• Journal of Acupuncture Research
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• 제39권3호
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• pp.213-221
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• 2022

Background: This study investigated the clinical effectiveness of Korean medicine (KM) treatment for shoulder impingement syndrome (SIS). Methods: There were 61 patients who were diagnosed with SIS in the Jaseng hospital network of KM (7 hospitals located in Korea: Gangnam, Daejeon, Bucheon, Haeundae, Bundang, Ulsan, and Gwangju) between January 1^st, 2015 and December 31^st, 2020 who were retrospectively reviewed. The patients were grouped according to complications, intake of analgesics, duration of illness preadmission, and treatment. Treatments consisted of herbal medicine, acupuncture, cupping, Chuna, pharmacopuncture, bee venom pharmacopuncture, medicinal steaming, Daoyin exercises, and physical therapy. By comparing the Numeric Rating Scale (NRS), Shoulder Pain and Disability Index, and European Quality of Life 5-Dimensions questionnaire scores, the effectiveness of integrated KM treatment was evaluated. Results: There were 14 males and 47 females. For inpatients diagnosed with SIS, the mean NRS score decreased from 5.78 ± 1.33 to 3.40 ± 1.43 (p < 0.001). The mean Shoulder Pain and Disability Index score decreased from 53.87 ± 14.76 to 38.56 ± 18.87 (p < 0.001), and the mean European Quality of Life 5-Dimensions questionnaire increased from 0.67 ± 0.13 to 0.76 ± 0.09 (p < 0.001) after KM treatment. Medicinal steaming (0.398; p < 0.001), acupuncture (0.290), cupping (0.288), bee venom pharmacopuncture (0.282), and Daoyin exercises (0.262; p < 0.05) had a positive correlation with improved changes in the NRS score. Conclusion: Conclusion: Treatment with integrated KM treatment improved the pain, range of motion, shoulder function, and quality of life of patients with SIS.

• Nuclear Engineering and Technology
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• 제53권10호
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• pp.3398-3405
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• 2021

This study observed the effect of neutron irradiation and ageing on the microstructure, hardness, and corrosion resistance of SAV-1 (Al-Mg-Si) alloy. The investigated material was irradiated with neutrons to fluences of 10²¹-10²⁶ n/m² in the WWR-K research reactor and kept in dry storage. Long-term irradiation led to an increase in hardness of the alloy and a deterioration of pitting corrosion resistance. Post-irradiation ageing for 1 h at 100-300 ℃ resulted in a decrease in microhardness of the irradiated SAV-1. The effect of post-irradiation ageing on pitting corrosion was made clear through the formation of Guinier-Preston zones and secondary precipitates in the Al matrix. Ageing at 250 ℃ corresponded to the development of stable microstructure and the highest corrosion resistance for the irradiated samples. Mg₂Si, Si, and needle-shaped β" precipitates were formed in SAV-1 alloy that was irradiated with low fluences. β" and clusters of rod-shaped B-type precipitates were observed in highly irradiated samples. The precipitates were similar to those seen in non-irradiated pseudo-binary Al-Mg₂Si alloys with Si excess.

• Nuclear Engineering and Technology
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• 제53권5호
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• pp.1717-1722
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• 2021

This study is devoted to the ability of carbon fiber material samples impregnated with various amounts of barium iodide and triethylenediamine to remove radioactive methyliodide from air streams. The main sorption characteristics of impregnated UVIS® carbon fiber were determined and the use of this material for purifying of technological gas flows at nuclear power plants was evaluated. The methyliodide trapping efficiency by samples impregnated with barium iodide, TEDA, and their mixture was 83.4 ± 0.8%; 93.1 ± 0.6% and 93.5 ± 0.7% respectively, under the same conditions. The study established a significantly higher capacity (8.3 ± 0.07 mg/cm²) of samples impregnated simultaneously with both chemical compounds toward methyliodide. Under the same test conditions, the values of this parameter for the samples impregnated separately with TEDA and BaI₂ were 2.85 ± 0.05 mg/cm² and 0.86 ± 0.04 mg/cm², respectively.

• Journal of Korean Neurosurgical Society
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• 제30권sup1호
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• pp.5-12
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• 2001

This study was designed to investigate the mechanism of cell death after cisplatin treatment in human glioblastoma A172 cells. Cis-diamminedichloroplatinum(Cisplatin) demonstrated cytostatic or cytotoxic effects on A172 cells in a dosedependent manner. Cisplatin-mediated cytotoxity in A172 cells was revealed as an apoptosis characterized by high molecular weight DNA fragmentation by agarose electrophoresis as well as nuclear fragmentation by Hoechst staining. Cisplatin also resulted in the activation of caspase 3-like protease as well as poly(ADP-ribose) polymerase(PARP) cleavage. Interestingly, the anti-apoptotic Bcl2 protein was degraded and furthermore, expression of p53 protein was increased by cisplatin in a time-dependent manner. Taken together, these results suggest that anticancer drug, cisplatin induces the apoptotic death of human glioblastoma A172 cells via the activations of caspase 3-like protease, degradation of anti-apoptotic Bcl2 protein and increase in the expression of p53.

• 한국해양생명과학회지
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• 제1권1호
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• pp.1-7
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• 2016

낙동강 하구역과 부산연안해역에서 분변계 대장균의 계절적, 해역별 분포특성을 파악하기 위해, 2013년 2월부터 2015년 11월까지 계절 조사를 수행하였다. 아울러 부산연안해역의 오염 정도와 해역의 지리학적 특성을 바탕으로 25개 정점을 5개의 구역(I, II, III, IV, V)을 나누어 평가하였다. 조사기간 중 수온과 염분은 각각 7.50~27.64℃와 16.82~34.82 psu의 범위로 관찰되었고, 수온은 전형적인 온대지역의 특성을 보였다. 염분은 2014년 하계 구역 IV에서 구역 III까지 광역해역에 걸쳐 저염분화 현상이 나타나, 대장균의 증식을 가속화시켰다. 대장균 E. coli는 2015년 추계 정점 1(지역 I)에서 6,000 cfu l^-1로 최고치를 기록되었고, 외측 구역 III에서 상대적으로 낮게 관찰되었다. 수온은 대장균 E. coli과 유의한 상관성이 관찰되지 않았지만(p>0.05), 상대적으로 고수온조건에서 대장균 밀도가 높게 나타났다. 아울러 대장균 밀도는 염분농도와 음(r=-0.53 p<0.05)의 상관관계를 보였고, 해역의 저염분화 현상은 대장균의 증식 및 유지에 중요한 촉진제 역할을 한 것으로 파악되었다. 결과적으로 부산연안해역에서 하계 집중강우로 인한 육상기원 담수 유입으로 분변계 대장균이 지역 IV과 지역 III에서 현저하게 영향을 미쳤고, 계절에 관계없이 수영만에서 높은 대장균 밀도가 관찰되어 오염화 현상이 두드러졌다.

• Journal of Microbiology and Biotechnology
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• 제25권9호
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• pp.1532-1536
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• 2015

To investigate the memory-enhancing effect of lactic acid bacteria, we selected the probiotic mixture KF, which consisted of Lactobacillus plantarum KY1032 and Lactobacillus curvatus HY7601 (1 × 10¹¹ CFU/g of each strain), and investigated its antilipidemic and memoryenhancing effects in aged Fischer 344 rats. KF (1 × 10¹⁰ CFU/rat/day), which was administered orally once a day (6 days per week) for 8 weeks, significantly inhibited age-dependent increases of blood triglyceride and reductions of HDL cholesterol (p < 0.05). KF restored agereduced spontaneous alternation in the Y-maze task to 94.4% of that seen in young rats (p < 0.05). KF treatment slightly, but not significantly, shortened the escape latency daily for 4 days. Oral administration of KF restored age-suppressed doublecortin and brain-derived neurotrophic factor expression in aged rats. Orally administered KF suppressed the expression of p16, p53, and cyclooxygenase-2, the phosphorylation of Akt and mTOR, and the activation of NF-κB in the hippocampus of the brain. These findings suggest that KF may ameliorate age-dependent memory deficit and lipidemia by inhibiting NF-κB activation.

• 한국수산과학회지
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• 제53권4호
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• pp.620-627
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• 2020

Oxygen consumption and blood physiology of olive flounder Paralichthys olivaceus (mean body weight 106.6±6.8 g, mean±SD) was investigated at salinities of 34.0 (control), 33.7, 33.3, 32.6, 31.3, 28.6, 23.1, 12.2 and 0.0 psu at 20.0℃, respectively. Stepwise salinity changes (34.0→33.7→33.3→32.6→31.3→28.6→23.1→12.2→0.0 psu) with an interval of 24 h for each salinity induced a significant (P<0.05) increase of oxygen consumption rate (OCR) in fish exposed from 31.3 to 0.0 psu compared to that of control fish. The maximum OCR was found in fish exposed to 23.1 psu, which was accompanied by 36.2% higher energy consumption than the control fish. Fish exposed to each salinity for 24 h induced a significant decrease of blood plasma Na⁺ in 0.0 psu and Cl^- in 12.2 and 0.0 psu (P<0.05), and increase of plasma glutamic oxaloacetic transaminase (GOT) in 0.0 psu compared to the control fish (P<0.05). The results of this experiment show that P. olivaceus exposed to concentrations below 31.3 psu requires more energy costs to adapt to salinity changes than 34.0 psu under our experimental conditions.

• 한국초지조사료학회지
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• 제42권1호
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• pp.47-53
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• 2022

The objective of this study was to verify the effect of pig slurry application with acidification and biochar on feed value, nitrogen use efficiency (NUE) of maize forage, and ammonia (NH₃) emission. The four treatments were applied: 1) non-pig slurry (only water as a control, C), 2) only pig slurry application (P), 3) acidified pig slurry application (AP), 4) acidified pig slurry application with biochar (APB). The pig slurry and biochar were applied at a rate of 150 kg N ha^-1 and 300 kg ha^-1, respectively. The AP and APB treatments enhanced all feed values compared to C and P treatments. The NUE for plant N was significantly increased 92.1% by AP and APB treatment, respectively, compared to the P treatment. On the other hand, feed values were not significantly different between AP and APB treatments. The acidification treatment with/without biochar significantly mitigated NH₃ emission compared to the P treatment. The cumulative NH₃ emission throughout the period of measurement decreased by 71.4% and 74.8% in the AP and APB treatments. Also, APB treatment reduced ammonia emission by 11.9% compared to AP treatment. The present study clearly showed that acidification and biochar can reduce ammonia emission from pig slurry application, and pig slurry application with acidification and biochar exhibited potential effects in feed value, NUE, and reducing N losses from pig slurry application through reduction of NH₃ emission.

• Nutrition Research and Practice
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• 제15권sup1호
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• pp.53-69
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• 2021

BACKGROUND/OBJECTIVES: To determine the weight change trend among the adult Turkish population after 1 yr of the coronavirus disease 2019 (COVID-19) pandemic and factors associated with weight change. MATERIALS/METHODS: This cross-sectional study was conducted between 26 February and 6 March 2021 using an online questionnaire that included questions for sociodemographic variables, eating habits, stress level, and the Three-Factor Eating Questionnaire-R18. Those who weighed themselves 1-2 weeks before the pandemic was declared in Turkey and remembered their weight were invited to participate in the study. Trends in weight and body mass index (BMI) change were calculated. The variables associated with a 1% change in BMI were assessed using hierarchical regression analysis. RESULTS: The study was conducted with 1,630 adults (70.25% female) with a mean age of 32.09 (11.62) yrs. The trend of weight change was found to increase by an average of 1.15 ± 6.10 kg (female +0.72 ± 5.51, male +2.16 ± 7.22 kg) for the first year of the COVID-19 pandemic. The rate of participants with a normal BMI (18.50-24.99 kg/m²) decreased to 51.91% from 55.75%. Consuming an "Increased amount of food compared to before the pandemic" was found to be the independent variable that had the strongest association with a 1% increase in BMI (β = 0.23 P < 0.001). The average change in the BMI was higher in older individuals than in those who were younger. A high stress level was associated with a decrease in BMI (β = -0.04 P = 0.048). CONCLUSIONS: In this study, the factors associated with weight change after 1 yr of the pandemic in the Turkish population was reported for the first time. A high stress level and increased weight gain trend still occur in Turkey after 1 yr of the pandemic.

• Bulletin of the Korean Chemical Society
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• 제30권7호
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• pp.1655-1657
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• 2009