• Title/Summary/Keyword: parameter sensitivity

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Analysis of Variables Affecting on Customer Loyalty by Market Segments for the Korean Open Air Market Using Mixture Regression Model (Mixture Regression Model을 이용한 재래시장의 세분집단별 고객충성도에 미치는 영향 변수 분석)

  • Kim, Jong-Kook;Park, Youn-Jae;Park, Ju-Young;Choi, Ja-Young
    • Journal of Distribution Research
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    • v.12 no.4
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    • pp.1-25
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    • 2007
  • The purpose of this study is to provide the strategic implication of the Korean open air market by examining the factors affecting customer loyalty for various market segments as their competitive environment becomes more turbulent. We have undertaken empirical research that uses the methodology of a mixture regression modeling, as a way to ascertain the determinants of customer loyalty toward the Korean open air market, which should form the base of strategy for each segment. We construct a mixture regression model which uses perceived the Korean open air market value dimensions as explanatory variables, an income as a covariate variable, and a customer loyalty as a dependent variable. The analysis of results show that customers are statistically divided into four segments: 'Accessibility'(33.7%), 'Price'(29.7%), 'Shopping environment,'(22.0%), and 'Merchandising,'(14.5%) groups. The findings also showed that parameter estimates are different for each group, which indicates that the sensitivity to changes in the Korean traditional market perceived value and the income variable affecting customer loyalty vary among segments.

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Transfer System using Radial Electrodynamic Wheel over Conductive Track (래디얼 동전기 휠을 이용한 전도성 트랙 위에서의 이송 시스템)

  • Jung, Kwang Suk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.11
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    • pp.794-801
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    • 2017
  • When a radial wheel is placed so as to partially overlap a conductive plate and rotated, a lift force is generated on the wheel, a thrust force along the edge, and a lateral force which tends to reduce the overlap region. When several of these wheels are combined, it is possible to realize a system in which the stability of the remaining axes is ensured, except in the traveling direction. To validate the overall characteristics of the multi-wheel system, we propose a transfer system levitated magnetically using radial electrodynamic wheels. The proposed system is floated and propelled by four wheels and arranged in a structure that allows the thrusts generated by the front and rear wheels to offset each other. The dynamic stability of the wheel and the effect of the pole number on the three-axial forces are analyzed by the finite element method. At this time, the thrust and levitation force are strongly coupled, and the only factor affecting them is the wheel rotation speed. Therefore, in order to control these two forces independently, we make use of the fact that the ratio of the thrust to the levitation force is proportional to the velocity and is independent of the size of the gap. The in-plane and out-of-plane motion control of the system is achieved by this control method and compared with the simulation results. The experimental results show that the coupled degrees of freedom can be effectively controlled by the wheel speed alone.

An efficient 2.5D inversion of loop-loop electromagnetic data (루프-루프 전자탐사자료의 효과적인 2.5차원 역산)

  • Song, Yoon-Ho;Kim, Jung-Ho
    • Geophysics and Geophysical Exploration
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    • v.11 no.1
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    • pp.68-77
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    • 2008
  • We have developed an inversion algorithm for loop-loop electromagnetic (EM) data, based on the localised non-linear or extended Born approximation to the solution of the 2.5D integral equation describing an EM scattering problem. Source and receiver configuration may be horizontal co-planar (HCP) or vertical co-planar (VCP). Both multi-frequency and multi-separation data can be incorporated. Our inversion code runs on a PC platform without heavy computational load. For the sake of stable and high-resolution performance of the inversion, we implemented an algorithm determining an optimum spatially varying Lagrangian multiplier as a function of sensitivity distribution, through parameter resolution matrix and Backus-Gilbert spread function analysis. Considering that the different source-receiver orientation characteristics cause inconsistent sensitivities to the resistivity structure in simultaneous inversion of HCP and VCP data, which affects the stability and resolution of the inversion result, we adapted a weighting scheme based on the variances of misfits between the measured and calculated datasets. The accuracy of the modelling code that we have developed has been proven over the frequency, conductivity, and geometric ranges typically used in a loop-loop EM system through comparison with 2.5D finite-element modelling results. We first applied the inversion to synthetic data, from a model with resistive as well as conductive inhomogeneities embedded in a homogeneous half-space, to validate its performance. Applying the inversion to field data and comparing the result with that of dc resistivity data, we conclude that the newly developed algorithm provides a reasonable image of the subsurface.

The Preoperative Diagnosis of Thyroid Cancer in $^{18}F$-FDG PET/CT Dual Time Imaging of SUV and Evaluation of Radioactivity Measurement (갑상선암 수술 전 진단목적의 $^{18}F$-FDG PET/CT Dual Time Point영상에서 SUV값과 방사능 농도 측정법의 유용성 평가)

  • Lee, Hyun-Kuk;Khang, Hyun Soo;Yang, Seoung-Oh;Han, Man-Seok
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.2
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    • pp.99-105
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    • 2012
  • Purpose : This study is designed to compare two parameters reflecting $^{18}F$-FDG uptake, SUV and radioactivity, for diagnosis of thyroid cancer in dual time $^{18}F$-FDG PET/CT imaging and to find which parameter is more useful to decide whether the tumor is malignant or not. Materials and Methods : We performed retrospective study for 40 patients. All patients are diagnosed as primary thyroid cancer and examined $^{18}F$-FDG PET/CT. First, we got the dispersion of scattering beam of neck and lung apex to set a background and compared each dispersion, mean value, standard deviation of maxSUV and radioactivity. Also, mean maxSUV, ${\Delta}maxSUV$, ${\Delta}maxBq$/ml(%) and radioactivity between groups according to lesion's size based on biopsy are compared with independent-sample t-test. Results : the values that were from maxSUV and radioactivity measurement technique were compensated and calculated to practical values for mean comparison and patients were divided to two groups based on tumor size, Group1 ($size{\leq}1$ cm, n=21), Group2 (size>1 cm, n=19) for accurate comparison. In Group1, maxSUV (semi-quantitative analysis) was increased from $5.64{\pm}5.85$ (1.89~17.84) at first image to $5.90{\pm}5.01$ (1.95~18.22) at second image and radioactivity (Bq/ml) (quantitative analysis) showed similar increase from $5.93{\pm}6.38$ (2.50~16.75) at first image to $6.01{\pm}5.25$ (2.66~16.58) at second image. In Group2, TFmaxSUV was $10.54{\pm}14.36$ (2.54~33.89) in true first image, TSmaxSUV was $9.85{\pm}12.88$ (2.62~26.20) in true second image separately. The maxSUV showed a significant difference in the mean comparison between the two groups (p=0.035) But, mean radioactivity (Bq/ml) was $5.93{\pm}6.38$ (4.81~40.99) in true first image, $6.01{\pm}5.25$ (4.51~36.93) in true second image and didn't show a significant difference statistically (p=0.126) Conclusion : In diagnosis of thyroid tumor, SUV and radioactivity depending on $^{18}F$-FDG uptake showed high similarity with coefficient of determination (R2=0.939) and malignant evaluation results using dual time also showed similar aspect. Radioactivity for evaluation of malignant tumor didn't show better specificity or sensitivity than maxSUV.

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The Usefulness of Initial Arterial Base Deficit in Trauma Patients (내원 초기에 측정한 외상환자의 동맥혈 염기결핍의 유용성)

  • Lee, Eun Hun;Choi, Jae Young;Choi, Young Cheol;Hwang, Seong Youn
    • Journal of Trauma and Injury
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    • v.19 no.1
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    • pp.67-73
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    • 2006
  • Purpose: The arterial base deficit (BD) has proven to be useful in the evaluation and management of trauma patients. Indicators such as the Triage-Revised Trauma Score (t-RTS) and the systemic inflammatory response syndrome (SIRS) score have been used as triage tools for emergency trauma patients in Korea. The purpose of this study was to assess the usefulness of the initial BD in predicting injury severity and outcome in the trauma population. Methods: The medical records of 308 consecutive trauma patients admitted to the Emergency Center of Masan Samsung Hospital from January 2004 to December 2004 were carefully examined prospectively and retrospectively, and 291 patients were selected as subjects for this research. The SIRS score and the t-RTS were calculated based on the records from the emergency department, and the BD was calculated based on the arterial blood gas analysis obtained within 30 minutes of admission. The efficiency of the three indicators as triage tools was evaluated by using cross tabulations in two - by - two matrices and by using a receiver operating characteristic (ROC) curve analysis. Results: When the mortality was used as the outcome parameter, the sensitivity and the accuracy of the initial BD were higher than those of the SIRS score (p<0.05) and were same as those of the t-RTS. The areas under the ROC curves of the initial BD, the SIRS score, and the t-RTS were $0.740{\pm}0.087$, $0.696{\pm}0.082$, and $0.871{\pm}0.072$, respectively (95% confidence interval). When emergency operation and blood transfusion requirements were used as outcome parameters, the comparisons of the sensitivities and the accuracies of the initial BD and the other two indicators showed the same pattern as mentioned above. The areas under the ROC curves of the initial BD were 0.7~0.8 and were larger than those of the SIRS score (p<0.05). Conclusion: The ability of the initial BD to predict injury severity and outcome was similar to those of the t-RTS and the SIRS score. Therefore, the authors suggest that the initial BD may be used as an alternative to previous triage tools for trauma patients.

Development of Well Placement Optimization Model using Artificial Neural Network and Simulated Annealing (인공신경망과 SA 알고리즘을 이용한 지능형 생산정 위치 최적화 전산 모델 개발)

  • Kwak, Tae-Sung;Jung, Ji-Hun;Han, Dong-Kwon;Kwon, Sun-Il
    • Journal of the Korean Institute of Gas
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    • v.19 no.1
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    • pp.28-37
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    • 2015
  • This study presents the development of a well placement optimization model, combining an artificial neural network, which enables high-speed calculation, with a simulated annealing algorithm. The conventional FDM simulator takes excessive time when used to perform a field scale reservoir simulation. In order to solve this problem, an artificial neural network was applied to the model to allow the simulation to be executed within a short time. Also by using the given result, the optimization method, SA algorithm, was implemented to automatically select the optimal location without taking any subjective experiences into consideration. By comparing the result of the developed model with the eclipse simulator, it was found that the prediction performance of the developed model has become favorable, and the speed of calculation performance has also been improved. Especially, the optimum value was estimated by performing a sensitivity analysis for the cooling rate and the initial temperature, which is the control parameter of SA algorithm. From this result, it was verified that the calculation performance has been improved, as well. Lastly, an optimization for the well placement was performed using the model, and it concluded the optimized place for the well by selecting regions with great productivity.

Stochastic response of suspension bridges for various spatial variability models

  • Adanur, Suleyman;Altunisik, Ahmet C.;Soyluk, Kurtulus;Dumanoglu, A. Aydin
    • Steel and Composite Structures
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    • v.22 no.5
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    • pp.1001-1018
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    • 2016
  • The purpose of this paper is to compare the structural responses obtained from the stochastic analysis of a suspension bridge subjected to uniform and partially correlated seismic ground motions, using different spatial correlation functions commonly used in the earthquake engineering. The spatial correlation function employed in this study consists of a term that characterizes the loss of coherency. To account for the spatial variability of ground motions, the widely used four loss of coherency models in the literature has been taken into account in this study. Because each of these models has its own characteristics, it is intended to determine the sensitivity of a suspension bridge due to these losses of coherency models which represent the spatial variability of ground motions. Bosporus Suspension Bridge connects Europe to Asia in Istanbul is selected as a numerical example. The bridge has steel towers that are flexible, inclined hangers and a steel box-deck of 1074 m main span, with side spans of 231 and 255 m on the European and Asian sides, respectively. For the ground motion the filtered white noise model is considered and applied in the vertical direction, the intensity parameter of this model is obtained by using the S16E component of Pacoima Dam record of 1971 San Fernando earthquake. An analytically simple model called as filtered white noise ground motion model is chosen to represent the earthquake ground motion. When compared with the uniform ground motion case, the results obtained from the spatial variability models with partial correlation outline the necessity to include the spatial variability of ground motions in the stochastic dynamic analysis of suspension bridges. It is observed that while the largest response values are obtained for the model proposed by Harichandran and Vanmarcke, the model proposed by Uscinski produces the smallest responses among the considered partially correlated ground motion models. The response values obtained from the uniform ground motion case are usually smaller than those of the responses obtained from the partially correlated ground motion cases. While the response values at the flexible parts of the bridge are totally dominated by the dynamic component, the pseudo-static component also has significant contributions for the response values at the rigid parts of the bridge. The results also show the consistency of the spatial variability models, which have different characteristics, considered in this study.

Economic Evaluation and Budget Impact Analysis of the Surveillance Program for Hepatocellular Carcinoma in Thai Chronic Hepatitis B Patients

  • Sangmala, Pannapa;Chaikledkaew, Usa;Tanwandee, Tawesak;Pongchareonsuk, Petcharat
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.8993-9004
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    • 2014
  • Background: The incidence rate and the treatment costs of hepatocellular carcinoma (HCC) are high, especially in Thailand. Previous studies indicated that early detection by a surveillance program could help by down-staging. This study aimed to compare the costs and health outcomes associated with the introduction of a HCC surveillance program with no program and to estimate the budget impact if the HCC surveillance program were implemented. Materials and Methods: A cost utility analysis using a decision tree and Markov models was used to compare costs and outcomes during the lifetime period based on a societal perspective between alternative HCC surveillance strategies with no program. Costs included direct medical, direct non-medical, and indirect costs. Health outcomes were measured as life years (LYs), and quality adjusted life years (QALYs). The results were presented in terms of the incremental cost-effectiveness ratio (ICER) in Thai THB per QALY gained. One-way and probabilistic sensitivity analyses were applied to investigate parameter uncertainties. Budget impact analysis (BIA) was performed based on the governmental perspective. Results: Semi-annual ultrasonography (US) and semi-annual ultrasonography plus alpha-fetoprotein (US plus AFP) as the first screening for HCC surveillance would be cost-effective options at the willingness to pay (WTP) threshold of 160,000 THB per QALY gained compared with no surveillance program (ICER=118,796 and ICER=123,451 THB/QALY), respectively. The semi-annual US plus AFP yielded more net monetary benefit, but caused a substantially higher budget (237 to 502 million THB) than semi-annual US (81 to 201 million THB) during the next ten fiscal years. Conclusions: Our results suggested that a semi-annual US program should be used as the first screening for HCC surveillance and included in the benefit package of Thai health insurance schemes for both chronic hepatitis B males and females aged between 40-50 years. In addition, policy makers considered the program could be feasible, but additional evidence is needed to support the whole prevention system before the implementation of a strategic plan.

Computation of Tides in the Northeast Asian Sea by Blending the Topex/Poseidon Altimeter Data (Topex/Poseidon 고도계 자료를 이용한 북동 아시아 해역의 조석 산정)

  • Kim, Chang-Shik;Matsumoto, Koji;Ooe, Masatsugu;Lee, Jong-Chan
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.6 no.1
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    • pp.1-12
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    • 2001
  • Tidal computations of $M_2,\;S_2,\; K_1$ and $O_1$ constituents in the northeast Asian sea are presented by blending the Topex/Poseidon (T/P) altimeter data into a hydrodynamic model with $5'{\times}5'$ resolution. A series of sensitivity experiments on a weighting factor, which is the control parameter in the blending method, are carried out using $M_2$ constituent. The weighting factor is set to be in inverse proportion to the square root of water depth to reduce noises which could occur in data-assimilative model by blending T/P data. Model results obtained by blending the T/P-derived $M_2,\;S_2,\; K_1$ and $O_1$ constituents simultaneously are compared with all T/P-track tidal data; Average values of amplitude and phase errors are close to zero. Standard deviations of amplitude and phase errors are approximately 2 cm and less than 10 degrees respectively. The data-assimilative model results show a quite good agreement with T/P-derived tidal data, particularly in shallow water region (h<250m). In deep water regions, T/P-derived tidal data show unreasonable spatial variations in amplitude and phase. The data-assimilative model results differ from T/P-derived data, but are improved to show reasonable spatial variations in amplitude and phase. In addition, the T/P-blended model results are in good agreement with coastal tide gauge data which are not blended into the model.

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Evaluation of DNA Double Strand Breaks in Human and Mouse Lymphocyte Following ${\gamma}-Irradiation$ (${\gamma}-Ray$ 조사에 따른 사람의 정상임파구와 마우스 정상임파구의 DNA Double Strand Break 발생율에 대한 비교분석)

  • Kim Tae Hwan;Kim Sung Ho;Chung In Yong;Cho Chul Koo;Ko Kyung Hwan;Yoo Seong Yul
    • Radiation Oncology Journal
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    • v.11 no.2
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    • pp.219-225
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    • 1993
  • The evaluation of radiation-induced DNA double strand breaks (DSB) was made following irradiation of human lymphocytes, murine lymphocytes and EL-4 leukemia cells over a wide dose range of $^{60}Co\;{gamma}-rays.$ In lipopolysaccharide (LPS) or phytohemagglutinin (PHA)-stimulated murine lymphocytes, the slopes of the stand scission factor (SSF) revealed that lymphocytes with LPS increased DNA DSB formation by a factor of 1.432 (p<0.005). Furthermore, strand break production was relatively inefficient in the T lymphocytes compared to the B lymuhocytes. And EL-4 leukemia cells were found to form significantly more DNA DSB to a greater extent than normal lymphocytes (p<0.005). The in vitro studies of the intrinsic radiosensitivity between human lymphocytes and murine lymphocytes showed similar phasic kinetics. However, murine lymphocytes were lower in DNA DSB formation and higher in the relative radiation dose of 10 percent DNA strand breaks at 3.5 hours following ${gamma}-irradiation$ than human lymphocytes. Though it is difficult to interpret these results, these differences may be result from environmental and genetic factors. From our data, if complementary explanations for this difference will be proposed, the differences in the dose-effect relationship for the induction of DSB between humans and mice must be related to interspecies variations in the physiological condition of the peripheral blood in vitro and not to differences in the intrinsic radiation sensitivity of the lymphocytes. These results can be estimated on the basis of dose-effect correlation enabling the interpretation of clinical response and the radiobiological parameters of cytometrical assessment.

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