• Applied Chemistry for Engineering
• /
• v.16 no.6
• /
• pp.790-793
• /
• 2005

Recently, the interest in the extension of human life and personal health has been increased. Accordingly, many researchers in a pharmacy and a medical world have been making efforts to improve the sustained drug release property and the stability of drug release property in a body. Many biological researches have demonstrated that chitosan derivatives are effective, safe absorption enhancers that can improve the delivery efficiency of drug and vaccine, and they are suitable for controlled drug release because they have good stability, bio-compatibility, and biodegradability. In this study the experiment was performed in vivo by utilizing chitosan nanoparticles as a biopolymer to control drug delivery rate at an optimal temperature, pH, and concentration. It was observed that nanoparticles containing insulin could effectively control the blood glucose at a low level.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.58 no.1
• /
• pp.8-14
• /
• 2013

The newly developed fertilizer is the slow-releasing fertilizer which can be used as a basal fertilizer without no additional fertilization at tillering stage. It has 30-4-6% of $N-P_2O_5-K_2O$ and was coated with mixture of LDPE (Low density polyethylene), EVA (Ethylene vinyl acetate), BDP (Bio degraded polymer), TALC and nonionic surfactant for the controlled release up to 50 days after application. Coating materials were designed to be decomposed naturally. This fertilizer can be applied directly to the seedling tray mechanically just before transplanting, resulting in significant labor saving effect. The developed slow-release fertilizer, which can replace both basal fertilization and top dressing at tillering stage by single application directly to seedling tray, showed the highest release at 14~21 days after transplanting. Considering the plant growth at different growth stages and yield, the optimal application rate of developed slow-release fertilizer was 300 g per rice nursery tray and the yield of rice at this application rate was 5.25 MT/ha. Rice quality in terms of head rice grain ratio, amylose content, whiteness, and taste value decreased as fertilization rate increased from 200 g to 500 g per nursery tray. Fertilization rate based on quantity of fertilizer ingredients (N, P, K) was reduced by 49.3% compared to the standard application rate and there was 49.2% reduction in labor input for fertilization.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.18 no.7
• /
• pp.554-564
• /
• 2017

The purpose of this study is to assist farmers in determining the optimal time for the shipment of stored apples by investigating the market trends, storage status and release dates of low-temperature stored apples. We surveyed 300 apple cultivation farms in Daegu, Gyeongbuk Province, which is the main producer of apples, and examined the cultivars, cultivation areas, storage conditions, and shipment status of apples. The main results are as follows: the proportion of apples cultivatedat different ripening times was surveyed. According to the results, the proportions of early, middle and late varieties were 78.3%, 63.7% and 96.0%, respectively. Also, 48.7% of the farm households surveyed had cold storage facilities. The average storage cost per apple box(15kg) was 978.3 won for self-storage and 1,771.8 won for consignment storage. For the six(6) months between November and April, the proportion of shipped apples was 91.6% of the total stored apples. The (average total?)annual apple shipment, including apples stored in general storage warehouses, was 744.4 boxes. The (average total?) annual shipment of cold storage apples was 616 boxes. The stored apples were mainly shipped to 'wholesale markets', which have the highest sales share, followed by 'production site collectors' and then 'supermarkets'. The most common shipping method of the apples was by general trucks, followed by low-temperature trucks, and finally by delivery services. The analysis of the factors influencing the decision to release apples by period showed that it was affected by the storage cost, loss rate, and customary shipping in the off-season(from May to August). On the other hand, in the general release season(from November to April), the statistically significant decision factors for the release of apples were the future expected price, storage cost and decision of the leading farmer groups. For farmers with a high share of general shipment, the deciding factors for the release of apples were the future expected price, storage cost, high income expectation, and decision by leading farmers.

• Journal of Preventive Medicine and Public Health
• /
• v.21 no.1 s.23
• /
• pp.195-206
• /
• 1988

Two major issues of the blood bank management are quality assurance and inventory control. Recently, in Korea blood donation has gained popularity increasingly to allow considerable improvement of the quality assurance with respect to blood collection, transportation, storage, component preparation skills and hematological tests. Nevertheless the inventory control, the other issue of blood bank management, has been neglected so far. For the supply of blood by donation barely meets the demand, the blood bank policy on the inventory control has been 'the more the better.' The shortage itself by no means unnecessitate inventory control. In fact, in spite of shortage, no small amount of blood is outdated. The efficient blood inventory control makes it possible to economize the blood usage in the practice of state-of-the-art medical care. For the efficient blood inventory control in Korean hospitals, this tudy is to develop formulae forecasting the standard blood inventory level and suggest a set of policies improving the blood inventory control. For this study informations of $A^+$ whole bloods and packed cells inventory control were collected from a University Hospital and the Central Blood Bank of the Korean Red Cross. Using this informations, 1,461 daily blood inventory records were formulated.48 varieties of blood inventory control environment were identified on the basis of selected combinations of 4 inventory control variables-crossmatch, transfusion, inhospital donation and age of bloods from external supply. In order to decide the optimal blood inventory level for each environment, simulation models were designed to calculate the measures of performance of each environment. After the decision of 48 optimal blood inventory levels, stepwise multiple regression analysis was started where the independent variables were 4 inventory control variables and the dependent variable was optimal inventory level of each environment. Finally the standard blood inventory level decision rule was developed using the backward elimination procedure to select the best regression equation. And the effective alternatives of the issuing policy and crossmatch release period were suggested according to the measures of performance under the condition of the standard blood inventory level. The results of this study' were as follows ; 1. The formulae to calculate the standard blood inventory level($S^*$)was $S^*=2.8617X(d)^{0.9342}$ where d is the mean daily crossmatch(demand) for a blood type. 2. The measures of performace - outdate rate, average period of storage, mean age of transfused bloods, and mean daily available inventory level - were improved after maintenance of the standard inventory level in comparison with the present system. 3. Issuing policy of First In-First Out(FIFO) decreased the outdate rate, while Last In-First Out(LIFO) decreased the mean age of transfused bloods. The decrease of the crossmatch release period reduced the outdate rate and the mean age of transfused bloods.

• KSII Transactions on Internet and Information Systems (TIIS)
• /
• v.11 no.2
• /
• pp.1089-1104
• /
• 2017

We have developed an information management tool for the EDISON (EDucation-research Integration through Simulation On the Net) open platform. EDISON is, at present, a web-based simulation service for education and research in five computational areas, namely, nanophysics, fluid dynamics, chemistry, structural dynamics, and computer aided optimal design. The EDISON open platform consists of three tiers: EDISON application framework, EDISON middleware, and EDISON infra-resources. The platform provides web portals for education and research in areas such as computational fluid dynamics, computational chemistry, computational nanophysics, computational structural dynamics, and computer aided optimal design along with user service. The main purpose of this research is to test the behavior of the release version of the EDISON Open-Platform under normal operating conditions. This management tool has been implemented using the RESTful API designed in EDISON middleware. The intention is to check co-operation between the middleware and the infrastructure. Suggested tools include User management, Simulation and Job management, and Simulation software (i.e., solver) testing. Finally, it is considered meaningful to develop a management tool that is not supported in other web-based online simulation services.

• Proceedings of the Korean Institute of Building Construction Conference
• /
• 2018.05a
• /
• pp.109-110
• /
• 2018

Preloading Strut applied during installation of the wall jack, but additionally serves to minimize the displacement of soil pressure acting upon dissolution due to the difficulty. In this study, we developed an index of support for the release of stress to facilitate the dismantling of the strut uninstall. The refractive support the axial force acting on the strut are supportable, is refracted at minimum load, disassembly should be easy. In order to find the optimal shape and structural stability of the refractive support We have performed the numerical analysis and performance test to determine the final model. We carried out model tests and UTM test in order to understand the refractive performance and durability of the refractive support for optimal model. Results of the test UTM is refracted all shot 5 times within a target hit number, it was found that there is no problem of the refractive performance. Further, the results of model experiments, it was found that to ensure sufficient durability more than the performance target value of the pin joint support structure.

• Journal of Multimedia Information System
• /
• v.5 no.2
• /
• pp.91-98
• /
• 2018

We devised a bird-borne transceiver unit for S-band packet radio communications based on the CC2500 transceiver, a device manufactured by Texas Instruments (TI). Our assessments determined the optimal parameters needed to achieve successful bird-to-center communication over a distance of 18 km and bird-to-bird communication over a distance of 200 m. These parameters included optimal modulation methods, transmission rates, and antennas. We equipped the transceiver unit with a modified dipole antenna (collinear antenna), which we tested in a 10 m anechoic chamber. Our experimental assessments and circuit design review identified the following parameters: 2FSK modulation method; 14.28 kHz frequency shift; 101.56 kHz IF reception bandwidth; and Manchester encoding (+). Our assessments showed bird-to-bird communications could be achieved over a distance of 200 m assuming MSK, FEC (+), and 500 kbps. Following tests by an official body, we obtained 28 sets of a type approval license for 2.4 GHz. In cooperation with the Yamashina Institute for Ornithology, we attempted to tag and release six or more swans. This unit gives us the ability to obtain vital data on swans. We expect this data to provide significant benefits, including clues on improving screening for infected individuals.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2020.06a
• /
• pp.171-171
• /
• 2020

Decision making strategies should consider both adaptiveness and robustness in order to deal with two main characteristics of climate change: non-stationarity and deep uncertainty. Especially, robust strategies are different from traditional optimal strategies in the sense that they are satisfactory over a wider range of uncertainty and may act as a key when confronting climate change. In this study, a new framework named Robust Stochastic Dynamic Programming (R-SDP) is proposed, which couples previously developed robust optimization (RO) into the objective function and constraint of SDP. Two main approaches of RO, feasibility robustness and solution robustness, are considered in the optimization algorithm and consequently, three models to be tested are developed: conventional-SDP (CSDP), R-SDP-Feasibility (RSDP-F), and R-SDP-Solution (RSDP-S). The developed models were used to derive optimal monthly release rules in a single reservoir, and multiple simulations of the derived monthly policy under inflow scenarios with varying mean and standard deviations are undergone. Simulation results were then evaluated with a wide range of evaluation metrics from reliability, resiliency, vulnerability to additional robustness measures. Evaluation results were finally visualized with advanced visualization tools that are used in multi-objective robust decision making (MORDM) framework. As a result, RSDP-F and RSDP-S models yielded more risk averse, or conservative, results than the CSDP model, and a trade-off relationship between traditional and robustness metrics was discovered.

• Ocean Systems Engineering
• /
• v.14 no.2
• /
• pp.157-169
• /
• 2024

The sudden release of water from a dam failure can trigger bores on a flat surface and exert substantial impact forces on structures. This flow poses a high-risk flood hazard to downstream urban areas, making it imperative to study its impact on structures and devise effective energy dissipators to mitigate its force. In this study, a combination of Genetic Algorithm optimization and numerical modeling is employed to identify the optimal energy dissipator. The analysis reveals that a round arc-shaped structure proves most effective, followed by a triangular shape. These shapes offer wide adaptability in terms of structure dimensions. Structures with higher elevation, especially those with round or triangular shapes, demonstrate superior energy dissipation capabilities. Conversely, square-shaped structures necessitate minimal height to minimize impact forces. The optimal width for dissipating energy is found to be 0.9 meters, allowing for effective wave run-up and propagation. Furthermore, the force exerted on structures increases with higher initial water levels, but diminishes with distance from the dam, highlighting the importance of placement in mitigating impact forces.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.64 no.3
• /
• pp.204-212
• /
• 2019

The optimal application rate of a controlled release fertilizer (CRF) on the growth, yield, and seeding time of rice grown on seedling trays was investigated. The experimental field was located at $37^{\circ}22^{\prime}10^{{\prime}{\prime}}N$ latitude and $127^{\circ}03^{\prime}85^{{\prime}{\prime}}E$ longitude in Hwaseong, Gyeonggi-do, Republic of Korea. The soil in the paddy field was a clay loam. The CRF used in the experiment contained $300g\;kg^{-1}$ of nitrogen, $60g\;kg^{-1}$ of phosphate, and $60g\;kg^{-1}$ of potassium, respectively. The CRF was applied at the rate of 0, 200, 300, 400, 500, and 600 grams on rice seedling tray compared with the field application based on soil testing (control), respectively. The CRF can be applied as single application(which can replace basal fertilizer application and two top dressing application) directly to the seedling tray, and showed the minimum release at the seedling period. Considering the plant growth, nitrogen use efficency and yield of rice, the optimal application rate of developed CRF was 500 g per seedling tray and the yield of rice at this application rate was $4.92{\sim}5.04Mg\;ha^{-1}$. The regression formula between the rice yield and application rates of CRF was as follows ; "$Y=0.0002{\chi}^2+0.0963{\chi}+411.6$($R^2$ : 0.9922) in 2010 and $Y=8E-6{\chi}^2+0.2723{\chi}+344.04$($R^2$:0.9864) in 2011, Y : Rice yield ($Mg\;ha^{-1}$), ${\chi}$ : Application rate (grams) of controlled release fertilizer". The optimum application rates of CRF per rice seedling tray by regression formula was 498 grams in 2010 and 513 grams in 2011.