• JSTS:Journal of Semiconductor Technology and Science
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• 제2권3호
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• pp.157-163
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• 2002

A new flash EEPROM device with p^＋ poly-Si control gate and n^＋ poly-Si floating side gate was fabricated and characterized. The n^＋ poly-Si gate is formed on both sides of the p^＋ poly-Si gate, and controls the underneath channel conductivity depending on the number of electron in it. The cell was programmed by hot-carrier-injection at the drain extension, and erased by direct tunneling. The proposed EEPROM cell can be scaled down to 50 nm or less. Shown were measured programming and erasing characteristics. The channel resistance with the write operation was increased by at least 3 times.

• 한국의류산업학회지
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• 제10권2호
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• pp.228-235
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• 2008

The purpose of this study is to examine the functionality with material-improved working uniform(protocol, P) and current working uniform(control, C). Movement functionality evaluation of material-improved working uniform was carried out through sensory evaluation of working uniform. And Oxygen uptake was explored to different working uniform(P, C) in relation to a physiological functionality measurement. The results have been shown as follows: It was found that the workers feel uncomfortable with the parts of the wrist, the back width, the shoulder seam and the side in the current working uniform when they move their arms up and down, but the inconvenience has been reduced in the material-improved working uniform. And It was found that the workers feel uncomfortable with the parts of the back width, the wrist and the side seam of the jacket, and the waist, the hips and the thigh of the trousers in the current working uniform when they move their waist, but the inconvenience has been reduced in the material-improved working uniform. In the current working uniform, it was also found that they feel uncomfortable with the parts of the horse riding position in which they stand straight in their slightly bended knees, with the parts of the hips, the side seam, the thigh and the knees when they crouch down, and with the parts of the hips and the thigh when they put one of their legs onto a higher place. However, the inconvenience was reduced in the material-improved working uniform. Oxygen uptake, which was measured to assess physiological dressing functionality, was found to be higher when people work in an uncomfortable uniform than when they work in a uniform of better functionality by an increase in metabolic rate, which can be a cause of workers' inefficiency of fatigue.

• 대한물리의학회지
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• 제8권3호
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• pp.425-431
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• 2013

PURPOSE: The purpose of this study was to examine the effect of visual control on gait speed and balance in patients with stroke. Static balance and gait speed were investigated with comparison and fixed direction of visual. METHODS: We included twenty-six patients with stroke. Participants were measured static balance while standing on a forceplate with one of 4 different visual direction in front, floor, non-affected side and affected side for 30 seconds. To compare of the gait speed, participants had to walk with one of fixed visual direction. And to compare of gait speed with visual dispersion, gait speed were measured with visual change in left and right, up and down direction every 5m, 2m and 1m intervals. RESULTS: The result of the static balance with fixed visual showed that the affected side and the non-affected side were shown significantly increased sway of total sway length, mediolateral distance, anteroposterior distance, average velocity(p<.05). The gait speed with fixed visual showed that affected side was significantly slower(p<.05). And the gait speed significantly increased as interval of visual dispersion decrease in the sagittal and horizontal plane(p<.05). CONCLUSION: The results from this study showed that the visual direction effected on static balance and the faster visual movement made to increase the gait speed. Therefore the rehabilitation training with visual control may be implemented for stroke patients.

• 한국전문물리치료학회지
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• 제26권4호
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• pp.35-41
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• 2019

Background: Obstacle training affects lower limb muscle activity, balance, reducing the risk of falls, and making gait more stable. Objects: This study aimed to investigate the effects of aquatic and ground obstacle training on balance and muscle activity in patients with chronic stroke. Methods: The study subjects included 30 patients with stroke, who were divided into aquatic ($n_1=15$) and ground ($n_2=15$) groups. Groups underwent obstacle training three times per week, 30 min per session, for six weeks that went as follows: walking over sites with the paralyzed leg, stepping onto and down from a box step, and walking over obstacles with the non-paralyzed leg. Results: The experimental results were obtained by comparing muscle activity. Activity of the rectus femoris, biceps femoris, tibialis anterior, and gastrocnemius were significantly increased in the aquatic group (p<.05). Activity of the biceps femoris and tibialis anterior were significantly increased in the ground group (p<.05); however, the rectus femoris and gastrocnemius were not significantly different. In the comparison of maximal distance regarding the limits of stability, it was significantly increased on the non-affected side, affected side, and anterior and posterior distance in the aquatic group (p<.05). It was significantly increased in the non-affected side and anterior and posterior distance the ground group (p<.05); however, maximal distance on the affected side distance was not significantly different. Conclusion: Gait training with aquatic and ground obstacles is effective for improving balance and gait ability of patients with stroke. However, it was more effective for the aquatic group than for the ground group.

• PNF and Movement
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• 제9권1호
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• pp.1-9
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• 2011

Purpose : The purpose of this study is to analyze the effect of closed-chain exercise on weight supporting rate change within hemiplegic side and static dynamic balance ability in stroke patients. Methods : The subjects of the study were 13 hemiplegic patients who carried out closed-kinematic chain exercise program over 6 weeks. The exercises of the program are stand to sit with stall bar, stair-up & down by a hemiplegic leg and bridging exercise crossing the non-hemiplegic leg onto the hemiplegic leg. Each exercise was carried out over 3 sets of 10reps. Results : The results of this study were summarized as follows: 1. After intervention, there was a statistically significant change in the weight supporting rate within hemiplegic and non-hemiplegic side(P<0.05). 2. After intervention, there was a statistically significant change in the static balance(FICSIT-4) ability(P<0.05). 3. After intervention, there was a statistically significant change in the dynamic balance(FSST, TUG, FRT) ability(P<0.05). Conclusion : The results of the study suggests that closed-chain exercise program in stroke patients improves their weight supporting rate and enhance the static dynamic balance.

• 한국멀티미디어학회논문지
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• 제19권2호
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• pp.352-359
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• 2016

This paper presents high efficiency 5A synchronous DC-DC buck converter. The proposed DC-DC buck converter works from 4.5V to 18V input voltage range, and provides up to 5A of continuous output current and output voltage adjustable down to 0.8V. This chip is packaged MCP(multi-chip package) with control chip, top side P-CH switch, and bottom side N-CH switch. This chip is designed in a 25V high voltage CMOS 0.35um technology. It has a maximum power efficiency of up to 94% and internal 3msec soft start and fixed 500KHz PWM(Pulse Width Modulation) operations. It also includes cycle by cycle current limit function, short and thermal shutdown protection circuit at 150℃. This chip size is 2190um*1130um includes scribe lane 10um.

• Asian Pacific Journal of Cancer Prevention
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• 제16권5호
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• pp.2087-2092
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• 2015

Nowadays herbal-derived medicines are attracting attention as new sources of drugs with few side effects. Silibinin is a flavonoid compound with chemotheraputic effects on different cancers such as examples in the prostate, lung, colon and breast. In the present study, the cytotoxic effects of silibinin on MCF7 breast cancer cells were investigated. Apoptosis was determined by flow cytometry and the impact of silibinin on the expression of pivotal genes including Bak, P53, P21, BRCA1, BCL-X1 and ATM was analyzed. Treatment for 24h had a significant dose-dependent inhibitory effect on cell growth (p<0.05) with dose- and time- dependent induction of apoptosis (p<0.05). In addition, there were significant increases in BRCA1, ATM, Bak and Bcl-XL gene expression at the mRNA level with different concentrations of silibinin for 24 or 48 h (p<0.05). Taken together, the results suggest that silibinin inhibits the proliferation and induces apoptosis of MCF-7 cells by down-regulating Bak, P53, P21, BRCA1, BCL-Xl and thus may be considered as an effective adjuvant drug to produce a better chemopreventive response for the cancer therapy.

• 한국의류산업학회지
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• 제9권2호
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• pp.237-242
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• 2007

The purpose of this study is to examine the functionality with improved pattern-design working uniform(protocol, P) and current working uniform(control, C). Movement functionality evaluation of improved pattern-design working uniform was carried out through sensory evaluation of working uniform. Movements for the sensory evaluation consisted of four types of up and down and horizontal movements of the shoulders, four types of waist movements and five types of knee movements. The results have been shown as follows: The sensory value of back girth, wrist, side seam area of the "P" with the posture of raising an arm forward up to $90^{\circ}$ and the maximal arm's vertical movement significantly improved compared to the "C". Therefore, it can be concluded that movement functionality was increased with the improved pattern-design working uniform in the respect of arm's up and down movement. Furthermore, for P, Movement functionality improvements were shown in P with arm's horizontal movement, waist bending movement, and knee movement. Current working uniform(C) is jumper-type which wa designed without consideration for movement functionality of the arms and legs. But Pattern-design uniform(P) which was developed in this study. Therefore, the more patterns development, the better movement functionality in working uniform. The improved movement functionality improvements in working uniform will provide not only personal pleasantness but also efficiency of productivity at construction sites. In respect of human body's movement, further study for improved working uniform is required.

• Asian Pacific Journal of Cancer Prevention
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• 제16권12호
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• pp.4909-4913
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• 2015

Objective: To explore the preventive effect of aspirin on the cardiovascular complications in prostate cancer after endocrinotherapy. Materials and Methods: A total of 92 patients with prostate cancer were divided into observation group (n=44) and control group (n=48). The control group was treated with medical castration plus anti-androgenic drugs. Based on the above treatment, the observation group was added aspirin. The follow-up duration was 2 years. The changes of partial prothrombin time (PT), activated partial thromboplastin time (APTT), platelet aggregation rate (PAG), prostate-specific antigen (PSA) and serum testosterone (T) before and after treatment as well as incidence of cardiovascular disease were observed. Results: The 2-year survival rates of patients without cardiovascular disease in observation group and control group were 95.45% (42/44) and 72.92% (35/48), respectively, and significant difference was presented between two groups by comparison to the survival rates ($x^2=8.5453$, p=0.0035). There was no statistical significance between two groups as well as before and after treatment regarding PT (p>0.05). After treatment, APTT went down and PAG was gradually on the rise in control group, while PAG down and APTT on the rise increasingly in observation group. Significant differences were presented between two groups as well as before and after treatment (p<0.01). Both PSA and T levels were decreased significantly in two groups after treatment (p<0.01), but there was no statistical significant between two groups (p>0.05). Conclusions: Application of endocrinotherapy in prostate cancer can easily lead to occurrence of cardiovascular disease, but cardiovascular complications can be prevented by aspirin, without affecting the effect of endocrinotherapy.

• 한국환경과학회지
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• 제12권6호
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• pp.615-626
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• 2003

The applied model for this study area is WINFLOW using mite element method, It is thought that the simulation result by WINFLOW model under the steady flow state reflects well the ground water distribution within the reliability level which shows the error range of 1.1% to 8.0% from the comparison between the computed values and the observed, and analyzed that the constant head distribution is shown along the east-west direction and gentle and stable head gradient along the north-south direction. Ground water of the study area shows stable movement from the south to the stream area, and the particle trace for each location shows relatively linear shape from the upstream to the pumping location while the radius of influence according to the pumping amount shows a significant difference at the down stream area from the pumping location. The simultaneous pumping from P and P1 shows more complicated appearance, not the increase of the radius of influence than pumping from a single well P or P1, and it is analyzed that the particle path takes nearly linear form. It is known that the flow direction of the ground water and the velocity of the flow affect on the magnitude of the radius of influence of the wells from the fact that the more decreasing pattern of the ground water head is observed at the side of the well and the down stream area than the upstream area when the ground water moves from south to north regarding the radius of influence according to the pumping amount. Satisfactory results in analyses of ground water movement are obtained through the significant reduction of the physical uncertainties in the flow system as well as the relatively convenient model application using WINFLOW model which is proposed in this study.