• 제목/요약/키워드: part family

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Translation and Transcription: the Dual Functionality of LysRS in Mast Cells

  • Yannay-Cohen, Nurit;Razin, Ehud
    • Molecules and Cells
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    • 제22권2호
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    • pp.127-132
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    • 2006
  • In the post genome project era, it is well established that the human genome contains a smaller number of genes than expected. The complexity found in higher organisms can be explained if proteins are multifunctional. Indeed, recent studies are continuing to reveal proteins that are capable of a broad repertoire of functions. A good paradigm for multifunctionality can be found in the amino-acyl tRNA synthetases (aaRSs), an ancient conserved family of proteins. This unique family, which is comprised of 20 different enzymes, is well known for its participation in protein synthesis. Several studies have described numerous examples of these "housekeeping" proteins taking part in extensive critical cellular activities. In this review, we focus on a member of that family, lysyl-tRNA synthetase (LysRS), which has been shown to have a dual functionality. In addition to its contribution to the translation process, LysRS also takes part in the regulation of MITF and USF2 target genes. This phenomenon was first described in mast cells.

건강가정지원센터의 교육사업 담당 건강가정사의 직무와 역량에 관한 연구 (A Study for the Job and Competency of Healthy Family Supporter in charge of Educational work in Healthy Family Support Center)

  • 이윤정
    • 가족자원경영과 정책
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    • 제12권4호
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    • pp.79-102
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    • 2008
  • The aims of this article were to examine the basic law, contents and concept of educational program for healthy family and provide the jobs and competency of healthy family supporter for educational work. The research objects were 53 healthy family supporters for educational work inclusive of full-time and part-time position. They was analyzed through the survey. The process of research consisted of two parts. One was to suggest their jobs and requirements, the other were to offer their core competency and area for improvement. First, the jobs of healthy family supporters for educational work were the planning and valuation of program. The requirements for the performance of their duties are having a bachelor's degree or a master's degree, career for 1-3years, and a certificate of qualification of healthy family supporters, social worker and family counselor. Second, their competencies were the understanding of education for family life, management for healthy family support center, planning and valuation of educational program, a theory of counsel, community networking, ability of documentation, sociality, communication skill, the ability of solving the problem, the adaptation of various environments, receptiveness, positiveness and so on.

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An Investigation of Family Entrepreneurship in Ownership and Firm Performance: Empirical Evidence from Pakistan

  • KHAN, Muddasir Riaz;TARIQ, Yasir Bin
    • The Journal of Asian Finance, Economics and Business
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    • 제9권5호
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    • pp.63-73
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    • 2022
  • In today's financial economics literature, the impact of innovative family ownership and management on firm performance is a prominent concern. In this study, the existence of family firms in the listed sector of Pakistan's economy is investigated. The objective of this study is to examine the performance-oriented relationship of family ownership and active involvement of family member at the CEO position. The theoretical perspectives that underpin this research are agency and stewardship. This analysis used a sample of 315 publicly traded companies from 2009 to 2019. The study's primary independent variables include family influence on ownership and family CEO. Financial performance is the dependent variable that is divided into accounting and market measures. The proxy for accounting measure is return on asset and proxy for market measure is Tobin's Q. This study employs univariate and balanced panel data analysis. For robustness of the analysis random-effects GLS regression is carried out. The empirical results show that that Family Firms outperform Non-Family Firms both in terms of accounting and market measures. In the later part family CEOs firms outperform the firms that have either insider or outsider non-family CEOs. This superior performance is subjected to the positive and statistically significant association between family ownership, management, and financial performance.

건강가정지원센터의 운영모델에 관한 기초조사 - 조직과 평가를 중심으로 - (A Fundamental Survey Study for the Organizational System and Evaluation Strategies of Healthy Family Support Centers)

  • 원소연;장진경
    • 대한가정학회지
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    • 제43권7호
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    • pp.129-145
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    • 2005
  • The Healthy Family Act was established in 2004 to prevent problems of the family and increase thehealthy characteristic of the general family. According to this Act, Healthy Family Support Centers (HFSCs) were founded as a new part of the family welfare institution. The purpose of HFSCs is providing various welfare services to enhance the health and well-being of families in the community. This study investigated the organizational system and evaluation strategies of HFSCs. This research comprised a descriptive study of the organizational system and evaluation strategies of HFSC. The study sample consisted of 217 faculty and field workers. Data were collected from December 2004 to January 2005 and analyzed by frequencies, mean, standard deviation and ANOVA. The results were as follows. First, HFSC's organization should consist of family education, family counseling, family culture-marketing, and network teams. Second, healthy family specialists should have a national certificate of qualifications also they should have more than master's degree level. Third, evaluation of HFSCs should be adapt an incentive system.

정신지체아 부.모의 스트레스와 가족결합력 (The Perceived Stresses and Family Strengths by Fathers and Mothers having Mentally Retarded Children)

  • 김나영;윤호열
    • 대한가정학회지
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    • 제38권7호
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    • pp.53-65
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    • 2000
  • This study is for examining the differences of perceived stresses and family strengths between the parents according to socio-demographic backgrounds(age, educational level, income and the degree of disorder) of the parents having mentally retarded children. The results were as follows. First, in the overall perceived stress level, there was no difference between fathers and mothers, but when compared in stress areas, fathers experience more distresses in general interpersonal areas than mothers. Fathers also shows differences according to the degrees of their income and their perception about disorder compared with mothers showing differences according to the degree of income. Second, there were no differences in family strengths perceived by both fathers and mothers, but were significant differences according to the level of education and income. Another words, higher the education and income level, higher is their family strengths level. Third, there were positive correlations between the perceived stresses and family strengths, and significant differences in family strengths according to the stress level(higher/lower part of the group). In other words, when the perceived stress level is high, the level of perceived family strengths is low.

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전라북도 거주 기혼여성의 가족생활실태조사(II): 가족생활문제 및 해결방안을 중심으로 (Family Life Issues of Married Womens in Chonbuk: Focused on Family Life Problems & Solution)

  • 이성희
    • 대한가정학회지
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    • 제38권8호
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    • pp.53-68
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    • 2000
  • This study examines family life problems & solution of married women in Chonbuk area as a part of study on family life Issues. Data were collected by questionnaires. The sample consisted of 1142 married women. The major findings were summarized as follows : (1) The degree of recognition about family life problem is rated economic life > woman's parents-in-law> woman's real parents> spouse> children related problems. (2) In the family conflict solution types, the most used types is a rational. (3) The degree of recognition about the family violence is rated abusive languages of husband>husband behavior under the influence of alcohol wife's child abuse>husband's child abuse>abusive languages of wife>battered wife. (4) The kins are still considered the primary source for functions of personal support. Also, the needs for the children related equipments is higest among the public support equipments.

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취업모 일만족도에 영향을 미치는 요인 분석: 전일제와 시간제 비교 (Influential Factors for Job Satisfaction: A Comparison of Part-Time and Full-Time Female Employees with Children)

  • 정영순;어윤경;임유진
    • 한국사회정책
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    • 제19권3호
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    • pp.215-245
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    • 2012
  • 본 연구는 18세 이하의 자녀를 둔 배우자 있는 기혼여성 임금근로자를 전일제와 시간제로 구분하여, 일만족도에 영향을 미치는 경로구조가 두 집단에 동일한지, 경로계수가 두 집단 간 차이를 보이는지를 비교분석하였다. 복수모집단 동시분석 결과, 경로모형은 근무형태가 다른 두 집단에게 적합하나 경로계수는 두 집단 간 유의미한 차이가 있는 것으로 밝혀졌다. 실제로 직접효과를 보면, 본인소득, 사업장 규모, 남편 일지지, 일가정 대립은 두 집단의 일 만족도에 공통적으로 영향을 미쳤으나 건강상태는 전일제 취업모의 일만족도에만 영향을 미치는 것으로 밝혀졌다. 간접효과에서도, 가정일 대립은 공통적으로 두 집단의 일만족도에 간접적으로 영향을 미쳤으나, 건강상태는 전일제에게만, 미취학자녀와 본인소득은 시간제에게만 일만족도에 간접적으로 영향을 미치는 것으로 밝혀졌다. 이러한 연구결과는 자녀를 둔 기혼여성 임금근로자의 일만족도를 향상시키기 위해서는 근무형태별로 차별화된 대책이 마련되는 것이 효과적임을 시사해주고 있다.

Clustering Parts Based on the Design and Manufacturing Similarities Using a Genetic Algorithm

  • Lee, Sung-Youl
    • 한국산업정보학회논문지
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    • 제16권4호
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    • pp.119-125
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    • 2011
  • The part family (PF) formation in a cellular manufacturing has been a key issue for the successful implementation of Group Technology (GT). Basically, a part has two different attributes; i.e., design and manufacturing. The respective similarity in both attributes is often conflicting each other. However, the two attributes should be taken into account appropriately in order for the PF to maximize the benefits of the GT implementation. This paper proposes a clustering algorithm which considers the two attributes simultaneously based on pareto optimal theory. The similarity in each attribute can be represented as two individual objective functions. Then, the resulting two objective functions are properly combined into a pareto fitness function which assigns a single fitness value to each solution based on the two objective functions. A GA is used to find the pareto optimal set of solutions based on the fitness function. A set of hypothetical parts are grouped using the proposed system. The results show that the proposed system is very promising in clustering with multiple objectives.

THE ANALYSIS OF A STAR CLUSTER FAMILY IN THE NORTHERN PART OF CARINA NEBULA

  • AYU, RAMADHANI PUTRI;PRIYATIKANTO, RHOROM;ARIFYANTO, M. IKBAL;ROMADHONIA, RISKA WAHYU;HILMI, MIFTAHUL;FITRIANA, ITSNA KHOIRUL;WULANDARI, HESTI R.T.
    • 천문학논총
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    • 제30권2호
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    • pp.275-278
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    • 2015
  • We studied a cluster family in the northern part of the Carina Nebula (NGC 3372) a group of clusters near NGC 3324 (Tr 15, NGC 3293, Loden 165, Loden 153 and IC 2581). We used data from UCAC4 to determine the cluster's membership and the near infrared CMDs of each cluster. We analyzed the spatial density and elongation as a function of radius for each cluster and found a possible interaction between NGC 3293 and Loden153. However, the shape distortion of NGC 3324 cannot be evaluated because of the inhomogenity in the coverage of UCAC4 in the east part of NGC 3324.