• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6269-6273
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• 2014

Growing evidence suggests that miR-150-5p has an important role in regulating genesis of various types of cancer. However, the roles and the underlying mechanisms of miR-150-5p in development of colorectal cancer (CRC) remain largely unknown. Transwell chambers were used to analyze effects on cell migration and invasion by miR-150-5p. Quantitative real-time PCR (qRT-PCR), Western blotting and dual-luciferase 3' UTR reporter assay were carried out to identify the target genes of miR-150-5p. In our research, miR-150-5p suppressed CRC cell migration and invasion, and MUC4 was identified as a direct target gene. Its effects were partly blocked by re-expression of MUC4. In conclusiomn, miR-150-5p may suppress CRC metastasis through directly targeting MUC4, highlighting its potential as a novel agent for the treatment of CRC metastasis.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2017년도 춘계 학술논문 발표대회
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• pp.246-247
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• 2017

In this study, it reviewed the effect of moisture migration in concrete with heating rate on concrete spalling. Concrete specimens with compressive strength 30MPa and 110MPa are used and its size is □100×100×h200mm. And, two kinds of heating rate are set such as IS0 834 and 1℃/min. As a result, in the concrete specimen exposed to ISO 834 standard heating condition, moisture could migrate through pore network and surface concrete pieces fall out by generating moisture clog near the surface in 110MPa concrete specimen. Meanwhile, In the case of concrete specimens exposed to 1℃/min. heating condition, it is appeared that moisture could not migrate because temperature is distributed uniformly. Therefore, surface spalling is not occurred with low heating rate. However, in the case of 110MPa concrete specimen is exploded even though it heated by low heating rate.

• 한국가시화정보학회:학술대회논문집
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• 한국가시화정보학회 2004년도 Proceedings of 2004 Korea-Japan Joint Seminar on Particle Image Velocimetry
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• pp.119-124
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• 2004

Experimental study was conducted to characterize the flow effect of particle migration in a microchannel which can be used to deliver small amount of liquids, drugs, biological agents and particles in microfluidic devices. Fluorescent particles of $1\{mu}m$ diameter were used to obtain velocity profiles of the fluid in which large particles of $10\{mu}m$ diameter were suspended at different volume fraction of 0.6 and $0.8\%$. Measurements were obtained by using micro-PIV system which contains a Nd:YAG laser with a light of 532-nm wavelength, an inverted epi-fluorescent microscope and a cooled CCD camera to record particle images. The volume fraction of $\phi$ and the particle Reynolds number $Re_p$Rep were used as a parameter to assess the influence of the velocity profile of the suspensions. To expect the slip velocity between the particle and fluids, experiments were carried out at low volume fraction. It was shown that the velocity profile was not influenced by Rep but influenced by the volume fraction, which is in similar trend with the previous study.

• 한국해양학회지
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• 제10권1호
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• pp.1-6
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• 1975

A marine geological investigation of the glass sand deposit in the beach along the west coast of Ahnmyeon Island, South Chung Cheong Province, Korea was carried out to solve the problen of sand material migration, textural properties of the sands and the glass sand reserve for future exploitation. Several bos coring analyses by means of the internal sedimentary structure.i.e., cross- stratification show significantly that most sands are moving and accumulation along the mean vector direction of $N20^{\circ}E-N60^{\circ}$ E in the area investigated. The average mean size of the sand sediments in the area studied ranges from 0.212mm to 0.275mm. The mechanism of sand migration in the area is considered to be interplay between longshore drift and flood tidal current. The sorting value of the sands ranges from 0.24 to 0.50. Therefore, these sand sediments are characteristic to be "well sorted". The average chemical composition of the glass sand in the area is the following: $SiO\_2$:-90.8%, $Al_2O_3$: -2.18%, $Fe_2O_3$:-0.73%, CaO:-1.79. The binocular microscope examination of the sands show that most of the sands are characteristically ice- clear quartz in mineral composition and their count percentage is mostly 92% or 96%.

• Bulletin of the Korean Chemical Society
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• 제10권1호
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• pp.60-66
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• 1989

Semiempirical computations using the AM1 and MNDO methods were carried out in order to elucidate allowed mechanisms for 1,3-group(X) rearrangement processes with X = $BH_2$, $CH_3$, CN, F, $NH_2$, OH, Cl and SH. The reactivity of the group migration was largely controlled by the steric effect in the 4-membered ring transition state, an antarafacial process having a greater energy barrier due to a greater steric repulsion. For the groups with lone pair electrons, the participation of the lone pair orbital is found to ease the steric effect by enabling the FMO interation with highly polarizable, high lying, lone pair electrons at relatively distant range; the involvement of lone pairs in the transition state causes an alteration of the symmetry selection rule to that of a 6-electron system with an allowed 1,3-suprafacial migration in contrast to an allowed 1,3-antarafacial migration for a 4-electron system. Various stereoelectronic aspects were analysed in some detail.

• 한국인구학
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• 제11권1호
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• pp.117-130
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• 1988

Though most of East European coutries seem to hold a pronatalist policy, they approve of family planning and provide contraceptive services. One of the most popular contraceptive method has traditionally been the coitus interruptus in these countries. One of the major reasons for adopting family planning is to decrease the incidence of induced abortion has been closely related to the popular use of coitus interruptus in these countries. Most of the East European countries liberalized induce abortion legally mainly to neutralize the wide practice of illegal abortion. However, the practice of induced abortion is under the strict control of the public health authorities in these countries. Migration and redistribution of population of population are mostly under the control of the state in these socialist countries. Policies on migration and redistribution are usually carried out to achieve the general goal of socio-economic development plan of the states. Both incentive measures and control measures are mobilized to affect the internal migration and redistribution of population. With respect to public health East European countries are characterized by the socialized medicine following the Soviet model. Public health measures and medical practice are controlled by the state and highly centralized in many countries except Yugoslavia. They place much emphasis on preventive medicine, primary health care, occupatinal and industrial medicine, and health education. Private sectors in medical practice do not exist in these countries of Eastern Europe.

• 대한의생명과학회지
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• 제25권2호
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• pp.149-158
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• 2019

The objective of this study was to evaluate the effects of thoracic mobilization (TM) on the angle of thoracic kyphosis, and static and dynamic balances by application period. The subjects of this study were 18 adult males and females (${\geq}20years\; old$) who had the angle of thoracic kyphosis equal to or higher than $40^{\circ}$. A pre-test was conducted for all subjects and TM was carried out. Data were collected before the intervention, 3 weeks after the intervention, and 6 weeks after the intervention. It was measured three times per measurement and mean values were used for the analysis. The results of this study showed that the angle of thoracic kyphosis significantly (P<.05) decreased after applying TM. However, the migration area ($mm^2$) of the center of pressure (COP) in the static balance did not vary significantly. In the case of the dynamic balance, when eyes were open, the migration area ($mm^2$) of the COP significantly (P<.05) decreased after 3 weeks. When eyes were open, the migration area ($mm^2$) of the COP significantly (P<.05) decreased after 3 weeks and 6 weeks. Therefore, an intervention for improving the human body alignment and balance should be applied for a long-term, rather than a short-term, in order to be effective.

• 대한수의학회지
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• 제60권4호
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• pp.203-207
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• 2020

This study presents neuronal migration pattern of dopamine (DA) neurons generated in separate regions occupying the ventral mesencephalic territory. A single pulse 5-bromodeoxyuridine (BrdU) was administered at embryonic day (E)10-E15. Distribution of tyrosine hydroxylase (TH) positive cells was determined at E13-postnatal day 0 (P0) by immunohistochemistry. BrdU positive cells labeled at E10 were spread out uniformly in the mesencephalon from E13 to E15, migrating through dorsal and ventral routes at E17 and P0. TH expression labeled at E10 was observed at E13 in the ventromedial region and clearly formed in the ventral tegmental area (VTA) at E15. At E17, TH expression in the substantia nigra (SN) was observed in the ventrolateral region, spreading more outward of the mesencephalon at P0. Generation of TH-positive cells labeled at E13 was also observed in VTA and SN of the mesencephalon at E17 and P0. The expression of these cells labeled after E15 was markedly decreased. These results demonstrated that an almost complete primary structure of DA neuron was formed at the early embryonic stage in the ventral mesencephalon, showing the most active neuronal migration was occurred at E13-E17.

• Journal of Radiation Protection and Research
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• 제8권2호
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• pp.15-35
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• 1983

특별히 제작한 영동장치를 써서 고전압 전기영동법에 의하여 24시간 중성자 조사하고 150일 냉각한 90% 농축질산우라닐 수용액의 핵분열 생성물을 분리하였다. 핵분열생성물부터 Zr-95, Nb-95의 분리는 0.1M-$HClO_4$(pH=0.85), 0.05M-HCl+0.09M-KCl(pH=0.9), 0.1M-HCl(pH=1.1), 0.01M-HCl(pH=2.0)의 이동조건에서 가능하며 Zr-95, Nb-95는 원점부터 +1cm의 거리에서 분리된다. Zr-95와 Nb-95의 상호분리는 2% 수산암모늄을 첨가하는 경우 가능하다. 즉 0.1M-$HClO_4$, 0.05M-HCl+0.09M-KCl, 0.1M-HCl, 0.1M-식초산+0.1M- 식초산나트륨(pH=4.68)의 이동조건에서 원점부터 $-6{\sim}-7cm$ 거리에서 Nb-95, $+1{\sim}-1cm$ 거리에서 Zr-95가 각각 분리된다. 핵분열생성물부터 Ru-103의 분리는 0.025M-$Na_2CO_3+0.025M-NaHCO_3(pH=10.0)$, $0.01M-Na_3PO_4(pH=11.7)$, 0.1M-NaOH(pH=13.2)의 이동조건에서 가능하며 Ru-103는 각각 원점부터 -6cm, -4cm, -3cm거리 이동한다.

• Current Research on Agriculture and Life Sciences
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• 제16권
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• pp.15-23
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• 1998

본 실험에서는 수리구조물의 보호되는 토립자의 필터내 이동과 이로인한 필터의 기능 저하를 실험을 통하여 비교분석한 결과 다음과 같은 결론을 얻었다. 1. 수두가 높고 공극이 클수록 필터내 세사의 이동은 심했으며 조기에 흐름의 안정화에 도달하게 되었지만 필터외부로의 입자유출도 많았으며, 공극이 작고 유속이 빠르면 필터와 모래의 접촉면에 인접한 곳에서 Blocking현상이 크게 일어남을 알 수 있었다. 2. 필터기능에 영향을 주는 세사의 이동은 공극의 크기와 수두에 큰 영향을 받음을 알 수 있었고, USCE 필터와 USSPL 필터는 공극이 크기 때문에 같은 조건하에서 흐름의 안정이 다른 필터들 보다 조기에 이루어 졌다. 3. 세사의 이동잔류량은 USSPL, USCE, USBR, Newton & Hurley, Bertram 필터순으로 많이 나타났다. 4. 흐름의 안전에 소요된 시간은 Bertram, Newton & Hurley, USBR, USSPL, USCE 필터순으로 적었고, 투수계수는 USBR, Bertram, Newton & Hurley, USSPL, USCE 필터순으로 크게 나타났다. 5. 여러 가지 종류의 필터기준중 USCE와 USSPL기준의 필터가 투수계수의 안정에 소요된 시간이 가장 짧고, 세사의 이동량이 적으므로 가장 적합한 것으로 인정된다.