• Korean Journal of Radiology
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• v.20 no.4
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• pp.589-598
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• 2019

Objective: To evaluate whether data acquired from perfusion computed tomography (PCT) parameters can aid in the prediction of treatment outcome after palliative chemotherapy in patients with unresectable advanced gastric cancer (AGC). Materials and Methods: Twenty-one patients with unresectable AGCs, who underwent both PCT and palliative chemotherapy, were prospectively included. Treatment response was assessed according to Response Evaluation Criteria in Solid Tumors version 1.1 (i.e., patients who achieved complete or partial response were classified as responders). The relationship between tumor response and PCT parameters was evaluated using the Mann-Whitney test and receiver operating characteristic analysis. One-year survival was estimated using the Kaplan-Meier method. Results: After chemotherapy, six patients exhibited partial response and were allocated to the responder group while the remaining 15 patients were allocated to the non-responder group. Permeability surface (PS) value was shown to be significantly different between the responder and non-responder groups (51.0 mL/100 g/min vs. 23.4 mL/100 g/min, respectively; p = 0.002), whereas other PCT parameters did not demonstrate a significant difference. The area under the curve for prediction in responders was 0.911 (p = 0.004) for PS value, with a sensitivity of 100% (6/6) and specificity of 80% (12/15) at a cut-off value of 29.7 mL/100 g/min. One-year survival in nine patients with PS value > 29.7 mL/100 g/min was 66.7%, which was significantly higher than that in the 12 patients (33.3%) with PS value ≤ 29.7 mL/100 g/min (p = 0.019). Conclusion: Perfusion parameter data acquired from PCT demonstrated predictive value for treatment outcome after palliative chemotherapy, reflected by the significantly higher PS value in the responder group compared with the non-responder group.

• Structural Engineering and Mechanics
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• v.75 no.3
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• pp.357-367
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• 2020

The objective of this article is investigation of dynamic response of thick multilayer functionally graded (FG) beam under generalized dynamic forces. The plane stress problem is exploited to describe the constitutive equation of thick FG beam to get realistic and accurate response. Applied dynamic forces are assumed to be sinusoidal harmonic, sinusoidal pulse or triangle in time domain and point load. Equations of motion of deep FG beam are derived based on the Hamilton principle from kinematic relations and constitutive equations of plane stress problem. The numerical finite element procedure is adopted to discretize the space domain of structure and transform partial differential equations of motion to ordinary differential equations in time domain. Numerical time integration method is used to solve the system of equations in time domain and find the time responses. Numerical parametric studies are performed to illustrate effects of force type, graduation parameter, geometrical and stacking sequence of layers on the time response of deep multilayer FG beams.

• Communications for Statistical Applications and Methods
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• v.13 no.2
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• pp.273-283
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• 2006

In bioassay, the response curve is usually assumed monotone increasing, but its exact form is unknown, so it is very difficult to select the proper functional form for the parametric model. Therefore, we should probably use the nonparametric regression model rather than the parametric model unless we have at least the partial information about the true response curve. However, it is well known that the nonparametric regression estimate is not necessarily monotone. Therefore the monotonizing transformation technique is of course required. In this paper, we compare the finite sample properties of the monotone transformation methods which can be applied to the local linear quasi-likelihood response curve estimate.

• Journal of Fisheries and Marine Sciences Education
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• v.27 no.6
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• pp.1546-1555
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• 2015

This study was performed to analyze the item characteristics of competency inventory for designer (CID), which Gil (2011) developed for measurement of design competency. To accomplish the purpose of this study, general partial credit (GPC) model based on polytomous item response theory was applied. The findings were as follows: First, CID is a reliable instrument for measuring design competency. Second, most items of CID have low item discrimination and average item difficulty according to the GPC model. Especially, there are some problems to have low item discrimination in view of validation. To improve the goodness of CID, we will need to examine why CID has low item discrimination.

• Journal of Electrical Engineering and Technology
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• v.2 no.3
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• pp.396-400
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• 2007

A novel technique has been proposed and related experimental works have been performed in order to detect the partial discharges and the location of the possible defects introduced into the Gas Insulated Switchgear. For this purpose, a prototype HY Pockels sensor has been developed and then employed in order to investigate its field applicability for finding the location of the defects using a 170kV GIS mock-up. Our proposed sensor enables us to measure the electric field variation due to the PD occurrence. In addition, the different PD patterns are observed, which might be dependant on the location and the distance of the sensor with respect to the PD source. Throughout this work, its linear response has been proved to be admissible as a function of the applied voltage. And also the position of the PD source might be distinguished by comparing the PD patterns.

• Korean Journal of Veterinary Service
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• v.18 no.2
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• pp.182-188
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• 1995

Hemodynamic values were assessed in cows with naturally mastatis. hemodynamic tests included WBC, RBC, PCV, Hemoglobin, Monocyte, Eosinophil, Neutrophil, Lymphocyte, and prothrombin time, activated partial thromboplastin time, thrombin time, fibrinogen, platelet, antithrombin-III, and plasminogen activities. Significant changes were observed in the mean values of most analytses : WBC, monocytes, eosinophil, neutrophil were increased and Iymphocyte were decreased. prothrombin time was increased： activated partial thromboplastin time, thrombin time. increased : activated partial thromboplastin time, thrombin time, fibrinogen concentration, plasminogen activity and platelet concentration were decreased : and RBC, PCV, hemoglobin and antithrombin-III activity were unchanged, compared with normal mean values. Thesse data indicated activation of hemodynamic mechanisms, initiated either directly by bacteria produced endotoxin of secondaly inflammatory mediators produced in response to caused bacteria and naturally acquired mastitis was very similar to the experimental endotoxin-induced mastitis.

• Near Infrared Analysis
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• v.1 no.2
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• pp.1-8
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• 2000

Using the net analyte signal, hybrid linear analysis was proposed to predict chemical concentration. In this paper, we select a sample from training set and apply orthogonal signal correction to obtain an improved pseudo unit spectrum for hybrid least analysis. using the mean spectrum of a calibration training set, we first show the calibration by hybrid least analysis is effective to the prediction of not only chemical concentrations but also physical property variables. Then, a pseudo unit spectrum from a training set is also tested with and without orthogonal signal correction. We use two data sets, one including five chemical concentrations and the other including ten physical property variables, to compare the performance of partial least squares and modified hybrid least analysis calibration methods. The results show that the hybrid least analysis with a selected training spectrum instead of well-measured pure spectrum still gives good performances, which is a little better than partial least squares.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2002.05c
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• pp.160-164
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• 2002

A special discharge cell containing a free conducting particle was used to generate the discharges in $SF_6$. The analog bandwidth of the measurement system exceeded 5 GHz. The measured signals were processed to compensate for the response of the measurement system. The discharge current rise time was in the range of 70 ps, while its full-width half-maximum was 120 ps. Single and double current pulses of positive and negative polarities were measured. Likewise, these pulses were compared with the measurement obtained using a conventional partial discharge detector of the IEC60270 type

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 1996.10a
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• pp.275-281
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• 1996

In order to examine the validity of an asymptotic solution obtained from the method of multiple scales, we investigate a third-order subharmonic resonance response of a bar constrained by a nonlinear spring to a harmonic excitation. The motion of the bar is governed by a linear partial differential equation with a nonlinear boundary condition. The nonlinear boundary value problem is solved by using the finite difference method. The numerical solution is compared with the asymptotic solution.

• Structural Engineering and Mechanics
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• v.75 no.4
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• pp.497-506
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• 2020

CA mortar layer disengagement will give rise to the overall structural changes of the track and variation in the vibration form of the ballastless track. By establishing a vehicle-track-viaduct coupling analysis and calculation model, it is possible to analyze the CRTS-I type track structure vibration response while the track slab is disengaging with the power flow evaluation method, to compare the two disengaging types, namely partial contact loss at one edge beneath track slab and partial contact loss at midpoint beneath track slab. It can also study how the length of disengaging influences the track structures vibration power. It is showed that when the partial contact loss beneath track slab, and the relative vibration energy level between the rail and the track slab increases significantly within [10, 200]Hz with the same disengaging length, the partial contact loss at one edge beneath track slab has more prominent influence on the vibration power than the partial contact loss at midpoint beneath track slab. With the increase of disengaging length, the relative vibration energy level of the track slab grows sharply, but it will change significantly when it reaches 1.56 m. Little effect will be caused by the relative vibration energy level of the viaduct. The partial contact loss beneath the track slab will cause more power distribution and transmission between the trail and track slab, and will then affect the service life of the rail and track slab.