• Title/Summary/Keyword: partial response

Search Result 927, Processing Time 0.033 seconds

The effect of Picibanil sclerotherapy for benign neck cysts (양성 경부 낭종에서의 Picibanil(OK-432)을 이용한 경화치료 효과)

  • Hong, Ji-Won;Boo, Sung-Hyun;Park, Jae-Hong;Kim, Myung-Gu
    • Korean Journal of Bronchoesophagology
    • /
    • v.14 no.2
    • /
    • pp.31-37
    • /
    • 2008
  • Background and Objectives: In most cases of benign neck cysts, surgical excision has been considered as treatment of choice. However, sometimes complete excision is very difficult, and recurrences has been occured due to insufficient surgery frequently. In this point of view, non-surgical treatment has been attempted with sclerosing agents such as picibanil(OK-432). In this study, we evaluated the efficacy of picibanil sclerotherapy for benign neck cysts. Materials and methods: We retrospectively reviewed 53 patients(27 males, 26 females) who had undergone sclerotherapy with picibanil for benign neck cysts such as ranula, lymphangioma, thyroglossal duct cyst and branchial cyst. Information was gathered with respected to age, sex, number of injections, side effect and outcome of treatment. All patients were treated with intralesional aspiration of cystic contents and injection of picibanil, and followed on neck ultrasonography or neck CT. Results: 53 patients received sonoguided sclerotherapy using picibanil(OK-432). 31 patients(41.3%) showed total shrinkage, near total shrinkage(more than 90% of volume) in 7 patients(9.3%), marked shrinkage(more than 70%) in 5 patients(6.6%) and partial shrinkage(less than 70%) in 17 patients. 15 patients(20%) reaveled no response and 8 patients showed recurrences with repeated sclerotherapy. The side effects of therapy were observed by symptoms such as fever, localized pain and odynophagia. However, these complications disappeared after several days in all cases. Conclusions: We recognized that picibanil(OK-432) sclerotherapy for benign neck cyst is a safe and effective procedures as a primary treatment before considering surgery.

  • PDF

A Leverage Strategy of the Cyber warfare Security Policy Based on systems Thinking (시스템 사고를 이용한 사이버전 보안 정책 레버리지 전략 연구)

  • Yang, Ho-Kyung;Cha, Hyun-Jong;Shin, Hyo-Young;Park, Ho-Kyun;Ryou, Hwang-Bin
    • Convergence Security Journal
    • /
    • v.13 no.4
    • /
    • pp.77-83
    • /
    • 2013
  • As the network composed of numerous sensor nodes, sensor network conducts the function of sensing the surrounding information by sensor and of the sensed information. The concept of the battlefield is also changing to one that includes not only physical spaces but all areas including the networks of the nation's key industries and military facilities, energy facilities, transportation, and communication networks. In light of the changing warfare in terms of how it is conducted and what form it takes, the Korea military has to seek ways to effectively respond to threats of cyber warfare. In the past, although partial strategies on cyber warfare were studied, no research was done through the overall system flow. In this paper, key variables related to cyber warfare security are classified into personnel, management, and technology. A simple model and an extended model are suggested for each area, and based on the technology area of the extended model, formal methods are used to verify the validity and a detailed response strategy is suggested according to the identified leverage.

A case of Primary Malignant Fibrous Histiocytoma of the Diaphragm (횡경막에 발생한 악성 섬유종 조직구종 1예)

  • Shim, Jaejun;Cho, Yongseon;Kim, Hyun-Sook;Choi, Hye-Sook;Choi, Cheon Woong;Yoo, Jee Hong;Kang, Hong Mo;Yang, Moon Ho
    • Tuberculosis and Respiratory Diseases
    • /
    • v.54 no.6
    • /
    • pp.645-650
    • /
    • 2003
  • A malignant fibrous histiocytoma (MFH) is a major subset of soft tissue sarcomas, which occurs principally on the extremities or in the retroperitoneum, as well as on the head and neck of elderly patient. However, it is an extremely rare event when a MFH occurs primarily in the diaphragm of a young people. A 25-year-old woman visited our hospital complaining of right chest pain. The chest X-ray showed a diaphragmatic mass. An exploratory thoracotomic biopsy revealed a primary MFH of the diaphragm. The patient was treated with combined chemotherapy consisting of ifosfamide and doxorubicin. A partial response was seen after 6 cycles of chemotherapy. However, she died of brain metastasis 12 months after the diagnosis.

A Study for Enterprise Type Realtime Information Security Management System (기업의 상시 보안관리 체계 연구)

  • Noh, Shi-Yeong;Lim, Jong-in
    • Journal of the Korea Institute of Information Security & Cryptology
    • /
    • v.27 no.3
    • /
    • pp.617-636
    • /
    • 2017
  • Many businesses have adopted the standard security management structure such as ISO27001 and K-ISMS for strengthening business's security management structure to protect their core information assets and have acquired partial output from such effort. However, many risk factors such as recent advances in Information Technology and evolution of intrusion methods have increased exponentially requiring the businesses to response even more quickly with better accuracy. For such purpose, a study of 'Real Time Security Management Structure for Business' based on security management process optimization, defining a set of security index for managing core security area and calculation of risk indices for precognition of intrusion risk area has been made. Also, a survey on opinions of an expert panel has been conducted. The effectiveness of studied structure was analyzed using AHP method as well. Using this study, security personnels of a company can improve efficiency of the preemptive responsive and quicker measure from the current security management structure.

Design of Class-II Partial-Response System above the Nyquist Rate (나이퀴스트 속도를 초과하는 제2종 부분응답 시스템의 설계)

  • 오용선
    • Journal of the Korea Institute of Information and Communication Engineering
    • /
    • v.2 no.1
    • /
    • pp.27-35
    • /
    • 1998
  • In this paper, we propose a novel spectral-chopping model of Class-II$(1+D)^2$ -PRS system which reveals improved spectral efficiency. We build up the model having spectrum chopped by the amount of Nyquist over-rate, and then compare its characteristics with the conventional model in both the time-domain and the frequency-domain. When the transmission system operates above the Nyquist rate, the new model has better performance than the conventional PRS using its inherent speed-tolerance. According to our investigations, Class-II PRS shows more excellent effect in the spectral-chopping method than Class- I and W types analyzed previously. We ascertain that the over-rate of 26.675 obtained by the inherent speed-tolerance could be improved upto 40% using spectrum-truncation. These effects come from the fact that the raised-cosine spectrum of Class-II PRS has smaller Boss of frequency component and energy than any other types for the same amount of truncation. In order to validate these theoretical results, we present their sidelobe-trends confirming cancellation effects at the sampling instants and some experimental results showing their patterns of eye-openings and spectra.

  • PDF

Fundamental Investigation of Non-invasive Determination of Glucose by Near Infrared Spectrophotometry (근적외선 분광법을 이용한 비침투적 혈당 분석법 개발에 관한 기초 연구)

  • Kim, Hyo J.;Woo, Young A.;Chang, Soo H.;Cho, Chang H.;Cantrell, Kevin;Piepmeier, Edward H.
    • Analytical Science and Technology
    • /
    • v.11 no.1
    • /
    • pp.47-53
    • /
    • 1998
  • This study is to improve the diagnosis of diabetes mellitus and the self-monitoring of blood glucose in people with diabetes by providing a non-invasive method of monitoring blood glucose. A near-infrared (NIR) spectrophotometer was used to measure absorption spectra of 80 glucose samples ranges from 1 mg/dL to 200 mg/dL, and shows the standard error of prediction 1.8 mg/dL. Also, to investigate the effect of interference in blood, NaCl and sand were added in glucose and found the standard error of prediction of 2.8 mg/dL and 3.8 mg/dL, respectively. A new and more accurate calibration system for the spectrophotometer was developed from systematic study of light scattering, which cause nonlinear spectrophotometer response.

  • PDF

PRML detection scheme with modified trellis for a MTR code (MTR 코드를 위한 변형된 트렐리스를 갖는 PRML 검출 방법)

  • Lee Joo hyun;Lee Jea jin
    • The Journal of Korean Institute of Communications and Information Sciences
    • /
    • v.29 no.12C
    • /
    • pp.1601-1605
    • /
    • 2004
  • When codeword sequence has two or less successive transitions, the performance of 4th-order partial response maximum-likelihood (PRML) detector can be improved. However, the code leads to an unacceptable loss of performance due to the low code rate. For a rate 718 code that MTR constraint (i) of each codeword is limited to 2, and j is allowed to be 3 when codewords are connected, we modified the trellis of PRML detector to combine j=2 with J=3. We confirmed that the rate 718 coded 4th-order PRML detection with combined trellis achieves the SNR gain more than 2dB compared to the rate 819 coded 4u_order PRML detection at 10-s BER in high-density longitudinal or perpendicular magnetic recording systems.

A study on physical activities by applying a social cognitive theory (사회인지이론을 적용한 신체활동에 관한 문헌고찰)

  • Han, Eun-Ok;Moon, In-Ok
    • The Journal of Korean Society for School & Community Health Education
    • /
    • v.6
    • /
    • pp.117-126
    • /
    • 2005
  • This study attempted to extract a suggestive point to help the design of a program, which is used to promote physical activities, by applying a social cognitive theory based on literature review on the physical activity based on a social cognitive theory. This study considers 10 journal articles that used a social cognitive theory, physical activity, and exercise as the major variable using the EBSCOhost Academic Search Premier and Educator's Reference Desk (ERIC). The type of papers was analyzed using a certain criterion, which can be configured according to the number of each year's papers, characteristics of research subjects, application type of a social cognitive theory, and classification of the application of objects in a social cognitive theory. The characteristics of each year's papers presented no specific characteristics for each year's papers, but the study in 2004 especially presented a high level. The characteristics of research subjects presented four highest cases in the case of the college student, and there were zero cases for children. The application type of studies on physical activities using a social cognitive theory can be largely classified as three types. The results of the measurement using a sectional investigation for SCT objects were 2 cases, the application of SCT for promoting physical activities was 1 case, and the demonstration of evaluation for the effect of SCT objects presented 8 highest cases. Although the social cognitive theory in the characteristics of the classification of object applications can be classified as 10 objects, there were no cases that used 10 all objects, partial applications of the object were measured in 8 studies, and two cases presented no detailed considerations on the object. Most of studies used a part of the object where the application of self-efficacy were measured by 8 highest cases. In addition, there were no measurements on the situation, observation learning, answer and response, and self-management. The elements of attitude, cognitive activity, self-efficacy, and handicaps among the SCT object were commonly used, and studies that the self-efficacy largely affects on the promotion of physical activities presented the main current.

  • PDF

Partial Purification of Lectin from Mycoparasitic Species of Trichoderma

  • Singh, Tanuja;Saikia, Ratul;Arora, Dilip K.
    • The Plant Pathology Journal
    • /
    • v.21 no.4
    • /
    • pp.301-309
    • /
    • 2005
  • Trichoderma species/isolates exhibited varied degree of agglutination on sclerotial (Sc) and hyphal (Hy) surface of Macrophomina phaseolina. The agglutination efficiencies on Sc and Hy ranged from $11\;to\;57\%$. Isolates of T. harzianum (Th) and T. viride (Tv) showed greater agglutination on Sc ($23-57\%$) and Hy ($16-47\%$). Different enzymes (trypsin, pepsin, proteinase k, a-chymotrypsin, lyticase and glucosidase) and inhibitors (tunicamycin, cycloheximide, brefeldin A, sodium azide, dithiothreitol and SDS) reduced the agglutination potential of conidia of Th-23/98 and Tv-25/98; however, the extent of response varied greatly in different treatments. Different fractions of Th-23/98 and Tv-25/98 exhibited haemagglutinating reaction with human blood group A, B, AB and O. Haemagglutinating activity was inhibited by different sugars and glycoproteins tested. Crude haemagglutinating protein from outer cell wall protein fraction of Th-23/98 and Tv-25/98 were eluted on Sephadex G-100 column. Initially Th-23/98 and Tv-25/98 exhibited two peaks showing no agglutination activity; however, lectin activity was detected in the third peak. Similar to crude lectin, the purified lectin also exhibited haemagglutinating activity with different erythrocyte source. SDS-PAGE analysis of partially purified lectin revealed single band with an estimated molecular mass of 55 and 52 kDa in Th-23/98 and Tv-25/98, respectively. Trypsin, chymotrypsin and b-1,3-glucanase totally inhibited lectin activity. Similarly, various pH also affected the haemagglutinating activity of Th-23/98 and Tv-25/98. From the present observations, it can be concluded that the recognition/attachment of mycoparasite (T. harzianum and T. viride) to the host surface (M. phaseolina) may be most likely due to lectin-carbohydrate interaction.

Initial experience with intra-articular 188Re-tin colloid as a "radiation synovectomy" agent in various joints

  • Shinto, Ajit S;Indira, VU;Kamaleshwaran, KK;Banka, Vinay Kumar;Aswathy, KK;Thirumalaisamy, SG;Rajamani, V;Mallia, Madhav;Banerjee, Sharmila
    • Journal of Radiopharmaceuticals and Molecular Probes
    • /
    • v.1 no.2
    • /
    • pp.109-117
    • /
    • 2015
  • Radiation synovectomy has been proposed as a promising palliative therapy for recurrent joint effusions for the last two or three decades. Ionizing radiations emitted by intrarticularly administered radiolabelled colloids. The aim of this study was to assess the effectiveness of radiation synovectomy (RSV) using $^{188}Re$-tin colloid in the treatment of recurrent joint effusions and chronic synovitis of knee joints. Three phase bone scan was acquired for the concerned joint prior to radiosynovectomy. $^{188}Re$-tin colloid was prepared as per the reported protocol. 9 patients, diagnosed with rheumatoid arthritis and suffering from chronic resistant synovitis of the knee, ankle or elbow joints were administered the radiopharmaceuticals, checked for radiochemical purity >95% by intraarticular route. A whole body scan was acquired 2 h post-radiosynovectomy. In all the 9 treatments, no leakage to non-target organs was visible in the whole body scan. Static scans of the joint revealed complete retention of $^{188}Re$-tin colloid in the joints post administration of the agent. Clinically all patients exhibited a complete or partial response. RSV with $^{188}Re$-tin colloid was safe and effective in patients with chronic synovitis of rheumatoid origin.