• 대한한방내과학회지
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• 제33권1호
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• pp.102-110
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• 2012

Multiple system atrophy (MSA) is a sporadic progressive neurodegenerative disorder characterized clinically by various combinations of parkinsonian, autonomic, cerebellar, or pyramidal signs and pathologically by cell loss, gliosis, and ${\alpha}$-synuclein-positive glial cytoplasmic inclusions in several brain and spinal cord structures. This is a clinical report about a 69-year-old female who had MSA treated by oriental medical treatment and evaluated by Unified Multiple System Atrophy Rating Scale (UMSARS). The patient was treated with herb medicine Chungsimyeonj-aeumgami(淸心蓮子飮加味), acupuncture, moxibustion and cupping. After treatment, the patient's symptoms improved meaningfully and the score decreased in UMSARS Part I, II. This suggests that oriental medical treatment could be effective to improve MSA patients' symptoms. It is necessary to have more observations and many cases of patients with MSA.

• 대한중풍순환신경학회지
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• 제11권1호
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• pp.1-8
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• 2010

Objectives : We designed this study to investigate difference of heart rate variability(HRV) according to sex, age, acute or chronic phase, category of stroke, national institute of health stroke scale(NIHSS), lesion of stroke. Methods : 64 subjects were recruited from the patients admitted to the department of oriental medicine at East-West Neo Medical Center, Kyung Hee University from 1 September 2009 to 31 August 2010. We compared heart rate(HR), standard deviation of all normal P-P intervals(SDNN), low frequency(LF), high frequency(HF), LF/HF ratio. Results and Conclusions : 1. LF/HF ratio is significantly different between over-70 and below-70 of age. 2. SDNN is significantly different between acute and chronic stroke patients. 3. In sex, category of stroke, national institute of health stroke scale(NIHSS), lesion of stroke, there are no significantly different among the any values of heart rate variability(HRV).

• 대한중풍순환신경학회지
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• 제11권1호
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• pp.26-35
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• 2010

Objective : The aim of this study was to examine the characteristics of the acute stroke patient who take Gwakhyangjeonggisan, and provide the basis of Gwakhyangjeonggisan prescription Method : We studied hospitalized patients within 4 weeks after their ictus who were admitted at Kyunghee University Oriental Medical Center, Kyunghee University East-West Neo Medical Center, Kyungwon University Oriental Medical Center, Semyung University Oriental Medical Center from February 2010 to July 2010 We compared the general characteristics of acute stroke patient according to herb medicine Result : The patient who take Gwakhyangjeonggisan show significant difference for sex, family history of Stroke, Face color, Tongue color, Pulse condition, HDL Cholesterol, Fastfood eating, Waist circumference. Conclusion : The above result show that Gwakhyangjeonggisan can be prescribed to stroke patient whose complaining gastrointestinal symptoms, & Oriental Medical Diagnosis is Cold & Deficiency type. Further studies will be needed to better understand the difference between Gwakhyangjeonggisan group and Other herb medicine among acute stroke patients.

• 동의신경정신과학회지
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• 제20권2호
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• pp.177-186
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• 2009

Objectives : We investigated if korean traditional treatment and psychotherapy is effective in patients with depression and menopausal symptoms. Methods : We treated two patients with typical korean traditional medical treatment( Acupuncture, Giungoroen therapy(至言高論療法), Moxibustion ) and progressive muscle relaxation. Results : After treatment, the chief complaint and accompanying symptoms were subsided and improved. BDI score and Kupperman's index were decreased. Conclusions : We may conclude that korean traditional treatment and psychotherapy is effective in patients with depression and menopausal symptoms.

• 혜화의학회지
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• 제14권2호
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• pp.93-105
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• 2005

Objective : We investigated the actual condition of oriental medical office in a public health center. Methods : We classified patients who visited an oriental medical office iin a public pealth center of Dalseong-gun, Daegu Metropolitan City during recent 3 years by KCPJMAIN(data processing system), according to location, age, time(month, year), sex, disease, insurance, etc. Results : As a local category, the residents in Hyeunpung-Myeon higher than 80% of the patients who visited the public health center. The patients aged over 60 occupied 80% of the patients. The frequency of the treatment was more than 10 in those patients aged over 60. The number of the patients was the highest in May when there was a change for the past 36months, whereafter the number has sustained decline for 3-5 months and repeated decreasing. As a gender category, the female inpatients were 10732(82%). This statistics shows that these musculoskeletal system disease occupied large part in them. As a heath insurance category, the patients who were insured by health care were 12454(96.30%). Conclusion : It should need to enable the rural residents who have difficulty benefitting from medical service to reach the service by making their access to the oriental medical office in public health center easier. Most of all, the support from both government and municipality should be urged to accomplish it. plus, it should be included not only boosting doctors' reliance but also improving the capability and services of doctors in public heath center. In conclusion, the treatment service in public health center should be diversified beyond musculoskeletal system disease and the identity transform of public health center should be needed to appeal to young generation.

• Journal of Acupuncture Research
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• 제18권6호
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• pp.135-140
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• 2001

Objective : To investigate the effects of Acupuncture therapy on the migraineur by way of the change of the Cerebral blood flow. Methods : 6 migraineurs were inserted in acupoints on GV16, G20, S8 during 2 weeks. and, Mean Velocity (MV) and Pulsatility Index (PI) of MCA, PCA, ACA, BA were measured before and after treatments of 2 weeks, respectively. Results : MV of MCA of the migraineurs was decreased very much by 13.3%, and PI was decreased much by 10.4%. However, MV and PI of BA changed little. Conclusion : It is observed that Acupuncture therapy reduces pains of migraineur through decreasing Cerebral blood flow like MCA.

• 동의생리병리학회지
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• 제20권1호
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• pp.10-14
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• 2006

A survey was practiced to the medical doctors of Je-Han Medical Center and Taegu Catholic Medical Center from November to December 2004. The collected data was analysed by the SPSS10+. The analysis of frequency, cross table, the difference of mean was practiced. The focus of the analysis was to find the difference of attitudes between Korean Oriental medical doctors and Western medical doctors. The results of the analysis showed that Korean Oriental medical doctors are more active to the cooperated medical treatments than Western medical doctors. They also have more experience. And both of Korean Oriental medical doctors and Western medical doctors agree to the necessity of the cooperated medical treatments. But the preferred combination pattern of Korean Oriental medicine and Western medicine was different between two medical groups. Korean Oriental medical doctors prefer the one to one combination pattern. But Western medical doctors prefer to Western medicine centered combination pattern. This study has limitations in sampling prcesss and sample size. But considering that the study of the cooperated medical treatments is few, this study has considerable medical sociological meaning.

• 대한한의학회지
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• 제33권2호
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• pp.47-55
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• 2012

Objectives: This study aimed to investigate the preventive effect of red ginseng (RG) on 5-fluorouracil (5-FU)-induced side effects focusing on myelosuppression. Methods: Rats (n = 50) were divided into five groups, nave, control (ip, 5-FU injection of 150 mg/kg), and RG pre-treatment (po, 25, 50 and 100 mg/kg for 5 days before 5-FU injection). On the $7^{th}$ day after 5-FU injection, we evaluated the effects using peripheral hematological parameters, colony-forming assay, cytokine levels and histopathological finding. Results: The peripheral white blood cell and the differential count were dramatically suppressed by 5-FU, while RG (50 and 100 mg/kg) treatment significantly improved total white blood cell, neutrophil, lymphocyte and platelet counts. Also, RG (100 mg/kg) pre-treatment significantly increased the number of CFU-GM colony compared with the control group. RG pre-treatment also ameliorated the histopathological damage in bone marrow, spleen, stomach and small intestine tissue. Conclusions: These results demonstrate that Korean RG has preventive effects against 5-FU-induced myelotoxicity and gastrointestinal damage.

• 대한한방소아과학회지
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• 제16권1호
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• pp.1-8
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• 2002

Back ground: The purpose of this study was to examine the patient's satisfaction of Sympathicotomy and clinical observation by Oriental medicine. Methods: We studied 93 hyperhidrosis patients after Sympathicotomy. They were treated on East-West Hyperhidrosis Clinic, Kyung Hee University Medical Center, from October 1999 to February 2002. Resurt and Conclusion: The most patients were satisfied with treatment effects of Sympathicotomy and there were few side effects. The only complain was compensatory sweating. Sympathicotomy can be recommended as a useful treatment for hyperhidrosis. Clinical study by Oriental medicine on hyperhidrosis patients was showed that hyperhidrosis could be observed at Taeeumin, Soyangin and Soeumin. We can find the new treatment of compensatory sweating, by Sasang Constitutional Medicine and Oriental diagnosis.

• Molecular & Cellular Toxicology
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• 제4권4호
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• pp.331-337
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• 2008

This study was conducted to quantitatively evaluate the recovery effects of herbal medicines on acetaminophen-induced hepatotoxicity. In the present study, the recovery effects of 251 herbal medicines on THLE-2 cells that had been damaged by acetaminophen were evaluated using an MTS assay. THLE-2 cells were cultured in 96-well plates and then pretreated with or without 60 ${\mu}M$ acetaminophen (${IC}_{50}$ value: 35.84) for 1 hr. Next, different herbal medicines were added to the wells, after which the cells were reincubated at $37^{\circ}C$ for 24 hr. After first round of screening, the candidate herbal medicines were selected based on a recovery rate of greater than 40% and their efficacy were then determined by dose response kinetic analysis. Among these extracts, 8 herbal medicines (Terminalia chebula, Pueraria lobata, Acronychia laurifolia, Lopatherum gracile, Oroxylum indicum, Cynanchum atratum, Senecio scandens, and Sophora flavescens) had a strong recovery effect on acetaminophen-induced damage in THLE-2 cells. Dose response non-linear regression analysis demonstrated that Senecio scandens showed the best recovery rate (98%), and that its ${EC}_{50}$ was 19.54 ng/mL. Additional studies of these herbal medicines should be conducted to determine if they possess novel therapeutic agents for the prevention or treatment of liver disorders.