• Title/Summary/Keyword: optimized fit

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Optimization of POME treatment process using microalgae and ultrafiltration

  • Ibrahim, R.I.;Mohammad, A.W.;Wong, Z.H.
    • Membrane and Water Treatment
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    • v.6 no.4
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    • pp.293-308
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    • 2015
  • Palm oil mill effluent (POME) was produced in huge amounts in Malaysia, and if it discharged into the environment, it causes a serious problem regarding its high content of nutrients and high levels of COD and BOD concentrations. This study was devoted on POME treatment and purification using an integrated process consisting of microalgae treatment followed by membrane filtration. The main objective was to find the optimum conditions as retention time and pH in the biological treatment of POME. Since after the optimum conditions there is a diverse effect of time and the process become costly. According to our knowledge, there is no existing study optimized the retention time and percentage removal of nutrients for microalgae treatment of POME wastewater. In order to achieve with optimization, a second order polynomial model regression coefficients and goodness of fit results in removal percentages of ammonia nitrogen ($NH_3-N$), orthophosphorous ($PO_4{^{-3}}$), COD, TSS, and turbidity were estimated. WinQSB technique was used to optimize the objective function of the developed model, and the optimum conditions were found. Also, ultrafiltration membrane is useful for purification of POME samples as verified by experiments.

Optimization for the Post-Harvest Induction of trans-Resveratrol by Soaking Treatment in Raw Peanuts (침지조작에 의한 레스베라트롤 증가조건의 최적화)

  • Lee, Seon-Sook;Seo, Sun-Jung;Lee, Boo-Yong;Lee, Hee-Bong;Lee, Junsoo
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.4
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    • pp.567-571
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    • 2005
  • In this study, the effects of varying the amount of water, soaking time at $25^{\circ}C$ and drying time after soaking at $45^{\circ}C$ on the induction of resveratrol were evaluated to optimize the soaking treatment by response surface methodology (RSM). After response surface regression (RSREG), the second-order polynomial equation was fitted to the experimental data. The analysis of variance showed that the model appeared to be adequate $(R^2=0.9547)$ with no significant lack of fit (p>0.1). From statistical analysis, amount of water and soaking time were found to be significant factors. On the other hand, drying time was not significant. Ridge analysis showed that the optimized parameters were $67.15\%$ for amount of water, 19.58 hr for soaking time, 65.56 hr for drying time. It was confirmed that resveratrol content was increased from $0.1\;{\mu}g/g$ to $4.55\;{\mu}g/g$ under the optimized conditions. In addition, the experimental values at the optimized condition agreed with values predicted by ridge analysis. The analytical method validation parameters such as accuracy, precision, and specificity were calculated to ensure the method's validity.

Antecedents and Consequence of Job Engagement: Focused on Food & Beverage Departments at Super Deluxe Hotels in Seoul (직무열의의 선행요인 및 결과변수에 관한 연구: 서울소재 특 1급 호텔 식음료 부서를 중심으로)

  • Kwon, Young-Guk;Yoon, Hye-Hyun
    • Culinary science and hospitality research
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    • v.21 no.3
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    • pp.212-231
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    • 2015
  • This study aims to understand the relationships between antecedents (recognition, empowerment, fair rewards, procedural justice(PJ), perceived organizational support(POS) and consequence(turnover intention(TI) of job engagement in a super deluxe hotel's F&B departments. Based on a total of 402 useful samples obtained for the empirical research, this study reviewed reliability and fitness of the research model and verified total 6 hypotheses with through the use of the AMOS statistical program. The hypothesized relationships in the model were tested simultaneously by using a structural equation model(SEM). The proposed model provided an adequate fit to the data, ${\chi}^2=668.894$(p<.001), df=373, CMIN/DF=1.794, GFI=.901, AGFI=.877, NFI=.928, CFI=.967, RMSEA=.044. The model's fit, as indicated by these indexes, was deemed satisfactory, and thus provided a good basis for testing the hypothesized paths. The results show that recognition, empowerment, fair rewards, PJ, and POS had a positive significant influence on job engagement. In addition, job engagement had a negative significant influence on TI. Through this it was confirmed that an optimized organization(working) environment reduced employees' turnover intention by increasing their job engagement level. Therefore, it is suggested that F&B departments at super deluxe hotels design various internal marketing programs from the perspective of efficient human resource management. Implications and limitations, as well as future research directions are also discussed.

CoMSIA Analysis on The Inhibition Activity of PTP-1B with 3${\beta}$-Hydroxy-12-oleanen-28-oic Acid Analogues (3${\beta}$-Hydroxy-12-oleanen-28-oic Acid 유도체들의 PTP-1B저해활성에 대한 CoMSIA분석)

  • Kim, Sang-Jin;Chung, Young-Ho;Kim, Se-Gon;Sung, Nack-Do
    • Applied Biological Chemistry
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    • v.51 no.3
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    • pp.171-176
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    • 2008
  • The comparative molecular similarity indices analysis (CoMSIA) models between 3${\beta}$-Hydroxy-12-oleanen-28-oic acid (1-30) analogues as substrate molecule and their inhibitory activities ($pI_{50}$) against protein tyrosine phosphatase (PTP)-1B were derived and discussed quantitatively. Listing in order, the CoMFA>CoMSIA${\geq}$HQSAR>2D-QSAR model, these QSAR models had the better statistical values. The optimized CoMSIA F1 model at grid 3.0${\AA}$ had the best predictability and fitness ($q^2$=0.754 and $r^2$=0.976) by field fit alignment. The order of contribution ratio (%) of CoMSIA fields concerning the inhibitory activities was a H-bond acceptor (48.9%), steric field (25.8%) and hydrophobic field (25.4%), respectively. Therefore, the inhibitory activities of substrate molecules against PTP-1B were dependent upon H-bond acceptor field (A) of $R_4$-group. From the analytical results of CoMSIA contour maps, oleanolic acid derivatives will have better inhibition activities if $R_1$ group has H-bond acceptor disfavor, $R_3$group has steric disfavor and $R_4$ group has steric, hydrophobic, H-bond favor.

The Search of Pig Pheromonal Odorants for Biostimulation Control System Technologies: III. Comparative Molecular Field Analysis (CoMFA) on Binding Affinities between Ligands of 2-(Cyclohexyloxy) Tetrahydrofurane Derivatives and Porcine Odorant Binding Protein (생물학적 자극 통제 수단으로 활용하기 위한 돼지 페로몬성 냄새 물질의 탐색: III. 2-(Cyclohexyloxy) Tetrahydrofurane 유도체와 Porcine Odorant Binding Protein 사이의 결합 친화력에 관한 비교 분자장 분석)

  • Sung Nack-Do;Park Chang-Sik;Jung Hoon-Sung;Seong Min-Kyu
    • Reproductive and Developmental Biology
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    • v.30 no.1
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    • pp.13-19
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    • 2006
  • To search of new porcine pheromonal odorants for biostimulation control system technologies to improve reproductive efficiency in livestock species, the comparative molecular field analysis (CoMFA) for binding affinity constant $(p(Od)_{50})$ between porcine odorant binding protein (pOBP) and ligands of odorant 2-(cyclohexyloxy) tetrahydrofurane derivatives as substrate molecule was conducted and discussed. In the optimized CoMFA model AIV with chirality $(C_1'(R),\;C_2(S))$ in substrate molecule and atom based fit alignment (A) of odorants, the statistical results showed the best predictability of the binding affinities $(p(Od)_{50})$ based on the LOO cross-validated value $r^2_{cv}.\;(q^2=0.886)$ and non-cross-validated conventional coefficient $(r^2_{ncv}.=0.984)$. the binding affinity constants exhibited a good correlation with steric (40.8%), electrostatic (14.6%) and hydrophobic (44.6%) factors of the substrate molecules. from the analytical results of the contour maps, which may give us some valuable informations to the modification of odorants for effective binding affinity.

The Search of Pig Pheromonal Ordorants for Biostimulation Control System Technology: IV. Comparative Molecular Similarity Indices Analyses (CoMSIA) on the Binding Affinities between Ligands of 2-(Cyclohexyloxy)-tetrahydrofurane Derivatives and Porcine Ordorant Binding Protein (생물학적 자극 통제 수단으로 활용하기 위한 돼지 페로몬성 냄새 물질의 탐색: IV. 2-(Cyclohexyloxy)tetrahydrofurane 유도체와 Porcine Odorant Binding Protein 사이의 결합 친화력에 관한 비교분자 유사성 지수분석(CoMSIA))

  • Sung, Nack-Do;Park, Chang-Sik;Jang, Seok-Chan;Choi, Kyung-Seob
    • Reproductive and Developmental Biology
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    • v.30 no.3
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    • pp.169-174
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    • 2006
  • To search of a new porcine pheromonal odorants, the comparative molecular similarity indices analysis(CoMSIA) between porcine odorant binding protein(pOBP) as receptor and ligands of green odorants 2-(Cyclohexyloxy)tetrahydrofurane derivatives as substrate molecule were conducted and disscused quantitatively. In the optimized CoMSIA model(I-AI) with chirality($I:\;C_{1'}(R),\;C_2(S)$) in substrate molecules and atom based fit alignment(AE) of the odorants the statistical PLS results showed the best predictability of the binding affinities based on the LOO cross-validated value ${r^2}_{cv.}\;(q^2=0.856)$ and non cross-validated conventional coefficient(${r^2}_{ncv.}=0.964)$). The structural distinctions of the highest active molecules were able to understand from the interaction between pOBP and green odorants in the contour maps with CoMSIA model.

Comparative Molecular Field Analyses on the Herbicidal Activities of New 5-benzofuryl-2-[1-(alkoxyimino)alkyl]-3-hydroxycyclohex-2-en-1-one Derivatives (새로운 5-benzofuryl-2-[1-(alkoxyimino)alkyl]-3-hydroxycyclohex-2-en-1-one 유도체들의 제초활성에 관한 비교 분자장 분석)

  • Chung, Ki-Sung;Jang, Seok-Chan;Choi, Kyung-Seob;Sung, Nack-Do
    • Applied Biological Chemistry
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    • v.49 no.3
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    • pp.238-242
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    • 2006
  • The herbicidal activities against the pre-emergence of rice plant (Oryza sativa L.) and barnyard grass (Echinochloa crus-gall) with changing substituents $(R_1-R_4)$ of new 5-benzofuryl-2-[1-(alkoxyimino) alkyl]-3-hydroxycyclohex-2-en-1-one derivatives as substrate molecules were studied quantitatively using comparative molecular field analyses (CoMFA). The optimized CoMFA models (rice plant: A5 & barnyard grass: B3) were derived from atom based fit alignment and a combination of CoMFA fields. The two models for herbicidal activity against two plants showed the best predictability and fitness ($q^2$>0.6 & ${r^2}_{ncv.}$>0.94) for the herbicidal activities. Also, CoMFA-HINT contour maps showed that the selective herbicidal activity between rice plant and barnyard grass depends on the hydrophobicity of $R_2\;and\;R_3$ groups in molecule. Therefore, it is expected that the herbicidal activity against barnyard grass will be improved by the introduction of the steric bulk small and hydrophobic group.

Modeling and Optimization of Dough Properties Using Response Surface Design (반응표면분석법을 이용한 반죽물성의 모델링 및 최적화)

  • Lee, Kooyeon;Choi, Gwkang Seok;Kim, Tae Woo;Cho, Kwan Hyung;Kang, Dongjin;Kim, Sung Tae;Jang, Dong-Jin
    • Food Engineering Progress
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    • v.21 no.2
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    • pp.132-137
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    • 2017
  • The purpose of this study was to optimize dough properties using response surface methodology (RSM) and to demonstrate the performances of dough prepared under optimized conditions. Dough mixed with yeast, margarine, salt, sugar and wheat flour was prepared by fermentation process. Hardness, cohesiveness and springiness of dough were selected as critical quality attributes. The critical formulations (yeast and water) and process (fermentation time) variables were selected as critical input variables based on preliminary experiment. Box-Behnken design (BBD) was used as RSM. As a result, the quardratic, the squared and the linear model respectively provided the most appropriate fit ($R^2$>90) and had no significant lack of fit (p>0.05) on critical quality attributes (hardness, cohesiveness and springiness). The accurate prediction of dough characteristics was possible from the selected models. It was confirmed by validation that a good correlation was obtained between the actual and predicted values. In conclusion, the methodologies using RSM in this study might be applicable to the optimization of fermented foods containing various wheat flour and yeast.

An Analysis of Eco-corridors in Korea by Case Study of Domestic and Foreign Cases (생태통로 조성 국내외 사례 조사를 통한 개선과제 연구)

  • Kim, Myoung-Soo;Heo, Hag-Young;Cho, Soo-Min;Shin, Su-An;Ahn, Tong-Mahn
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.8 no.2
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    • pp.41-55
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    • 2005
  • In an effort to preserve biodiversity in increasingly fragmented green patches, Korea has been installing eco-corridors over or under some arterial or expressways. In a survey of 43 such eco-corridors installed up until the year 2003, some problems and issues were identified. Some selected overseas eco-corridors were also investigated to find implications for the improvements of future installations in Korea. Major findings are; - For most existing eco-corridors, target species are not specified and locations of the eco-corridors are not well considered, and consequently it is questionable if wildlifes are crossing them - Most of existing eco-corridors lack supporting facilities such as fences that guide wildlife to cross them and prevent them from running into the road - Planting on the eco-corridors is not sufficient, not diverse enough in species, and not very considerate of wildlife but designed and planted in a similar manner as in urban parks - Where target species are not well specified, the location, width, cross section, and other aspects of the eco-corridors can not be optimized - It is suggested that eco-corridors are planned at early stages of road planning so that the number and locations of eco-corridor(s) decided as necessary and even the alignment and design of roads consider the installation of eco-corridors in advance - Monitoring of wildlife crossings is needed for improved eco-corridor planning and design - Nationwide green network plan is desirable to be made first and eco-corridors fit into it.

Development and Adaption of Sustainablility Evaluation Indicators for Chungcheongbuk-Do Province - Adopting Quantitative & Qualitive Indicators - (충청북도 지속가능성 평가지표의 개발 및 적용 - 정량적 정성적 지표의 도입 -)

  • Moon, Seok-ki;Yu, Byong-Deuk
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.19 no.1
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    • pp.85-100
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    • 2016
  • Local Agenda 21 organizations have been founded at the most divisions of local government in Chungcheongbuk-Do, but there has been no methods to monitor the total Sustainable Development trends. For the alternative solution of that problem in the Province, this study purposed (1) to develop Indicators fit to this Province (2) to examine the availability of the developed indicators adopting to each division section. Indicators were developed and examined by fields and Quantity / Quality considerations. As a 1st step, committee-composed with field professionals each-selected and developed Quantitative Sustainable Development Indicators(SDIs) optimized to Chungbuk-Province through critical discussions proposing Qualitative Indicators as a suggestion. In 2nd step, developed Indicators were applied and tested upon each divisions. Statistic data were used to calculate indices. 3rd step is adoption stage of Qualitative Indicators which were tested with questionnaire survey analysis. As a results, SDIs for Chungcheongbuk-Do -38 Quantitative SDIs within 4 provisions of 11 items with 8 Qualitative indicators categorization be put off- is developed. With the application test, 5 Quantitative Indicators- were found to be not adaptable because of lack or none of statistic data. Among the 8 Qualitative Indicators, 3 pairs found to be similar results in each pair which needed to be integrated into one. With them, bio-species related and health related Indicators were proposed to be newly added. Nation wide Sustainability comparison between divisions and Ecological Indicator selection are another themes to be considered.