• Journal of the Korean Society of Industry Convergence
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• v.10 no.4
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• pp.263-269
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• 2007

A numerical algorithm for three-dimension laminar flow in an agitated vessel was established by using the spherical coordinates. Flow pattern for the double-stage paddle impeller was not dependent upon the distance of among the impeller in the agitated vessels. The numerical simulation of the flow pattern in spherical and cylindrical agitated vessel agree well with the visualization results.

• Journal of the Korean Society of Industry Convergence
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• v.9 no.4
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• pp.247-253
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• 2006

Power consumption for double-stage paddle impeller in spherical and cylindrical agitated vessel was measured over a wide range of Reynolds number from laminar to turbulent flow regions. The power correlation was obtained which was applied to both spherical and cylindrical vessel, when the apparent diameter of the spherical vessel was equal to the diameter of the cylindrical vessel which had a height equal to its diameter and had the same volume as the spherical vessel. The power consumption for the double-stage impeller was dependent upon the distance of among the impeller in the agitated vessels, as follows: $$f/2={\frac{C_L}{Re_G}}+{\frac{Ct}{2}}({\frac{C_tr}{Re_g}}+Re_g)^{-m}$$

• 한국전산유체공학회:학술대회논문집
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• 2000.10a
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• pp.109-114
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• 2000

Mechanical agitation is widely used in industrial process engineering. In the present study, peformed was a numerical simulation on flows in a $45^{\circ}$ Pitched Paddle Type mixer. Through a CFD technique, effects of the position of the impeller on resultant flow pattern was studied. Results of computed torque on impeller to maintain the flow are also compared to the experimental data, and showed good qualitative agreements.

• Applied Chemistry for Engineering
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• v.16 no.5
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• pp.698-704
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• 2005

Power consumption for paddle impeller in spherical and cylindrical agitated vessel was measured over a wide range of Reynolds number from laminar to turbulent flow regions. The power correlation was obtained for both spherical and cylindrical vessels, where the apparent diameter of the spherical vessel was equal to the diameter of the cylindrical vessel (height equal to its diameter and had the same volume as the spherical vessel). The power consumption well correlated with the experimental results of Nagata, et al. and Hixson-Baum. Also the critical Reynolds numbers was directly related to the transition coefficient $C_{tr}$ characterizing the transition from a laminar to a turbulent flow region in the correlation proposed here.

• Applied Chemistry for Engineering
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• v.17 no.5
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• pp.509-516
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• 2006

The solid-liquid mass transfer coefficients $k_L$ in a gas-liquid-solid three phases agitated vessel were measured with conventional impellers (e.g. Rushton turbine, paddle, and propeller). For the conventional impellers the rotational speed for the complete suspension $N_{js}$ changes with the impeller height and gas flow rate. Mass transfer coefficient of the Rushton turbin impeller, for which the particle suspension was independent of the aeration, is correlated only with Pgv. Mass transfer coefficients $k_L$ for the Rushton turbine, paddle and propeller impellers were affected by the impeller position.

• Journal of the Korean Society of Industry Convergence
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• v.11 no.1
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• pp.19-26
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• 2008

The gas-liquid mass transfer volumetric coefficients in gas-liquid agitated vessels with wire gauge impellers were measured to be compared with those in vessels with disk turbine and paddle impellers. Also mass transfer volumetric coefficients for disk turbine, paddle impeller and wire gauge impeller in cylindrical agitated vessel was measured over a wide range of Reynolds number from turbulent flow to transition regions. The effect of geometries on $k_La$ is clarified experimentally. Mass transfer volumetric coefficients $k_La$ depends only on the power consumption ($P_{gv}+P_{av}$) per unit volume.

• 한국전산유체공학회:학술대회논문집
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• 2005.10a
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• pp.55-59
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• 2005

CFD analysis has been conducted to find the two stage impeller configuration which is the most suitable for a stirred tank with an internal helical cooling coil and a cooling jacket, which is frequently used in chemical industries for highly exothermic reactions ranged from low to medium viscosity. Two typical types of impellers are considered; pitched paddle impellers and Rushton turbine impellers. Interestingly, pitched paddle impellers show a good mixing performance for multi-species, whereas Rushton turbine impellers achieve a good mixing performance for multi-phases. Besides the type of an impeller, the location of an impeller is another important factor to be considered in order to accomplish an effective mixing. The best set of types and locations of two impellers is recommended based on the coefficient of variation(CoV) value and the heat removal capability obtained from CFD results. The former is a measure to quantify the degree of mixing.

• KSBB Journal
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• v.4 no.3
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• pp.221-228
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• 1989

Celluose is an insoluble substrate, therefore, a proper mixing of the cellulose suspension is essential for an effective enzymatic hydrolysis. To study the effect of mixing motion of various enzyme reactors on enzymatic hydrolysis of cellulose, three distinct types of biroreator: vertical impeller type bioreator(VITB), horizontal paddle type bioreactor(HPTB), and tumbling drum type bioreactor(TDTB), were assembled and their performance was compared. The optimal agitation speed was 100rpm for VITB and HPTB, 200rpm for TDTB. The saccharification efficiency of each reactor was compared under the optimal agitation intensity. The highest degree of saccharification was achieved in the case of VITB, especially, at high cellulose concentration. The VITB seems to be the most suitable type of bioreactor that can maintain proper mixing pattern for effective enzyme reaction. In the view of energy consumption, the TDTB showed the lowest value: however, the energy consumption was rapidly increased at high concentration of celluose. To dertermine the most suitable type of bioreactor, the entire process, including substrate cost, substrate concentration, and feasibility of scale-up, needs to be evaluated.

• KSBB Journal
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• v.6 no.3
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• pp.231-240
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• 1991

Recently, developments of large scale and high density cell culture methods have been the objects of many researches, because the demand of various pharmaceutical products produced by animal cell culture has been rapidly increasing. The cell culture equipment should have the requirements such as sufficient oxygen transfer and mixing, low shear stress and surface tension, and small foaming. In order to develop a proper bioreactor meeting these requirements simultaneously, a perfluorocarbon having high solubility of oxygen was sprayed into the medium as an oxygen carrier instead of air. Also, a new impeller was developed and combined together with the perfluorocarbon spraying system so as to design a new bioreartor for cell cultivation. The new impeller had better characteristics of mixing and oxygen transfer than the paddle and cell-lift impellers based on the same, shear rate. But, it was observed that the volumetric oxygen transfer coefficient of the new bioreactor decreased with increasing cell density during E. coli fermentation.

• KSBB Journal
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• v.14 no.5
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• pp.534-538
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• 1999

For the optimization of operating conditions for plant cell suspension culture in bioreactors, effects of bioreactor types, various kinds of impellers, and aeration rates were examined using Nicotiana tabacum cells as a model system. Stirred tank bioreactor and airlift bioreactor were used for the comparison of bioreactor type. Growth rates in both bioreactors were lower than in shake flasks. In terms of final cell concentration, stirred tank bioreactor supported a little bit better growth compared to airlift bioreactor. Impeller type did not affect cell growth significantly, but it was apparent that cell size index decreased in the case of using hollowed paddle impeller. When the aeration rate was maintained at 0.3 vvm, cell growth was the best. At above 1.0 vvm, growth inhibition as well a browning was noticed. In addition, it was found that cell size index reduced proportionally to the increased of aeration rate.