• Title/Summary/Keyword: optimization technique

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Analysis of Trace Levels of Lodinated Trihalomethanes in Water Using Headspace - GC/ECD (Headspace - GC/ECD를 이용한 수중의 미량 요오드계 트리할로메탄류 분석)

  • Son, Hee-Jong;Song, Mi-Jung;Kim, Kyung-A;Yoom, Hoon-Sik;Choi, Jin-Taek
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.1
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    • pp.35-41
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    • 2014
  • Trihalomethanes (THMs) are formed as a results of the reaction of residual chlorine, used as a disinfectant in drinking water, with the organic matter in raw water. Although chlorinated and brominated THMs are the most common disinfection byproducts (DBPs) reported, iodinated THMs (I-THMs) can be formed when iodide is present in raw water. I-THMs have been usually associated with several medicinal or pharmaceutical taste and odor problems and is a potential health concern since they have been reported to be more toxic than their brominated and chlorinated analogs. Currently, there is no published standard analytical method for I-THMs in water. An automated headspace-gas chromatography/electron capture detector (GC/ECD) technique was developed for routine analysis of 10 THMs including 6 I-THMs in water samples. The optimization of the method is discussed. The limits of detection (LOD) and limits of quantification (LOQ) range from 12 ng/L to 56 ng/L and from 38 ng/L to 178 ng/L for 10 THMs, respectively. Matrix effects in river water, sea water and wastewater treatment plant (WWTP) final effluent water were investigated and it was shown that the method is suitable for the analysis of trace levels of I-THMs, in a wide range of waters. The method developed in the present study has the advantage of being rapid, simple and sensitive.

Monte Carlo Simulation of a Varian 21EX Clinac 6 MV Photon Beam Characteristics Using GATE6 (GATE6를 이용한 Varian 21EX Clinac 선형가속기의 6 MV X-선 특성모사)

  • An, Jung-Su;Lee, Chang-Lae;Baek, Cheol-Ha
    • Journal of radiological science and technology
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    • v.39 no.4
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    • pp.571-575
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    • 2016
  • Monte Carlo simulations are widely used as the most accurate technique for dose calculation in radiation therapy. In this paper, the GATE6(Geant4 Application for Tomographic Emission ver.6) code was employed to calculate the dosimetric performance of the photon beams from a linear accelerator(LINAC). The treatment head of a Varian 21EX Clinac was modeled including the major geometric structures within the beam path such as a target, a primary collimator, a flattening filter, a ion chamber, and jaws. The 6 MV photon spectra were characterized in a standard $10{\times}10cm^2$ field at 100 cm source-to-surface distance(SSD) and subsequent dose estimations were made in a water phantom. The measurements of percentage depth dose and dose profiles were performed with 3D water phantom and the simulated data was compared to measured reference data. The simulated results agreed very well with the measured data. It has been found that the GATE6 code is an effective tool for dose optimization in radiotherapy applications.

Reviews of Bus Transit Route Network Design Problem (버스 노선망 설계 문제(BTRNDP)의 고찰)

  • Han, Jong-Hak;Lee, Seung-Jae;Lim, Seong-Su;Kim, Jong-Hyung
    • Journal of Korean Society of Transportation
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    • v.23 no.3 s.81
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    • pp.35-47
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    • 2005
  • This paper is to review a literature concerning Bus Transit Route Network Design(BTRNDP), to describe a future study direction for a systematic application for the BTRNDP. Since a bus transit uses a fixed route, schedule, stop, therefore an approach methodology is different from that of auto network design problem. An approach methodology for BTRNDP is classified by 8 categories: manual & guideline, market analysis, system analytic model. heuristic model. hybrid model. experienced-based model. simulation-based model. mathematical optimization model. In most previous BTRNDP, objective function is to minimize user and operator costs, and constraints on the total operator cost, fleet size and service frequency are common to several previous approach. Transit trip assignment mostly use multi-path trip assignment. Since the search for optimal solution from a large search space of BTRNDP made up by all possible solutions, the mixed combinatorial problem are usually NP-hard. Therefore, previous researches for the BTRNDP use a sequential design process, which is composed of several design steps as follows: the generation of a candidate route set, the route analysis and evaluation process, the selection process of a optimal route set Future study will focus on a development of detailed OD trip table based on bus stop, systematic transit route network evaluation model. updated transit trip assignment technique and advanced solution search algorithm for BTRNDP.

Determination of Optimal Unit Hydrographs and Infultration Rate Functions from Single Rainfall-Runoff Event (단순 강우-유출 사상으로부터 최적단위도와 침투율의 결정)

  • An, Tae-Jin;Ryu, Hui-Jeong;Jeong, Gwang-Geun;Sim, Myeong-Pil
    • Journal of Korea Water Resources Association
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    • v.33 no.3
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    • pp.365-374
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    • 2000
  • This paper is to present the determination of the optimal Joss rate parameters and urnt bydrographs from the observed single rainfall-runoff event using optimization models coupled with a stochastic technique for the global solution. Two kinds of the linear program models are formulated to derive the optimal unit hydrographs and loss rate parameters for gaged basins; one mimmizes the summation of the absolute residual between predlCted and observed runoff ordinates and the other, the maximum absolute residuaL Multistart algorithm which is one or stochastic techniques for the global optimum is adopted to perturb the parameters of the loss rate equations. Multistart efficiently searches the feasIble region to identify the global optimlUll for loss rate parameters, which yields the optimal loss rate parameters and unit hydrograph for Kostiakov's, Plulip's, and Horton's equation. The unique unit hydrograph ordinates for a gIven rainfall-runoff event iS exclusrvely obtained WIth $\Phi$ index, but unit hydrograph ordinates depend upon the parameters [or each loss rate equations. The parameters of Green-Ampt's are determined through a trial and error method. In this paper the single rainfall-nmoff event observed from a watershed is considered to test the proposed method. The optimal unit hydrograph herein found has smaller deviations than the ones reported previously by other researchers.

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Optimal Sensor Allocation for Health Monitoring of Roller-Coaster Structure (롤러코스터의 모니터링을 위한 최적 센서 구성)

  • Heo, Gwang Hee;Jeon, Seung Gon;Park, In Joon
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.15 no.4
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    • pp.165-174
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    • 2011
  • This research aims at the optimal constitution of sensors required to identify the structural shortcoming of roller-coaster. In this research we analyzed the dynamic characteristics of roller-coaster by three dimensional FE modelling, decided on the appropriate location and number of sensors through optimal transducer theory, abstracted the mathematical value of modal features before and after damage on the basis of optimally placed and numbered sensors. and then presented it as a primary information about the basic structure which would be applied to damage estimation. As a target structure, the roller-coater at Seoul Children's Grand Park was chosen and built as a model reduced by one twentieth in size. In order to consider the Kinetics features particular to the roller-coaster structure, we made an exact three-dimensional FE modelling for the model structure by means of Spline function. As for the proper location and number of sensors, it was done by applying EIM and EOT. We also estimated the damage from the combination of strength, flexibility, and model corelation after abstracting the value of modal features. Finally the optimal transducer theory presented here in this research was proved to be valid, and the structural damage was well identified through changes in strength and flexibility. As a result, we were able to present the optimal constitution of sensors needed for the analysis of dynamic characteristics and the development of techniques in dynamic characteristics, which would ultimately contribute to the development of health monitoring for roller-coaster.

Bioconjugation by dual heterobifunctional coupling method: Use of the conjugates for the detection of dopamine (서로 다른 두 작용기를 이용한 결합법에 의한 접합체: 도파민 면역분석법)

  • Ryu, Ji-Eun;Rhee Paeng, In-Sook
    • Analytical Science and Technology
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    • v.23 no.6
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    • pp.537-543
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    • 2010
  • Dopamine (DA) is an important neurotransmitter molecule of catecholamines. Its deficiency could lead to brain disorder such as Parkinson's disease and schizophrenia. Therefore, it is necessary to establish a suitable analytical technique with sensitivity and simplicity. A competitive enzyme-linked immunosorbent assay for DA has been optimized and characterized. Assay sensitivity is controlled by two factors in competitive immunoassay. One is a nature and concentration of competitor, and the other is those of binder, antibody. Thus, optimization was performed: BSA-DA conjugate and antibody-avidin conjugate were prepared by dual heterobifunctional coupling method using SATA and SMCC. Assay condition was optimized with $6.66\;{\mu}gmL^{-1}$ of BSA-DA and $4.17{\times}10^{-10}\;M$ of antibody-avidin conjugate. A dose-response curve was constructed, and a limit of detection and a dynamic range for DA were accomplished to $2.3{\times}10^{-2}\;{\mu}g\;mL^{-1}$ and four orders of magnitude ($1.0{\times}10^{-7}\;M$ to $1.0{\times}10^{-3}\;M$), respectively. Calibration curve was constructed on dynamic range and least-squares regression of this data gave the following relationship: absorbance = -0.1098 log[DA]+0.0353 ($R^2$ = 0.9956).

The Variation of Tagging Contrast-to-Noise Radio (CNR) of SPAMM Image by Modulation of Tagline Spacing (Tagline 간격의 조절을 통한 SPAMM 영상에서의 Tagging 대조도 대 잡음비의 변화)

  • 강원석;최병욱;최규옥;이상호;홍순일;정해조;김희중
    • Progress in Medical Physics
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    • v.13 no.4
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    • pp.224-228
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    • 2002
  • Myocardial tagging technique such as spatial modulation of magnetization (SPAMM) allows the study of myocardial motion with high accuracy. However, the accuracy of the estimation of tag intersection can be affected by tagline spacing. The aim of this study was to investigate the relationship between tagline spacing of SPAMM image and tagging contrast-to-noise ratio (CNR) in in-vivo study. Two healthy volunteers were undergone electrocardiographically triggered MR imaging with SPAMM-based tagging pulse sequence at a 1.5T MR scanner. Horizontally modulated stripe patterns were imposed with a range from 3.6 to 9.6 mm of tagline spacing. Images of the left ventricle(LV) wall were acquired at the mid-ventricle level during cardiac cycle with FE-EPI (TR/TE = 5.8/2.2 msec, FA= 10$^{\circ}$. Tagging CNR for each image was calculated with a software which developed in our group. During contraction, tagging CNR was more rapidly decreased in case of narrow tagline spacing than in case of wide tagline spacing. In the same heart phase, CNR was increased corresponding with tagline spacing. Especially, at the fully contracted heart phase, CNR was more rapidly increased than the other heart phases as a function of tagline spacing. The results indicated that the optimization of tagline spacing provides better tagging CNR in order to analyze the myocardial motion more accurately.

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Quasi-Static Equilibrium of a Propeller Shaft in a Hydrodynamic Oil-Lubricated Stern Tube Bearing (윤활유(潤滑油) 선미관(船尾管) 베어링 축계(軸系)의 준정적(準靜的) 평형상태(平衡狀態)에 관한 연구(硏究))

  • S.Y.,Ahn;S.S.,Kim
    • Bulletin of the Society of Naval Architects of Korea
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    • v.26 no.3
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    • pp.51-61
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    • 1989
  • Recently, the growth in the propulsion power and propeller size of typical energy saving ships has resulted in severe damages of the oil-lubricated stern tube bearing. Consequently, a more rational analytical method for the design of the shafting system is required. In this paper an analytical method applicable to the design of the oil-lubricated stern tube bearing and shafting system is presented. The method consists of the finite element analysis of the shafting system and the oil film hydrodynamics. The shafting system is modeled as a three-dimensional problem using beam elements taking account for the steady components of thrust, lateral forces and moments of the propeller as well as the elastic foundation effects. The oil film hydrodynamics is modeled as a two-dimensional problem. Equal and retangular elements employing hourglass control method are used for the construction of the oil film fluidity matrix. To search the quasi-static equilibrium position between the propeller shaft and the oil film, an optimization technique is employed. Some numerical results based on the proposed method are compared with some measured and numerical data available. They show acceptable agreements with the data.

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PRISM-KNU Development and Monthly Precipitation Mapping in South Korea (PRISM-KNU의 개발과 남한 월강수량 분포도 작성)

  • PARK, Jong-Chul;KIM, Man-Kyu
    • Journal of the Korean Association of Geographic Information Studies
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    • v.19 no.2
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    • pp.27-46
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    • 2016
  • In this study, the parameter-elevation regressions on independent slopes model-Kongju National University(PRISM-KNU) system was developed to interpolate monthly precipitation data. One of the features of PRISM-KNU is that it can adjust the allowable range of slope according to the elevation range in the equation representing a linear relationship between the precipitation and elevation. The parameter value of the model was determined by using the optimization technique, and the result was applied to produce monthly precipitation data with a spatial resolution of $1{\times}1km$ from 2000 to 2014 in South Korea. In the result, the Kling-Gupta Efficiency for model evaluation was over 0.7 in 86% of the total cases simulated. In addition, a dramatic change in the spatial pattern of precipitation data was observed in the output of the Modified Korean PRISM, but such a phenomenon did not occur in the output of the PRISM-KNU. This study confirmed the appropriateness of the PRISM-KNU, and the result showed that the spatial consistency of the data produced by the model improved compared with that produced by the Modified Korean PRISM. It is expected that the PRISM-KNU and its output will be utilized in various studies in the future.

A Study on the Enhancement of Isolation of the MIMO Antenna for LTE/DCS1800/USPCS1900 Handset (LTE/DCS1800/USPCS1900 단말기용 MIMO 안테나의 격리도 개선에 관한 연구)

  • Cho, Dong-Ki;Son, Ho-Cheol;Lee, Jin-Woo;Lee, Sang-Woon;Lee, Mun-Soo
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.10
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    • pp.80-85
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    • 2010
  • In this paper, a MIMO antenna is proposed for LTE/DCSl800/USPCSl900 handset applications. The proposed antenna is based on the IFA and its wide bandwidth is obtained by using a stagger tuning technique. To improve the isolation, a suspended line is connected to the shorting points in two antennas, and capacitors and inductors are added to the connected suspended line. Two identical antennas of which dimension is 2.8cc($40{\times}10{\times}7mm$) are mounted on the two end lines of the system ground plane($40{\times}60mm$). Analysis of the antenna performance and optimization is performed using CST Microwave Studio. The bandwidths are satisfied for LTE band class 13(746-787MHz), class 14(758-798MHz) and DCSl800/USPCSl900 band (1710-1990MHz). The isolations between two antennas are about -12dB for LTE band and -10dB for DCSl800/USPCSl900 band. And the radiation efficiency of each antenna is about for LTE band 33% and 45% for DCSl800/USPCSl900 band respectively.