of the study, the level of blood triglyceride was the highest for patients with TT and TC. Following the nutrition therapy, patients with CC exhibited the largest drop of blood triglyceride. Following simvastatin treatment with nutrition therapy, blood LDL-cholesterol decreased in most of the patiens with TT. Meanwhile the distribution of genotypes for apo CII by the Fok I was 10.0% of TT, 47.5% of TC, and 42.5% of CC. The level of blood triglyceride was the highest for patients with CC. Following the nutrition therapy, patients with TC exhibited a significant drop for the blood triglyceride. Following simvastatin treatment with nutrition therapy the level of blood LDL-cholesterol decreased in most of the patients with CC. We concluded that dietary habits and food have been changed by nutrition therapy. And blood lipid levels have been decreased by the restriction of intakes of energy, fat and cholesterol. There was variation in the levels of blood lipids according to apo CII polymorphisms. The level of blood lipids responded to nutrition therapy and drug treatment in different was according to genetic polymorphisms. Accordingly, the choice of individualized therapy based on the patient\\`s genetic polymorphism is very important for effective therapy(Korean J Nutrition 33(8) : 813-823, 2000)