• 대한한방내과학회지
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• 제27권4호
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• pp.1027-1034
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• 2006

Objectives: This study was to examine diagnosis of dyskinesia by criteria of oriental medicine and to evaluate the effect of oriental medical treatment on the symptoms. Methods: After the patient was treated with Yonggyedeunggyo-tang, the changes in dyskinetic symptoms were evaluated for treatment efficacy every hospital day. Results: The dyskinesia symptoms disappeared. Conclusions: Herbal medicine and Saam Acupuncture therapy is useful for the treatment of Hemiballism- Hemichorea-Orofacial dyskinesia patients.

• Journal of Oral Medicine and Pain
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• 제45권2호
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• pp.29-33
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• 2020

Tardive dyskinesia (TD) is continuous, repetitive movement disorder of tongue, lip or jaw, induced by medication. It causes pain and dysfunction of oral structures but also interferes with dental treatment and overall social life of patients. As a dentist, it is imperative to recognize and manage TD, although currently, there is no definitive treatment for TD. This article reports a patient with TD of tongue, successfully managed with an oral appliance mimicking sensory tricks. Considering the limited treatment options for TD, an oral appliance, a simple and conservative approach, can be a meaningful treatment for some patients with orofacial dyskinesia.

• 대한한방내과학회지
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• 제38권5호
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• pp.853-861
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• 2017

Objectives: The objective of this study was to report a clinical case that suggests potential beneficial effects of Korean medicine therapy for the treatment of levosulpiride-induced acute dyskinesia. Methods: A patient having drug-induced acute dyskinesia was given a series of Korean medicine therapy treatments, including administration of the herbal medicine Chengsimyeonja-tang-gamibang, acupuncture, electroacupuncture, pharmacopuncture, and moxibustion over the 17 days of the hospitalization period. During the therapy, the progression of the disease was measured by the Abnormal Involuntary Movement Scale (AIMS). Results: During the therapy, the remission of orofacial dyskinesia and improvement of AIMS scores were observed. Conclusion: Korean medicine therapy has potential benefits for the treatment of drug-induced acute dyskinesia.

• 생물정신의학
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• 제10권2호
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• pp.133-140
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• 2003

Objective:Some candidate gene polymorphisms were reported to be associated with tardive dyskinesia (TD). The aim of this study was to investigate the association of the 5-$HT_{2A}$ receptor gene polymorphisms with TD in Korean schizophrenic subjects. Method:Subjects were of 59 schizophrenic patients with TD and 60 schizophrenic patients without TD for studying of 5-$HT_{2A}$ receptor gene polymorphisms. TD was evaluated using the Abnormal Involuntary Movement Scale(AIMS). Genomic DNA was amplified by PCR and digestion with MspI and BsmI. Result:There were no statistically significant differences in the demographic variables, such as age, male to female percentage, duration of illnesses and duration of antipsychotic drug exposure between the TD group and control group. 1) T102C polymorphisms and TD Comparing the TD group and control group, the 102T/C allele was associated with a significantly increased risk for TD (${\chi}^2$=5.560, df=1, p=0.018). 2) Three AIMS categories of TD and T102C genotype. There were statistically significant differences in the three AIMS categories(${\chi}^2$=6.835, df=2, p=0.033). Conclusion:These result suggest 102T/C genotypes of the 5-$HT_{2A}$ receptor gene are related to the development of TD. The 102T/C genotypes were associated with significantly higher AIMS orofacial dyskinesia scores. These findings suggest that the 5-$HT_{2A}$ receptor gene is significantly associated with susceptibility to TD in patients with chronic schizophrenia.

• Journal of Oral Medicine and Pain
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• 제23권4호
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• pp.447-455
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• 1998

A 42-year old male patient was referred to the Department of Oral Medicine, Kyungpook National University Hospital due to the chief complaint of limite mouth opening. Three years ago, the patient was diagnosed as an infarction of both cerefellar hemispheres, acute obstructive hydrocephalus and acute epidural hematoma of frontal lobe at the department of neurosurgery.Both of the infarcted cerevellar hemispheres and the epidural hematoma of frontal lobe were removed with suboccipital and frontal craniectomu. After the brain surgery jaw opening range was decreased progressively and ultimately mouth opening became almost impossible. Spasmodic and rhythmic contractions of the masseter muscles occurred intermittently during daytime as well as sleeping. Food intake was available only through Levin -tube. Actibe jaw opening exercise was prescribed with the aids of tongue blades. A moist hot pack and indomethacin phonophesis were also applied 20 minutes three times a day to decrease discomfort muscle activities. After a month of treatments, the opening range was increased to 5mm at the premolar area and oral food intake was possibel. The L-tube was removed and the patient was discharged.

• 동의신경정신과학회지
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• 제26권3호
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• pp.267-282
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• 2015

Objectives: Tremor is a common disorder causing abnormal movements, it is defined as, "rhythmic, involuntary movements of a part of the body against ones own volition.". The purpose of this study is to report the effects of Korean Medicine (Acupuncture and herbal-medication) for oromandibular tremor resulting from Deficiency Syndrome. Methods: We treated 6 patients suffering from oromandibular tremor who received hospital treatment in DongEui Medical Center from March to June in 2015. Results: After the treatments, oromandibular tremor decreased or disappeared. And some other accompanying symptoms were improved. Conclusions: These results suggests that Korean medical treatments (Acupuncture and herb-medication) might be effective for treating oromandibular tremor resulting from Deficiency Syndrome.

• Journal of Oral Medicine and Pain
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• 제34권4호
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• pp.421-427
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• 2009

구강하악 근긴장이상증(oromandibular dystonia)은 국소적인 근긴장이상증의 한 형태로, 저작근, 안면근 또는 혀 근육의 지속적이고 반복적인 근경련이 발생하여 불수의적인 개구 및 폐구, 악골의 측방 및 후퇴운동이 나타나는 것으로 정의내릴 수 있다. 구강하악 근긴장이상증에 이환된 환자의 경우, 저작, 연하 및 발음을 하는데 불편감을 가지게 되고, 그 결과 하악 운동에 지장을 초래하게 된다. 현재까지는 근긴장이상증에 대한 병태생리가 뚜렷히 입증된 바가 없어, 원인에 관련한 치료는 이루어지지 않고 있는 상태이다. 약물요법, 행동요법, 외과적 처치 등 다양한 방법이 구강하악 근긴장이상증의 치료법으로 제시되고 있으나, 성공률이 그리 높은 편은 아니며, 많은 부작용을 초래할 수 있다. 최근 들어 근긴장이상증에 이환된 근육에 보툴리눔 톡신을 이용한 치료법이 주목을 받고 있는 추세이다. 본 증례를 통해 구강하악 근긴장이상증을 중심으로 한 구강안면 운동장애에 대하여 전반적으로 고찰을 시행하고 해당 질환에서의 보툴리눔 톡신 치료법에 대하여 알아보고자 한다.