• YAKHAK HOEJI
• /
• v.55 no.1
• /
• pp.1-10
• /
• 2011

Mastic is a bleed resin formed in pistacia lentiscus tree extract form the anacatdiaceae family. Mastic is used as a food ingredient in the Mediteraanean resin, and has been used by local inhabitants as a traditional medicine for relief of upper abdominal discomfort, dyspepsiaand peptic ulcer. Clinically, mastic has been effective in the treatment of benign gastric and duodenal, ulcers, giving symptomatic relief and endoscopically proven healing. In this study, to enhance activiteies of poorly water soluble Mastic with oils, surfactants and cosurfactants and then the mixure was microemulsified in aqueous media under condition of gentle agitation and digestive motility that would be encountered in the gastrointestinal tract. Formulation development and screening were based on phase diagrams and characteristics of resultant microemulsion. For optimum mastic formulation, microemulsions with various ratio (w/w%) of mastics, oils, surfactants and cosurfactants were prepared and their solubility was evaluated by monitoring particles size in their buffer through visual asessment and electrophoretic light scattering spectrophotomerter (ELS). In vitro activity of self microemulsified mastic (SME mastic) was determined by minimum ingibition concentration (MIC) test against a panel of Helicobacter pylori (H. pylori) clinical strains. Additionally, in vivo activity of SME masitc was investigated us mouse infected by CH275 of H. pylori. The mean diameter of SME mastic was less then 100 nm in water and SME mastic was showed similar antiboisis effect compared to tometronidazole, clarithromycin and omeproazole. Consequently, SME mastic would be effective system to exterminate H. pylori. If mastic were dose with combined treatment, mastic might augur well for effect of H. pylori eradication as good remedy.

• Journal of the Computational Structural Engineering Institute of Korea
• /
• v.13 no.2
• /
• pp.189-196
• /
• 2000

The objective of this paper is to propose an analysis technique to predict the behavior of PC wall structures subjected to cyclic load. While PC wall panel is idealized by finite elements, the joints at which PC walls are connected each other are idealized by nonlinear spring elements. Axial and shear spring elements are developed for simulating shear, compression and tension behaviors of joints. The strength and stiffness of each spring elements we presented from the previous research results and incorporated into the computer program of DRAIN-2DX. The proposed analysis technique is evaluated by analyzing specimens previously tested and comparing with those. On the strength, stiffness, energy dissipation and lateral drift, analytical results show good agreements with test results. This means the proposed technique is effective to predict the response of the PC wall structures.

• Food Science of Animal Resources
• /
• v.26 no.3
• /
• pp.284-289
• /
• 2006

Effects of feeding timothy hay roughage in the growing period on the beef quality with during 24 month(5 month from 28 month to) in twenty Hanwoo steers were investigated. Hanwoo steers were randomly assigned to 2 groups (10 heads/treatment), the control group (C) and the treatment group (T). Cooking loss and the shear force value of m. longissimus tended to be higher in the control group, and the panel test scores of juiciness and flavor were higher in the treatment group. However the tenderness was significantly higher in the treatment group (5.10 points) relative to the control group (4.30 points) (p<0.05). The proportion of fatty acids that were saturated ranged from $42.83{\sim}40.75%$. The unsaturated fatty acid, mono-unsaturated fatty acid and poly-unsaturated fatty acid contents in the two groups were not significantly different (59.25%, 55.61% and 3.40%, respectively, for T; 57.17%, 54.40% and 2.77%, respectively, for C) (p>0.05).

• Environmental and Resource Economics Review
• /
• v.12 no.3
• /
• pp.515-529
• /
• 2003

This theoretical model makes three contributions to the study on economic growth and environment. First, emissions are generated during final goods production and technology accumulation. Second, this paper assumes that pollution is directly increasing with increase in final goods output or in consumption. Third, we use reproducible factors associated with labor and capital input in production function and assume constant return to scale in reproducible factors. From growth rate condition we derived, increases in reproducible factors, increases in productivity of either the abatment or technology sector, and decrease in social discount rate would increase the sustainable growth rate. In empirical test, the environmental degradation did not effect the economic growth rate though other factors satisfied the growth rate condition equation. However, through the reinterpretation of this result, we found indirectly the fact of that an inverted U relationship between air pollution and economic growth rate would exist in 20 OECD countries using a panel data for the period of 1986~1995.

• Journal of Korean Society of Environmental Engineers
• /
• v.39 no.1
• /
• pp.19-25
• /
• 2017

In this study, a electrostatic filter which could be applicable to road environment was developed and evaluated in adsorption capacity. The evaluation were performance for removal by particle size and adsorption amount by pressure using ASERAE 52.1 and 52.2. The range of size for removal test was $0.3{\mu}m{\sim}10.0{\mu}m$ which had 12 steps. The filter showed 91.3% removal efficiency from $2.5{\mu}m$ and under the size, average 53.5% proportional to decreasing size value. The weight removal was 96.7% from 22.6 mmaq, initial pressure to 35 mmaq, end pressure with $715.9g/m^2$, the adsorption amount. The shape of isotherm was expressed as Langmuir's one. After washing saturated filter with dust to end pressure, the initial pressure and adsorption amount of the filter showed a light drop with no removal efficiency decline.

• Korean Journal of Food Science and Technology
• /
• v.4 no.3
• /
• pp.194-199
• /
• 1972

To investigate the feasibility of producing yoguhrt from soybean milk which will be acceptable for Korean this experiment was carried out. The addition of pasteurized milk into soybean milk speeded up acid production by L. casei and also demonstrated the improvement of acceptability of the product. Certain additives like glucose, lactose and yeast extract also stimulated acid production. It was found that the yoguhrt of pH range of $4.2{\sim}3.7$ was well agreed to Korean preference. It was also observed by panel test in this study that the acceptability of Korean for yoguhrt increased through repeated tasting, and in consequence, this would turn out to be an ordinary acceptable food item, even though it is felt quite objectionable at the beginning of taste.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.11 no.4
• /
• pp.1-6
• /
• 1982

This study designed to elucidate free amino acid composition and calcium, iron contents in extractive cooking. broth of boiled-dried anchovy. Composition of the free amino acid in boiled-dried anchovy, in large and medium one appeared the same tendency. Abundant free amino acid of boiled-dried anchovy were histidine, alanine, lysine, leucine, glycine and glutamic acid in order. The total free amino acid was greatly extracted from cooking broth when boiled at 30 minutes. Free amino acid, such as histidine, alanine, lysine, leucine and glutamic acid had abundant in cooking broth. The calcium and iron contents in broth were little difference between large and medium one. Calcium and iron contents were highest in cooking broth when boiled at 30 minutes. Panel test on general accetability was very good in the boiling at 30 minutes.

• Genomics & Informatics
• /
• v.7 no.1
• /
• pp.20-25
• /
• 2009

Rheumatoid arthritis (RA) is a chronic autoimmune disorder that is characterized by inflammation of the synovial tissue and deterioration of the joint and bone. A recent study reported a potential gene-environment interaction between HLA-DR and smoking. The present study investigated whether a specific gene was related to the association between smoking and the severity of RA (rheumatoid factor levels > 20 IU/ml). We used the resources of the NARAC family collection of GAW 15 databases, and 1139 subjects with RF>20 IU/ml were included in the current analysis. The linkage panel contained 5858 SNP markers, and 5744 SNPs passed quality control criteria. Linear regression analyses, using PLINK software and generalized estimating equation regression models, were used to test for associations between the SNPs and the severity of RA according to smoking groups. Two major findings were established. First, the severity of RA in smokers was associated with rs703618 (p=$6{\times}10^{-5}$), which lies in the intronic region of the stabilin 2 (STAB2) gene on chromosome 12. Second, there were significant differences in the levels of RF between 'ever smokers' and 'never smokers' according to the rs703618 genotype (G/G, A/G, A/A). We investigated whether a specific gene acts as a mediator between smoking and the severity of RA and found that the STAB2 gene could affect this relationship. Our finding indicates that smoking may mediate RA severity by affecting the expression level of a specific gene.

• Biomedical Science Letters
• /
• v.24 no.3
• /
• pp.245-252
• /
• 2018

Heart rate recovery (HRR) is simply an indicator of autonomic balance and is a useful physiological indicator to predict cardiovascular morbidity and mortality. The purpose of this study was to compare the differences in HRR between metabolically healthy obesity group and metabolically unhealthy obesity and to ascertain whether heart rate recovery is a predictor of metabolic syndrome. Metabolic syndrome was defined according to the standards of the National Cholesterol Education Program Adult Care Panel III. Obesity was assessed according to WHO Asian criteria. It was classified into three groups of metabolically healthy non-obesity group (MHNO, n=113), metabolically healthy obesity group (MHO, n=66), metabolically unhealthy obesity (MUO, n=18). Exercise test was performed with Bruce protocol using a treadmill instrument. There was no difference in HRR between MHO and MUO ($32.71{\pm}12.25$ vs $25.53{\pm}8.13$), but there was late HRR in MUO than MHNO ($25.53{\pm}8.13$ vs $34.51{\pm}11.80$). HRR in obese was significantly correlated with BMI (r=-0.342, P=0.004), waist circumference (r=-0.246, P=0.043), triglyceride (r=-0.350, P=0.003), HbA1c (r=-0.315, P=0.009), insulin (r=-0.290, P=0.017) and uric acid (r=-0.303, P=0.012). HRR showed a lower prevalence of abdominal obesity, hypertriglyceridemia, and low HDL-cholesterol in the third tertile than in the first tertile. In conclusion, MHO had no difference in vagal activity compared with MHNO, but MUO had low vagal activity. HRR is associated with metabolic parameters and is a useful predictor of abdominal obesity, hypertriglyceridemia, and low HDL-cholesterolemia.

• Journal of Korean Tunnelling and Underground Space Association
• /
• v.13 no.2
• /
• pp.149-158
• /
• 2011

Utilization of the fiber reinforced polymer (FRP) material has been increased as an alternative in a bid to supplement the problems with general construction materials such as long-term problems corrosion, etc. However, there are still many problems in using a linear-shaped FRP material for a tunnel lining structure which has arch-shape in general. In this study, the loading tests for the FRP-concrete composite member was carried out to evaluate their applicability as a tunnel reinforcement material, which are based on the results from preliminary numerical studies for identifying the behavioral characteristics of FRP-concrete composite member. Moreover, numerical analysis under the same condition as applied in the loading tests was again conducted for analysis of mechanical behavior of the composite member. As a result of the load test and numerical analysis, it appears that the FRP-concrete composite member is greatly subject to shear movement caused by bending tension acting on the interface between two constituent members.