• The Journal of Pediatrics of Korean Medicine
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• v.30 no.3
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• pp.108-120
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• 2016

Objectives The purpose of this study is to investigate Korean clinical studies on treatment of childhood obesity and to propose for better treatment options for childhood obesity. Methods Based on RISS, KISS, OASIS, KMbase with the keyword 'childhood obesity', 'child obesity', 'obese child', 'overweight child', total of 21 randomized controlled trials (RCTs), 11 single clinical studies, 3 chart reviews and 3 case reports have been found, and were analyzed. Results and Conclusion 1. Some study subjects were classified based on their sex - only men or women in a group or sometimes both. Another way of classify the study subjects were based on their age - preschooler, primary school students, middle school students, and high school students. The diagnostic criteria of the subjects were BMI (body mass index), Body fat percentage, Obesity index, Weight and unknown criteria. 2. The treatments used in 38 studies were exercise alone, education alone, both exercise and education or herbal therapy. The 7 studies that used herbal therapy as part of their study intervention had a study group with herbal intervention only and the other 2 study group with herbal treatment in addition to exercise and education. 3. 9 studies included herb medicines, electroacupuncture, auricular acupuncture, cupping, aroma massage, infrared light, and abdomen pad. Herb medications used in 5 studies included Chegameuiin-tang 2 kinds, Sobieum, Biman-tnag, and I-razin. 4. The methods of assessment used in 38 studies were classified by 7 categories and anthropometry parameters which is the basic methods are used in all studies 5. Almost studies (29 studies in all 38 studies) were using anthropometric parameters results on significantly effectiveness of childhood obesity. 6. More studies are needed to prove true effectives from various treatments, especially herbal therapy for childhood obesity.

• Korean Journal of Clinical Pharmacy
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• v.29 no.4
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• pp.278-285
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• 2019

Background: Rheumatoid arthritis is highly prevalent in overweight patients with type 2 diabetes mellitus and can be reduced by physical activity via altered proinflammatory parameters. However, the association between the frequency of physical activity and the prevalence of rheumatoid arthritis in prediabetic patients remains unclear and was evaluated in this study. Methods: Utilizing the Korean National Health Insurance Sharing Service database, 58,391 adults, who met the research criteria and underwent a general medical check-up between 2009 and 2013, were selected for this study. To analyze the data, a logistic regression with a proc survey logistic procedure was used. Results: The study revealed that the cumulative rheumatoid arthritis prevalence was lower in prediabetic patients compared to that in the control group (OR, 0.64; 95% CI, 0.483-0.840; p=0.001). More frequent physical activity (≥3 days/week) was significantly associated with a reduced rheumatoid arthritis prevalence in both groups (OR, 0.28; 95% CI, 0.039-0.521; p=0.044 vs. OR, 0.15; 95% CI, 0.063-0.237; p=0.007). Additionally, a 3.8-fold higher risk of rheumatoid arthritis development was observed in prediabetic adults with less frequent baseline physical activity (≤2 days/week). Overall, in prediabetes, the prevalence of rheumatoid arthritis was associated with the frequency of physical activity and not with the fasting plasma glucose levels. Conclusion: More frequent physical activity is associated with a low risk of developing rheumatoid arthritis in prediabetic patients. Thus, further studies are needed to confirm the clinical outcomes of frequent physical activity in rheumatoid arthritis prevention and control.

• Journal of Korean Medicine Rehabilitation
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• v.15 no.1
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• pp.67-75
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• 2005

목 적 : 면역 세포에서 주로 생성되는 사이토카인인 인터루킨-1 (interleukin-1)은 다양한 신경내분비계와 대사 기능에 영향을 미치며, 비만인의 말초혈액 단핵구에서 증가하는 경향이 있는 것으로 연구보고 되고 있다. 본 연구의 목적은 $IL-1{\alpha}$ 다형성과 사상체질이 비만과 관련이 있는지를 조사하는데 있다. 연구방법 : 본 연구에서는 현저한 체질량지수 (body mass index, BMI) 다양성을 보이는 건강한 한국 여성 182명을 대상으로 $IL-1{\alpha}$ 유전자형을 분석하였다. 결 과 : T 대립 유전자는 BMI 감소와 관련이 있었다. BMI $27-30kg/m^2$ 그룹(group III)에서 T 대립유전자의 빈도는 $25kg/m^2$ 미만의 그룹(group I)에 비하여 유의하게 감소하였다 (odds ratio, OR, 0.141; 0.25% CI, 0.04-0.54). 더욱이 태음인 여성에서 $IL-1{\alpha}$ T 대립유전자의 빈도가 normal group에 비하여 overweight group (BMI $27-29kg/m^2$)에서 명확하게 감소하였다 (OR, 0.139; 95% CI, 0.04-0.54). 결 론 : 본 연구에서 175명의 체질분석결과 $BMI{\geq}25$인 군들의 태음인의 빈도가 높았으며, BMI는 CC genotype를 가진 사람에서보다 CT+TT genotype를 가진 사람에게서 더 낮았다. 태음인에서 동형접합 또는 이형접합 T 대립유전자가 $BMI{\geq}25$인 군에서 유의하게 감소하였다. 이상의 결과는 한국 여성에서 $IL-1{\alpha}$ 유전자 조절부위에 위치한 -889C/T 다형성과 비만 및 사상체질의 관련되는 것을 의미한다.

• The Korean Journal of Food And Nutrition
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• v.26 no.4
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• pp.909-918
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• 2013

The objective of this study is to investigate the effects of dietary nutrient intakes for markers of blood glucose and inflammation which is important to the progress of type 2 diabetes and the development of its complications. For this study, 76 adults with diabetes (42 males, 34 females) were recruited from a group of patients who had visited the department of endocrine medicine. Data on anthropometric characteristics, clinical indices such as hemoglobin A1c (HbA1c) and C-reactive protein (CRP), and dietary nutrient intakes were collected. Our results have shown that 66% of subjects were either overweight or obese. Serum analysis indicates that levels of C-peptide, glucose, HbA1c, CRP, triglyceride, LDL-cholesterol were higher than normal range. Results from the dietary nutrient intake survey displayed that intakes of cholesterol and sodium were higher than Dietary Reference Intakes for Koreans. On the contrary, folate intake was lower than the guideline. Within the females, energy contribution from carbohydrate was higher than Korean Diabetes Association guideline. Statistical analysis has revealed a negative correlation between serum HbA1c level and dietary intakes of polyunsaturated fatty acid (PUFA), n-3 PUFA, ${\beta}$-carotene and vitamin E after adjustments for age, BMI, smoking habits, alcohol consumption, exercise and ingestion of diabetes mellitus medication (p<0.05). Serum CRP level was inversely associated with dietary intakes of carbohydrate, protein, vitamin C and fiber (p<0.05). Our results suggest that dietary nutrient intakes may influence the levels of HbA1c and CRP, and subsequently, it may help in the management/treatment of type 2 diabetes.

• Journal of the Korean Society of Clothing and Textiles
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• v.37 no.6
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• pp.799-808
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• 2013

Previous research reported that body size measured as Body Mass Index (BMI) and body shape measured as waist-hip-ratio (WHR) are two essential factors that form the perceptions of body attractiveness. However, the debate on the importance of BMI versus WHR is ongoing. In addition, scholarly articles, that focus on the role of geographic and cultural variability on perceptions of attractiveness, report inconsistent results. Some suggested that according to globalization and the rise of mass media, geographic variability of perceptions of attractiveness have been altered, while others believed that it remains. This study cross-regionally investigates the role of body size and body shape on the perceptions of female attractiveness. Samples were composed of 107 female college students in Alabama and 107 female college students in California. Participants viewed 27 three-dimensional body scan images of women in three body shapes (pear, hourglass, and rectangle) and three body sizes (underweight, normal weight, and overweight) and rated their perceptions of attractiveness. Images were shown to students in a random order with an overhead projector and Microsoft Office PowerPoint software. A three-way mixed-ANOVA was conducted to analyze the data. The results of the study showed that some regional differences exist between the two sample groups. However, regardless of the regional difference, hourglass shapes were perceived to be the most attractive shape and underweight sizes were perceived to be the most attractive size for both samples.

• Journal of Nutrition and Health
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• v.37 no.9
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• pp.809-816
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• 2004

The purpose of this study was to evaluate the effect of maternal nutritional status and health behaviors on the concentrations of minerals (Zn, Fe, Ca) and the immunological substances (lactoferrin, sIgA, Iysozyme) in breast milk. Breast milk was collected from 193 healthy Korean women from obstetric clinics and postpartum care centers in Seoul. : 99 colostrum (1 - 5 days postpartum), 33 transitional milk (6 - 10 days postpartum), 61 mature milk (11 - 50 days postpartum). The concentrations of minerals and immunological substance were highest in colostrum and decreased with lactational period. Concentrations of Zn and Fe reduced significantly from colostrum to mature milk, however, Ca concentration stayed constant throughout the lactational period. Contents of lactoferrin, sIgA, and lysozyme were significantly lower in mature milk than in colostrum. Mother's nutritional status, assessed by prepregnancy BMI, had an effect only on colostrum, but not on transition and mature milk. Fe concentration of colostrum was significantly lower in underweight (prepregnancy BMI < 18.5) than in overweight mothers (prepregnancy BMI $\geq$ 23.0). Also lower tendency was observed for sIgA and lysozyme contents, even though the difference was not statistically significant. Pregnancy weight gain had no effect on the breast milk component. Since nutritional factors had some effect on colostrum, the health behaviors of mothers providing colostrum were assessed. The mother's behavior of smoking, drinking, morning sickness, parity, disease, nutrient supplement use had no significant effect on the breast milk component, however, Zn, sIgA, and lysozyme were the somewhat affected components by maternal health behavior.

• Journal of Korean Medicine for Obesity Research
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• v.7 no.1
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• pp.71-85
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• 2007

Objectives : This study was performed to identify the efficacy and safety of ephedra and green tea mesotherapy on localized fat. Methods : Twenty-five healthy $20{\sim}35$ year overweight women (body mass $index{\geq}23kg/m^2$) were recruited and randomly assigned to two groups : experimental(mahuang and green tea) group (n=13), placebo(Normal saline) group (n=12). Total 8 times of herbarl mesotherapy treatment were performed once per week, 4 times were performed on right thigh (1st period), after wash-out for 1 week, the other 4 times were performed on left thigh (2nd period) without any modification of diet or exercise. Body composition, thigh circumferences were measured at each period before and after the intervention. Subcutaneous fat was measured by CT scan at before and after the 1st period of intervention and free fatty acid(FFA) was measured immediately before 1st intervention, 1 hour later, 24 hours later, and 7 days later. Satisfaction score and adverse events were evaluated. Results : In the subcutaneous fat, there were no significances, but in the circumferences. Experimental group had significant change when compared with placebo group (p<0.05). In FFA, experimental group has significant elevation at after 1 hour (p<0.05) evaluation. There were no serious adverse events in both groups. Conclusions : Experimental group had some significant findings in circumference, FFA, and had no serious adverse events comparing with placebo group, and no serious adverse events have been reported in both group. Mesotherapy with herb have a possibility of treating localized fat

• Journal of the Korean Society of Clothing and Textiles
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• v.33 no.2
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• pp.230-243
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• 2009

The purpose of this study was to analyse the body sizes of $7{\sim}12$ years elementary school girls and also to categorize KS size dimensions by the detailed information of ages and body shapes. For the study, the data of SizeKorea(2004) was analysed. Height, bust, waist, hip, the ratio of waist to height and hip to height were significant between age groups, but the ratio of bust to height was not. Therefore, the increase of bust size was resulted in growth of bust circumference, instead of bust volume. In the same height group, over 11 year girls had smaller waist, while over 12 year girls had bigger hip. For Grouping girls by ages and body shapes, the ages were divided into 2 groups, under 10 years old and 11 to 12 years old. The body shapes classified into 3 groups 'Stout-shape', 'Middle-shape', and 'slim-shape', by the ratios of bust to height and hip to height. 'Stout-shape' was significantly big at the almost sizes, but 'Middle-shape' was significantly big at only circumferences, not lengths. In addition, drop(the difference between bust and hip) and lower-drop(the difference between waist and hip) were in inverse proportion to the ratios of bust to height and hip to height. It meant the increases of bust-ratio and hip-ratio of 'Stout-shape' were resulted in overweight, rather than female matureness. The distribution of sizes over 0.5% were grouped for grading system and the subtotal percentiles of each group were calculated for industrial data. The groups which covered more than 10% of consumers were 2 to 6 and the 1 or 2 groups for 'Stout-shape' were also observed, so that children's ready-to wear companies could use them efficiently for their own consumer target.

• Korean Journal of Community Nutrition
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• v.24 no.2
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• pp.117-126
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• 2019

Objectives: This study was conducted to investigate the current difficulties surrounding children's obesity management and evaluate the application of a mobile phone as a tool to overcome such difficulties of obesity management from the perspective of main caregivers of elementary school students. Methods: The qualitative data were collected through 3 focus group interviews including 6 full-time housewives, 7 mothers with overweight children, and 4 working mothers. Data were analyzed using a thematic approach. Results: The limitations of current children's obesity management included difficulty in diet management and exercise as well as challenges of setting goals and lack of support at the household and school levels. Mobile technology may be useful to overcome the current problems by providing real-time knowledge on diet management and physical activity, online compensation scheme according to goal setting, and interactive environmental supports at both household and school levels for promoting overall health. Conclusions: The mobile-based multiple support program may assist in overcoming the current limitations of child obesity management by providing tailored information and by creating a more supportive environment.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.21 no.3
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• pp.288-297
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• 1999

This study has been carried out in order to measure the thickness of soft-tissue on lateral cephalographs based on body mass index(BMI) and the change in soft-tissue thickness after surgical correction of mandibular protrusion. The control material in cephalometric study comprised students at The Dental College, 38 persons, aged 21~24 years and the patient material comprised 20 women and 12men, aged 19~28 years with mandibular protrusion.The thickness of the soft-tissue based on BMI in control and study groups, the comparison between them, immediate postoperative change in the thickness, 6 months after surgery, ratio of soft-tissue response and correlation was established through various statistical methods. The result were as follows : 1. The groups based on BMI showed significant differences each other as regards the linear measurements. The thickest soft-tissue was measured 13.6mm, 15.47mm, 16.76mm at Ss, the thinnest at G' 6.0mm, 6.7mm, 7.26mm respectively. 2. The differences between control and experimental groups based on BMI showed to be significant. There were no differences at G'. The soft-tissue in prognathic patients was thicker at Ss, Ls and thinner at Li, Ls, Pg', Gn', Me'. Differential gap was greater in overweight groups. 3. The immediate soft-tissue change after surgery showed the increase at Li, Ls, Pg', Gn', Me' except G', Ls in all groups. 4. The postoperative soft-tissue change 6 months after surgery was similar with immediate change. The soft-tissue shows the increase in the thickness at Li, Pg', Gn', Me' and the greatest difference occurred at Li, 1.1mm, 0.98mm, 1.2mm respectively. 5. The patients with lower BMI index showed higher soft-tissue response to bony movement at Pg'. The immediate response ratio was 91%, 87%, 81% in A,B,C groups respectively, the response 6 months after surgery showed 96%, 91%, 84%.