• 제목/요약/키워드: orient

검색결과 322건 처리시간 0.025초

산초의 약물대사효소 CYP3A4 저해 활성 (Inhibitory Activity of Drug-metabolizing Enzyme CYP3A4 of Zanthoxylum Peel)

  • 차배천
    • 생약학회지
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    • 제50권3호
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    • pp.159-164
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    • 2019
  • Zanthoxylum Peel is widely used as a common spice for a variety of foods. In the orient, it has also been used as traditional agents for treating diseases such as indigestion. Recently, Zanthoxylum Peel has been reported to have anti-cancer activity, anti-microbial activity, and anti-inflammatory activity. Chemical components are known sanshool compounds and xanthoxylin. In this study, we were carried out to investigate the constituents of inhibiting a drug metabolizing enzyme CYP3A4 from Zanthoxylum Peel. CYP3A4 is known as an enzyme involved in drug metabolism as monooxygenase containing the heme. As a result of experiment, we found that bergapten ($IC_{50}=18.21{\mu}M$) and quercetin ($IC_{50}=17.27{\mu}M$) isolated from EtOAc extract of Zanthoxylum Peel showed remarkable CYP3A4-inhibiting activities. Structures of the isolated active compounds were established by chemical and spectroscopic means.

Differentiation and authentication of Panax ginseng (Korea and China), Panax quinquefolius, and development of genetic marker by AFLP analysis.

  • Jeong, Jae-Hun;Jung, Su-Jin;Yun, Doh-Won;Yoon, Eui-Soo;Choi, Yong-Eui
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.157.2-157.2
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    • 2003
  • Panax ginseng is one of the most important medicinal plant in the Orient. The international trade of ginseng is increasing yearly. The disguise of Chinese and American ginseng into Korean ginseng became a problem in recent years in Korea and an abroad. Obviously, an effective method of authentication of Korean ginseng from others at a DNA level, is necessary for the healthy development of the ginseng market. In order to develop convenient and reproducible methods for the identification of Korean ginseng, amplified fragment length polymorphism (AFLP) analysis was applied within Panax species (Korean cultivatied and wild ginseng, Chinese wild ginseng, American cultivatied and wild ginseng). (omitted)

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동·서양 해자(垓字) 문화의 현대적 가치 재조명 (Review of the Modern Values of East and West Moat Culture)

  • 정용조
    • 한국전통조경학회지
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    • 제35권1호
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    • pp.25-35
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    • 2017
  • 본 연구는 성의 외곽에 군사적 방어 역할을 하거나 이를 경계로 공간을 구분하고 기후변화로 인한 온도 상승과 동물들의 서식처 감소 등 악화되어 가고 있는 현대 환경에 미기후를 조절하고, 동물의 서식처를 제공하는 등 다양한 기능을 가진 해자를 현대도시공간에 활용하기 위해 해자의 현대적 가치를 재조명해 본 것으로 연구의 범위는 성의 외곽에 군사적 방어 역할을 위해 파 놓은 못 또는 물길로 적이 성벽에 직접 접근할 수 없도록 하거나 이를 경계로 구분하고자 설치된 해자가 있는 성을 중심으로 동양에서는 한국의 낙안읍성, 해미읍성, 경주월성과 중국의 자금성, 일본의 니조성과 오사카성을 대상으로 하였으며, 서양에서는 영국의 에든버러성과 프랑스의 블루아성, 스위스의 시옹성, 덴마크의 프레데릭스보르성을 대상으로 하였다. 연구의 방법으로는 문헌조사와 현지조사를 통해 연구를 진행하였다. 동양은 문헌조사와 현지조사를 병행하여 실시하였으며, 서양은 문헌조사를 위주로 진행하였다. 문헌조사를 통해서는 해자의 기원과 해자의 개념, 해자의 기능, 서양 해자의 역사와 문화 등에 대하여 관계기관과 선행연구의 자료를 기준으로 하였으며 동양의 현지조사는 한국의 낙안읍성, 해미읍성, 경주월성, 중국의 자금성, 일본의 니조성, 오사카성을 2016년 1월부터 2016년 12월까지 각 대상지별로 총 2~3회에 걸쳐 답사를 실시하였다. 조사내용은 각 대상지의 해자에 대한 기능과 규모, 특징 등에 대하여 관계자 인터뷰, 사진촬영, 실측, 관찰 등의 방법을 통해 조사 분석하였으며, 본 연구의 결과는 다음과 같다. 해자는 성 외곽에 군사적 방어시설과 경계를 구분하고자 설치된 시설물로서 동 서양의 고대로부터 중세에 이르기까지 성과 함께 도시를 구성하는 요소로 중요한 역할을 하였다. 해자가 군사적 방어 목적이 소멸되면서 역할도 점차 사라져 가고 있으나 물이 가득한 해자는 다양한 문화 활동과 동물들의 서식처 제공 등 역사와 문화적 가치가 큰 친수공간임에도 불구하고 현대 조경 계획에 있어 배제되고 있는 실정이다. 다양한 기능을 가진 해자를 현대도시에 반영, 활용함으로써 공기 순환이 막힌 도시에 쾌적한 공기를 유입시키고 수경요소로서 도시에 활력을 불어 넣을 수 있는 해자를 아파트, 공원지역 등에 조경요소로 적극 활용될 수 있기를 기대한다.

우리나라 국민의 비타민과 무기질 급원식품(I) -칼슘과 철분의 급원식품- (Food sources of vitamin and mineral for Korean people(I) -calcium and iron rich foods-)

  • 김영남;나현주;강희자
    • 한국가정과교육학회지
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    • 제12권2호
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    • pp.47-64
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    • 2000
  • The purpose of this study was to search the calcium and iron rich foods in Korean people. The food sources presented in the current home economics textbooks of middle and high school were investigated. And 40 kinds of calcium and iron rich foods were selected by the quantity in 100g edible portion. one serving size and according to 1997 food supply data. Also 3 major food groups of calcium and iron supply in Korean were identified, and 10 rich foods for each food groups were selected. The results were summarized as follows. 1. The food sources of calcium 1) The food sources of calcium presented in the home economics textbooks of middle and high school are milk and dairy products. small fishes such as anchovy icefish and dried strip and green vegetables etc. 2) The calcium rich foods by 100g edible portion were in order of skim milk powder river snail sesame sea mustard. whole milk powder. snapping turtle loach sea tangle(dried) opossum shrimp and sea lettuce(dried). And the calcium rich foods by the calcium content in one serving were in order of river snail snapping turtle opossum shrimp loach spiny lobster skate skim milk powder small alaska pollack freshwater crab condensed milk whole milk powder skate ray and milk. 3) The 3 major calcium supply food groups in Korean were vegetables fish and shellfishes and milk and dairy products. 4) The calcium supply foods according to the quantity of food supply in 1997 was in order of sea mustard, milk anchovy chinese cabbage soybean skin milk powder laver shrimp welsh onion and maize. The vegetables were the important sources of calcium in Korean. 2. The food sources of iron 1) The food sources of iron which are commonly presented in the textbooks of middle and high school were meat liver egg(egg yolk) and green vegetables etc 2) The iron rich foods on the basis of the iron content in 100g edible portion were in order of surf clam marsh clam laver(dried)( sea lettuce(dried), crayfish pelilla seed little neck clam orient hard clam, venus clam, and freshwater carab. And the iron rich foods by the iron content in one serving were in order of surf clam marsh clam crayfish little neck clam orient hard clam freshwater crab venus clam hen cockle green confertii(fresh) pen shell and spiny lobster. 3) The 3 major iron supply food groups in Korean were cereals an cereal products fishes and shellfishes and vegetables. 4) The iron supply food according to the quantity of food supply in 1997 was in order of soybean sea mustard maize rice meat edible viscera laver wheat flour, pook, red pepper, egg and bovine meat.

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수산식품 중 노인성 퇴행성 질환과 관련된 알루미늄 함량 및 그에 따른 수산식품의 이용방안에 관한 연구 (The Study on the Aluminum Content in Fishes Caught from Several Areas of the West Coast in Korea)

  • 김애정
    • 동아시아식생활학회지
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    • 제7권4호
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    • pp.512-518
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    • 1997
  • 알루미늄 등 중금속 오염이 점점 심화되고 있는 서해안 일부지역에서 포획되고 있는 46종의 어패류 중 알루미늄 함량의 평균은 88.38$\pm$189.03ppm으로 그 범위는 0.97-827.70ppm이었는데 24종의 생선 중 알루미늄 함량은 그 범위가 0.97ppm에서 45.12ppm으로 건실치에 가장 많았고 도미에 가장 적게 함유되어 있었다. 15종의 연체류가 함유하고 있는 알루미늄 함량은 3.40ppm에서 827.70ppm으로 그 차이가 매우 컸는데 복족류인 소라에 3.40ppm으로 가장 적게 함유되어 있었고 이매패류인 대합에 826ppm, 해락에 812.55ppm으로 가장 많이 함유되어 있었다. 7종의 젓갈의 알루미늄 함량은 2.50-295.15ppm으로 그 차이가 컸는데 황새기젓과 한치젓에는 그 함유량이 낮았지만 조개젓과 곤쟁이젓에는 많은 양의 알루미늄이 함유되어 있었다 생선과 연체류 및 젓갈중에 함유되어 있는 알루미늄 함량간의 유의차를 검증한 결과 연체류의 알루미늄 함량이 생선과 젓갈에 비해 유의적으로 높았다(p<0.01), 이는 일생동안 주거지를 크게 움직이지 않는 생육조건을 갖는 이매패류의 특성때문으로 사료된다.

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토사자(Cuscuta japonica Choisy, 菟絲子)의 화장품 약리활성에 관한 연구 (Study of the Cosmeceutical Activities of Cuscuta japonica Choisy)

  • 조우아;천순주;장민정;성지연;정수현;강보연;최은영;정연숙;이준숙;최호정;백욱진;안봉전;이창언;이진태
    • 대한본초학회지
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    • 제21권2호
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    • pp.103-108
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    • 2006
  • Objectives : The cosmeceutical activity of Cuacuta japonica Choisy were investigated for cosmetics industrial application. Methods : Cosmeceutical activities include antioxidant, tyrosinase inhibition effects and nitrite-scavenging ability were examined through the Cuacuta japonica Choisy Results : The result were obtained as follows : The electron donating ability of water and ethanol extract was 69.5%, 78.3% at 1,000ppm. In SOD-like activity, water extract showed low effect, but ethanol extract scored 63.4% at 1,000ppm. In inhibition activity of xanthine oxidase, water extract showed low effect, which is 27.2% at 500ppm, in contrast to ethanol extract high effect: 99.5% at 500ppm, in nitrite-scavenging ability test, 500ppm of C. japonica Choisy water extract showed the effect of 51.3%, while 500ppm of C. japonica Choisy ethanol extract showed the effect of 72.7%. From the test of inhibitory effect of tyrosinase, both water and ethanol extract showed insufficient inhibitory rate. Conclusion : According to all the test results that have been given, it is possible that the extract of C. japonica Choisy can be used as a new natural material of the cosmeceutical industry.

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현대(現代)패션에 나타난 동양자수(東洋刺繡)에 관(關)한 연구(硏究) (A Study on Oriental Embroidery through the Modern Fashion)

  • 김소영;심화진
    • 패션비즈니스
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    • 제6권2호
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    • pp.41-52
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    • 2002
  • At the beginning of the modern times, orientalism and ethnic character was the main stream of current fashion. Early in the twentieth century, orientalism had a tremendous affect on various areas of society, culture, and art. Particularly, it inspired and activated the design of costume. A great variety of colors and construction of the Orient and geometrical simplicity were based on the creation of modern costume. Ethnic placed weight on the Orient because Japan strengthened competitiveness and China opened the door to foreign countries. Therefore, a large number of the oriental costume produced by a variety of fashion designers. The oriental handicraft, motif and colors of the traditional costume have been used in modern costume. In addition, they are precious ideas for designers. This thesis is about a Study on costume embroidery close to fashion through the oriental embroidery and the concept of oriental embroidery. It is also a study on patterns, skills and colors of the oriental embroidery shown in modern fashion and practical use through the designers works. First, concept, process of change, patterns, skills and colors of the oriental embroidery are mainly discussed. 1.The oriental embroidery consists of life, Buddhism, appreciation and costume embroidery. Embroidery was widely used for a variety of purposes. First, it is to make a good impression and beauty. Second, to decorate many kinds of patterns and shapes. Last, to indicate social status and stages. 2.The origin of the oriental embroidery started in Persia. was It greatly developed in Iran and was introduced in Korea via China. We are reminded of the oriental embroidery of China. China is the original place of oriental embroidery. Oriental embroidery has developed the peculiar embroidery according to each climate, custom and nationality. On the basis of these, the practical use of the oriental embroidery on modern fashion is presented through patterns, skills and colors which leads Korean designers use. Even though the oriental embroidery is not very popular among people owing to a great deal of cost and a demand for labor, the patterns and colors of the embroidery has been already familiar with the contemporaries A more profound study on the oriental embroidery will supply a great deal of material and ideas to the fashion industry. Moreover, an effort to raise self-pride in traditional culture will be also in need.

칠성화(七星畵)의 그래픽체계 분석 (Graphic system analysis on the Chil Sung Hwa(seven stars picture))

  • 나윤화
    • 디자인학연구
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    • 제11권
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    • pp.22-29
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    • 1995
  • 본 논문에서는 시각 조형적인 입장에서의 '칠성 화(七星畵)'를 대한(大韓)민족 고유의 시각전달체계의 한 심벌(symbol)로서 이해하였다. 또한 그것에 대한 그래픽분석을 통해 토속적인 민족의 정서를 단순하고 그래픽한 선과 색채로써 수학적인 그리드(grid)안에 규격있게 표현하였음을 분석하였다. 이에 칠성 화를 조상의 시각 조형물로서 커뮤니케이션 디자인의 한 분야로 정착시키는 데 기여하고자 함이 본 연구의 주된 목적이다. 이에 그래픽 측면 구조분석의 구체적 내용을 요약하면 1) 동양의 수학적 사고와 공간 구성은 기본적으로 동양의 공(空)과 허(虛)로 일컬어지는 0(zero)의 개념과 수학의 무한(無限)의 수(數)개념을 설명하였으며, 이것을 근거로 음양론(陰陽論)을 기초로 한 대칭 개념의 발전으로 대각선 전개 법을 유추하여 방위개념에 의거한 공간분할 방식을 설명하였다. 2) 비례분석에서는 황금 분할비 구형을 기준하여 현대적 레이아웃에 있어 시각중심 위치를 잡고 분석하였는데 이에 칠성화의 존상(尊像)의 미간중심을 그 비례 중심적으로 지정하였다. 3) 수학적 구조 분석은 균형있는 배열 및 그 형태법칙에 어떠한 통일된 원칙을 찾기 위한 방법으로 황금 분할 비에 의거하여 분할한 그리드를 적용시켜 그 위에 주(主)인물과 부(副)인물의 기본적인 움직임에 인체모듈(module)에 기준한 형태법칙을 유추 분석하였다. 이에 칠성화의 경우 만다라(曼茶羅) 도형의 기본 분할 방법과 그 맥을 같이 하여 두 가지 유형으로 분석하였다.

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위완통(胃脘痛)의 임상변증(臨床辨證)과 위내시경(胃內視鏡) 미관변증(微觀辨證)의 관계(關係)에 대한 증례(證例) 연구(硏究) (Case Study for the Relation between Clinical Bian Zheng and Gastroscopic Bian Zheng of Epigastric Pain)

  • 고수미;문석재;문구
    • 대한한의학회지
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    • 제17권1호
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    • pp.266-279
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    • 1996
  • To complement and develop the Orient Medical Bian Zheng treatmemt(韓方辨證施治), I have observed and analysed 68 persons who have recieved medical treatment because of the epigastric pain. Considering and analysed the Clinical Diagnosis(臨床診斷) and Clinical Bian Zheng(臨床辨證), Clinical Diagnosis(臨床診斷) and Gastroscopic Bian Zheng(微觀辨證), Clinical Bian Zheng(臨床辨證) and Gastroscopic Bian Zheng(微觀辨證), case history, age and sex, I have obtained the conclusion as follows. 1. The frequency of epigastric pain according to the classfication of Clinical Bian Zheng(臨床辨證) most occured in Gi Che Zheng(氣滯證), then in Huh Han Zheng(虛寒證). and least in Wi Youl Zheng. 2. There is no clear connection between the Clinical Bian Zheng(臨床辨證) and Clinical Diagnosis(臨床診斷). 3. The frequency of the epigastric pain according to Gastroscopic Bian Zheng(微觀辨證), mainly occurred in Wi youl Type(胃熱型), Wi Rac Jac Sang Type(胃絡灼傷滯型)and then occurred in Wi Han Type(胃寒型), and least occurred in Wi Rac A Che Type(胃絡瘀滯型) 4. Having observed the relation between the Gastroscopicin Bian Zheng(微觀辨證), and Clinical Diagnosis(臨床診斷) as pathological process, I have obtained the result that Wi Youl type(胃熱型) and Wi Rac Jac Sang Type(胃絡灼傷型) mainly occurred in Erosive Gastritis and Superficial Gastritis at the early stage, and Wi Rac A Che Type(胃絡瘀滯型) occurred in the whole stage among the Wuperficial Gastritis, Atro pic Gastritis, and Erosive Gastritis, Gastric Cancer, and the Wi Han Type(胃寒型) mainly occurred in Atropic Gastritis at the later stage. 5. The relation between Clinical Bian Zheng(臨床辨證) and Gastroscopic Bian Zheng(微觀辨證) do not coincide. 6. Observing the relation between the Clinical Bian Zheng(臨床辨證) and case history, Gi Che Zheng(氣滯證), Huh Han Zheng(虛寒證), Wi Youl Zheng(胃熱證) were commonly seen in the early stage of the case history, and Eum Huh Zheng(陰虛證) and Houl A Zheng(血瘀證) were seen in every stage. 7. Observing the relation between the Clinical Bian Zheng(臨床辨證) and age, Gi Che Type(氣滯型) was mostly seen in the thirties and other Bian Zheng(辨證) was seen after the middle 8. Observing the relation between the Clinical Bian Zheng(臨床辨證) and sex, Gi Che Type(氣滯型) was seen at high ratio in both sexes. 9. Observing the relation between the Gastroscopic Bian Zheng(微觀辨證) and case history Wi Han Type(胃寒證), Wi Youl Type(胃熱型), Wi Rac Jac Sang Type(胃絡灼傷型) were seen in the early stage of the case history Wi Rac A Che Type(胃絡瘀滯型) was mostly seen in the later stage. 10. There was no clear connection between the Gastroscopic Bian Zheng(微觀辨證) and age, sex. Although the examples were not sufficient, recipe regarding the partial variation state of stomach mucos together with Orient Medical Bian Zheng(韓方辨證) treatment seems to be useful in the effective treatment of Bi wi(脾胃) disease besides the epigastric pain.

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독일목록규칙의 기본기입선정에 관한 연구 (A Study on the Choice of Main Entry in German Cataloging Rules; a comparison with the title entry in the Orient)

  • 김태수
    • 한국문헌정보학회지
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    • 제21권
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    • pp.61-101
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    • 1991
  • This study reviews the development and change of main entry principle in German cataloging codes, with special emphasis on RAK. With rerard to the functions of catalog, comparison between the traditional title main entry in the Orient and author main entry in the West has been made. The analysis confirms in this study that various criteria in choice of the entries in RAK have been adopted. In case of works where the persons who have played different roles in the works are named on the title page, as well as related works and works of mixed responsibility, the criteria of entry determination are complex and time consuming process and have no absolute value. And there are also various kinds of problems in corporate entries including confirmation of originator(Urheber), choice of either the territorial authority corncerned or corporate bodies as an entry depending on the nature of the publications, and a unique bibliographical situation of treaties. This means the code is absence of absolute value in selecting entries, and this results in adoption of main entry principle which has lost its significance for the purpose of cataloging. With emergence of the ISBD and actualization of automated cataloging, morever, all entries are equal as points of access. It would eliminate the need for personal judgements required in choice of main entry by the present code. In doing so, it would bring uniformity and standardization to cataloging practice. In direct approach to works, title entry is more developed finding device than author entry in cataloging theories. Thus introduction of unit card system beginning with title which is adopted in KCR3 would be desirable, the complicated rules for the choice of entry could be abandoned from cataloging codes. Most of the user studies show that catalog users have placed higher value on the title entry as a finding device and each entry is equal as access points through unit entry. This means that choice of a given entry as a main entry is unnecessary in cataloging codes. Title entry would be a rather simple standard and direct approach for works. This study proves that the traditional title entry of Korea is superior to author main entry in the Western world in cataloging theory. Thus recommendation to be made is that abandonment of author main entry from cataloging codes should be considered in the future.

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