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Antitumor and Immunopotentiating Effects of Manda Enzyme

  • Hwang, Woo-Ik;Hwang, Yoon-Kyung;Lee, Ji-Young;Lee, Jae-Yeon;Okuda, Hiromichi
    • Natural Product Sciences
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    • v.2 no.1
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    • pp.29-36
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    • 1996
  • This study was to evaluate the antitumor and immunopotentiation effects of Manda Enzyme (ME). Oral administration of ME (0.2ml/mouse) to tumor bearing mice significantly prolonged survival rate compared to the control group with the prolongation ratio of 40%. The inhibition ratios for the first and the second experiments were 51.8% and 26.4%, respectively. Only the spleen index was significantly increased in the MEF-treated group, but not in the control group. Gamma globulin level of the MEF-treated group was elevated when mice were injected with sarcoma-180 cells on the left groin. Activities of natural killer (NK) and lymphokineactivated killer (LAK) cells were observed by $^{51}Cr-release$ method. Activities of NK cell against YAC-1 cells were significantly increased in the MEF treated group. And LAK cell activities against P815 cells were also significantly increased in the experimental group. These observations, therefore, suggest that ME may have an anticancer effect and immunopotentiating effect in vivo.

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A Study on Evaluation of Plastic Strain at Notch Tip of Weld HAZ in Steel (강 용접 열영향부 놋치 선단 의 소성 스트레인 평가에 관한 연구)

  • 김태영;임재규;정세희
    • Journal of Welding and Joining
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    • v.2 no.1
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    • pp.41-48
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    • 1984
  • Recrystallization technique was applied to analyze plastic strain at the notch tip of coarse grain HAZ in mild steel (SB 41) and high strength steel (SA 588). The notch tip of specimen was deformed by three point bending. Accumulated displacement (Crack Opening Displacement ${delta}t$) by the monotonic and cyclic loading under room temperature and hot strain embrittlement temperature ($250^{\circ}C$) was 0~1.0mm. Recrystallization heat treatment conditions were $650^{circ}C{ imes}3hr$ for SB 41 and $700^{circ}C{ imes}3hr$ for SA 588. The experimental results obtained were as follows ; 1) Distribution of the effective plastic strain at plastic zone was appeared by the function of crack opening displacement, and plastic zone or the effective plastic strain increased with crack opening displacement. 2) Plastic strain at notch tip of HAZ due to accumulated hot strain calculated as follows. .epsilon. over bar $_{p}$ = .epsilon. over bar $_{cr}$ (x/ $R_{x}$ ) $^{m}$ (m=0.25) 3) Work hardending ratio of notch tip for hot strain was linearly increased with .epsilon. over bar $_{max}$ and dependent upon the material types.s.

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RF 혼용 DC 스퍼터링 공정으로 증착된 ITO 박막 특성 및 유기태양전지 응용 연구

  • Im, Gyeong-A;Jeong, Seong-Hun;Gang, Jae-Uk;Kim, Jong-Guk;Kim, Do-Geun
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.389-389
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    • 2011
  • Transparent conductive oxide (TCO) 박막은 디스플레이 및 태양전지 등 광범위한 분야에서 적용되고 있으며, 특히 indium tin oxide (ITO)는 낮은 전기적 저항과 우수한 광투과도를 가지고 있어서 이미 많은 분야에 적용되고 있다. 본 연구는 RF와 DC를 혼용한 마그네트론 스퍼터링 공정을 활용하여 ITO 박막 특성 및 이를 활용한 유기태양전지 적용에 관한 것이다. UV-O3 처리된 glass 기판위에 thermal evaporation 방식으로 밀착력을 높이기 위하여 Cr을 5 nm 두께로 증착한 후 Al을 95 nm 증착하였다. 그 위에 스퍼터링 공정으로 ITO 박막을 In2O3:SnO2 target (10wt% SnO2)을 사용하여 1.0 mTorr의 공정압력(Ar:O2=30:1), 50W의 RF power 및 0.11kW의 DC power에서 50~250 nm의 두께로 증착하였다. ITO 박막의 결정구조 및 표면 형상은 x-ray diffraction (XRD) 및 scanning electron microscope (SEM)을 사용하여 분석하였으며, 전기적 특성은 four-point probe법으로 비저항값을 측정하였다. 또한 높은 광변환효율을 가지는 태양전지 제작을 위하여, 다양한 두께의 ITO 박막을 사용하여 ITO/ZnO/P3HT:PCBM/PEDOT/Ag 구조의 유기태양전지를 제작하여 소자 특성을 최적화 하였다.

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The Study of Cochineal Dyeing. (코치닐의 염색성에 관한 연구)

  • 주영주;소황옥
    • Textile Coloration and Finishing
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    • v.10 no.1
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    • pp.11-19
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    • 1998
  • For the purpose of standardization and practicability of dyeing by natural dyes, the mordanting and dyeing properties of cochineal and carminic acid were studied. Appropriate extraction, dyeing and mordanting condition of cochineal were determined, and the effect of mordanting method on dye uptake and color fastness of dyed fabric was investigated. The maximum absorbance of cochineal solution was 495nm, carminic acid was 533nm and 577nm. The color of carminic acid solution was affected by pH 6~9. The optimum temperature to extract cochineal was $80-100^\circ{C}$ and dyeing solution for 1 hour. And effective dyeing time to silk was 60min. Effective mordanting temperature was $80^\circ{C}$, and its time was 30min. In case mordants concentration, the maximum absorbance of Sn solution was 3%, K, Cu and Cr were in 1%. K/S value of dyeing fabrics was recoginazed by mordant treatment, specially Fe, Sn, Al, Cu. In the case of cochineal light fastness was increased by mordant treatment, specially Fe treatment. Perspiration fastness was good in acidic solution than in alkaline solution and perspiration fastness of cochineal was poor. Fastness of abrasion and dry-cleaning were good and these fastness improvement were generally effective for post-mordanting treatment.

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Characteristics of Heavy Metallic Elements of PM10 for Yellow sand and Non-Yellow sand during Springtime of 2002 at Busan (2002년 부산지역 봄철 황사/비황사시 PM10 중의 중금속 농도 특성)

  • Jeon, Byung-Il
    • Journal of Environmental Impact Assessment
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    • v.12 no.2
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    • pp.99-108
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    • 2003
  • We collected and analyzed PM10 samples to account for the characteristics of heavy metallic elements for yellow sand and non-yellow sand during springtime of 2002 at Busan, The mean PM10 mass concentration for springtime of 2002 was $219.82{\mu}g/m^3$ with the maximum $787.50{\mu}g/m^3$ and the minimum $19.44{\mu}g/m^3$. The mean concentration of metallic elements contained in PM10 are shown as follows : Si>Ca>Fe>Al>Na, respectively. The ratio of mean PM10 mass concentration for yellow sand($362.7{\mu}g/m^3$) to that for non-yellow sand($48.3{\mu}g/m^3$) was 7.5, the significant positive correlation (P<0.05) was found between yellow sand and non-yellow sand. The metallic elements concentration ratios of yellow sand to the non-yellow sand were over 10 times for Al, Ca, Mg, 4~8 times for Fe, Si, Mn. But the concentration of Na, Cu, Zn for non-yellow sand was higher than those of yellow sand. The crustal enrichment factor of Cd, Cu, Pb, Zn, Cr, K, Mn, Na, Ni for yellow sand was higher that of non-yellow sand over 10 times, and concentration rate of soil particles of yellow sand was increased 2.3 times that of nonyellow sand.

Preparation and Characterization of Chitosan/Cellulose Acetate Blend Film (키토산/셀룰로오스 아세테이트 복합필름의 제조와 특성)

  • Jung, Young-Jin;An, Byung-Jae;Choi, Hae-Wook;Kim, Hong-Sung;Lee, Young-Hee
    • Textile Coloration and Finishing
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    • v.19 no.4
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    • pp.10-17
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    • 2007
  • Chitosan(CS) and cellulose acetate(CA) composite films were prepared using formic acid as a cosolvent by casting, solvent evaporating and neutralization method. This study examines if the blending method, which uses formic acid as a cosolvent is efficient in improving the mechanical properties of CS film, especially wet strength and elongation. Formic acid is an effective cosolvent for the blend of CS and CA. Under wet condition, tensile strength and elongation of the composite films were obviously higher than those of the films made from pure CS. FTIR, DSC, and X-ray diffraction showed that the composite films exhibit a high level of compatibility and that strong interaction between the CS and CA was caused by intermolecular hydrogen bonding. The affinity series of composite film to transition metal ions are Cu(II) > Cd(II) > Cr(III). The adsorption of Cu((II) ion was shown to be highly pH sensitive.

Regulation of Gene Expression for Amino Acid Biosynthesis in the Yeast, Sacchromyces cerevisiae

  • Lea, Ho Zoo
    • Proceedings of the Zoological Society Korea Conference
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    • 1995.10b
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    • pp.82-82
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    • 1995
  • Regulation of enzyme synthesis by transcriptional and translational control systems provides rather stable adaptation to change of amino acid level in the growth medium, while manipulation of enzyme activity through endproduct feedback inhibition represents rather short-term and reversible ways of adjusting metabolic fluctuation of amino acid level. Various control mechanisms interplay to regulate genes encoding enzymes for amino acid biosynthesis in the yeast, Sacchromyces cerevisiae. When amino acids are in short supply, genes under a cross-pathway regulatory mechanism Or general amino acid control (general control) increase their action, in which Gcn4p is the major positive regulator of gene expression. When cells are cultured in minimal medium, basal level expression is also regulated by supplementary control elements, where inorganic phosphate level is additionally involved. Most of amino acid biosynthetic genes are also regulated by the level of endproduct of the pathway. This pathway-specific regulatory mechanism is called specific amino acid control (specific controD, under which gene expression is reduced when endproduct is present in the medium. Derepression of a gene through general control can be usually overridden by repression through specific control, where the endproduct level of that particular pathway is high and not limiting. In this presentation, regulatory factors for basal level expression and general control of yeast amino acid biosynthesis will be discussed, m addition to pathway-specific repression patterns and interaction between CrOSS- and specific-control mechanisms. Preliminary results are also presented from the investigation of the cloned genes in the threonine biosynthetic pathway of the yeast. yeast.

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Chromium(III) recovery from tanning wastewater by adsorption on activated carbon and elution with sulfuric acid

  • Hintermeyer, Blanca H.;Tavani, Eduardo L.
    • Environmental Engineering Research
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    • v.22 no.2
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    • pp.149-156
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    • 2017
  • Chromium(III) recovery from tanning wastewater by means of adsorption on activated carbon and elution with sulfuric acid was studied. Tests were carried out at laboratory scale on an effluent of industrial origin. Initially, proteinaceous materials and fats were separated via sieving followed by ultrafiltration. The chemical composition of the sample thus precleansed was (in g/L): 1.09 chromium(III); 10.36 sulfate; 11.10 sodium; 9.57 chloride; 0.40 proteinaceous materials; and 0.20 fats. Adsorptions were made at 20, 30, and $40^{\circ}C$, establishing what temperature favored chromium(III) uptake. At $40^{\circ}C$, the maximum cation fixation was 40.2 mg/g, and the lowest content in an equilibrium solution was 3.9 mg/L. As regards sodium, chloride, and sulfate, the concentrations before and after the treatment were similar. Likewise, it was found that protons were also retained, modifying the pH of the liquid medium. Adsorption isotherms were analyzed using the Langmuir, Temkin, and Freundlich models. Finally, the extraction of the adsorbed tanning agent with sulfuric acid was evaluated. A recovery of 96.5% was achieved with 0.9 N at $70^{\circ}C$ (13.23 g/L $Cr^{3+}$; 42.98 g/L sulfate; and 0.40 g/L NaCl).

Treatment of Wastewater from Acetaldehyde Plant by Activated Sludge Process (활성슬러지 공정에 의한 Acetaldehyde 제조 공장 폐수의 처리)

  • Suh, Seung-Kyu;Kim, Jung-Ho;Kim, Young-Ho
    • Journal of Environmental Science International
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    • v.6 no.3
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    • pp.259-265
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    • 1997
  • This study was conducted to Investigate the treatment of wastewater from acetaldehyde manufacturing plant by activated sludge process with Micrococcus roseus AW-6, Micrococcus roseus AW-22, Microbacterium lacticum AW-38 and Mlcrobacterium nae- vaniformans AW-41. The $COD_{Mn}$ and $BOD_5$ of the wastewater were 5, 260mg/L and 6, 452mg/L, respectively. pH was 1.85. The main organic component in the wastewater was acetic acrid which was contained 67, 600mg/L. Optimum dilution time for activated sludge process was shown 10 times. The specific substrate removal rate(BL) was 1.95day-1 and the nonbiodegradable matters(Sn) were 23.2mg/L. Saturation constant (Ks) and mainmum specific growth rate(qmax) were 1, 640mg/L and 2.33day-1, respectively. Sludge yield coefficient(Y) and endogenous respiration coefficient(kd) were 0.28mg MLVSS/mgCOD and 0.02day-1, respectively. $COD_{cr}$ removal efficiency was 91% for 1.95day of hydraulic retention time.

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Shuffled Discrete Sine Transform in Inter-Prediction Coding

  • Choi, Jun-woo;Kim, Nam-Uk;Lim, Sung-Chang;Kang, Jungwon;Kim, Hui Yong;Lee, Yung-Lyul
    • ETRI Journal
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    • v.39 no.5
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    • pp.672-682
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    • 2017
  • Video compression exploits statistical, spatial, and temporal redundancy, as well as transform and quantization. In particular, the transform in a frequency domain plays a major role in energy compaction of spatial domain data into frequency domain data. The high efficient video coding standard uses the type-II discrete cosine transform (DCT-II) and type-VII discrete sine transform (DST-VII) to improve the coding efficiency of residual data. However, the DST-VII is applied only to the Intra $4{\times}4$ residual block because it yields relatively small gains in the larger block than in the $4{\times}4$ block. In this study, after rearranging the data of the residual block, we apply the DST-VII to the inter-residual block to achieve coding gain. The rearrangement of the residual block data is similar to the arrangement of the basis vector with a the lowest frequency component of the DST-VII. Experimental results show that the proposed method reduces the luma-chroma (Cb+Cr) BD rates by approximately 0.23% to 0.22%, 0.44% to 0.58%, and 0.46% to 0.65% for the random access, low delay B, and low delay P configurations, respectively.