• Asian Pacific Journal of Cancer Prevention
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• 제14권8호
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• pp.4549-4552
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• 2013

The incidence of gastric cancer worldwide, and in particular in developing countries, has shown a marked increase. Poor prognosis of gastric cancer patients occurs due to the rapid metastasis of the disease via the lymphatic and blood vessels. The aim of this study was to investigate the expression and the clinical significance of D2-40 and CD34 in human gastric cancer. D2-40 and CD34 expression wasdetected in 1,072 cases of Chinese patients with gastric carcinoma using immunohistochemistry. The lymphatic vessel density (LVD) and microvessel density (MVD) were calculated and analyzed and the correlation with the clinicopathological factors and prognosis was determined. The LVD and MVD of the gastric cancer cases were significantly higher compared to those of normal tissues (P < 0.05). The expression of D2-40-LVD and CD34-MVD in the malignancies were positively related to the age, tumor size, invasion depth, lymphatic metastasis and pathological tumor-node-metastasis (pTNM) (P < 0.05); However, no statistically significant difference was identified between them with the patient gender (P > 0.05). Up-regulation of D2-40 and CD34 expression was significantly correlated with the poor survival rate in univariate and multivariate analyses. The LVD marked by D2-40 and the MVD marked by CD34 were positively correlated to the clinicopathological factors of the malignancies and may play important role in the development and progression of gastric cancer.

• 한국보건간호학회지
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• 제34권3호
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• pp.355-367
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• 2020

Purpose: This study aims to identify factors influencing the health-related quality of life among women merchants at traditional markets. Methods: Participants in this cross-sectional descriptive study included 121 women merchants. Data were collected from May 01 to June 30, 2019 using the patient health questionnaire-9 (PHQ-9), psychosocial well-being index-short form (PWI-SF), subjective health status, and HRQoL. Selected data were analyzed using descriptive statistics, Pearson's correlation coefficient, and stepwise multiple regression by applying the SPSS/WIN program 22.0. Results: The HRQoL was significantly different by age (F=5.87, p=.001), education (F=2.98, p=.022), working period (F=4.70, p=.004), exercise (t=2.20, p=.030), chronic disease (t=-2.57, p=.011), BMI (F=5.04, p=.008), depression (F=4.70, p=.004), stress (F=7.82, p<.001), and subjective health status (F=7.91, p=.001). Factors influencing the HRQoL for women merchants included BMI (β=-.35, p<.001), subjective health status (β=.33, p<.001), and stress (β=-.18, p=.021). The explanation power of this regression model was 29.8% (F=5.51, p<.021). Conclusion: BMI, subjective health status, and stress affect the HRQoL of the subjects evaluated. Therefore, there is a need for health management programs that may decrease stress, control the BMI, and improve the subjective health status of women merchants at traditional markets.

• 한국분말야금학회:학술대회논문집
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• 한국분말야금학회 1996년도 추계학술강연 및 발표대회 강연 및 발표논문 초록집
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• pp.34-35
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• 1996

• 한국자기학회:학술대회 개요집
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• 한국자기학회 2004년도 하계학술연구발표회 논문개요집
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• pp.34-34
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• 2004

• 한국융합학회논문지
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• 제10권12호
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• pp.453-463
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• 2019

본 연구는 동 학년 동료 교수학습 기반 자율실습이 간호대학생의 핵심기본간호술 숙련도, 수행자신감 및 자아효능감에 미치는 효과를 규명하기 위한 비동등성 대조군 전·후 유사실험연구이다. 자료수집은 K시 소재 일개 전문대학 간호학과 2학년에 재학 중인 실험군 34명, 대조군 34명의 총 68명을 대상으로 2019년 5월 1일부터 6월 12일까지 시행되었다. 연구결과 동료 교수학습 기반 자율실습을 적용한 실험군과 적용하지 않은 대조군 간 유치 도뇨의 숙련도(t=11.60, p<.001), 수행자신감(t=4.12, p<.001), 보호장구 착용과 폐기물 관리의 숙련도(t=5.91, p<.001), 수행자신감(t=4.24, p<.001), 배출 관장의 숙련도(t=2.82, p=.008), 수행자신감(t=2.09, p=.044) 및 자아효능감(t=4.52, p<.001)은 통계적으로 유의한 차이가 있었다. 결과적으로 동료 교수학습 기반 자율실습은 핵심기본간호술 숙련도와 수행자신감 및 자아효능감 향상에 긍정적인 효과를 나타내었으며, 기존 자율실습을 보완할 수 있는 효율적인 방안으로의 활용 가능성이 확인되었다. 이를 토대로 향후 동료 교수학습을 다양한 전공과목에 확대 적용하여 효과를 검정하는 연구를 제언한다.

• 디지털융복합연구
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• 제17권5호
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• pp.319-326
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• 2019

본 연구는 대학생의 생활스트레스가 공격성에 미치는 영향을 파악하기 위해 시도되었다. 연구대상은 D시에 재학중인 대학생 262명이었으며, 자료수집 기간은 2017년 9월 5일부터 7일까지 3일간이었다. 연구도구는 대학생활스트레스 도구와 공격성 도구를 사용하였으며, 자료분석은 IBM SPSS 25.0 프로그램을 사용하였다. 본 연구결과는 다음과 같다. 대상자의 생활스트레스는 학업관련 스트레스가 가장 높았다. 일반적 특성에 따른 공격성은 성별(t=4.43, p<.001), 전공(F=13.66, p<.001)에 따라 유의한 차이가 있었으며, 대학생의 공격성은 대인관계 문제(r=.49, p<.001), 학업 문제(r=.34, p<.001), 경제 문제(r=.34, p<.001), 장래 문제(r=.35, p<.001), 가치관 문제(r=.31, p<.001)와 각각 양의 상관관계가 있었다. 대학생의 공격성에 영향을 미치는 요인으로는 대인관계 문제, 자연계열 전공, 학업 문제로 이들 요인은 공격성을 30% 설명하였다. 본 연구를 통하여 대학생의 생활스트레스의 정도 및 공격성에 영향을 미치는 요인들을 파악할 수 있었으며, 이를 통하여 대학생의 공격성 관리를 위한 프로그램 구성의 방향을 제시했다는 점에서 연구의 의의를 둘 수 있다.

• 수도
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• 통권65호
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• pp.34-43
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• 1993

• 건설안전기술
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• 제3권2호통권8호
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• pp.24-34
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• 1993

• 건축사
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• 통권646호
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• pp.34-35
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• 2023

• 한방재활의학과학회지
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• 제25권1호
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• pp.17-26
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• 2015

Objectives This study was carried out to investigate the experimental effects of Lonicerae Caulis and Bee-venom Acupuncture in Yanglingquan (陽陵泉, GB34) that have clinical efficacy in the Rheumatoid Arthritis. Methods Materials of present study are Lonicerae Caulis Extracts (LCE), Bee-Venom Acupuncture (BVP), Sprague-dawley rats (250 g or so, ♂), and various kinds of needing experimental studies. We measured several experimental items of the rats with the arthritis induced by Freund's complete adjuvant (0.2 ml/kg), such as body weight, rate of paw edema, analgesic effect by hot plate method, WBC, TNF-${\alpha}$ cytokine and IL-10 cytokine. Rats were divided into four groups; Normal group that was treated with normal saline 1.0 ml (o.p) and $15{\mu}l/kg$ (GB34) to normal rats, Control group that was treated with normal saline 1.0 ml (o.p) and $15{\mu}l/kg$ (GB34) to pathologic model rats induced by Freund's complete adjuvant 0.2 ml/kg, Experimental group A that was treated with LCE 1.0 ml (o.p) and normal saline $15{\mu}l/kg$ (GB34) to pathologic model rats induced by Freund's complete adjuvant 0.2 ml/kg and Experimental group B that was treated with LCE 1.0 ml (o.p) and BVP $15{\mu}l/kg$ (GB34) to pathologic model rats induced by Freund's complete adjuvant 0.2 ml/kg, and the experiment took over after 28 days. The results were analysed using SPSS for windows 12.0. Results Experimental group A showed the increase in body weight, paw licking times and IL-10 cytokine compared to Control group. Also it was decreased in rate of paw edema, WBC, and TNF-${\alpha}$ cytokine compared with Control group. Experimental group B showed the increase in body weight, paw licking times, and IL-10 cytokine compared to Control group, and showed the decrease in rate of paw edema, WBC and TNF-${\alpha}$ cytokine compared to Control group. Especially TNF-${\alpha}$ cytokine and rate of paw edema were accepted statistical significance compared with Control group. Conclusions It is suggested that Lonicerae Caulis (o.p) and Bee-venom Acupuncture (GB34) can be used in the treatment of rheumatoid arthritis.