• YAKHAK HOEJI
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• v.47 no.2
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• pp.78-84
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• 2003

Local anesthetics are used to reduce pain, but they are so frequently injected to patients. So, we prepared lidocaine solid lipid microspheres (SLM) as long acting abdominal injection using spray drying method and evaluated drug entrapment, particle size, SEM, zeta potential and in vitro and in vivo drug release pattern, The particle sizes of SLM were 30∼100$\mu$m and it is enough to inject into abdominal tissue. The entrapment efficiency of SLM was over 95％ as spray drying method. Surfactant and PC decreased the burst effect by 20∼30％. In in vivo test, C-6 showed controlled release concentration profile in plasma for 8 days and C-5 sustained longer than we expected.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09a
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• pp.219-220
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• 2006

To understand the effect of powder characteristics on the thermal debinding behavior, PIM parts produced with powders with different particle sizes and particle shapes were examined to determine their weight losses during thermal debinding. The results show that the average diameter of the pore channel in the compact increased when the temperature increased and when coarse powders were used. However, the weight loss rates did not increase proportionally with the pore size. This suggests that the different powders that are frequently used in PIM parts do not affect the thermal debinding rate significantly. This is because the pore size is much larger than the mean free path of the decomposed gas molecules. Thus, the diffusion rates of the gases are not rate-controlling in thermal debinding. The controlling mechanism of the thermal debinding rate is the decomposition of the backbone binder in the PIM parts.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09a
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• pp.238-239
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• 2006

Nozzle geometry influences gas dynamics making sprayed particle behavior one of the most important parameters in cold spray process. Gas flows at the entrance convergent section of the nozzle takes place at relatively high temperature and are subsonic. Thus, this region is a very suitable environment for heating spray particle. In this study, numerical simulation and experiments were conducted to investigate the effect of nozzle contour, entrance geometry of nozzle and powder injection position at nozzle on the cold spray process. The process changes were observed through numerical simulation studies and the results were used to find a correlation with coating properties.

• Journal of Mechanical Science and Technology
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• v.16 no.8
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• pp.1135-1143
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• 2002

The intermittent spray characteristics of the single-hole diesel nozzle (d$\sub$n/=0.32 mm) used in the fuel injection system of heavy-duty diesel engines were experimentally investigated. The mean velocity and turbulent characteristics of the diesel spray injected intermittently into the still ambient were measured by using a 2-D PDPA (phase Doppler particle analyzer) . The gradient of spray half-width linearly increased with time from the start of injection, and it approximated to 0.04 at the end of the injection. The axial mean velocity of the fuel spray measured along the radial direction was similar to that of the free air jet within R/b= 1.0-1.5 regardless of elapsing time, and its non-dimensional distribution corresponds to the theoretical velocity distributions suggested by Hinze in the downstream of the spray flow fields. The turbulent intensity of the axial velocity components measured along the radial direction represented the 20-30% of the U$\sub$cι/ and tended to decrease in the outer region. The turbulent intensity in the trailing edge was higher than that in the leading edge.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2006.09a
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• pp.39-40
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• 2006

The relationship between the powder particle size change and a mechanical property of the Metal Injection Molding (MIM) product was examined in detail. The XRD results indicate that the diffraction peaks of BCC appeared in compacts of powder particle size of 4 to $10{\mu}m$ as well as the bulk SUS630. However, the diffraction peaks from both BCC and FCC were observed in the compact with powder size less than $3{\mu}m$. TEM observation revealed that the powder with those BCC/FCC two phase structure have a finely dispersed $SiO_2$ precipitates. Because the Si is ferrite stabilizing element, decrease of Si composition in the matrix phase by the $SiO_2$ precipitation resulted in formation of the retained austenite. Therefore, controlling the elements such as Si as well as oxygen decrease is very important to obtain a normal microstructure in ultra-fine powder $(<3{\mu}m)$ injection molding.

• The Bulletin of The Korean Astronomical Society
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• v.43 no.2
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• pp.42.1-42.1
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• 2018

Collisionless shocks with low sonic Mach numbers, M<4, are expected to accelerate cosmic ray (CR) protons via diffusive shock acceleration (DSA) in the intracluster medium (ICM). However, observational evidence for CR protons in the ICM has yet to be established. Performing particle-in-cell simulations, we study the injection of protons into DSA and the early development of a nonthermal particle population in weak shocks in high ${\beta}$ plasmas. Reflection of incident protons, self-excitation of plasma waves via CR-driven instabilities, and multiple cycles of shock drift acceleration are essential to the early acceleration of CR protons in supercritical quasi-parallel shocks. We find that only in ICM shocks with $M{\geq}2.3$, a sufficient fraction of incoming protons are reflected by the overshoot in the shock electric potential and magnetic mirror at locally perpendicular magnetic fields, leading to efficient excitation of magnetic waves via CR streaming instabilities and the injection into the DSA process. Since a significant fraction of ICM shocks have M < 2.3 CR proton acceleration in the ICM might be less efficient than previously expected. This may explain why the diffuse gamma-ray emission from galaxy clusters due to proton-proton collisions has not been detected so far.

• Journal of Korea Foundry Society
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• v.14 no.6
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• pp.530-540
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• 1994

Aluminium-silicon alloy(JIS AC8A) matrix composites reinforced with SiC particles were fabricated by spray-cast forming process, and the microstructure of powders and preforms produced were studied by using an optical and scanning electron microscopy. SiC particles were co-sprayed by mixed phase injection method during the spray casting process. Most of the composite powders formed by this mixed phase injection method exhibit morphology of particle-embedded type, and some exhibits the morphology of particle attached type due to additional attachment of the SiC particles on the surface of the powders in flight. The preforms deposited were resulted in dispersed type microstructure. The pre-solidified droplets and the deposited preform of SiC-reinforced aluminium alloy exhibit finer equiaxed grain size than that of unreinforced aluminium alloy. Eutectic silicons of granular type are crystallized at the corner of the aluminum grains in the preforms deposited, and some SiC particles seem to act as nucleation sites for primary/eutectic silicon during solidification. Such primary/eutectic silicons seem to retard grain growth during the continued spray casting process. It is envisaged from the microstructural observations for the deposited preform that the resultant distribution of SiC injected particles in the Al-Si microsturcture is affected by the amount of liquid phase in the top part of the preform and by the solidification rate of the preform deposited.

• Proceedings of the KSME Conference
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• 2000.11b
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• pp.174-179
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• 2000

Ultrafine particles have been used widely in many high technology industrial areas. The spherical nonagglomerated and uniform nanometer-size $SiO_2$ particles are synthesized by the direct injection of TEOS(Tetraethyorthosilicate) using electro-hydrodynamic spray ins method. Electro-hydrodynamic spray can generate in the range of submicron-size TEOS particles with high electric charge by applying a high electric field between the liquid injection nozzle and the reaction tube. This TEOS particles are thermally decomposed or oxidized to produce nanometresized $SiO_2$ particles in the reaction tube. Spherical, nonagglomerated and ultrafine particle generated and examined at furnaced temperature, $800^{\circ}C$ and TEOS flowrate of 0.49 or $1.00cm^3/hr$ using SEM and SMPS. As the total gas flowrate changes from 1.51pm to 5.01pm, the mean diameter of $SiO_2$ particle decreases from 120 nm to 68nm.

• Journal of ILASS-Korea
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• v.10 no.3
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• pp.1-8
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• 2005

The purpose of this study is to investigate the internal structure of the impinged diesel spray at various experimental conditions. To examine the effect of various factors on the development of a diesel spray impinging on the wall, experiments were conducted at the various Injection pressures, wall distances from the nozzle tip and angles of wall inclination. The PIV system consists of a double pulsed Nd:YAG laser was utilized to analyze the internal flow structure of impinged diesel sprays. The velocity fields from the PIV system were compared with the results measured by the phase Doppler particle analyzer(PDPA)system. The results show that internal flow pattern of the impinged spray was similar with the results from the PDPA system. The radial velocity of the impinged spray was increased with the increase in the injection pressure and near the nozzle-wall distance. The generation of vortex was also promoted with the Increase in angles of wall inclination.

• Transactions of the Korean Society of Automotive Engineers
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• v.13 no.1
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• pp.9-18
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• 2005

The objective of this study is to analyse the spray characteristics according to the injection duration under the ambient pressure condition, and the injection timing in the visualization engine. In order to investigate the spray behavior, we obtained the spray velocity using the PIV method that has been an useful optical diagnostics technology, and calculated the vorticity from spray velocity component. These results elucidated the relationship between vorticity and entropy which play an important role in the diffusion process for the early injection case and the stratification process for the late injection case. In addition, we quantified the homogeneous diffusion rate of spray using the entropy analysis based on the Boltzmann's statistical thermodynamics. Using these method, it was found that the concentration of spray droplets caused by the increase of injection duration is more effective than the increase of momentum dissipation. We also found that the homogeneous diffusion rate increased as the injection timing moved to the early intake stroke process and BTDC $50^{\circ}$ was the most efficient injection timing for the stratified mixture formation during the compression stroke.