• Title/Summary/Keyword: p값 통합

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Combining Independent Permutation p-Values Associated with Multi-Sample Location Test Data

  • Um, Yonghwan
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.7
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    • pp.175-182
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    • 2020
  • Fisher's classical method for combining independent p-values from continuous distributions is widely used but it is known to be inadequate for combining p-values from discrete probability distributions. Instead, the discrete analog of Fisher's classical method is used as an alternative for combining p-values from discrete distributions. In this paper, firstly we obtain p-values from discrete probability distributions associated with multi-sample location test data (Fisher-Pitman test and Kruskall-Wallis test data) by permutation method, and secondly combine the permutaion p-values by the discrete analog of Fisher's classical method. And we finally compare the combined p-values from both the discrete analog of Fisher's classical method and Fisher's classical method.

Genetic Differentiation of the Mitochondrial DNA in Korean Salamander, Hynobius leechii (한국산 도룡뇽 (Hvnobius 1eechii)의 mitochondrial DNA 유전적 변이)

  • 이혜영;정은경
    • The Korean Journal of Zoology
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    • v.36 no.1
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    • pp.14-20
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    • 1993
  • 한국산 도룡농, Hvnobius leechii의 7개 집단에서 mitochondrial DNA(mtDNA)의 변이가 조사되었다. MtDNA의 크기에서의 차이는 관찰되지 않았으나 제한효소 인식 부위에서의 차이가 조사되었다. MtDNA의 절편 양상은 각 집단에서 동일하게 나타났다. 제한 효소로 처리하여 얻어진 절편의 비교에서 종내 변이는 염기 치환에 의하여 발생한 것임이 분석되어졌다. 특히 하동과 제주 집단은 몇개의 제한 효소 인식 위치에서 나머지 5개 집단과 뚜렷한 차이를 보였다. 염기치환율(p값)은 공통 절편 비율(p값)을 토대로 하여 얻어졌으며 그 값은 0.004에서 0.064의 범위 내의 값으로 측정되었다. 하동과 제주 집단을 제외한 5개 집단의 비교에서는 비교적 낮은 침의 염기 치환율을 보였으나 제주와 나머지 집단들과의 비교에서는 염기치환율이 높게 측정되었다. 염기 치환율과 관련지어 염기 분화 연대를 측정한 결과 도룡뇽 7개 집단은 3개의 group으로 나뉘어 졌으며 이들은 약 188만년전에 분화된 것으로 사료되어 진다.

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A Study on the Speciadon of a Fresh Water Fish Zacco temminckL VII. Vadation of Mitochondrial DNA between 2 Types of Zacco temmincki (갈겨니(Zacco temminki)의 진화에 관한 연구 VII.갈겨니 2 Type의 Mitochondrial DNA변이)

  • Lee, Hei-Yung;Yang, Suh-Yung;Paik, Sang-Gi;Park, Chang-Shin;Yu, Sung-Lim;Lee, Sung-Keun
    • The Korean Journal of Zoology
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    • v.31 no.3
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    • pp.236-242
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    • 1988
  • Mitochondrial DNAs of two Mdh allelotypes of the dark chub, Z. temmincki inhabiting in Korean fresh water, were analysed. Samples of each type were collected from four populations, and the fragment patterns for mtdNA of each type were explained from 7 of the eleven restriction enzymes with hexanucleotide recognition site. Genome size was approximately 16.7 kilobases. The highly typical mtdNA fragments of each type were discovered in digestion profiles produced by Eco RI and Pst I enzyrnes. The comparisons of restriction fragment patterns and relative digestion maps permitted the estimation of fragment homology (F) and nucleotide sequence divergence(p). Between the two identical types, sequence divergence(p) was 0.128(MS), and 0.045(MM), ; between the two different types, 0.195 (range 0.177-0.226). These result may provide a distinct difference more than the value derived from allozyrne analysis, and a powerful new molecular approach for assessing genetic-evolutionary relationship among fishes.

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Effects of Parent-Child Interaction Therapy on Parenting Skill and Children's Problem Behaviors: Meta-Analysis (부모-아동 상호작용치료가 양육기술과 아동의 문제행동에 미치는 영향: 메타분석)

  • Park, Min-Kyoung;Bak, Ah-Ream;Yoo, Doo-Han
    • The Journal of Korean Academy of Sensory Integration
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    • v.16 no.2
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    • pp.50-63
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    • 2018
  • Objective : The purpose of this study is to examine the effects of parent - child interaction therapy on parenting skills and children's problem behaviors by meta - analysis and to provide a basis for intervention methods. Methods : This study was conducted from January 2007 to March 2018 and the study was conducted using the parent-child interaction program for children with disabilities. PubMed and CINAHL, EBSCOhost, Science Direct were used to search for studies, and reference searching was also conducted as a secondary search option. A total of 7 studies was selected to meet the selection criteria, and the final 7 studies were assessed by using the Jadad scale. Statistical tests were performed using the R-meta-analysis program. Results : The effect size of parenting skill was large and the size of the effect of parenting stress was moderate. The children's problem behaviors also showed moderate effect sizes and all p-values were statistically significant (p < .0001). Conclusion : This study examined the effects of parent-child interaction therapy on parenting skills, parenting stress, and children's problem behaviors. Future research is needed to establish the basis for intervention for family involvement in pediatric occupational therapy.