• 고신대학교 의과대학 학술지
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• 제33권2호
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• pp.200-207
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• 2018

Tracheobronchopathia osteoplastica (TO) is a rare benign disease in which the anterior inner wall of the tracheobronchus changes because of abnormal chondrogenesis or ossification, while the posterior wall of the trachea is spared. The etiology is not clearly understood, but may relate with chronic infection, inflammation, and trauma. In some case studies, it has also been reported to be accompanied by other chronic diseases such as atrophic rhinitis and amyloidosis. However, Coexistence of TO and tuberculosis has rarely been reported, and has never been reported in Korea. Here, we report a case of a 70-year-old male patient who complained of hemoptysis and whose case was diagnosed as TO and pulmonary tuberculosis through bronchoscopy with bronchial washing and biopsy.

• Journal of Korean Neurosurgical Society
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• 제59권6호
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• pp.604-609
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• 2016

Objective : The aim of this study was to compare the clinical and radiological outcomes associated with the use of hydroxyapatite (HA) spacer and allogeneic bone (AB) spacer in laminoplasty. Methods : From January 2006 to July 2014, 79 patients with cervical spondylotic myelopathy or ossification of the posterior longitudinal ligament underwent cervical laminoplasty. The radiologic parameters were obtained from plain radiography and three-dimensional computed tomography. All images were taken before and after surgery. Cervical lordosis, spinal canal dimension, fusion between lamina and spacer, and resorption of spacer were checked. Clinical outcomes were assessed using visual analog scale and Japanese Orthopedic Association. Results : Double-door laminoplasty was performed on 280 levels : 182 in the HA group and 98 in the AB group. The mean follow-up was 23.1 months (range : 4-69 months). Similar fusion rates were found in these groups (p=0.3). The resorption rate between lamina and spacer was lower in the HA group (p<0.001). During the immediate postoperative period, the canal dimension of both groups increased compared with the results in the preoperative period. However, the canal dimension of the AB group decreased over time compared with that of the HA group (p<0.001). Conclusion : Double-door laminoplasty improved the clinical outcomes of both groups. However, the spinal canal dimension in the AB group showed a greater degree of reduction than in the HA group at the final postoperative follow-up. Therefore, we suggest that surgeons consider the use of larger-sized AB spacers in double-door laminoplasties.

• 대한영상의학회지
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• 제85권3호
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• pp.488-504
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• 2024

정상 변이란 일반적으로 무증상이며 우연히 발견되는 영상 소견을 의미하며, 병적 상태와 유사한 소견을 보일 수 있다. 소아 뼈의 정상 변이를 인지하기 위해서는 장관 골 및 이차 골화 중심의 발달 과정에 대한 이해가 필요하다. 정상 변이의 다양한 영상의학적 소견에 익숙해진다면 불필요한 추가 영상 검사 및 잘못된 진단과 치료를 방지할 수 있다. 본 종설에서는 성장하는 소아의 뼈에서 보이는 정상 변이들의 특징적인 영상 소견과 이를 병적 상태와 구별하기 위한 방법들에 대해서 논의하고자 한다.

• 한국어류학회지
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• 제27권3호
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• pp.189-198
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• 2015

본 연구는 능성어 자치어의 골격발달을 관찰하여 분류학적 연구의 기초자료로 이용하고자 실시하였다. 자치어는 전남 여수시 거문도에 위치한 해상가두리에서 사육하던 어미로부터 채란하여 사육한 것을 대상으로 관찰하였다. 자치어의 사육 수온범위는 $21.5{\sim}24.5^{\circ}C$ (평균 $23.0{\pm}1.5^{\circ}C$)였다. 부화 직후의 난황을 가진 자어는 골화가 전혀 이루어지지 않았고, 평균 전장 2.66 mm에 달하면 윗턱을 구성하는 전상악골과 주상악골이 골화되었고, 아래턱을 구성하는 치골이 골화하였으며, 두개골의 기저를 형성하는 부설골이 골화하였다. 새개부를 형성하는 전새개골과 주새개골의 골화가 시작되었다. 꼬리지느러미를 지지하는 미골은 추골과 골편으로 이루어진 미골복합체로 구성된다. 평균 전장 2.59 mm까지는 전혀 골화가 일어나지 않았고, 미부봉상골이 $45^{\circ}$로 휘어져 있다. 담기골의 골화는 평균 전장 6.12 mm에 첫 번째 혈관간극이 뒷지느러미 2개의 가시와 관절되어 가장 먼저 골화가 시작되고, 신경간극 또한 등 지느러미 2개의 가시와 관절되어 골화하기 시작하였으며, 혈관간극과 신경간극은 평균 전장 21.9 mm에 골화가 완료되는 개체가 출현하였다.

• 대한수의학회지
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• 제37권2호
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• pp.269-280
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• 1997

The development and change of the cartilage canals ralated to chondrocyte growth and the major histological pattern were investigated in the calcaneus of the Korean native cattle fetuses from CRL 28mm to 175mm. The results as follows; 1. The cartilage canal first appeared in the caudal subperichondral region of the sustentaculum tali of the CRL 28mm fetus, and well developed after the period. 2. The three major cartilage canals, one entered from the head of calcaneous into where achilles tendon insert and the others from the caudal region of sustentaculum tali and the calcaneal sulcus, growth distinctively. The latters participated in the ossification center prior to the former. 3. The number of cells in this canals and the size increased synchronously with chondrocytic hypertrophy. In the intermediate and deep canals, the chondrogenic change showed distinctinvely. Our results demonstrated that the cartilage canals from the lower part were important the formation of the ossification center, and the growth and development of canals associated with the hypertropic changes of chondrocytes in the calcaneus of the Korean native cattle fetus.

• 한국발생생물학회지:발생과생식
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• 제22권1호
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• pp.9-18
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• 2018

This study was conducted to investigate the skeletal development of bullhead torrent catfish, Liobagrus obesus larvae and to utilize them as basic data for the taxonomic study of Liobagrus larvae. Skeletal development was observed by being divided into cranium, visceral skeleton, shoulder girdle bone, pelvic girdle bone and vertebra. On the first day after hatching, the pre-larvae had an average total length of 7.92 mm, and a line-shaped parasphenoid ossified in the cranium. In the jaw bone, the dentary supporting the lower jaw and the maxillary supporting the upper jaw were ossified. In the anterior abdominal vertebrae of the vertebra, seven centrums began to ossify and five neural spines ossified simultaneously. On the 3 day after hatching, pre-larvae had an average total length of 8.95 mm, and the prefrontal ossified in cranium. The number of abdominal vertebrae was increased to 14, and three parapophysis developed from the front side. On the 24th day after hatching, post-larvae had an average total length of 15.2 mm and the epural bone ossified in coccyx. The parhypural bone was ossified, and ossification of coccyx and pelvic girdle bone was completed. On the 30th day after hatching, the average total length of the juvenile was 17.8 mm, and the ossification of cranium and visceral skeleton was all completed while the preorbital and three suborbitals were ossified in the orbital region of the cranium.

• Journal of Korean Neurosurgical Society
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• 제51권2호
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• pp.105-108
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• 2012

Giant spinal schwannoma of the cauda equine involving many nerve roots is rare, and ossification is usually not observed in the schwannoma. A 21-year-old man presented with a 12-month history of urinary dysfunction and numbness below the buttocks. Plain radiography showed scalloping of the posterior surface of the vertebral bodies from L4 to the sacrum, and magnetic resonance imaging and computed tomography revealed a giant cauda equina tumor with dystrophic calcification. The tumor was completely removed, with intraoperative neurophysiologic monitoring. Histopathologic examination showed that the tumor was a schwannoma. The patient's postoperative course was uneventful, with urinary function and numbness gradually improving. Although a giant schwannoma accompanied by dystrophic calcification is extremely rare, such a tumor can be removed safely and completely by meticulous dissection and careful neuromonitoring of the cauda equina spinal nerves involved in the tumor.

• 대한후두음성언어의학회지
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• 제29권1호
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• pp.47-50
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• 2018

Trauma, congenital malformation and aging process can be a cause of the deviation of laryngeal prominence in the thyroid cartilage. Among these, the senility is the most common cause. Usually, ossification in the thyroid cartilage has occurred symmetrically, but the asymmetrical event leads to the shift of laryngeal prominence. Also, such deformity can provoke protrusion of false vocal fold. A 75-year-old man with hoarseness and globus sense in throat visited our clinic. Five years ago, he experienced a blunt trauma on left midline neck and had a concave deformity in the left thyroid cartilage lamina. Laryngoscopic findings revealed a marked protrusion in the left false vocal fold. We performed the laryngeal microsurgery to discriminate the tumorous condition. The pathology revealed non-pathologic mucosa. We report a unique and didactic case with a brief literature review.

• 한국발생생물학회지:발생과생식
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• 제24권2호
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• pp.125-133
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• 2020

This study is intended to be used as the basic material for the taxonomic research by observing the stages of skeletal development of Luciogobius grandis larvae compared to the skeletal development patterns of the same fish family of Gobiidae. 3 days after hatching (DAH), the preflexion larvae was 4.01±0.11 mm (n=5) in average total length (TL) and the frontal began to ossify in the skull. 17 DAH, the advanced postflexion larvae was 5.37±0.05 mm (n=5) in average TL the supraoccipital and epiotic were ossified in the cranial bone. 36 DAH, the juvenile was 12.2±0.20 mm (n=5) in average TL and the urohyal was ossified in the hyoid arch. In addition to one hypural bone being ossified, the first, second, third and fourth were combined and were made three bone fragments and then, the bone ossification of all skeletons was completed.

• Journal of Veterinary Science
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• 제24권5호
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• pp.64.1-64.6
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• 2023

Two Domestic Korean Shorthair cats presented with dyschezia and vomiting. Computed tomography revealed a colonic mass with calcification and lymph node metastasis in case 1, and a small intestinal mass with disseminated mesenteric metastasis and calcification in case 2. Histopathology revealed intestinal adenocarcinoma with osseous metaplasia. Case 1 died two months after surgery from distant metastasis; and case 2 showed no metastasis for five months but presented with anorexia, euthanized seven months after diagnosis. Metastatic intestinal adenocarcinoma with bone formation should be considered as differential diagnosis for calcification on imaging, and lymph node metastasis at diagnosis may indicate poor prognosis.