• Journal of Korean Academy of Nursing
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• v.47 no.3
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• pp.406-419
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• 2017

Purpose: The aims of this study were to develop a motivational interviewing program for exercise improvement in persons with physical disabilities and to examine the effect of this motivational interviewing intervention. Methods: The study employed a nonequivalent control group pretest and posttest design. A total of 62 persons with physical disabilities (30 in the experimental group, 32 in the control group) were recruited from 2 community rehabilitation centers. The experimental group received 8 sessions of a group motivational interviewing program, scheduled once a week, with each session lasting 60 minutes. Test measures were completed before the intervention, immediately after the end of the intervention, 2 weeks later, and 6 weeks after the end of the intervention. Measures included self-efficacy for exercise, decisional balance for exercise, stage of change for exercise, regularity of exercise, exercise maintenance, and independent living ability. Data were analyzed using the ${\chi}^2-test$, Fisher's exact test, Independent samples t-test, and repeated measures ANOVA, conducted using IBM SPSS Statistics version 18. Results: The experimental group showed a significant increase in self-efficacy for exercise (F=50.98, p<.001), benefit (pros) of exercise (F=24.16, p<.001), and independent living ability (F=50.94, p<.001), and a significant decrease in loss (cons) of exercise (F=26.50, p<.001). There were significant differences between the two groups in stages of change for exercise (p<.001), regularity of exercise (p<.001), and exercise maintenance (${\chi}^2=26.61$, p<.001). Conclusion: The motivational interviewing program has the potential to improve exercise levels in persons with physical disabilities.

• Plant Resources
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• v.7 no.1
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• pp.39-46
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• 2004

To demonstrate the importance of transformation efficiency in independent event, molecular and cytogenetic analysis were conducted with genomic DNA and chromosome of transgenic plants produced by Agrobacterium tumefeciens LBA4404 (pSBM-PPGN: gusA and bar). Selection ratios of putative transgenic calli were similar in independent experiments, however, transformation efficiencies were critically influenced by the type of regeneration media. MSRK5SS-Pr regeneration mediun, which contains 5 mgL$^{-1}$ kinetin, 2% (w/v) sucrose in combination with 3% (w/v) sorbitol, and 500 mgL$^{-1}$ proline, was efficient to produce transgenic plant of rice from putative transgenic callus in the presence of L-phosphinotricin (PPT). With MSRK5SS-Pr medium, transformation efficincies of Nagdongbyeo were significantly enhanced from 3.7% to 6.3% in independent callus lines arid from 7.3% to 19.7% in plants produced, respectively. Stable integration and expression of bar gene were confirmed by basta herbicide assay, PCR amplification and Southern blotting of bar gene, and fluorescence in situ hybridization (FISH) analysis using pSBM-PPGN as a probe. In Southern blot analysis, diverse band patterns were observed in total 44 transgenic plants regenerated from 20 independent PPT resistant calli showing from one to five copies of T-DNA segments, however, the transformants obtained from one callus line showed the same copy numbers with the same fractionized band patterns.

• BMB Reports
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• v.41 no.10
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• pp.722-727
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• 2008

The present study compared the proteomic characteristics of a low passage number (L-33) and high passage number (H-81) LNCaP cell clone. Marked differences in protein expression were noted in the response of L-33 and H-81 cells to androgens. To investigate if regulation of these proteins was androgen-dependent, expression of the androgen receptor was silenced via small interfering RNA. Consistent with the proteomic data, abrogation of androgen receptor production in H-81 cells resulted in the reversed expression level into L-33 cells compared with non-treated H-81 LNCaP cells. The results clarify the progression into an androgen-independent phenotype.

• Korean Linguistics
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• v.79
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• pp.63-89
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• 2018

This study explores contrastive relation among voiced bilabial fricative [${\ss}$], voiceless bilabial stop [p] and glide [w] in Middle Korean consonant system based on Probabilistic Model. Preceding researches about voiced bilabial fricative [${\ss}$] proposed two influential arguments. One is voiced bilabial fricative [${\ss}$] was an independent phoneme, the other is it was not an independent phoneme but an allophone of voiceless bilabial stop [p] in Middle Korean. This study applies Probabilistic Phonological Relationship Model (PPRM) for solving the problem of dichotomy about contrastive and allophonic relations. The analysis result of the contrastive entropy by PPRM suggests that voiced bilabial fricative [${\ss}$] was just an allophone of voiceless bilabial stop [p] or glide [w] in Middle Korean. Comparing the entropies between [p] and other consonants with the entropies between [${\ss}$] and other consonants, a continuum defined in terms of entropy reveals that [${\ss}$] in Middle Korean was more allophonic than phonemic.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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• v.13 no.2
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• pp.45-54
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• 2007

The purpose of this study was effect of hamstring length on one leg stance test(OLST) in 108 persons. (men 28, women 80). The active knee extension test(AKE) was applied 3 times on both leg and high score was selected. Then, one leg stance test(OLST) was applied 3 times on both leg and high score was selected. Also, persons divided two group that is normal hamstring length group and shortening group). The result were as follows : 1. The correlation analysis between Lt. hamstring length and one leg stance time was no significant relation($p_{Lt.}=0.271$, $p_{Rt.}=0.051$). 2. The correlation analysis between Rt. hamstring length and one leg stance time was no significant relation($p_{Lt.}=0.837$, $p_{Rt.}=0.334$). 3. The independent T -test between Lt. hamstring normal (knee extension > 150degrees) & shortening group (knee extension ${\leq}$ 150 degrees) in Lt. leg stance time was no significant difference(p=0.73), but in Rt. leg stance time was statistically significant difference(p=0.04). 4. The independent T-test between Rt. hamstring normal (knee extension > 150degrees) & shortening group (knee extension ${\leq}$ 150 degrees) in one leg stance time was no significant difference($p_{Lt.}=0.09$, $p_{Rt.}=0.16$).

• Journal of the Korea Society of Computer and Information
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• v.25 no.7
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• pp.175-182
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• 2020

Fisher's classical method for combining independent p-values from continuous distributions is widely used but it is known to be inadequate for combining p-values from discrete probability distributions. Instead, the discrete analog of Fisher's classical method is used as an alternative for combining p-values from discrete distributions. In this paper, firstly we obtain p-values from discrete probability distributions associated with multi-sample location test data (Fisher-Pitman test and Kruskall-Wallis test data) by permutation method, and secondly combine the permutaion p-values by the discrete analog of Fisher's classical method. And we finally compare the combined p-values from both the discrete analog of Fisher's classical method and Fisher's classical method.

• Journal of Life Science
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• v.15 no.4 s.71
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• pp.542-547
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• 2005

Hypersensitivity of cells lacking Brcal to DNA interstrand .ross-link (ICL) agents such as cisplatin and mitomycin C(MMC) implicates the important role of Brcal in cellular response following ICL treatment. Brca1 plays an essential role in DNA double-strand break (DSB) repair through homologous recombination (HR)-dependent and -independent process. Recently, our group has been reported that Brca1 involves in cellular ICL response through HR-dependent repair process (Yun J. et at., Oncogene 2005). In this report, the involvement of Brca1 protein in HR-independent repair process is examined using isogenic $p53^{-/-}\;and\;p53^{-/-}\;Brcal^{-/-}$ mouse embryonic fibroblast (MEF) and psoralen cross-linked reporter reactivation assay. Brcal-deficient MEFs showed significantly low HR-independent repair activity compare to Brca1-proficient MEFs. Hypersensitivity to MMC and ICL reporter repair activity were restored by the reconstitution of Brca1 expression. Interestingly, MEFs expressing exon 11-deleted isoform of Brca1 $(Brca1^{\Delta11/\Delta11})$ showed high resistance to MMC and ICL reporter repair activity comparable to Brca1-reconstituted MEFs. Taken together, these results suggest that Brca1 involves in ICL repair through not only HR-dependent process but also HR-independent process using N-terminal RINC finger domain or C-terminal BRCT domain rather than exon 11 region which mediate interaction with Rad50.

• Korean Journal of Mathematics
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• v.27 no.1
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• pp.93-117
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• 2019

In this paper we wish to study some growth properties of entire functions represented by a vector valued Dirichlet series on the basis of (p, q)-th relative Ritt order, (p, q)-th relative Ritt type and (p, q)-th relative Ritt weak type where p and q are integers such that $p{\geq}0$ and $q{\geq}0$.

• Journal of Photoscience
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• v.9 no.2
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• pp.482-484
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• 2002

UV irradiation activates various intracellular signaling pathways causing cell death in a DNA damage-dependent and an independent manner. As DNA photoproducts, major forms of DNA damage, are maximally formed by UV light at 260-nm, short wavelength UV (UVC) is more harmful than middle wavelength UV (UVB). However, the differences or similarities in responses of DNA damage-independent intracellular signaling molecules to UVB and UVC are not elucidated. We examined activation of signaling molecules towards apoptosis in normal human fibroblastic cells after irradiation with UVB or UVC at a dose generating the equal amount of DNA photoproducts. Both UVB and UVC induced transient phosphorylation of ERK and sustained phosphorylation of p38. Phosphorylation of p53 at Ser15 and at Ser392 residues were also observed, which were inhibited by a phosphoinositide 3-kinase inhibitor, wortmannin. In contrast, an antioxidant N-acetyl-cysteine and a p38 inhibitor SB203580 suppressed only Ser392 phosphorylation, suggesting that UV-induced oxidative stress and p38 activation were involved in the phosphorylation of this site. The apoptic signals such as mitochondrial cytochrome C release and annexin V binding were then observed. Overall, no difference was found in chronological responses of p53, MAPK, and apoptosis between UVB-irradiated and UVC-irradiated cells. These results suggested that DNA damage-independent intracellular signaling molecules similarly responded to UVB and UVC when the equal level of DNA photoproducts were generated.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.12
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• pp.8234-8242
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• 2015

This study aims to explore ways to provide a high quality work environment services to social workers to analyze the relevance of relationships and exhaustion of the organizational environment, and the working environment and clients with disabilities living facility workers Gwangju and Jeonnam 252 people were targeting professionals working with people with disabilities living facility located on the main results are as follows. Organizational environment, work environment, organizational environment results by setting the relationship with the client as independent variables conducted a regression analysis to investigate the factors that influence independent of exhaustion (${\beta}$=-.200, p=.001) and Job environment (${\beta}$=-.460, p<.001) was a significant independent explanatory factor was 31.0%. However, relationships with clients (${\beta}$=-.059, p=0.258) were not significant factors in exhaustion. Consequently, practitioners must always have the confidence to actively work with pride and facilities are needed to improve the organizational environment and the working environment.