• 약학회지
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• 제37권1호
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• pp.84-88
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• 1993

Brovincamine is a selective cerebral vasodilator that was apparently produced via a slow calcium blockade. Brovincamine has been shown to increase ATP production and glucose and oxygen consumption in brain, improving energy metabolism. Also brovincamine inhibited platelet aggregation induced by ADP and collagen in vivo and in vitro via an increase of cAMP concentration, promoting therapeutic effects on cerebral circulatory disorders. So we investigated and represented the clinical effects and safety of brovincamine in patients with cerebral stroke. Thirty patients of cerebral stroke that was older than 2 months, who were 22 cases of cerebral infarction, 6 of cerebral embolism that originated from carebral infarction, 6 of cerebral embolism that originated from cardiac diseases, and 2 of cerebral embolism that originated from cardiac diseases, and 2 of cerebral hemorrhage, were administered of 20 mg of oral brovincamine three times daily for 8 weeks. Improvement rates of each symptom after 8 week administration were 30.8% for subjective symptoms, 76% for psychiatric symptoms and 65.6% for neurologic symptoms. In final global improvement rates, much improvement was 10%, improvement was 23.3% slight improvement is 36.7%, and no change was 30%. So global improvement rate including slight improvement was 70%. As for side effects, there were 3 cases of mild gastrointestinal symptoms, but there were no other subjective side effects and significant fluctuation in laboratory examination. Conclusively throughout the present study, brovincamine is judged to be well tolerated and effective in patients with cerebral stroke.

• Anatomy and Cell Biology
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• 제57권2호
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• pp.316-319
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• 2024

Comprehensive understanding of the variations in the branching of the external carotid artery (ECA) is essential to minimizing vascular complications during cranio-facial and neck surgical procedures. We demonstrate a rare case of unusual branching of ECAs in both carotid triangles and anomalous origin of the left ascending pharyngeal artery (APA) during dissection of embalmed cadaver. The right and left common carotid arteries (CCA) bifurcated at the level of the upper border of the thyroid cartilage. The right superior thyroid artery (STA) originated anterior to the carotid bifurcation (CB), while the left STA originated from the anterior aspect of the left CCA. The right ECA trifurcated into linguofacial trunk, APA, and distal ECA, 15.7 mm from CB. On the left side, lingual artery and APA arose as a short common linguopharyngeal trunk, 1.9 mm from CB. The left facial and occipital arteries originated anteromedially and posteriorly at the same level.

• 한국토양비료학회지
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• 제40권5호
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• pp.383-391
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• 2007

수계 내 농경지로부터의 비점오염은 토양유실과 밀접한 관련이 있어 토양침식 정도를 산정하는 것은 비점오염 관리의 기초가 될 수 있으며 환경오염 예측모델의 정도 향상에도 도움이 될 것이다. 본 연구는 표준유역단위인 소유역에서 토양연접군에 따라 소유역을 분류하고 소유역별로 토양침식 위험성을 산정해 통합적 수계관리의 방향을 제시하고자 수행하였다. 건설교통부 소유역 분류에서 토양조사가 되어 있는 10개의 소유역을 선정해 토양연접군에 따른 분류를 통해 금강본류 21, 남강 03, 동진천, 가평천 01, 경안천 02 소유역은 편마암 유래토양이 50% 이상을 차지하는 편마암 유래토양 소유역 그룹으로 분류되었고, 금강본류 16, 병성천 01, 대신천, 북천 02, 영상강 본류 08 소유역은 화강암 유래토양 면적이 60% 이상인 화강암 유래토양 소유역 그룹으로 분류되었다. 대상유역의 경지이용 형태는 편마암 유래토양이 주로 분포하고 있는 소유역 그룹에서 화강암 유래토양이 주로 분포하는 소유역보다 산림의 면적비율이 높게 나타났고 밭의 분포면적 비율이 그다지 높지 않은 것을 보여주었다. 또한 토양도 상의 경사도 분포는 편마암 유래토양이 주로 있는 소유역에서는 산림면적이 많은 관계로 경사 60% 이상인 E와 F slope이 많았고 화강암 유래토양이 주로 분포하는 소유역에서는 대부분의 유역이 경사도에 따라 고르게 분포하는 경향이었다. 각각의 소유역별 토양유실량 산정에 따른 면적별 분포는 산림이 포함된 관계로 편마암이나 화강암 유래토양 대부분에서 A나 B 등급이 많았으나 전체적으로는 편마암 유래토양이 주가 되는 소유역은 B와 C 등급이 많이 분포하고 있었으며, 화강암 유래토양이 주가 되는 소유역에서는 영산강 08을 제외하면 A와 B 등급에 많이 분포하고 있었다. 산림을 제외하는 경우에는 전체적으로 토양유실 등급의 면적분포가 A 등급이 많아졌고 편마암 유래토양 소유역에서 상대적으로 G 등급의 면적분포가 상승하고 등급별 분포가 고르게 되었다. 소유역에서 경지이용형태별 토양유실량은 논이 가장 작은 값을 보였고, 다음이 산림이었으며 제일 큰 토양유실량을 보인 것은 밭이었다. 토양유실량 산정에 따른 토양연접군별 소유역단위 특성을 살펴보면 송산지곡 연접군으로 분류할 수 있는 편마암 유래토양이 주로 분포하고 있는 소유역들의 연간 평균 토양유실량은 $7.66ton\;ha^{-1}\;yr^{-1}$이었고, 삼각상주 연접군으로 분류되는 금강본류 16, 병성천 01, 대신천, 북천 02 소유역의 평균 토양유실량은 $5.55ton\;ha^{-1}\;yr^{-1}$이었다. 송정백산 연접군으로 분류할 수 있는 영산강 08 소유역의 토양유실량은 $9.6ton\;ha^{-1}\;yr^{-1}$ 이었으나 이 연접 소유역군은 다른 소유역군들처럼 더 많은 분류가 있어야 평균 토양유실량을 산정할 수 있을 것으로 여겨진다. 이런 결과로 보아 토양연접군에 따른 소유역의 분류와 유역그룹별 토양유실량을 산정하면 토양연접군별 소유역그룹의 비점오염 기여도를 파악할 수 있을 것으로 보이며, 이에 따라 다양한 수문 환경 모형들의 적용성을 확대시켜 수계 내 수질 관리의 효율성을 향상시킬 수 있을 것이다.

• 축산식품과학과 산업
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• 제6권1호
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• pp.24-33
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• 2017

• 보존과학연구
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• 통권8호
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• pp.1-12
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• 1987

Fifty ancient Korean coins originated in Choson dynasty have been determined for 9 elements such as Sn, Fe, As, Ag, Co, Sb, Ir, Ru and Ni by instrumental neutron activation analysis and for 3 elements such as Cu, Pb, and Zn by atomicalsorption spectrometry. Bronze coins originated in early days of the dynasty contain as major constituents Cu, Pb and Sn approximately in the ratio 90 : 4 : 3, where as, those in latter days contain in the ratio 7 : 2 : 0. Brass coins which had begun in 17century contain as major constituents Cu, Zn and Pb approximately in the ratio 7 : 1: 1. The multivariate date have been analyzed for the relation among elemental contents through the variance-covariance matrix. The data have been fur theranalyzed by a principal component mapping method. As the results training set of 8class have been chosen, based on the spread of sample points in an eigenvector plotand archaeolgical data such as age and the office of minting.

• Journal of Microbiology and Biotechnology
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• 제30권3호
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• pp.341-351
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• 2020

To shed light on the genetic differences among food-originated coagulase-negative Staphylococcus (CNS), we performed pan-genome analysis of five species: Staphylococcus carnosus (two strains), Staphylococcus equorum (two strains), Staphylococcus succinus (three strains), Staphylococcus xylosus (two strains), and Staphylococcus saprophyticus (one strain). The pan-genome size increases with each new strain and currently holds about 4,500 genes from 10 genomes. Specific genes were shown to be strain dependent but not species dependent. Most specific genes were of unknown function or encoded restriction-modification enzymes, transposases, or prophages. Our results indicate that unique genes have been acquired or lost by convergent evolution within individual strains.

• 한국환경과학회지
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• 제15권12호
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• pp.1185-1191
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• 2006

The high surface area polymer, AquaMats$^{circledR}$ was used for the leachate purification process originated from the Samsan Dong Landfill in Ulsan Metropolitan City. And then, three species of dominant microbes were isolated and identified from AquaMats$^{circledR}$. Gram staining revealed these microbes to be Gram-negative rod strains: They were identified as Agrobacterium radiobacter, Pseudomonas cepacia, Flavobacterium indologenes. All they showed no growth on media in which the leachate was added alone, but a rapid proliferation rate on media with yeast extract as nutrient requirements.

• 한국생물공학회:학술대회논문집
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• 한국생물공학회 2001년도 추계학술발표대회
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• pp.225-228
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• 2001

RhRnBp and Peysn5 are the proteins related to carbohydrate synthesis. RhRnBp originated form human was expressed as inclusion body in E. coli. Peysn5 originated form actinomadura was expressed as low level and inclusion body in E. coli. Ub, Trx, MalE and NusA is used as fusion partner to RhRnBp and Peysn5. The solubility of all fusion protein is NusA > MalE> Trx > Ub. Expression level of RhRnBp fusions in $37^{\circ}C$ is higher than that in $25^{\circ}C$. However in the case of Peysn5. Expression levels in $25^{\circ}C$ were higher. MalE fusion had highest activity in RhRnBp fusions. There were no activity in Peysn5.

• Journal of Chest Surgery
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• 제21권5호
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• pp.911-917
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• 1988

Pulmonary thromboembolism originated most commonly from the venous thrombus, especially deep vein thrombus in the leg, which migrated to and occluded the pulmonary vasculatures. The failure of clot lysis and repeated embolic episodes resulted in the hemodynamic compromise -that is- in the increasing in the pulmonary vascular resistance, which would cause the right ventricle failure[Car Pulmonale]. Under the cardiopulmonary bypass, 20 year old male patient was treated successfully by thromboembolectomy of pulmonary thromboembolism with pulmonary hypertension, which originated from the deep vein thrombus in the leg. The results of radiologic studies and clinical evaluations were excellent in that the postoperative lung perfusion scan showed the newly increased perfusion of post-embolectomy territories and in the arterial blood gas finding of 76 from 66[mmHg] in PaO2. The patient was uneventful and discharged on postop. $ 14 days with anticoagulant continued.

• 대한기계학회논문집
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• 제18권12호
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• pp.3246-3252
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• 1994

The vibration of meshing gear system is originated form teeth deformation, teeth contact ratio, profile error, etc. The gear vibration is classified as whine vibration during meshing and as rattle vibration during idling. In this study, the whine vibration is investigated under the assumption of piecewise linearity of elastic stiffness due to the variation of meshing. Numerical, theoretical and experimental investigations show the existence of the superharmonic components of the second and the third order. consistently It can be concluded that the superharmonic components in whine vibration of meshing gear is originated from the stiffness variation. It also shows that the higher order harmonics are reduced on the increase of motor speed.