• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• v.25 no.3
• /
• pp.163-179
• /
• 2022

Although functional gastrointestinal disorders (FGIDs) are very common in pediatric patients, there is a scarcity of published epidemiologic data, characteristics, and management patterns from Saudi Arabia, which is the 2nd largest Arabic country in terms of area and the 6th largest Arabic country in terms of population, with 10% of its population aged <5 years. Functional constipation (FC) is an FGID that has shown a rising prevalence among Saudi infants and children in the last few years, which urges us to update our clinical practices. Nine pediatric consultants attended two advisory board meetings to discuss and address current challenges, provide solutions, and reach a Saudi national consensus for the management of pediatric constipation. The pediatric consultants agreed that pediatricians should pay attention to any alarming signs (red flags) found during history taking or physical examinations. They also agreed that the Rome IV criteria are the gold standard for the diagnosis of pediatric FC. Different therapeutic options are available for pediatric patients with FC. Dietary treatment is recommended for infants with constipation for up to six months of age. When non-pharmacological interventions fail to improve FC symptoms, pharmacological treatment with laxatives is indicated. First, the treatment is aimed at disimpaction to remove fecal masses. This is achieved by administering a high dose of oral polyethylene glycol (PEG) or lactulose for a few days. Subsequently, maintenance therapy with PEG should be initiated to prevent the re-accumulation of feces. In addition to PEG, several other options may be used, such as Mg-rich formulas or stimulant laxatives. However, rectal enemas and suppositories are usually reserved for cases that require acute pain relief. In contrast, infant formulas that contain prebiotics or probiotics have not been shown to be effective in infant constipation, while the use of partially hydrolyzed formula is inconclusive. These clinical practice recommendations are intended to be adopted by pediatricians and primary care physicians across Saudi Arabia.

• Journal of the Korean Academy of Esthetic Dentistry
• /
• v.31 no.1
• /
• pp.11-18
• /
• 2022

Adult patients who need implant and prosthodontic treatment often need treatment to improve the existing occlusion through orthodontic treatment for long-term stable treatment results. However, due to non-aesthetic and uncomfortable orthodontic treatment with orthodontic brackets and wires, many adult patients give up treatment even though they know the need for it. Recently, as digital dentistry has affected all areas of dentistry, clear aligner orthodontic systems have begun to be widely used, and their use is increasing in adults and old-aged people due to the esthetic advantage and convenient oral care. SERAFIN clear aligner system developed in Korea has been developed with the aim of implementing a functional occlusion harmony and is used not only for partial orthodontic treatment but also comprehensive orthodontic treatment. This patient presentation is shown the treatment using SERAFIN clear aligner system for the treatment of patient with TMD, severe extrusion of maxillary second molars, and extracted teeth.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
• /
• v.36 no.3
• /
• pp.42-73
• /
• 2023

Objectives : In order to investigate the current status of recent clinical evidence related to complementary and alternative medicine(CAM) treatment for burns and to inform research and treatment strategies for future, we publish a scoping review(ScR) of randomized controlled trials(RCTs). Methods : The research question of the ScR was "Are there any RCTs of CAM treatment for burn?". RCTs published from 2000 to 2022 were identified in 7 databases(PubMed, Cochrane, CNKI, OASIS, RISS, KCI, KMbase) in March 2023. Data were tabulated and analyzed descriptively with respect to the research questions. Results : 41 RCTs were included. 21(51.2%) were conducted in China, 13(31.7%) in Iran. The main treatment criteria were herbal medicine in 28 cases, acupuncture in 9 cases, chuna therapy in 4 cases, and psychotherapy in 3 cases. Among the herbal medicine, there were 19 topical medications, 5 injections(intravenous pharmacopuncture), 4 aerosol drugs(aromatherapy), and 1 oral drug. Among the acupuncture, there were 4 plum blossom needles(seven-star needles), 2 wrist-ankle acupunctures, 2 press needles, and 1 electroacupuncture. CAM treatments were effective in treating burns. It reduced pain and pruritus at the burn site, helped recovery and management of the donor site, reduced anxiety and pain during dressing change, improved hematological problems and vital signs, and finally lowered the mortality rate. CAM treatments also lowered health care costs. Conclusions : CAM treatments for burns is prospective, and that it deserves to make high-quality studies including additional large-scale RCTs.

• The Korea Journal of Herbology
• /
• v.24 no.4
• /
• pp.127-135
• /
• 2009

Objectives : Gagam-Gongjin-dan (GGD) composited with Cervi parvum Cornu, Corni Fructus, Angelica gigantis Radix, Lycii Fructus, Dioscoreae Rhizoma, Citri Pericarpium, Gastrodiae Rihzoma, Agastachis Herba, Cassiae cortkex, Scutellariae Radix, Schisandrae Fructus has been traditionally used for chronic diseases or weakness after illness in oriental countries. However, little is known about the effects of methanol extract of GGD on immune responses to ovalbumin (OVA) plus alum. Therefore, the purpose of this study was to investigate the effects of GGD on immune responses to ovalbumin plus alum in Balb/c mice. Methods : In this study, the extract of GGD was prepared by extracting with methanol for 7 days. The extract was freeze-dried following filtration through vacuum distillation system. Mice were orally administrated with or without GGD extract of different doses (50-200 mg/kg/day) for 30 days. We examined the effects of GGD extract on the serum levels of total IgE, OVA-specific IgE, IgG1, IgG2a, and CTACK/CCL27 production and CCR10 expression in lymph node cells and body weight change and foot pad swelling responses in ovalbumin treated Balb/c. Results : The oral administration of GGD dose-dependently reduced the serum levels of total IgE, OVA-specific immunoglobulin (IgE, IgG1 and IgG2b) and CTACK/CCL27 production in ovalbumin treated BALB/c mice. The levels of CCR10 expression from lymph node cells of OVA treated mice were markedly suppressed by treatment with GGD in a concentration dependent manner. Furthermore, foot pad swelling responses were also markedly suppressed by GGD. However, body weight were significantly increased dose dependently by GGD treatment. Conclusions : These results suggest that GGD treatment suppresses immune responses to ovalbumin, and these properties may contribute to allergic disease care.

• Journal of Chest Surgery
• /
• v.57 no.1
• /
• pp.62-69
• /
• 2024

Background: Cervical esophageal cancer is a rare malignancy that requires specialized care. While definitive chemoradiation is the standard treatment approach, surgery remains a valuable option for certain patients. This study examined the surgical outcomes of patients with cervical esophageal cancer. Methods: The study involved a retrospective review and analysis of 24 patients with cervical esophageal cancer. These patients underwent surgical resection between September 1994 and December 2018. Results: The mean age of the patients was 61.0±10.2 years, and 22 (91.7%) of them were male. Furthermore, 21 patients (87.5%) had T3 or T4 tumors, and 11 (45.8%) exhibited lymph node metastasis. Gastric pull-up with esophagectomy was performed for 19 patients (79.2%), while 5 (20.8%) underwent free jejunal graft with cervical esophagectomy. The 30-day operative mortality rate was 8.3%. During the follow-up period, complications included leakage at the anastomotic site in 9 cases (37.5%) and graft necrosis of the gastric conduit in 1 case. Progression to oral feeding was achieved in 20 patients (83.3%). Fifteen patients (62.5%) displayed tumor recurrence. The median time from surgery to recurrence was 10.5 months, and the 1-year recurrence rate was 73.3%. The 1-year and 3-year survival rates were 75% and 33.3%, respectively, with a median survival period of 17 months. Conclusion: Patients with cervical esophageal cancer who underwent surgical resection faced unfavorable outcomes and relatively poor survival. The selection of cases and decision to proceed with surgery should be made cautiously, considering the risk of severe complications.

• Korean Journal of Psychosomatic Medicine
• /
• v.32 no.1
• /
• pp.1-9
• /
• 2024

Frailty is a clinical syndrome as an increased vulnerability to stressors, leading to a decrease in physiologic reserves and a decline in the ability to maintain a good homeostasis. This condition leads to an increased risk of hospitalization, disability and mortality. Frailty occurs due to various causes and requires a multidimensional approach. It is also important to detect and manage it early. Frailty is also deeply related to neuropsychiatric problems such as pain and depression. In evaluating frailty, it is desirable to comprehensively consider not only physical areas such as disease, nutrition, movement, and sensory functions, but also psychosocial areas, and representative scales include Fried's physical frailty phenotype and Rockwood's frailty index. Physical activity and appropriate protein intake are important for frailty management, and inappropriate drug use should be reduced and oral care, cognitive function, and falls should also be noted. Frailty and pain can affect each other, and pain can promote frailty. Evidence has been published that hormone and protein abnormalities, immune system activity and inflammatory response, and epigenetic mechanisms work in common in the field of frailty and pain. More extensive and high-quality research should be conducted in the future, and the quality of life will be improved if the results are applied to the suppression and treatment of old age and pain.

• The Journal of Korean Medicine
• /
• v.44 no.4
• /
• pp.41-58
• /
• 2023

Objectives: This retrospective observational study aimed to investigate the efficacy and safety of Cheongpebaedok-tang, a traditional Korean herbal medicine, provided via telemedicine to patients with asymptomatic to mild COVID-19 in Korea. Methods: From February to April 2020, a retrospective analysis investigated COVID-19 patients treated via Korean telemedicine. The study involved asymptomatic to mild cases receiving Cheongpebaedok-tang more than three times, along with continuous Korean medicine care in convalescence. Diagnoses and treatment adhered to the telemedicine guidelines of the Association of Korean Medicine, with varied Cheongpebaedok-tang prescriptions based on symptom severity. Symptom evaluation involved a detailed assessment using a 15-item tool at initial and final sessions. Results: The study included 27 patients, with a mean age of 48.7 ± 2.3 years (mean ± standard error). Patients began self-administering oral Cheongpebaedok-tang for an average of 19.4 ± 1.8 days after the date of COVID-19 diagnosis confirmation and continued the medication for 15.8 ± 1.2 days. The reported side effects of the Cheongpebaedok-tang included palpitations (11.1%), insomnia (7.4%), dizziness (3.7%), and diarrhea (3.7%). All side effects disappeared after adjusting the prescription according to standard treatment guidelines. The occurrence of all COVID-19-related adverse symptoms, except fatigue and myalgia, decreased. Fatigue was the most common chronic symptom persisting after 6 months (51.9%), followed by ocular symptoms (37.0%) and sore throat (22.2%). Conclusions: This study implies Cheongpebaedok-tang may offer a potentially safe, symptom-alleviating approach for managing mild COVID-19 cases via telemedicine, although further comprehensive research is warranted.

• Journal of dental hygiene science
• /
• v.6 no.3
• /
• pp.219-225
• /
• 2006

As the number of old people grows in today's modern society, dental hygienist's role is more emphasized than ever before for oral hygiene management of the aged. It is also important to find out college students' knowledge, attitude and behavior towards the elderly. Therefore, this study is conducted through interview with college students who are majoring in dental hygiene of health care in Busan and will be in charge of oral hygiene. According to the interview, this study obtains the following results: 1. The level of undergraduate students' knowledge of old people shows a total score of $14.53{\pm}2.35$ (correct response rate is 69.9%). 2. The average score of undergraduate students' attitude towards old people is in a neutral range(50~70), recording 63.12(${\pm}7.22$) on a scale of 100. 3. The average score of undergraduate students' behavior towards old people is lower than a neutral range(43~60), recording 39.09(${\pm}13.43$) on a scale of 85 and showing negative behavior. 4. Experience of living together with the elderly and participating in volunteer jobs lead to significant differences in undergraduate students' attitude towards old people. 5. Experience of living together with the elderly causes significant differences in undergraduate students' behavior towards old people. That is, undergraduate students living together with the elderly show a positive behavior towards old people. 6. Undergraduate students' knowledge shows a strong positive relationship with their attitude, but it has a bit positive correlation with behavior even though there are no statistically significant differences between knowledge and behavior. No relationship is found between behavior and attitude. That is, undergraduate students have more positive attitude as their knowledge of the elderly is higher, but their behavior is not positive.

• The Journal of Korean society of community based occupational therapy
• /
• v.10 no.1
• /
• pp.31-38
• /
• 2020

Objective : The purpose of this study is to investigate the effects of bilateral chewing exercise applied for 6 weeks on occlusion force and masseter muscle thickness in the elderly living in the community. Methods : This study recruited 25 community residents. All participants performed bilateral chewing exercise using equipment developed for the purpose of oral chewing exercise. The chewing exercise was divided into isometric and isotonic type and applied for about 20 minutes a day, five times a week for six weeks. For the evaluation, the masseter muscle thickness and the maximum occlusion force were measured three times at three week intervals using a portable ultrasound instrument and an occlusion force gauge. Results : As a result of the change in masseter muscle thickness, baseline, 3 weeks later, and 6 weeks later referred to 7.51±0.43, 7.63±0.44, and 7.83±0.46, respectively (F=3.819, p<.05). The post hoc test resulted in a significance between baseline and 6 weeks later (p=0.023). Similarly, as a result of the change in occlusion force, baseline, 3 weeks later, and 6 weeks later referred to 265±9.22, 268±9.57, and 271.59±10.16, respectively (F=3.031, p<.05). The post hoc test resulted in a significance between baseline and 6 weeks later (p=0.048). Conclusion : This study confirmed that bilateral chewing exercise was effective for increasing masseter muscle thickness and occlusion force in the elderly. Therefore, bilateral chewing exercise can be applied as a therapeutic exercise method for improving oral function.

• Korean Journal of Health Education and Promotion
• /
• v.10 no.1
• /
• pp.34-60
• /
• 1993

This study was done for the improvement of dental health of rural villagers and the dental health education, through finding of the types of brushing teeth and dental treatment of 812 people in Sunsan, Kyungpook province for 35days from March 27 to April 30 in 1992. Summaries are as follows ; 1. 58.5 percent of respondents were women, 56.3 percent were 40′s, 28.0 percent were 30′s, 12.3 percent were 50′s, and the over 60′s were 3.4 percent Elementary school graduates were 36.1 percent and most of them were middle school graduates, 33.5 percent. In view of the occupation, farmers were 56.5 percent, factory workers were 17.9 percent, the middle class (monthly pay amounting to 500,000∼990,000 won) were 49 percent and the lower class(less than 500,000 won) were 30.9 percent. In the standpoint of religion, Buddhists were 42.5 percent. 2. In the number and times of respondents brushing, 35.5 percent is "after dinner", 25.6 percent is "Before going to bed", 15.8 percent is "After breakfast", 13.3 percent is "After every meal", 5.2 percent is "Before breakfast" and 4.7 percent is "The sometimes it occurs to them". 3. The acquirement process of knowledge on the dental health were clinics or health center dentists (27.6%), TV(24.5%), magazine(9.2%), school(7.8%), relatives(5.3%). and 25.6 percent has never acquired. 28.3 percent of the farmers learned something by clinics and 28.1 percent of them haven′t heard about dental health. 4. The rate of persons who experienced oral diseases during 1 year period was 76.1 percent, and that of the educated was 19.9 percent and that of the uneducated 80.1 percent. The authorities concerned with treatment were dentist′s(41.6%), health center(30.3%), and the unlicensed person(2.9%). The rate of negligence was 6.3 percent, farmers experienced oral disease was 75.2 percent and they utilized the health center most often(36.2%). 5. The rate of person who had experienced dental prosthesis during ten year period was 71.9 percent, and the final place or man for dental prosthesis was dental clinic(59.4%), the unlicensed person(27.1%), and health center(13.5%). The rate of farmers experienced dental prosthesis was 70.4 percent. They utilized the dental clinic, the unlicensed person and the health center with the rates of 51.5 percent, 32.2 percent, and 16.7 percent respectively. 6. As to the results of dental prosthesis using the dental clinic, "being satisfied now" was 72.4 percent, "being dissatisfied" 14.4 percent, "being unable to use it" 3.1 percent, "its being somewhat usable" 10.1 percent, "having some problem" 38.7 percent, and "there being no problems" 61.3 percent. About utilizing the unlicensed person, "being satisfied now" was 65.8 percent, "being dissatisfied" was 10.7 percent, "being unable to use it" 5.1 percent and "its being some what usable" was 18.4 percent. 7. The rate of missing teeth holders amounted to 89.8 percent, the rate of the educated to the uneducated was 19.2 percent to 80.8 percent The reasons of neglecting that illness were due to "Endurable"(28.3%), and "No money" (24.3%). In the case of farmers 89.1 percent of them were the missing-teeth holders, the "Endurable" were 29.8 7. percent, and "No money" lay in 27.4 percent. 8. Their hopeful centers for dental prosthesis were the dental clinics(76.6%), and the health center(16.9%).