• Title/Summary/Keyword: organic method

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Development of a GC-MS Diagnostic Method with Computer-aided Automatic Interpretation for Metabolic Disorders (GC-MS 크로마토그램의 컴퓨터 자동해석을 이용한 유전성 대사질환의 진단법 개발)

  • Yoon, Hye-Ran
    • Journal of The Korean Society of Inherited Metabolic disease
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    • v.6 no.1
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    • pp.40-51
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    • 2006
  • Purpose: A personal computer-based system was developed for automated metabolic profiling of organic aciduria and aminoacidopathy by gas chromatography-mass spectrometry and data interpretation for the diagnosis of metabolic disorders Methods: For automatic data profiling and interpretation, we compiled retention time, two target ions and their intensity ratio for 77 organic acids and 13 amino acids metabolites. Metabolites above the cut-off values were flagged as abnormal compounds. The data interpretation was a based on combination of flagged metabolites. Diagnostic or index metabolites were categorized into three groups, "and", "or" and "NO" compiled for each disorder to improve the specificity of the diagnosis. Groups "and" and "or" comprised essential and optional compounds, respectively, to reach a specific diagnosis. Group "NO" comprised metabolites that must be absent to make a definite diagnosis. We tested this system by analyzing patients with confirmed Propionic aciduria and others. Results: In all cases, the diagnostic metabolites were identified and correct diagnosis was founded to be made among the possible disease suggested by the system. Conclusion: The study showed that the developed method could be the method of choices in rapid, sensitive and simultaneous screening for organic aciduria and amino acidopathy with this simplified automated system.

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Characterization of Volatile Organic Compounds associated with Environmental Tobacco Smoke

  • Baek, Sung-Ok;Roger A. Jenkins
    • Journal of Korean Society for Atmospheric Environment
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    • v.14 no.E
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    • pp.41-58
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    • 1998
  • In this study, a wide range of volatile organic constituents of environmental tobacco smoke (ETS) were determined using an environmental chamber, where ETS is the sole source of target compounds. ETS was generated in an environmental chamber by a number of different cigarettes, including the Kentucky reference cigarette and eight different commercial brands. More than 30 compounds were measured simultaneously for a total of twelve experimental runs. The target compounds are classified into three major classes, i.e. vapor phase ETS markers including 3-ethnylpyridine (3-EP) and nicotine, carbonyl compounds including formaldehyde, and volatile organic compounds (VOCs). The results from the chamber study were used to generate characterized ratios of selected VOCs to 3-EP, a vapor phase ETS marker. Emission factors for VOCs associated with ETS were also estimated. The characteristic ratios appeared to be generally in good agreement with published data obtained by environmental chamber studies similar to this study. This implies that the ratios may be useful for identifying and quantifying the impact of ETS as a source of target compounds in 'real world' indoor environments, which is affected by a complex mixture of multi-sources. The environmental chamber method described here provides a direct and reliable method to compare the ETS generated by different cigarettes. The method can also be applied to the simultaneous determination of many different ETS components.

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Organic Light Emitting Diodes (OLED) with Electrostatic spray deposition (ESD)

  • Hwang, Won-Tae;Kim, Nam-Hun;Xin, Guoqing;Jang, Hae-Gyu;Chae, Hee-Yeop
    • Proceedings of the Korean Vacuum Society Conference
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    • 2010.02a
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    • pp.432-432
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    • 2010
  • Organic light emitting diodes (OLED) thin films were fabricated by Electrostatic spray deposition (ESD). In this study, we reported the thickness, morphology, current efficiency, luminescence of OLED fabricated by ESD. These results were compared with the spin coating method, and showed that also ESD is a good fabrication method for OLED because of its characteristics similar with the results using spin coating. The active layer consists of organic blends with Poly(N-vinylcarbazole) (PVK), 2-(4-Biphenyl)-5-(4-tert-butylphenyl)-1,3,4-oxadiazole (PBD), N,N'-Bis(3-methylphenyl) -N,N'-bis(phenyl)-benzidine (TPD), Tris(2-phenylpyridine)iridium(III) (Ir(ppy)3), and the structure of OLED consists of aluminum (Al), lithium fluoride (LiF), organic blends, PEDOT:PSS and Indium-tin-oxide (ITO), which was used as the top cathode, cathode interfacial layer, emitting layer and bottom anode, respectively. The results suggest that Electrostatic spray deposition is a promising method for the next generation of OLED fabrication since it has a probability fabricating large-area thin films.

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Measurement of Thermo-physical Properties of Organic Phase Change Materials using Modified T-history Method (수정된 T-history 법을 이용한 유기 상전이 물질들의 열 물성 측정)

  • Dao, Van-Duong;Choi, Hong-Ki;Choi, Ho-Suk;Oh, Jun-Taek;Kim, Jong-Kuk
    • Korean Chemical Engineering Research
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    • v.48 no.1
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    • pp.93-97
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    • 2010
  • In this study, we have measured the thermo-physical properties of pure organic phase change materials (PCMs) and their mixtures which have the melting points from 0 to $15^{\circ}C$ by using a modified T-history method. These organic PCMs can be used as coolant materials for packaging and shipping of vaccines. Through measuring the thermophysical properties of pure paraffins, we were able to know that we could improve the reliability of measurement if we considered the melting point of each material and subsequently decided an optimum coolant temperature for each system. The modified T-history method showed a potential usefulness for reliably measuring thermo-physical properties of organic mixtures with avoiding possible inaccuracy of measurement due to using a small amount of sample at DSC measurement.

RESEARCH ON MANAGEMENT AND ECONOMIC IN ALTERNATIVE AGRICULTURE IN THE UNITED STATES OF AMERICA (미국 대체농업의 경영 및 경제적인 연구)

  • 김종무
    • Korean Journal of Organic Agriculture
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    • v.2 no.1
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    • pp.16-23
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    • 1993
  • The traditional farming method has very long history in the process of agricultural development. The application of chemical fertilizers production became most popular to increase quantities of agricultural production. The United States of America is one of largest countries in the world. There are at present 50 States and farming conditions are very different from each individual States. There are increasing trend of agricultural production by applying chemical fertilizers as well as sprays during last 50 years(1940-90). The disadvantages of conventional farming method were to destroy nature and human life. There were some other kinds of disadvantages such as nitriated contamination in drinking water both for human being and animals. The alternative farming method is one of new farming method reducing and/of non-application of chemical fertilizers and sprays in agricultural production. There is less economic research on alternative farming system about $5.444 economic advatages in organic farms comparing commercial farms at the same area. There are advantage of higher unit price level in orgnic products, decreasing chemical costs as well as effect of crop combinations. It is certainly necessary to have more empirical research on economic and management of alternative farming method in the United States of America. However, if there is economic advantage in alternative farming methods, the future development possibility of alternative farming method can be very bright in vear future. There might be more advantages such as soil conservation, better quality of agricultural products, better health conditions of farmer's and consumer's as well as keeping healthy environment of rural and urban areas.

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A Study on Application Test of Cut-slope Revegetation Measures with Organic Soil Amendment Materials (유기질계 토양개량재를 이용한 절토비탈면 녹화공법 적용시험 연구)

  • Jeon, Gi-Seong;Woo, Kyung-Jin
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.8 no.3
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    • pp.13-20
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    • 2005
  • This study was conducted to suggest the ecological restoration methods of the decomposed granite cut-slope by organic soil amendment materials. Field test carried out for the cut-slope with organic soil amendment materials method and other three revegetation methods in Cheongwon. Test revegetation plants were Festuca arundinacea, Lolium perenne, Dactylis glomerata, Lespedeza cyrtobotrya, and Arundinella hirta. The result of this study can be summarized as follows; 1. The soil hardness, the soil acidity, and the soil humidity of organic soil amendment materials method were at a suitable value for plants growth. And it was better as compared with other three revegetation methods of cutting-rock slopes. 2. The result of toxic substance investigation, all items were at a suitable for standard law. 3. During one year after seeding, most plants germinated and especially Festuca arundinacea and Dactylis glomerata grows well. Seedling numbers were 336.7 per $m^2$(after 6 months), 183.3 per $m^2$(after 10 months), and 353.3 per $m^2$(after 6 months). Ten months later after seeding, plants showed 80% ground coverage. Visual rate, plant height, and growth rate were excellence, Also, high plant growth in spring better than autumn.

A Study on the thermal and electrical stability of PVDF organic thin films fabricated by physical vapor deposition method. (진공증착법을 이용하여 제조한 PVDF 유기 박막의 열적.전기적 안정 특성에 관한 연구)

  • 박수홍;이덕출
    • Journal of the Korean Vacuum Society
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    • v.8 no.2
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    • pp.93-101
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    • 1999
  • The purposed of this paper is to investigate the electrical and thermal stability of Polyvinylidene fluoride(PVDF) organic thin films prepared by the vapor deposition method. The differential scanning calorimetry curve of the PVDF organic thin films prepared by increasing substrate temperature showed that the melting curve increased from $128^{\circ}C$ to $142^{\circ}C$. This result implied that the PVDF organic thin film prepared by increasing substrate temperature increased intermolecular force in the crystalline region. The anomalous properties in dielectric constant and dielectric loss at low frequency and high temperature were described for PVDF organic thin film containing impurity carriers. It was confirmed that in view of electric conductive characteristics the ohm's law is satisfied in the range of lower electric field and ln J was proportional to the electric field ln E as like the conventional property of ionic conduction in the range of higher electric field. It was confirmed that major carrier of conductivity was ions. The electrical stability was improved according to an increase of the substrate temperature. On the basis of this experimental result, it could be observed that the optimum temperature of substrate for the electrical and thermal stability was at $105^{\circ}C$.

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Speciation of Arsenic from Soil Organic Matter in Abandoned Gold and Silver Mines, Korea

  • Ko, Il-Won;Kim, Kyoung-Woong;Hur, Hor-Gil
    • Journal of Applied Biological Chemistry
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    • v.51 no.1
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    • pp.36-44
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    • 2008
  • Organic forms of arsenic (As) were determined through fractionation procedure of soil organic matter (SOM) in soil, sediments and mine tailing samples from the Myungbong, Dongil, and Okdong mining areas of southern Korea. An alkaline extraction method was applied to soil samples followed by the fractionation procedures of SOM by the DAX-8 and XAD-4 resin adsorption method. Major fraction of organic As species (42% to 98%) was found in acid-soluble fraction, whereas minor fraction (0.1 % to 67.8%) was present in the humic-associated As. In acid-soluble fractions, the transphillic- and hydrophilic-associated As were dominant in addition to As binding with humic and fulvic SOM. Arsenic binding was the strongest between pH 6 to 8 and reduced to about 70% at both low and high pH regions. The amount of both transphillic and hydrophillic associated As was less changed than humic and fulvic-associated As, in both low and high pH regions. This apparently indicates that As has stronger affinity towards hydrophillic rather than hydrophobic organics. From the experimental observation of As-binding SOM in natural soil, the ligand exchange model may be a feasible explanation of transphillic and hydrophillic affinity of As.

A Study on Characteristics of Self-Contained Three-Dimensional Organic Body found in Architecture of Ito Toyo (이토 토요의 건축에 나타난 자기완결적 3차원 조직체의 특성에 관한 연구)

  • Kim, Jong-Jin
    • Korean Institute of Interior Design Journal
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    • v.26 no.2
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    • pp.55-63
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    • 2017
  • Recent projects of Japanese architect, Ito Toyo have been evolved into innovative and experimental stages that are unique and different from other contemporary architects. Since Ito established his own office in 1971, there were several critical changes and developments in terms of architectural philosophy as well as design methods. Particularly, after Sendai Mediatheque, Ito has tended to focus on creating three-dimensional organic body in which architectural form, space, structure, facilities, images are merged all together. With this new type of three-dimensional structure, Ito aims to generate a new notion of architecture as 'living organism'. This paper tried to analyze Ito's new concept of architecture, design process of three-dimensional organic body and its ultimate characteristics and meanings. For the analysis, three projects were selected: Taichung Metropolitan Opera House(2005), Berkeley Art Museum and Pacific Film Archive(2007), The New Deichman Library in Oslo(2008). These projects clearly represent several types of three-dimensional organic body. After the comparative studies, it is found that, in Ito's design process and method, there are unique characters: ambivalent relationship between plan and three-dimensional form, aiming new/hyper reality through complicated collaboration of analogue and digital design tools, and contradictory relationship with surrounding urban context. Although there are some limitations and restrictions, ever-evolving Ito's design concept and methods are very much valid and meaningful in contemporary spatial design in various perspectives.

Box Cathode Sputtering Technologies for Organic-based Optoelectronics (유기물 광전소자 제작을 위한 박스 캐소드 스퍼터 기술)

  • Kim, Han-Ki
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.19 no.4
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    • pp.373-378
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    • 2006
  • We report on plasma damage free-sputtering technologies for organic light emitting diodes (OLEDs), organic thin film transistor (OTFT) and flexible displays by using a box cathode sputtering (BCS) method. Specially designed BCS system has two facing targets generating high magnetic fields ideally entering and leaving the targets, perpendicularly. This target geometry allows the formation of high-density plasma between targets and enables us to realize plasma damage free sputtering on organic layer without protection layer against plasma. The OLED with Al cathode prepared by BCS shows electrical and optical characteristics comparable to OLED with thermally evaporated Mg-Ag cathode. It was found that OLED with Al cathode layer prepared by BCS has much lower leakage current density ($1{\times}10^{-5}\;mA/cm^2$ at -6 V) than that $(1{\times}10^{-2}{\sim}-10^0\;mA/cm^2)$ of OLED prepared by conventional DC sputtering system. This indicates that BCS technique is a promising electrode deposition method for substituting conventional thermal evaporation and DC/RF sputtering in fabrication process of organic based optoelectronics.