• Title/Summary/Keyword: oriental herb medicine

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A Clinical report on psychogenic torticollis (심인성 사경증 환자 치험 1례)

  • Ahn, Hyo-Jin;Seo, Deok-Won;Ryu, Ho-Sun;Ko, In-Sung;Lee, Su-Bin;Park, Se-Jin
    • Journal of Oriental Neuropsychiatry
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    • v.22 no.2
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    • pp.61-69
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    • 2011
  • Objectives : The purpose of this study was to investigate the clinical application of Korean Traditional treatment to psychogenic torticollis patient who has panic disorder as underlying disease. Methods : Herb medicine used in this study are Heosu-san(Huishou-san) which is previously used for torticollis in several studies, Guibi-tang(Guipi-tang) and Gamiondam-tang(Jiaweiwendan-tang) which are frequently used for phychological disease. Also, physical therapy and aroma therapy were practiced which basically stretches and relaxes muscles around cervical muscles. Self exercise of cervical muscles was carried out during acupuncture. Results : After the comprehensive treatment, the clinical symptoms of the patient were improved. Conclusions : It is suggested that oriental medical treatment are effective in psychogenic torticollis.

Quantitative Analysis of the Three Marker Compounds in Sanguisorbae Radix by Processing Method (포제에 따른 지유의 지표성분 함량분석)

  • Seo, Chang-Seob;Kim, Jung-Hoon;Shin, Hyeun-Kyoo;Kim, Byoung-Soo
    • Korean Journal of Pharmacognosy
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    • v.46 no.4
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    • pp.342-351
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    • 2015
  • In this study, we performed quantitative determination of the three marker compounds such as gallic acid, ellagic acid, and quercetin in the 70% ethanol extracts of non-processed Sanguisorbae Radix and processed Sanguisorbae Radix using a high-performance liquid chromatography coupled with photodiode array detector. The analytical column for separation of the three compounds was used a Gemini $C_{18}$ column ($5{\mu}m$, $4.6{\times}250mm$) by the gradient elution with distilled water and acetonitrile containing 1.0% (v/v) acetic acid as mobile phase. The flow rate and injection volume were $1.0{\mu}L/min$ and $10{\mu}L$. The concentrations of gallic acid, ellagic acid, and quercetin in non-processed Sanguisorbae Radix were 0.25, 0.26, and 0.007%, respectively, while the concentrations of gallic acid, ellagic acid, and quercetin in non-processed Sanguisorbae Radix 0.14-0.55, 0.27-2.03, and 0.001-0.007%, respectively. Among the three components, the amount of the ellagic acid was increased after processing in Sanguisorbae Radix.

Quantitative Determination of the Six Marker Compounds in Eucommiae Cortex by Processing Method (포제에 따른 두충의 지표성분 함량분석)

  • Seo, Chang-Seob;Kim, Jung-Hoon;Shin, Hyeun-Kyoo;Kim, Byoung-Soo
    • Korean Journal of Pharmacognosy
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    • v.46 no.2
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    • pp.123-132
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    • 2015
  • In this study, we carried out quantification analysis of the six marker components, geniposidic acid, chlorogenic acid, geniposide, pinoresinol diglucoside, liriodendrin, and genipin in the 70% ethanol extracts of non-processed Eucommiae Cortex and processed Eucommiae Cortex using a high-performance liquid chromatography coupled with photodiode array detector. The six components were separated on Gemini C18 column (5 μm, 4.6×250 mm) by the gradient elution with 1.0% (v/v) acetic acid in water and 1.0% (v/v) acetic acid in acetonitrile as mobile phase. The flow rate was 1.0 mL/min and the injection volume was 10 mL. The amount of geniposidic acid, chlorogenic acid, geniposide, pinoresinol diglucoside, liriodendrin, and genipin in non-processed Eucommiae Cortex were 1.31, 0.31, 0.66, 0.46, 0.46, and 0.03%, respectively, while the amount of the six compounds in non-processed Eucommiae Cortex were 0.04-0.78, 0.01-0.14%, 0.05-0.63%, 0.01-0.37%, 0.15-0.42%, and not detected, respectively. After processing treatment, the contents of three iridoids, two lingnan, and one phenylpropanoid decreased in Eucommiae Cortex.

Compilation of 104 Experimental Theses on the Antitumor and Immuno-activating therapies of Oriental Medicine (한의학의 항종양 면역치료에 관한 연구 -1990년 이후 발표된 실험논문을 중심으로-)

  • Kang Yeon Yee;Kim Tai Im;Park Jong Ho;Kim Sung Hoon;Park Jong Dai;Kim Dong Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.1
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    • pp.1-24
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    • 2003
  • This study was done to compile 104 experimental theses which are related to the antitumor and immuno-activating therapies between February 1990 through February 2002. Master's and doctoral theses were dassified by schools, degrees, materials, effects, experimental methods of antitumor and immunoactivity, and results. The following results were obtained from this study : 1. Classifying the theses by the school, 34.6% were presented by Daejeon University, 29.8% by Kyung-hee University and 11.5% by Won-kwang University. Of all theses, 51.0% were aimed for the doctoral degree and 43.3% were for the master's degree. All of three universities have their own cancer centers. 2. Classifying the theses by herb materials, complex prescription accounted for 60.3%, single herb accounted for 24.8% and herbal acupuncture accounted for 14.2%. Considering the key principles of the traditional medicine, complex prescription was much more thoroughly studied than single herb prescription. The results showed that the complex prescription had both antitumor activity and immuno-activating activity, which might reflects on multi-activation mechanisms by complex components. 3. Classifying the theses by the efficacy of herbs examined, in single herb, invigorating spleen and supplementing was 35.5%, expelling toxin and cooling was 29.0%, activating blood flow and removing blood stasis was 12.9%. In herbal acupuncture, invigorating spleen and supplementing was 52.9%, expelling toxin and cooling was 29.4%. In complex prescription, pathogen-free status was 41.9%, strengthening healthy qi to eliminate pathogen was 35.5%, strengthening healthy qi was 22.6%. It is presumed that the antitumor and immunoactivating therapy based on syndrome differentiation is the best way to develop oriental oncology. 4. Classifying the theses by antitumor experiments, cytotoxic effect was 48.1 %, survival time was 48.1 % and change of tumor size was 42.3%. Survival rate was not necessarily correlated with cytotoxicity. These data reflect the characteristic, wholistic nature of the oriental medicine which is based on BRM (biological response modifier). 5. Classifying the theses by immunoactivating experiments, hemolysin titer was 51.0%, hemagglutinin titer was 46.2% and NK cell's activity was 44.2%. In the future studies, an effort to elucidate specific molecular and cellular mechanisms of cytokine production in the body would be crucial. 6. Classifying the theses according to the data in terms of antitumor activity, 50% was evaluated good, 24.0% was excellent, and 15.5% have no effect. In an evaluation of immuno-activating activity, 35.9% was excellent and 18.0% showed a little effect. The index point, as described here, may helps to use experimental data for clinical trials. Changes in index points by varying dosage implicate the importance of oriental medical theory for prescription. 7. In 167 materials, IIP (immunoactivating index point, mean : 3.12±0.07) was significantly higher than AIP(antitumor index point, mean : 2.83±0.07). These data demonstrate that the effect of herb medicine on tumor activity depends more on immunoactivating activity than antitumor activity. This further implies that the development of herbal antitumor drugs must be preceded by the mechanistic understanding of immunoactivating effect. 8. After medline-searching tumor and herb-related articles from NCBI web site, we conclude that most of the studies are primarily focused on biomolecular mechanisms and/or pathways. Henceforth, we need to define the biomolecular mechanisms and/or pathways affected by herbs or complicated prescriptions. 9. Therefore, the most important point of oriental medical oncology is to conned between experimental results and clinical trials. For the public application of herbal therapy to cancer, it is critical to present the data to mass media. 10. To develop the relationship of experimental results and clinical trials, university's cancer clinic must have a long-range plan related to the university laboratories and, at the same time, a regular consortium for this relationship is imperative. 11. After all these efforts, a new type herbal medicine for cancer therapy which is to take care of the long-term administering and safety problem must be developed. Then, it would be expected that anti-tumor herbal acupuncture can improve clinical symptoms and quality of life (QOL) for cancer patients. 12. Finally, oriental medical cancer center must be constructed in NCC (National Cancer Center) or government agency for the development of oriental medical oncology which has international competitive power.

Clinical Study of twenty four patients complained of the tremor (진전환자 24례에 대한 증례 보고)

  • Park, Hye-Sun;Bae, Young-Chun;Joo, Jong-Cheon
    • Journal of Sasang Constitutional Medicine
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    • v.14 no.2
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    • pp.153-159
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    • 2002
  • To study clinical characteristics of patients complained of the tremor, I analyzed a database of twenty four patients managed at the Sasang Constitutional Department in Wonkwang University Oriental Medical Hospiyal from June 1999 to October 2000. 54% of patients who had adequate follow-up were improved with herb medication, electric acupuncture, physical therapy, aromatherapy. 46% of them were not improved in spite of above mentioned treatment. None of patients was aggravated. 71 % of them have male sex and 42% in 7th decade. The distribution ratio was 46% Soyang Constitution, 42% Taeumin Constitution, 13% Soum Constitution. I diagnosed 75% of them as essential tremor or physiological tremor or neurosis. Most of them had the tremor in upper extremities. The period of history were various distribution. Herb medicines were used in the Sasang Constitutional Theory. The Sasang Constitutional Medicine has the significant effects of treating patients complained of the tremor..

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A Clinical Case Study on Postural Brachial Plexus Injury with Whole Body Articulation-Mechanics Technique (추나요법을 적용한 체위성 상완신경총 손상 치험 1례)

  • Chang, Dong-Ho;Kang, Yeon-Kyeong;Cho, Sung-Woo;Lee, Young-Seok
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.5 no.2
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    • pp.49-55
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    • 2010
  • This study was performed to report the effect of oriental medical treatment and general biomechanic manipulation on a patient with upper limb palsy caused by postural brachial plexus injury. The patient was treated with acupuncture, herb medicine and general biomechanic manipulation. The effectiveness of treatment was evaluated with range of motion, visual analogue scale and manual muscle test. After 11 times treatment, motion and muscular force were progressed, pain was decreased. This result suggests that oriental medical treatment and general coordinative manipulation are effective to care the postural brachial plexus injury.

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A Study on Antimicrobial Activity of Veratri Herba (여로의 항균작용에 관한 연구)

  • Chi Gyoo Yong
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.16 no.1
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    • pp.95-98
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    • 2002
  • This study was carried out to investigate the efficacy of antifungal and antibacterial activity of Veratri Herba, which was used as insecticide in the clinical part of oriental dermatology for a long time. Sample herb was selected with Veratrum maackii in the middle of 5 veratrum species. The experimental results of this herb were as follows. Crude extract showed various relative inhibitory rates from 68.9% to 95.6% in 2mg/disc against Fusarium oxysporum, Botrytis cineria, Saccharomyces cerevisiae, Escherichiae coli, and Bacillus subtilis on the basis of inhibitory range against B. cineria, and the inhibitory effect was decreased depending on density. In the extract of various organic solvent, chloroform and ethyl acetate fraction show the various size of dear zone against all microbes. And in the subfraction assay from ethyl acetate fraction, crude alkaloids show the antibacterial and antifungal effect significantly.

A Comparative Study of BMD between Osteoporosis Patients Taking Fosamax and Taking Fosamax and Samgieumgamibang (골다공증 환자에 대한 Fosamax 단독복용군과 삼기음가미방 병용투여군의 유효성 비교분석)

  • Yu, Sung-Jin;Ahn, Hee-Bin;Kim, Ji-Young;Lee, Dong-Nyung
    • The Journal of Korean Obstetrics and Gynecology
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    • v.25 no.1
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    • pp.11-19
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    • 2012
  • Purpose: The purpose of this study is to evaluate the synergic efficacy of oriental herb medicine for osteoporosis patients by examining whether there is any change in BMD. Osteoporosis patients are classified into a group having taken Fosamax and the other group having taken Fasamax and Samgieumgamibang in this study. Methods: Mean BMD and T-score are measured in all patients before and 3 months after treatment. Results: 1. The group having taken Fosamax showed no statistically significant mean BMD change before and after treatment. 2. The group having taken Fosamax showed no statistically significant T-score change before and after treatment. 3. The group having taken both Fosamax and Samgieumgamibang showed increase in mean BMD, which does not bear statistically significant change. 4. The group having taken both Fosamax and Samgieumgamibang showed statistically significant T-score change before and after treatment(p<0.05). Conclusions: After treatment, BMD in patients having taken Fosamx did not change significantly, but in patients having taken both Fosamax and Samgieumgamibang increased, which proves the efficacy of oriental herb medicine for osteoporosis patients.

A Case Report of Postpartum Disease Induced by Inadequate Postpartum Care (잘못된 산후관리로 인한 산후질환 1례 보고)

  • Lee, Jin-Moo;Lee, Chang-Hoon;Cho, Jung-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub;Kim, Eun-Sook
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.3
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    • pp.238-245
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    • 2007
  • Purpose: In postpartum period, women are very weak and liable to various diseases. So postpartum care is very important. But excessive heating and sweating cause postpartum diseases. Methods: The patient in this case, 37 years-old female was in Kyunghee University East-West neo medical center for 8days(27th/Oct/2006 - 3rd/Nov/2006). Her chief complains when she was admitted in the hospital were sweating, chilling, and mild dizziness. These symptoms were caused by excessive heating and sweating. We thought that her condition was deficiency of Qi. After giving her the therapies with herb medicine, acupuncture and moxibustion, her symptoms got almost disappeared and her condition got better. Results: After the oriental medical treatment, the clinical symptom of postpartum disease was improved. Conclusion: This case study shows that excessive heating and sweating cause postpartum diseases and the oriental medical therapy is effective in treating postpartum disease. And the guideline of postpartum care is needed.

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A Case Report of the Patient with Trigeminal Neuralgia Treated by Bee Venom Pharmacopuncture Therapy (봉약침으로 호전된 삼차신경통 환자 1례에 대한 증례 보고)

  • Jeong, Seon-Mee;Kim, Ja-Young;Park, Chan-Kyu;Min, Eun-Kyeong;Sohn, Sung-Chul
    • Journal of Acupuncture Research
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    • v.25 no.5
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    • pp.197-204
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    • 2008
  • Objectives : This is a clinical report about the 47-year-old female patient with Trigeminal Neuralgia(TN) treated by oriental medicine treatment including Bee Venom Pharmacopuncture therapy(BVP), without any western medical treatment. Methods : The patient was treated by acupuncture, herb medication, and BVP. The improvement of the patient was judged by Visual Analog Scale(VAS). Results : The pain was gradually reduced and VAS became 0 after 8 days of treatment. Since then the pain didn't reappeared for 6 months. Conclusions : Oriental medicine treatment including BVP was very effective to improve the TN patient's symptoms. It is necessary to have more observation and many cases of patients with TN.

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