• The Korean Journal of Physiology and Pharmacology
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• v.13 no.2
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• pp.107-113
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• 2009

Olibanum (Boswellia serrata) has been shown to have anti-inflammatory, anti-arthritic and anticancer effects. This study determined the role of a water extract of olibanum in platelet-derived growth factor (PDGF)-stimulated proliferation and migration of rat aortic smooth muscle cells (RASMCs). PDGF-BB induced the migration and proliferation of RASMCs that were inhibited by olibanum extract in a dose-dependent manner. The PDGF-BB-increased phosphorylation of p38 mitogen-activated protein kinase (MAPK); the heat shock protein (Hsp) 27 was significantly inhibited by the olibanum extract. The effects of PDGF-BB-induced extracellular signal-regulated kinase1/2 was not altered by the olibanum extract. Treatment with olibanum extract inhibited PDGF-BB-stimulated sprout out growth of aortic rings. These results suggest that the water extract of olibanum inhibits PDGF-BB-stimulated migration and proliferation in RASMCs as well as sprout out growth, which may be mediated by the inhibition of the p38 MAPK and Hsp27 pathways.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.9
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• pp.4165-4187
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• 2016

As an emerging technology, cloud computing is a revolution in information technology that attracts significant attention from both public and private sectors. In this paper, we proposed a dynamic approach for live migration to obviate overloaded machines. This approach is applied on OpenStack, which rapidly grows in an open source cloud computing platform. We conducted a cost-aware dynamic live migration for virtual machines (VMs) at an appropriate time to obviate the violation of service level agreement (SLA) before it happens. We conducted a preemptive migration to offload physical machine (PM) before the overload situation depending on the predictive method. We have carried out a distributed model, a predictive method, and a dynamic threshold policy, which are efficient for the scalable environment as cloud computing. Experimental results have indicated that our model succeeded in avoiding the overload at a suitable time. The simulation results from our solution remarked the very efficient reduction of VM migrations and SLA violation, which could help cloud providers to deliver a good quality of service (QoS).

• Korean Journal of Plant Resources
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• v.21 no.1
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• pp.96-102
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• 2008

Nelumbo nucifera Gaertn.(family Nymphaeaceae) has been used for summer heat syndrome as home remedy in Japan, China and Korea. Although whole plant parts are edible, root is commonly consumed. It has been reported that rhizome extract showed anti-diabetic and anti-inflammatory effects. However, in spite of usefulness for treatment of various diseases, the effect of Nelumbo nucifera rhizome(NNR) on proliferation, migration and matrix degrading enzymes-matrix metalloproteinsases(MMPs), the expression of which degrades extracellular matrix(ECM) leading to metastasis, has not been fully elucidated. We examined the effect of hot water extract of NNR on the proliferation, migration and secretion of MMP-2 and MMP-9 in rat smooth muscle cells(rSMC), epidermoid cancer cells(A431) and breast cancer cells(MDA-MB-231). The proliferation assay was carried out using MTT assay, the principle of which depends upon the conversion of MTT by mitochondrial dehydrogensases of viable cells to formazan crystals. The effect of NNR on migration of cells was examined using wound healing assay. Our results showed that there was inhibition in the proliferation, migration and expression of MMP-2 and MMP-9 in dose dependent fashion in all the cells used. Thus, we concluded that NNR could be used as traditional medicine in the treatment of various diseases where proliferation, migration and MMPs' expression plays a pathological role like in restenosis and metastasis.

• The Korean Journal of Pain
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• v.10 no.1
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• pp.64-68
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• 1997

Background : Patients mover more as their post operative pain decrease. With the increase in movement there will be a tendency for the epidural catheter to migrate out of its original position. We studied 2 methods of fixation of the epidural catheter and the changes in position as related to patient movement. Methods : Patients were divided into two groups. Patients in Group A had their epidural catheter formed with a circular loop at the (skin) exit site then directed over the right shoulder. Group B had the epidural catheter flxed with Fixomull on the exit site without forming a circular loop. At the end of the operation, 3 mg of epidural morphine was injected via indwelling epidural catheter for postoperative pain control. Epidural catheter depth was measured 24 hours later. Results : The overall rate of migration of epidural catheter was 61.9%. In Group A, number of patients whose catheter migrated over 0.5 cm was 23(69.9%) with 14 inward migration and 9 outward migration. Group B had 16(53%) patients catheters migrate over 0.5 cm, with 2 patients having inward migration and 14 outward migration. Conclusions : Although the rates of migration of epidural catheter were similar for both groups, the number of inner migration of catheter, which could result serious complications, was significantly lower in Group B than Group A. Based on our results we recommend the epidural catheter be fixed without a circular loop.

• Journal of Ginseng Research
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• v.47 no.1
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• pp.89-96
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• 2023

Background and aim: Panax ginseng, a key herbal medicine of replenishing Qi and tonifying Spleen, is widely used in the treatment of gastrointestinal diseases in East Asia. In this study, we aim to investigate the potential effects and mechanisms of polysaccharides from P. ginseng (PGP) on intestinal mucosal restitution which is one of the crucial repair modalities during the recovery of mucosal injury controlled by the Ca²⁺ signaling. Methods: Rat model of intestinal mucosal injury was induced by indomethacin. The fractional cell migration was carried out by immunohistochemistry staining with BrdU. The morphological observations on intestinal mucosal injury were also performed. Intestinal epithelial cell (IEC-6) migration in vitro was conducted by scratch method. Western-blot was adopted to determine the expressions of PLC-𝛾1, Rac1, TRPC1, RhoA and Cav-1. Immunoprecipitation was used to evaluate the levels of Rac1/PLC-𝛾1, RhoA/TRPC1 and Cav-1/TRPC1. Results: The results showed that PGP effectively reduced the assessment of intestinal mucosal injury, reversed the inhibition of epithelial cell migration induced by Indomethacin, and increased the level of Ca²⁺ in intestinal mucosa in vivo. Moreover, PGP dramatically promoted IEC-6 cell migration, the expression of Ca²⁺ regulators (PLC-𝛾1, Rac1, TRPC1, Cav-1 and RhoA) as well as protein complexes (Rac1/PLC-𝛾1, Cav-1/TRPC1 and RhoA/TRPC1) in vitro. Conclusion: PGP increases the Ca²⁺ content in intestinal mucosa partly through controlling the regulators of Ca²⁺ mobilization, subsequently promotes intestinal epithelial cell migration, and then prevents intestinal mucosal injury induced by indomethacin.

• Journal of environmental and Sanitary engineering
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• v.13 no.3
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• pp.43-51
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• 1998

This study presents a numerical method for calculating gas flow around a sanitary landfill gas vent, when gas flows by pressure. The method described is a three-dimensional compartmental model and includes methods to determine the dimensions for the model. Using the numerical method, controll of press and gases flowing out to the air through final cover soil, and degine of sanitary landfill gas vents.

• The Korean Journal of Quaternary Research
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• v.7 no.1
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• pp.93-101
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• 1993

A sedimentation study of the Cheonripo intertidal beach sands and its related coastal dune sands, Cheonripo, Seosan Gun, Choongcheong Namdo, Korea has been carried out based on a series of several summer time field surveys. Each subenvironment in the Cheonripo coastal zone, that is, intertidal sand beach and coastal sand dune, could be differenciated in terms of textural parameters. The coastal dune sands are finer than the intertidal beach sands in mean grain size, and the sorting of dune sands is relatively poorer than that of intertidal beach sands. However, the skewness of intertidal beach and dune sands is commonly positive. Such textural parameters are characteristically differentiated on scatter diagrams. A series of megaripple bedform observations for 6 tidal cycle periods(August 13, 14 and 15, 1990) are interpreted to find out migration pattern of bedforms and its related sand migration. Such migration natures are shown on the tables and figures.

• Journal of Information Processing Systems
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• v.14 no.6
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• pp.1480-1493
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• 2018

Recently, computational intelligence has received a lot of attention from researchers due to its potential applications to artificial intelligence. In computer science, computational intelligence refers to a machine's ability to learn how to compete various tasks, such as making observations or carrying out experiments. We adopted a computational intelligence solution to monitoring residual resources in cloud computing environments. The proposed residual resource monitoring scheme periodically monitors the cloud-based host machines, so that the post migration performance of a virtual machine is as consistent with the pre-migration performance as possible. To this end, we use a novel similarity measure to find the best target host to migrate a virtual machine to. The design of the proposed residual resource monitoring scheme helps maintain the quality of service and service level agreement during the migration. We carried out a number of experimental evaluations to demonstrate the effectiveness of the proposed residual resource monitoring scheme. Our results show that the proposed scheme intelligently measures the similarities between virtual machines in cloud computing environments without causing performance degradation, whilst preserving the quality of service and service level agreement.

• Korea journal of population studies
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• v.23 no.2
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• pp.39-77
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• 2000

The paper examines non-agricultural occupations of Korean immigrants in the Russian Far East from 1860s to 1930s. First of all, theoretical perspectives regarding immigrants\` job selection and positions in the labor market such as cultural theory, segmented labor market theory, human capital theory, and ethnic enclave theory were reviewed and then how these theories can be applied to various jobs of Korean immigrants including mining, fishing, small business, service, and miscellaneous jobs was studied. Next. this article points out that those theories cannot explain both supply and demand sides of migration simultaneously, suggesting the need to integrate two sides of migration. In order to fill out this gap in the literature, this paper suggests the integrative approach which combines supply side and demand side of migration. According to this model, several factors in the non-agricultural jabs which were affecting Korean immigration in the Russian Far East. were identified and discussed in relation with existing theoretical perspectives. Finally this paper concludes that, in order to understand Koran migration in the Russian Far East properly, we have to take into consideration simultaneously both supply-sided factors of immigration including farming-oriented characteristics of Koreans, Korean socio-economic problems preceding immigration, and self-dependent tendencies of Korean immigrants and demand-side factor like the Russian migration policy to the immigrants and various regional situations in the Russian Far East.

• Journal of Korean Society of Rural Planning
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• v.30 no.1
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• pp.33-42
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• 2024

The purpose of this study is to investigate the possible relationship between population migration and population inequality in rural areas. This study conducted a case study on the eup·myeon(rural)areas in Chungcheongbuk-do. First, the population migration was divided into four patterns, and the characteristics of population migration in rural areas were analyzed based on the net migration. The analysis results showed that there was serious migration between rural areas, and the population in rural areas mainly moved out to urban areas within the province, but the urban population outside the province moved out to rural areas. The main areas of population inflows included areas such as Deoksan-eup, Jincheon-gun, Osong-eup and Ochang-eup, Cheongju-si. Second, the Theil index was used to quantitatively analyze the level of population inequality between rural areas. The Theil index of the population aged 0~14 increased from 0.38 to 0.53, that of population aged 15-64 increased from 0.22 to 0.30, and that of population aged over 65 increased from 0.07 to 0.09, indicating an increase in population inequality. Finally, due to the continued large-scale inflows of population into Osong-eup and Ochang-eup, the Theil index of total population in Cheongju-si increased from 0.13 in 2009 to 0.23 in 2020, which meant that the level of population inequality had increased. Similarly, due to the continued large population inflows into Deoksan-eup, the Theil index of total population in Jincheon-gun increased from 0.14 in 2009 to 0.18 in 2020, which meant that the level of population inequality had increased. In conclusion, large-scale population inflows into specific areas will lead to an increase in the level of population inequality.