• Title/Summary/Keyword: pH 영향

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A 4 week Randomized, Double-blind Human Trial to Compare the Efficacy and Safety of Aureobasidium pullulans Cultured Solution and Placebo on Improvement of Immune in Subjects (흑효모배양액 분말의 면역관련 사이토카인에 미치는 영향에 대한 무작위 배정 임상연구)

  • Choi, Hae-Yun;Kim, Jong-Dae;Park, Mee-Yeon
    • Korean Journal of Oriental Medicine
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    • v.15 no.3
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    • pp.83-91
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    • 2009
  • $\beta$-glucan is a fiber-type complex sugar (polysaccharide) derived from the cell wall of baker's yeast, oat and barley fiber, and many medicinal mushrooms, such as maitake. The primary uses of $\beta$-glucan are to enhance the immune system, to lower blood cholesterol levels and to treat tumor. $\beta$-glucan has no systemic toxicity in mice, therefore it needed clinical trail to prove efficacy and safety for human. The subjects total 56 healty volunteers were divided into two groups including taken $\beta$-glucan tablet group and placebo group. Subjects were taken two tablets per oral for 4 weeks. They had agreed to take part in this experiment, and didn't take any other clinical trail products. After 4 weeks blood of subjects were checked. The check list are TNF-$\alpha$, INF-$\gamma$, IL-2, IL-4, total WBC, differential WBC, RBC, hemoglobin, platelet, MCV, MCH, MCHC, HCT, Na, K, Ca, Cl, AST, ALT, ALP, $\gamma$-GTP, total protein, triglyceride, total cholesterol, total bilirubin, albumin, uric acid, creatinine, BUN, pH, protein, glucose, ketone body, blood, bilirubin. We evaluated efficacy by cytokines that compare before and after taking. Collected data were analyzed as two sample t-test, chi-square test and ANOVA using SAS V.9.1.This study results are that in TNF-$\alpha$ of $1^{st}$ efficacy measurement item, all of two groups figure were increased significantly compare to before figure. In IL4 of $2^{nd}$ efficacy measurement item, experimental group figure were decreased significantly but placebo group figure were increased. The conclusions show that based on the above results, $\beta$-glucan has favorable effect to enhance immune system, especially IL4 results showed that it has effect to improve the allergic immune system.

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Apparent Densification Rate and Initial Permeability of NiCuZn Ferrite Depended on Relative Packing Density (NiCuZn Ferrite의 겉보기 고화속도와 초기투자율의 충진율 의존성에 관한 연구)

  • 류병환;이정민;고재천
    • Resources Recycling
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    • v.7 no.4
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    • pp.27-34
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    • 1998
  • In this research, the processing control of NiCuZn Ferrite (NCZF) had been studied. NiCuZn Ferrite, which calcined at $700^{\circ}C$ for 3 bours, was ball milled for about 60 hours to ill김ke a size of $0.5\mu\;extrm{m}$ followed by granulation using spray dryer Apparent densincatioo rate and initial permeability of NiCuZn Ferrite with an initial packing density had been investigated as f follows. 1.The relative packing density of NCZF green body increas$\xi$d in the range of 48.6-56.8% with an increased forming pressure of 20-170 MPa. 2. The higher the relative pac퍼ng density of NCZF and the sintering temperature are, the higher the initial densification rate. The increased bulk rlcnsity of NCZF was attributed to the densification rate with decreased open pore and increased closed pore as the relative packing density, sintering temperature, and sinteriog tim$\xi$ increased. 3. The initial P permeability of NCZF with constant composition is logarithmically proportional to the bulk density of NCZF sintered at $875~925^{\circ}C$ for 0-5h, and strongly depended on the relative packing density of NCZF green body. The empirical equation is as f follows; log $\mu$i=$G1{\times}BD$+$G2{\times}RPD$+b(0);where, G1, G2; gradient, B.D: bulk density, RPD; relative packing density, b(0); intercept.

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Application in Conductive Filler by Low-Temperature Densification and Synthesis of Core-Shell Structure Powder for Prevention from Copper Oxidation (구리 산화 방지를 위한 Core-Shell 구조 입자 합성과 저온 치밀화를 통한 도전성 필러 응용)

  • Shim, Young Ho;Park, Seong-Dae;Kim, Hee Taik
    • Applied Chemistry for Engineering
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    • v.23 no.6
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    • pp.554-560
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    • 2012
  • Recently, it has been increasing trend to use conductive materials as electronics and communication technology in electronics industry are developing. The noble metal such as Ag, Pt, Pd etc. are mostly used as conductive materials, To reduce production cost, alternative materials with similar characteristics of noble metals are needed. Copper has advantages, i.e its electronic properties are similar to noble metals and low cost than noble metal, but its use has been restricted because of oxidation in air. In this study, the tin film was coated on copper by electroless plating to protect copper from oxidation and to confirm the effects of temperature, pH, amount of $SnCl_2$, and feeding speed in plating conditions. Additionally, we apply $Cu_{core}Sn_{shell}$ powder as conductive filler with low-temperature densification and analysis by SEM, XRD, FIB and 4-Point Probe techniques. As result of the study, tin film was coated well on copper and was protected from oxidation. After low-temperature densification treatment, the meted tin made chemical interconnections with copper. Accordingly, conductivity was increased than before condition. We hope $Cu_{core}Sn_{shell}$ powder to replace noble metals and use in the electronic field.

Physicochemical properties of rice-distilled spirit matured in oak and stainless steel containers (숙성용기를 달리한 전통 쌀 증류식 소주의 숙성 중 이화학 특성 및 향기성분의 변화)

  • Kang, Sun-Hee;Kim, Jae-Ho;Lee, Ae-Ran;Kim, A-Ra;Kim, Tae-Wan
    • Korean Journal of Food Science and Technology
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    • v.49 no.4
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    • pp.369-376
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    • 2017
  • Maturation of distilled spirit can generate diverse flavors and tastes. Rice Soju was matured in oak casks (MSO) and stainless steel containers (MSS) for one year at ambient temperature. Ipguk (Aspergillus luchuensis) and Saccharomyces cerevisiae Y88-4 were used, and reduced pressure ($110{\pm}20Torr$) distillation was applied to brew Soju. Acidity and conductivity were increased in both MSO and MSS. MSO reduced alcohol content (from 43 to 40%) and volume (from 18,000 to 12,730 mL), and significantly altered yellowness (from 0.2 to 30.2). Furthermore, MSO increased the isoamyl alcohol (from 276.7 to $339.2{\mu}g/mL$) and isobutyl alcohol (from 122.3 to $144.2{\mu}g/mL$) content. Gas chromatography-mass spectrometry was used to detect volatile compounds in Soju, which included 20 esters, 7 alcohols, 2 acids, and 5 miscellaneous compounds. Oak lactone was detected only in MSO and was considered as a specific flavor component associated with oak maturation. Thus, maturation materials contribute to the physicochemical property of distilled spirits.

The Effect of Concentrated Onion Juice in a Body Composition, Serum Electrolytes and Lipids Levels on Hyperlipidemia (양파 농축액이 고지혈증 성인 남자의 체성분, 혈장 전해질 및 지질 성분에 미치는 영향)

  • 황금희;정난희;조남철;유영균;박평심;노영희;서희숙;노인옥
    • The Korean Journal of Food And Nutrition
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    • v.16 no.1
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    • pp.36-45
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    • 2003
  • It is known as that onion is antioxidation effect, antibiotic effect, blood pressure decreasing effect and reducing serum cholesterol levels. This research about effect that onion concentrate gets blood cholesterol levels and body composition. Subject was 17 adult men of hyperlipidemia. Age distribution of investigation subjects were average 49.4 years old by 40~56 years old, and average height and weight were 167.6cm and 75.5kg each, BMI was 26.9kg/$m^2$, and BMR was 1,460.6$\pm$87.5㎉, and AMC was 25.0$\pm$1.05cm, and BCM was 41.0$\pm$2.79cm. In the meantime, the body muscle was 53.7$\pm$3.7kg, and fat mass was 18.7$\pm$3.8kg, and intracellular fluid was 26.6$\pm$1.8kg, and extracellular fluid was 12.8$\pm$0.9kg. The % body fat was 24.6$\pm$3.8%, and fat distribution was 0.9$\pm$0.0%, and the obesity degree was 125.4$\pm$8.2%. Vegetables, seaweeds, fruits and juices increased by change of dietary life and greasy foods, instants, breads, rices etc. decreased or there was no change, fast foods and eggs were no change. Also, subject previewed that guidance about stress, smoking, drinking and beverage intake need. If compared the nutrient intake amount with before onion concentrate allowance, it was similar level almost without significant. Energy, calcium and riboflavin are lower than the RDA for koreans. After 3 months, the levels of plasma total cholesterol, triglycerides had decreased significantly : 15.0%, 31.2% respectively. And the HDL-cholesterol and LDL-cholesterol levels also showed a marked reduction of 6.8%, 8.7% respectively. Plasma lipid level change by onion concentrate supplement would can know that case of triglyceride more greatly than plasma cholesterol. The pH and Na+ level of plasma were low significant since 8 weeks after, and $K^{+}$ level increase significant. While $Ca^{++}$ level was low significant after 1 month, there was no change since 2 months after, but nC $a^{++}$ level was low significantly. Plasma $Mg^{++}$ level was no change and nM $g^{++}$ level was low significant after intake.e.e.e.e.e.

Characteristics of bitter peptides from Doenjang (된장의 쓴맛 펩타이드 특성)

  • 홍혜정;이혜수
    • Korean journal of food and cookery science
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    • v.10 no.1
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    • pp.45-50
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    • 1994
  • Conventional Doenjang, three kinds of Improved Doenjang(A; koji: soybean: salt=53: 100: 33, B; koji: soybean: salt=100: 100: 40, C; koji: soybean: salt= 200: 100: 40) prepared with different ratio of koji and salt were made to study the changes in the general contents, characteristics bitter peptides, correlations between bitterness and overall eating quality. 1. Total nitrogen contents increased a little, and amino nitrogen contents in all samples increase markedly. Especially, Amino nitrogen contents of conventrional Doenjang increased more than others. Reducing sugars of doenjang prepared with Asp. oryzae were higher than conventional Doenjang and increased throughout the aging period and Doenjang prepared with Asp. oryzae were more acidic. 2. To characterize bitter peptides in fermented Doenjang, peptides were extracted with 2: 1(v/v) chloroform-methanol and separated by Gel chromato-graphy with Sephadex and TLC. After Gel chromatography and TLC, each fraction examined presence of bitterness and evaluated intensity of bitterness. Amino acid composition of the fractions showing bitter tastes were as follows. Conv. peak 1-1 Trp-(Asp, Arg, Thr, Ser, Glu, Pro)-Phe Imp. A peak 1 Trp-(Glu, Val, Arg, lie)-Phe Imp. B peak 1 Trp-(lie, Pro, Asp, Lys, Val, Glu)-Trp. Imp. C peak 1-2 Trp-(Try, Thr, Glu, Pro, Gly)-Phe 3. Sensory evaluation revealed that correlation coefficient between bitterness and overall eating guality was not high.

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Removal Efficiency of Cochiodinium polykrikoides by Yellow Loess (황토의 유해성 적조생물 Cochiodinium종의 제거효과)

  • CHOI Hee Gu;KIM Pyoung Soong;LEE Won Chan;YUN Seong Jong;KIM Hak Gyoon;LEE Hung Jae
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.31 no.1
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    • pp.109-113
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    • 1998
  • The clay and yellow loess have capability to adsorb and precipitate particles. The removal efficiencyes of those flocculents on the dinoflagellate, Cochlodinium polykrikoides, have been studied in laboratory and in field near Tongyong fish farm in September, 1996. The removal efficiencyes in the laboratory experiment was $43\%$ for $2\;g/{\ell}$, $64\%$ for $6g/{\ell}$ and $88\%$ for $10\;g/{\ell}$ in one hour after dispersion. No big difference of removal efficiency was found between the raw and the acid-activated loess. In the field survey, the removal rates ranged from 72 to $80\%$ in 30 min after the dispersion. The effect of loess scattering on water quality was estimated. The concentrations of dissolved inorganic nitrogen (DIN), chemical of gen demand (COD) and chlorophyll a decreased more or less after dispersion, while the concentration of suspended solid (SS) increased. The concentrations of dissolved oxygen (DO) and dissolved inorganic phosphorous (DIP) were kept constant. These results indicated that the dispersion concentration of more than $10g/{\ell}$ has a good removal efficiency of above $80\%$ without big variation of water quality after dispersion of yellow loess.

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Antioxidant and Inhibition of Nitrosodimethylamine Formation in Marketing Black Garlics (시판 흑마늘의 항산화 및 Nitrosodimethylamine의 생성억제)

  • Cha, Ji-Young;Lee, Soo-Jung;Shin, Jung-Hye;Sung, Nak-Ju
    • Journal of agriculture & life science
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    • v.46 no.2
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    • pp.151-162
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    • 2012
  • Four kinds of marketing black garlics (A, B, C and D products) from Namhae were analysed the antioxidant, nitrite scavenging activities and inhibition of nitrosodimethylamine (NDMA) formation. Total pyruvate and thiosulfate contents were higher in the black garlics than fresh garlic, and their contents were the highest in B product. Total phenol and flavonoids contents in the water and 80% ethanol extracts from black garlics were higher in water than ethanol extract, and all black garlics were higher than fresh garlic. And these contents of A product were somewhat higher compared to the others. Antioxidant activities, such as DPPH, ABTs, hydroxyl and nitric oxide radical scavenging showed stronger in water than ethanol extracts. And their activities in all products of black garlic were higher than the extracts of fresh garlic, and their activities of A and B products were similar to each other. In pH 2.5, nitrite scavenging activity and inhibition of NDMA formation were stronger in the black garlics than fresh garlic, and A product was the highest. Moreover, inhibition of NDMA formation from black garlic showed similar trends compared to the antioxidant activities. Therefore, we expect that the black garlic will contribute to the inhibition of carcinogenesis in vivo.

Effects of Stock Plant Management and Foliar Spray of GA on the Flower Quality in Hydroponically Grown Chrysanthemum cv. 'Shinma' (모수포 관리 및 지베렐린 처리가 국화 '신마'의 절화품질에 미치는 영향)

  • Hwang, In Taek;Cho, Kyung Chul;Kim, Hee Gon;Ki, Gwang Yeon;Yoon, Bong Ki;Kim, Jung Guen;Han, Tae Ho;Lee, Jeong Hyun;Yoo, Yong Kweon
    • FLOWER RESEARCH JOURNAL
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    • v.18 no.4
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    • pp.256-260
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    • 2010
  • This study was carried out to investigate effects of stock plant management and foliar spray of GA on the flower quality in hydroponically grown chrysanthemum 'Shinma'. In the growth and development as affected by stock plant management, cut flower length, petal number and cut flower weight were the best in the plot of long day and chilling treatment showed 114 cm, 298 and 102 g, respectively. Chlorophyll content(SPAD-value) was the highest in the plot of foliar spray of diluted Molbia(1 : 500). Flower quality according to concentration and spray time of gibberellin showed a different pattern. Cut flower length was the longest in the plot of solution diluted to 1 : 1,000 spraying before flowering at 60 days, petal number was the most in 1 : 500 at 60 days, and cut flower weight was the heaviest in 1 : 2,000 at 60 days, respectively. However, peduncle length was tended to be elongated with foliar spray of gibberellin solution diluted to 1 : 500 or 1 : 1,000 before flowering at 45 days.

Comparison of Growth Characteristics of Aster scaber in Plastic House by Treatment of Soil Conditioners (참취 시설재배지 토양개량제 처리에 따른 생육특성 비교)

  • Yeom, Gue-Saeng;Moon, Jung-Seob;Yang, Jin-Ho;Kim, Dong-Won;An, Min Sil
    • Proceedings of the Plant Resources Society of Korea Conference
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    • 2019.10a
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    • pp.51-51
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    • 2019
  • 참취(Aster scaber)는 국화과에 속하는 여러해살이식물로 취나물로 분류되어 전국에서 재배되고 있으며 주로 남부지역에서 조기재배 작형으로 많이 재배하고 있다. 참취의 잎과 줄기는 맛과 향기가 독특하여 예로부터 생채, 묵나물 등으로 이용되어 왔으며 칼슘, 철분, 비타민 A 등이 풍부하여 건강식품으로서도 가치가 높고 한약재로도 사용되기도 한다. 최근에는 항암효과와 더불어 콜레스트롤을 저하시키는 약리적 효능이 있는 것으로 밝혀져 기능성 식품으로도 각광 받고 있다. 참취 시설재배 시 통상 3년 마다 갱신이 이루어지고 있는데 그 이유로는 시설재배지 특성상 양분의 과다투입에 의한 염류집적과 잦은 관수로 물리성이 악화되어 참취의 생육이 저하되어 수량이 감소하는 결과를 초래한다. 본 연구는 토양개량제 처리에 따른 참취의 생육과 토양 물리화학성에 미치는 영향을 검토하여 참취 시설재배 농가에 활용할 수 있는 방안을 개발하고자 시험을 수행하였다. 2018년 4월부터 2019년 9월까지 전라북도 농업기술원 허브산채시험장에서 참취 시설재배를 대상으로 하고 무처리, 볏짚 1,000 kg/10 a, 왕겨 숯 1,000 kg/10 a, 야자섬유 1,000 kg/10 a, 4처리구로 하여 시기별 생육 및 토양특성을 조사하였다. 수확기 참취 생육특성은 초장은 25.6~27.2 cm, 엽장은 8.5~9.7 cm, 엽폭은 6.3~7.0 cm, 경직경은 4.3~4.6 cm, 및 수량은 $3.3{\sim}4.0kg/3.3m^2$으로 볏짚 처리구에서 대조구에 비해 좋은 생육 상황을 보였으며 수량성 또한 많았다. 시험 후 토양화학적 특성을 조사한 결과 토양 pH는 7.4~7.5, 토양유기물 함량은 34~36 g/kg, 유효인산 함량은 386~415 mg/kg 이었으며 처리 전 토양에 비하여 유기물 함량은 증가하고 유효인산은 낮아지는 경향을 보였다. 치환성 양이온 K, Ca, Mg는 K는 $0.8{\sim}1.0cmol_c/kg$로 낮아졌고, Ca와 $8.9{\sim}10.1cmol_c/kg$, Mg는 $3.1{\sim}3.4cmol_c/kg$로 증가하였다. 토양물리성의 변화는 왕겨숯 시용에서 대조구에 비해 가장 낮은 용적밀도 $1.22g/cm^3$와 가장 높은 공극률 54.09%을 보였다. 토양 삼상은 고상은 볏짚에서 51.98%로, 액상은 야자섬유에서 28.64%로, 기상은 왕겨숯에서 29.35%로 가장 높았다. 참취 시설재배지 토양개량제 시용함으로써 토양의 유기물함량 증가와 토양의 용적밀도 감소와 토양양 공극율 증가 등 토양의 물리 화학성을 개선할 수 있을 것으로 기대된다. 본 연구는 2년차 시험 결과로서 3년차에 재검토할 계획이다.

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